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ANAARIADGPVAETGYGPVRGTDDGTAKAWLGIRYARAPIGELRWRAPEPPASWHDVFDATRVGAVCPQA TDARIPIDLGGKQDEDSLVLNVWAPSGCRPGDRRPVMVWVHGGAYVLGSASQPLCRGRVLASEGDVVVVT VNYRLGPFGFLDLSEYSSRAMRFDTNLGLRDVIFALQWVRDNIAAFGGDPSRVTLFGESAGGGMITTLLA SPAAEGLFSAAIAQSSPATSVYDAERSRRVARALLERLLIEPDDAARLAHVPIPAILGASQQIFNEVPAQ SPGTLAFAPIVDGDVVPDYPVQAARAGRTHRVPLIIGTNKHEASLFRWMKSPLMPITPEAIRAMFEGIAS EQPGLALPTEEEIRAAYSGMRTKAIGMGVARDIGFRMPTLWFADGHSTSAPVYLYRFDFATPMLRLLRLG AAHATELPYVWGNLAAGPKDPTFKMGGLKQGRKVSQRIRRRWVNFATTGEPTGALGEPVWRRYRREDRAA LVIDKQDKTVTDLDQQLQAAWGDQVLNFR*
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. smegmatis MC2 155 | MSMEG_3667 | - | - | 100% (520) | para-nitrobenzyl esterase |
| M. smegmatis MC2 155 | MSMEG_3002 | - | 5e-83 | 38.75% (511) | para-nitrobenzyl esterase |
| M. smegmatis MC2 155 | MSMEG_3848 | - | 6e-80 | 39.01% (505) | para-nitrobenzyl esterase |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb2071c | lipT | 8e-76 | 37.62% (505) | carboxylesterase LipT |
| M. gilvum PYR-GCK | Mflv_3419 | - | 0.0 | 63.90% (518) | carboxylesterase, type B |
| M. tuberculosis H37Rv | Rv2045c | lipT | 8e-76 | 37.62% (505) | carboxylesterase LipT |
| M. leprae Br4923 | MLBr_00314 | - | 4e-06 | 27.82% (133) | putative esterase |
| M. abscessus ATCC 19977 | MAB_3453c | - | 2e-82 | 38.93% (506) | carboxylesterase LipT |
| M. marinum M | MMAR_4363 | - | 0.0 | 61.61% (521) | carboxylesterase |
| M. avium 104 | MAV_1226 | - | 0.0 | 61.91% (512) | carboxylesterase superfamily protein |
| M. thermoresistible (build 8) | TH_3679 | - | 0.0 | 65.13% (519) | PUTATIVE Carboxylesterase, type B |
| M. ulcerans Agy99 | MUL_2261 | lipT | 6e-77 | 39.29% (509) | carboxylesterase, LipT |
| M. vanbaalenii PYR-1 | Mvan_3172 | - | 0.0 | 66.40% (509) | carboxylesterase, type B |
CLUSTAL 2.0.9 multiple sequence alignment
Mb2071c|M.bovis_AF2122/97 -------------MALESATVGSMHERTVRARTATGIVEG----FTRDG-
Rv2045c|M.tuberculosis_H37Rv -------------MALESATVGSMHERTVRARTATGIVEG----FTRDG-
MUL_2261|M.ulcerans_Agy99 -----------------------MHERTVRARTATGVVEG----FTRDG-
MAB_3453c|M.abscessus_ATCC_199 -------------------MASGSKTPTVRVTTPNGIVEG----FVRGG-
Mflv_3419|M.gilvum_PYR-GCK --------------MTAEATPRSSA---PVVDTSTGPVRG-----LDDGI
Mvan_3172|M.vanbaalenii_PYR-1 --------------MTADATTRSSAGGRPVVETTNGPVRG-----VDDGS
MSMEG_3667|M.smegmatis_MC2_155 ---------------MANAARIADG---PVAETGYGPVRG-----TDDGT
TH_3679|M.thermoresistible__bu MPSTTPPDDRTPDDAPTRPAPAHSAVGSPVVDTVHGPVRG-----RDDGV
MMAR_4363|M.marinum_M --------------MTSDIRRMASDG--YVVETAYGPVRGAEDGIAAAGS
MAV_1226|M.avium_104 ---------------------MAVDD--LVVETGYGPVR----GVPVDG-
MLBr_00314|M.leprae_Br4923 -------------------MAISAGAPVEIVESGPSIAAR----------
. : . .
Mb2071c|M.bovis_AF2122/97 ---VHRWRSIPYARAPVGSLRFRAPQPAQPWPGVRHCHTFANCAPQQRRY
Rv2045c|M.tuberculosis_H37Rv ---VHRWRSIPYARAPVGSLRFRAPQPAQPWPGVRHCHTFANCAPQQRRY
MUL_2261|M.ulcerans_Agy99 ---VHRWRSIPYARAPIGLLRFRAPRPPQPWSGVRHCHGFTHCSPQQRRY
MAB_3453c|M.abscessus_ATCC_199 ---VRRFRSIPYARPPIGLLRLRAPQPALPWEGVRDCTEFGAAAPQRRRY
Mflv_3419|M.gilvum_PYR-GCK ---IKSWKGVPYAAAPVGELRWRAPEPPPAWTEPRDATRVGPVCPQPTDP
Mvan_3172|M.vanbaalenii_PYR-1 ---VKSWKAVRYAAAPVGELRWRAPEPPQAWSEPVDAGRVGPVCPQPTDP
MSMEG_3667|M.smegmatis_MC2_155 ---AKAWLGIRYARAPIGELRWRAPEPPASWHDVFDATRVGAVCPQATDA
TH_3679|M.thermoresistible__bu ---VKVWRGIRYAAAPVGGLRWRAPEPPQPWREPMDAIRVGPACPQPADP
MMAR_4363|M.marinum_M GVRTKSWKGIRYGAPPVGELRFRAPQPPQPWTEIADATAFGPVCPQPVLA
MAV_1226|M.avium_104 ---VKAWKGIRYAAPPIGDLRFRAPQPPERWTEVADATVFGPACPQPVFP
MLBr_00314|M.leprae_Br4923 ----LASLTSRLTIRPILAVGSYVPQLPWPFGLIDHAARVLLPVTNAARA
*: : .*. . : .. . .:
Mb2071c|M.bovis_AF2122/97 TVMGIGRYQTRSEDCLTLNVVTPEEPAT-QPLPVMVFIHGGGYILGSSAT
Rv2045c|M.tuberculosis_H37Rv TVMGIGRYQTRSEDCLTLNVVTPEEPAT-QPLPVMVFIHGGGYILGSSAT
MUL_2261|M.ulcerans_Agy99 TMLGLGKYQPMSEDCLTLNVVAPEAPTH-RPLPVMVFIHGGGYILGSSAT
MAB_3453c|M.abscessus_ATCC_199 RVLGPGRVQRASEDCLTVNVVTPDRPSN-EPLPVMFFIYGGGYLLGSSAT
Mflv_3419|M.gilvum_PYR-GCK KIP-LDLGAPQGEDFLSLNVWAPSGTQPGDRKPVMVWVHGGAYVLGSASQ
Mvan_3172|M.vanbaalenii_PYR-1 RIP-IDLGAPQGEDFLTLNIWAPSGTQPGDAKPVMVWIHGGAYILGSASQ
MSMEG_3667|M.smegmatis_MC2_155 RIP-IDLGGKQDEDSLVLNVWAPSGCRPGDRRPVMVWVHGGAYVLGSASQ
TH_3679|M.thermoresistible__bu RIP-LDLGAAIGEDCLNLNVWASSDTEPGDRKPVLVWVHGGAYVIGAASQ
MMAR_4363|M.marinum_M NMP-IDLGAPQDEDCLRLNIWAPANTAPGAAKPVMVWLHGGAYMLGSASQ
MAV_1226|M.avium_104 NMP-LDLGAPQGEDCLRLNVWASADTQPGDAKPVMVWLHGGAYVLGSSSQ
MLBr_00314|M.leprae_Br4923 EVN---LSNTSAQLVRAAGVRPADGSGR-----IVLYLHGGAFLGCGANS
: : .: .. ::.:::**.:: .:
Mb2071c|M.bovis_AF2122/97 PIYDGAALARRG-CVYVSVNYRLGALGCLDLSSLSTPQITLDSNVYLRDL
Rv2045c|M.tuberculosis_H37Rv PIYDGAALARRG-CVYVSVNYRLGALGCLDLSSLSTPQITLDSNVYLRDL
MUL_2261|M.ulcerans_Agy99 PIYDGAALARRG-CVYVSVNYRLGALGCLDLSSLSTPDIAIDGNLYLRDL
MAB_3453c|M.abscessus_ATCC_199 PLYDGAALARRG-CVYVSVNYRVGALGALDLSSLSDRDHTIDGNLFLRDV
Mflv_3419|M.gilvum_PYR-GCK PLYHGRAMAGAGDVIVVTVNYRLGALGFLELSTLD-DSGRFASNLGLRDV
Mvan_3172|M.vanbaalenii_PYR-1 PLYHGGTLASGGDAVVVTVNYRLGALGFLELSTLGADPERFATNLGLRDV
MSMEG_3667|M.smegmatis_MC2_155 PLCRGRVLASEGDVVVVTVNYRLGPFGFLDLSEYSSRAMRFDTNLGLRDV
TH_3679|M.thermoresistible__bu PLYHGRELVRRGDVVLVTLNYRLGAFGFLELTALSSGRRRFDTNVGLRDV
MMAR_4363|M.marinum_M ALYDGRRLASSGEVIVVTVNYRLGALGFLDLSSLSHAGRSFDSNVGLRDV
MAV_1226|M.avium_104 TLYDGRRLVSHGDVVVVTVNYRLGALGFLDLSSLNSAGRSFDSNVGLRDV
MLBr_00314|M.leprae_Br4923 HRRLVETLSKLADSPILVVNYRLLPK--------------HSIGMALDDC
: . : :***: . .: * *
Mb2071c|M.bovis_AF2122/97 VLALRWVHDNIAEFGGDPGNVTIFGESAGAHITATLLAVPAAKGLFARAI
Rv2045c|M.tuberculosis_H37Rv VLALRWVHDNIAEFGGDPGNVTIFGESAGAHITATLLAVPAAKGLFARAI
MUL_2261|M.ulcerans_Agy99 VMALQWIQDNIAEFGGDPDNVTIFGESAGAHITATLLAVPAAKGLFARAI
MAB_3453c|M.abscessus_ATCC_199 VLALQWVHDNIGTFGGDPGNVTIFGESAGAHCVETLMATPAAAGLFHRAI
Mflv_3419|M.gilvum_PYR-GCK LAALGWVRDNIAAFGGDPGRVTVFGESAGGGIVTSLLGSPAAAGLFHAAI
Mvan_3172|M.vanbaalenii_PYR-1 LAALEWVRDNIAAFGGDPGRVTVFGESAGGGIVASLLASPAAAGLFSAAI
MSMEG_3667|M.smegmatis_MC2_155 IFALQWVRDNIAAFGGDPSRVTLFGESAGGGMITTLLASPAAEGLFSAAI
TH_3679|M.thermoresistible__bu LFALAWVRDNIAAFGGDPDRVTLFGESAGGGIVTTLLGSPAAAGLFHRAI
MMAR_4363|M.marinum_M LAALHWVRENIAAFGGDPANITLFGESAGAGLVTTLLVTPAARGLFSRAI
MAV_1226|M.avium_104 LAALEWVRDNITAFGGDPRRVTLFGESAGAGIVTTLLASPAAAGLFAAAI
MLBr_00314|M.leprae_Br4923 HDGYQWLRR----LGYDPEQIVLAGDSAGGYLALALAQRLQDVGEEPAAL
. *:: :* ** .:.: *:***. :* * *:
Mb2071c|M.bovis_AF2122/97 SESPAAGMVRSREVAAEFAARFANLIGARTQDAANALMQASPAQ--LVEA
Rv2045c|M.tuberculosis_H37Rv SESPAAGMVRSREVAAEFAARFANLIGARTQDAANALMQASPAQ--LVEA
MUL_2261|M.ulcerans_Agy99 SESPAAGMVRPREIAAEFATRFARLLGARKHDAASALMRATAAQ--LVQT
MAB_3453c|M.abscessus_ATCC_199 CQSTASGMAVPADSAAMYAQKFAQILGATTQSAAETVLRSSPAE--LGAA
Mflv_3419|M.gilvum_PYR-GCK AQSSPATSMYDVGRARRVATRFLEVIGVDRADMS-ALTTAPISA--LVEA
Mvan_3172|M.vanbaalenii_PYR-1 AQSAPVTSTYELGRAQRVAERFLDVLGARPDDLH-RLSEAPIDV--LVEA
MSMEG_3667|M.smegmatis_MC2_155 AQSSPATSVYDAERSRRVARALLERLLIEPDDAA-RLAHVPIPA--ILGA
TH_3679|M.thermoresistible__bu AQSSPATSCYGTERAIDVAEQFLGHLGLSPRDVD-RLPDVPVAA--IVEV
MMAR_4363|M.marinum_M AQSSPATSVYDRERAQRVAVHLLDKLGVAASDVD-KLTQLPTAA--IVAA
MAV_1226|M.avium_104 AQSSPATSVYDRDRAARVAEAFLGKLGITASESR-RLIDMPMAA--ILAA
MLBr_00314|M.leprae_Br4923 VAISPLLQLAKKGKQAHPNAKTDAMFPPKAFDALGRLVASSAAKNKVDDK
.. : . : . :
Mb2071c|M.bovis_AF2122/97 QHHLIRQGMRKRLG-AFPIGPVFGDDYLPMDPVEAMRSGRVHAVPLIVGT
Rv2045c|M.tuberculosis_H37Rv QHHLIRQGMRKRLG-AFPIGPVFGDDYLPMDPVEAMRSGRVHAVPLIVGT
MUL_2261|M.ulcerans_Agy99 QHRLIDQGMQKRLG-AFPIGPTFGDDCLPLDPVEAMRAGQSHKVPLIVGT
MAB_3453c|M.abscessus_ATCC_199 LNMLIADIVTNMPGGSFAIGPCIDGHYLPRHPIEAMEHGEAHRVPLIVGH
Mflv_3419|M.gilvum_PYR-GCK SRTVFNEVPVRTPG-TLAFAPTIDGDLLPDYPVNLARNGKTHPVPLLIGT
Mvan_3172|M.vanbaalenii_PYR-1 SRTVFDEVPVRTPG-TLAFAPTVDGDLLPDYPVNLARQGRTHPVPLIIGT
MSMEG_3667|M.smegmatis_MC2_155 SQQIFNEVPAQSPG-TLAFAPIVDGDVVPDYPVQAARAGRTHRVPLIIGT
TH_3679|M.thermoresistible__bu SKHVFDDVPARRPG-TLAFAPIVDGDIVPDYPVALARAGRTLPVPLVIGT
MMAR_4363|M.marinum_M STEVFNEVPVRNPG-TLAFVPIVDGDVLTDYPVKVAQEGRSHPVPLLIGT
MAV_1226|M.avium_104 SQQVFDEVPVRNPG-TLAFVPIVDGDVLADYPVKVAQQGCSHPVPLIIGT
MLBr_00314|M.leprae_Br4923 PEELYEPLDHIAPGLPRTLIHVSGSEVLLHDAQLAATKLAAVGVPAEIRV
: * . .: ... : . ** :
Mb2071c|M.bovis_AF2122/97 NAEEGRLFTRFLG-MLPTNEPMVEELLSGMKPA-------DRERITAAYP
Rv2045c|M.tuberculosis_H37Rv NAEEGRLFTRFLG-MLPTNEPMVEELLSGMKPA-------DRERITAAYP
MUL_2261|M.ulcerans_Agy99 NADEGRLFTRFLK-MLPTNKAMIDELLADTEPA-------TRERITAAYP
MAB_3453c|M.abscessus_ATCC_199 NADEAKLFTRVLK-MMPLSESALEGMLARGGPG-------HRDRIVAAYP
Mflv_3419|M.gilvum_PYR-GCK NKNEAALFRYMKSPLMPVAPESVRAMFAEISAEQPTLQLPSEDHLRGIYR
Mvan_3172|M.vanbaalenii_PYR-1 NKNEAALFRYMKSPLMPIAPASIKAMFAEIAAEQPGLQLPSEDILKGTYR
MSMEG_3667|M.smegmatis_MC2_155 NKHEASLFRWMKSPLMPITPEAIRAMFEGIASEQPGLALPTEEEIRAAYS
TH_3679|M.thermoresistible__bu NKDEASLFRWMKSPLLPITPDAIKKMFADIAAEQPGLRLPTETQISAAYR
MMAR_4363|M.marinum_M NKHEAALFRLMRSPLMPITPRAITSMFTQIAAEQPDLQLPTEEEIGLAYS
MAV_1226|M.avium_104 NQHEAALFRLMRSALMPITPHAITSMFNQIAAEQPDLQLPTEKQIGSAYS
MLBr_00314|M.leprae_Br4923 WPGQVHVFQAAAP-------------------------------------
: :*
Mb2071c|M.bovis_AF2122/97 NYPAPSACIQLGGDFAFSSAAWQIAEAHGANAPTYLYRYDYAPRTLRWSG
Rv2045c|M.tuberculosis_H37Rv NYPAPSACIQLGGDFAFSSAAWQIAEAHGANAPTYLYRYDYAPRTLRWSG
MUL_2261|M.ulcerans_Agy99 NYPESAACIQLGGDFAFNAAAWQIAEAQGVHAPTYLYRYDYAPRTLRWSG
MAB_3453c|M.abscessus_ATCC_199 GYPERSARVKLAGDMNFSTAAWQMAEAHHRYAPVYFYRYDYAPGALRIAG
Mflv_3419|M.gilvum_PYR-GCK G-RGKNHALGLTSDLGFRMPSIWFADGHRAVAPVYLYRFDFATPLLRVAR
Mvan_3172|M.vanbaalenii_PYR-1 G-RGKTKGLGLTSDLGFRMPSLWFADGHRAVAPVYLYRFDFHTPLLRLVR
MSMEG_3667|M.smegmatis_MC2_155 GMRTKAIGMGVARDIGFRMPTLWFADGHSTSAPVYLYRFDFATPMLRLLR
TH_3679|M.thermoresistible__bu RQRGKRLGVGVASDIGFRMPSVWFAEGHTAVAPTYLYRFDWSTPTLRLLR
MMAR_4363|M.marinum_M RLRRRARPLSIATDVGFRMPSVWLAEGHSRVAPVYLYRFDYSTPLLKLLL
MAV_1226|M.avium_104 RFRRRARYLSIATDVGFRMPSVWLAEGHARVAPVYLYRFDYSTPLLRLLM
MLBr_00314|M.leprae_Br4923 --------MVPEATLSLRQISQYIREATASKASRDRQSL-----------
: . : : : :. *.
Mb2071c|M.bovis_AF2122/97 FGATHATELFAVFDIYRTRFGALLTAAADRRAALRVSNEVQRRWRCFSQI
Rv2045c|M.tuberculosis_H37Rv FGATHATELFAVFDIYRTRFGALLTAAADRRAALRVSNEVQRRWRCFSQI
MUL_2261|M.ulcerans_Agy99 FGATHATELFAVFDIYRTRFGALLTAAADRRHALRVSDEVIRRWRSFSQT
MAB_3453c|M.abscessus_ATCC_199 MGATHATELLAVFDSYRGAMGTVMAGALGRRDAVRVSNDVQRRWLAFARS
Mflv_3419|M.gilvum_PYR-GCK LHAAHATELPFVWGNLGSGRKDPTFALGGRKSGTAVSQRMQSRWTNFAAN
Mvan_3172|M.vanbaalenii_PYR-1 LHAAHATELPFVWGNLVAGRRDPTFALGGRKSGAAVSERMRARWVSFAAH
MSMEG_3667|M.smegmatis_MC2_155 LGAAHATELPYVWGNLAAGPKDPTFKMGGLKQGRKVSQRIRRRWVNFATT
TH_3679|M.thermoresistible__bu LGAAHATELPYVFGNLDT-PKDPTFTLGGRRTGRQVSQRIRTRWINFAVH
MMAR_4363|M.marinum_M VRAAHATELPYVWGNLGG-PQDPTLRLGGAKTAKAVSKRMRTRWINFATQ
MAV_1226|M.avium_104 VKAAHATELPYVWGTLGA-PKDPTLKLGGSKTAKAVSKRVRTRWTNFAAH
MLBr_00314|M.leprae_Br4923 --------------------------------------------------
Mb2071c|M.bovis_AF2122/97 GVP-----GDDWPAYTQDDRAVLVFDRRCRIEFDPHQHRRIAWDGFSLAN
Rv2045c|M.tuberculosis_H37Rv GVP-----GDDWPAYTQDDRAVLVFDRRCRIEFDPHQHRRIAWDGFSLAN
MUL_2261|M.ulcerans_Agy99 GTP-----GEDWPAYTHTRRAVMVIDRKSRVEIDPHRHRRLAWDGFSLAR
MAB_3453c|M.abscessus_ATCC_199 GVP-----GDGWPTYGPPDRAVMVFDHATRVELDPEAARRAAWEGFSLTL
Mflv_3419|M.gilvum_PYR-GCK GDPSAPG-APTWRPYDAS-RATLVIDKHDSVVDDLDAHVRRAWGDDVLSF
Mvan_3172|M.vanbaalenii_PYR-1 GAPTGPAGEPVWRPYGADDRATLVIDKQDTVVDDLDADVRRAWGDDVLSF
MSMEG_3667|M.smegmatis_MC2_155 GEPTGALGEPVWRRYRREDRAALVIDKQDKTVTDLDQQLQAAWGDQVLNF
TH_3679|M.thermoresistible__bu GRPDGPPGEPRWHAYDRAERPCLLIDRRDRVVRDVDEPIRLTWGSEVLSF
MMAR_4363|M.marinum_M DNPAGPAGEPDWPAYQDGDRACLVIDKSDRVARDIDAPIRAAWGREVVGF
MAV_1226|M.avium_104 AKPAGPAGSPEWAPYQEQDRACLIIGKNDVLAHDVDAKARAAWGSEMVSF
MLBr_00314|M.leprae_Br4923 --------------------------------------------------
Mb2071c|M.bovis_AF2122/97 -
Rv2045c|M.tuberculosis_H37Rv -
MUL_2261|M.ulcerans_Agy99 -
MAB_3453c|M.abscessus_ATCC_199 -
Mflv_3419|M.gilvum_PYR-GCK L
Mvan_3172|M.vanbaalenii_PYR-1 L
MSMEG_3667|M.smegmatis_MC2_155 R
TH_3679|M.thermoresistible__bu R
MMAR_4363|M.marinum_M R
MAV_1226|M.avium_104 R
MLBr_00314|M.leprae_Br4923 -