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HERTVRARTATGVVEGFTRDGVHRWRSIPYARAPIGLLRFRAPRPPQPWSGVRHCHGFTHCSPQQRRYTM LGLGKYQPMSEDCLTLNVVAPEAPTHRPLPVMVFIHGGGYILGSSATPIYDGAALARRGCVYVSVNYRLG ALGCLDLSSLSTPDIAIDGNLYLRDLVMALQWIQDNIAEFGGDPDNVTIFGESAGAHITATLLAVPAAKG LFARAISESPAAGMVRPREIAAEFATRFARLLGARKHDAASALMRATAAQLVQTQHRLIDQGMQKRLGAF PIGPTFGDDCLPLDPVEAMRAGQSHKVPLIVGTNADEGRLFTRFLKMLPTNKAMIDELLADTEPATRERI TAAYPNYPESAACIQLGGDFAFNAAAWQIAEAQGVHAPTYLYRYDYAPRTLRWSGFGATHATELFAVFDI YRTRFGALLTAAADRRHALRVSDEVIRRWRSFSQTGTPGEDWPAYTHTRRAVMVIDRKSRVEIDPHRHRR LAWDGFSLAR*
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. ulcerans Agy99 | MUL_2261 | lipT | - | 100% (501) | carboxylesterase, LipT |
| M. ulcerans Agy99 | MUL_1819 | lipO | 2e-12 | 35.34% (116) | esterase LipO |
| M. ulcerans Agy99 | MUL_1794 | lipH | 2e-09 | 34.78% (115) | lipase LipH |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb2071c | lipT | 0.0 | 81.80% (500) | carboxylesterase LipT |
| M. gilvum PYR-GCK | Mflv_3125 | - | 0.0 | 66.07% (504) | carboxylesterase, type B |
| M. tuberculosis H37Rv | Rv2045c | lipT | 0.0 | 81.80% (500) | carboxylesterase LipT |
| M. leprae Br4923 | - | - | - | - | - |
| M. abscessus ATCC 19977 | MAB_3453c | - | 1e-168 | 59.07% (496) | carboxylesterase LipT |
| M. marinum M | MMAR_3020 | lipT | 0.0 | 99.00% (501) | carboxylesterase, LipT |
| M. avium 104 | MAV_2466 | - | 0.0 | 81.58% (505) | LppT protein |
| M. smegmatis MC2 155 | MSMEG_3848 | - | 0.0 | 69.26% (501) | para-nitrobenzyl esterase |
| M. thermoresistible (build 8) | TH_0737 | lipT | 0.0 | 68.26% (501) | Probable carboxylesterase LipT |
| M. vanbaalenii PYR-1 | Mvan_3408 | - | 0.0 | 69.52% (502) | carboxylesterase, type B |
CLUSTAL 2.0.9 multiple sequence alignment
MUL_2261|M.ulcerans_Agy99 --------------MHERTVRARTATGVVEGFTRDGVHRWRSIPYARAPI
MMAR_3020|M.marinum_M --------------MHERTVRARTATGIVEGFTRDGVHRWRSIPYARAPI
Mb2071c|M.bovis_AF2122/97 ----MALESATVGSMHERTVRARTATGIVEGFTRDGVHRWRSIPYARAPV
Rv2045c|M.tuberculosis_H37Rv ----MALESATVGSMHERTVRARTATGIVEGFTRDGVHRWRSIPYARAPV
MAV_2466|M.avium_104 --------------MHDRTVRARTATGIVEGFTRDGVHRWRSIPYARPPV
TH_0737|M.thermoresistible__bu -------------VMHEHRVRVQISTGTIEGFTRDGVHRWRAIPYAKPPV
Mvan_3408|M.vanbaalenii_PYR-1 --------------MHEHTVRVRTASGTVEGFTRDGVHRWRSIPYARPPV
MSMEG_3848|M.smegmatis_MC2_155 --------------MHERTVRAEISTGIIEGFTRDGVHRWRSIPYARAPI
Mflv_3125|M.gilvum_PYR-GCK MVRQAGREFDTVGRMHEHTVRVKIASGTVEGFTRDGVHRWRSIPYARPPV
MAB_3453c|M.abscessus_ATCC_199 ----------MASGSKTPTVRVTTPNGIVEGFVRGGVRRFRSIPYARPPI
: **. ..* :***.*.**:*:*:****:.*:
MUL_2261|M.ulcerans_Agy99 GLLRFRAPRPPQPWSGVRHCHGFTHCSPQQRRYTMLGLG----KYQPMSE
MMAR_3020|M.marinum_M GPLRFRAPRPPQPWSGVRHCHGFTHCSPQQRRYTMLGLG----KYQPMSE
Mb2071c|M.bovis_AF2122/97 GSLRFRAPQPAQPWPGVRHCHTFANCAPQQRRYTVMGIG----RYQTRSE
Rv2045c|M.tuberculosis_H37Rv GSLRFRAPQPAQPWPGVRHCHTFANCAPQQRRYTVMGIG----RYQTRSE
MAV_2466|M.avium_104 GDLRFRAPQPAQPWSGVRHCHGFANCAPQQRRYTLLGLSGLGGRYQPMSE
TH_0737|M.thermoresistible__bu GPLRLRAPEPADPWPGVRHCHGFGNCAPQERKYTLIGLG----KYQPMGE
Mvan_3408|M.vanbaalenii_PYR-1 GRLRYRAPEPVQPWSGVRHCHGFLSCAPQHRRYTLIGVR----KYQPTSE
MSMEG_3848|M.smegmatis_MC2_155 GPLRLRAPQPAEPWPGVRYCHGFGFCAPQQRRYTLLGVG----KYQPTSE
Mflv_3125|M.gilvum_PYR-GCK GPLRYRAPRPVQPWPGVRYCHGFGACAPQQRMYTLLAPG----RYQPMSE
MAB_3453c|M.abscessus_ATCC_199 GLLRLRAPQPALPWEGVRDCTEFGAAAPQRRRYRVLGPG----RVQRASE
* ** ***.* ** *** * * .:**.* * ::. : * .*
MUL_2261|M.ulcerans_Agy99 DCLTLNVVAPEAPTHR----PLPVMVFIHGGGYILGSSATPIYDGAALAR
MMAR_3020|M.marinum_M DCLTLNVVAPEAPSHR----PLPVMVFIHGGGYILGSSATPIYDGAALAR
Mb2071c|M.bovis_AF2122/97 DCLTLNVVTPEEPATQ----PLPVMVFIHGGGYILGSSATPIYDGAALAR
Rv2045c|M.tuberculosis_H37Rv DCLTLNVVTPEEPATQ----PLPVMVFIHGGGYILGSSATPIYDGAALAR
MAV_2466|M.avium_104 DCLTLNVVTPEAPAEG----PLPVMVFIHGGGYFLGSSATPLYDGAALAR
TH_0737|M.thermoresistible__bu DCLTLNVVAPEHPPDS----PMPVLVFIHGGGYLLGSSATPIYDGAALAR
Mvan_3408|M.vanbaalenii_PYR-1 DCLTLNVVAPEGAASAGE--PLPVMFFIHGGGYILGSSATPLYDGAALAR
MSMEG_3848|M.smegmatis_MC2_155 DCLTLNVVAPEKPHDG----PLPVMFFVHGGGYVLGSSATPIYDGAALAR
Mflv_3125|M.gilvum_PYR-GCK DCLTLNVVAPADAEARAADGPLPVMVFIHGGGYLLGSSATPVYDGASLAR
MAB_3453c|M.abscessus_ATCC_199 DCLTVNVVTPDRPSNE----PLPVMFFIYGGGYLLGSSATPLYDGAALAR
****:***:* . *:**:.*::****.*******:****:***
MUL_2261|M.ulcerans_Agy99 RGCVYVSVNYRLGALGCLDLSSLSTPDIAIDGNLYLRDLVMALQWIQDNI
MMAR_3020|M.marinum_M RGCVYVSVNYRLGALGCLDLSSLSTPDIAIDGNLYLRDLVMALQWIQDNI
Mb2071c|M.bovis_AF2122/97 RGCVYVSVNYRLGALGCLDLSSLSTPQITLDSNVYLRDLVLALRWVHDNI
Rv2045c|M.tuberculosis_H37Rv RGCVYVSVNYRLGALGCLDLSSLSTPQITLDSNVYLRDLVLALRWVHDNI
MAV_2466|M.avium_104 RGCVYVSVNYRLGALGCVDFSSLSTPEIPLESNLYLRDLVLALQWVRDNI
TH_0737|M.thermoresistible__bu RGCVYVSVNYRLGALGCMDLSSLSTRRHPIDSNLFLRDLVLALQWVRDNI
Mvan_3408|M.vanbaalenii_PYR-1 RGCVYVSVNYRLGPLGCMDLSSLSTPENPIDDNLFLRDLVMALRWVRDNV
MSMEG_3848|M.smegmatis_MC2_155 RGCVYVSVNYRLGVLGAMELSSLSTPEHPIDDNLFLRDLVLALQWVRDNI
Mflv_3125|M.gilvum_PYR-GCK KGCVYISVNYRLGALGCLELSSLSTPEAPIDDNLFLRDLVMALRWVRDNV
MAB_3453c|M.abscessus_ATCC_199 RGCVYVSVNYRVGALGALDLSSLSDRDHTIDGNLFLRDVVLALQWVHDNI
:****:*****:* **.:::**** .::.*::***:*:**:*::**:
MUL_2261|M.ulcerans_Agy99 AEFGGDPDNVTIFGESAGAHITATLLAVPAAKGLFARAISESPAAGMVRP
MMAR_3020|M.marinum_M AEFGGDPDNVTIFGESAGAHITATLLAVPAAKGLFARAISESPAAGMVRP
Mb2071c|M.bovis_AF2122/97 AEFGGDPGNVTIFGESAGAHITATLLAVPAAKGLFARAISESPAAGMVRS
Rv2045c|M.tuberculosis_H37Rv AEFGGDPGNVTIFGESAGAHITATLLAVPAAKGLFARAISESPAAGMVRS
MAV_2466|M.avium_104 AEFGGDPDNVTIFGESAGACITATLLAVPAAKGLFAQAISESPASGLVRS
TH_0737|M.thermoresistible__bu SVFGGDPGNVTIFGESAGAHAVATLMAVPAAKGLFSQAISQSPASGMVRS
Mvan_3408|M.vanbaalenii_PYR-1 AAFGGDPDKVTIFGESAGAHAVATLLATPQAKGLFAQAISESPASGMVRS
MSMEG_3848|M.smegmatis_MC2_155 AVFGGDPDNVTIFGESAGAHAVATLLAVPAARGLFARVISESPASGMVSS
Mflv_3125|M.gilvum_PYR-GCK AAFGGDPGNVTIFGESAGAHAVSTLVATPEAEGLFAQAIAQSPASGMISD
MAB_3453c|M.abscessus_ATCC_199 GTFGGDPGNVTIFGESAGAHCVETLMATPAAAGLFHRAICQSTASGMAVP
. *****.:********** . **:*.* * *** :.*.:*.*:*:
MUL_2261|M.ulcerans_Agy99 REIAAEFATRFARLLGARKHDAASALMRATAAQLVQTQHRLIDQGMQKRL
MMAR_3020|M.marinum_M REIAAEFATRFARLLGARKHDAASALMRATAAQLVQTQHRLIDQGMQKRL
Mb2071c|M.bovis_AF2122/97 REVAAEFAARFANLIGARTQDAANALMQASPAQLVEAQHHLIRQGMRKRL
Rv2045c|M.tuberculosis_H37Rv REVAAEFAARFANLIGARTQDAANALMQASPAQLVEAQHHLIRQGMRKRL
MAV_2466|M.avium_104 QEVAAEFANRFANLLGVRRQDAANALMQASAAQLVKTQHRLIDEGMQDRL
TH_0737|M.thermoresistible__bu ADVAAEFARRFADLLG-AGRDPAAALMAASPADLVRALDELISRGMTDMP
Mvan_3408|M.vanbaalenii_PYR-1 TEMAAKFASRFADLVANDGGDAAAALMSASPHALIAALDDLVANGFKDMP
MSMEG_3848|M.smegmatis_MC2_155 ADTAARLAGQYAGIIGHGGRDAAEALKTLSPAQLGRALEELINRGMTDMP
Mflv_3125|M.gilvum_PYR-GCK ADIAADYAQRFARQLGADGKDGARALLAARPADLVDALERLIVEGQRDLV
MAB_3453c|M.abscessus_ATCC_199 ADSAAMYAQKFAQILGATTQSAAETVLRSSPAELGAALNMLIADIVTNMP
: ** * ::* :. . * :: . * : . *: .
MUL_2261|M.ulcerans_Agy99 G-AFPIGPTFGDDCLPLDPVEAMRAGQSHKVPLIVGTNADEGRLFTRFLK
MMAR_3020|M.marinum_M G-AFPIGPTFGDDCLPLDPVEAMRAGQSHKVPLIVGTNADEGRLFTRFLK
Mb2071c|M.bovis_AF2122/97 G-AFPIGPVFGDDYLPMDPVEAMRSGRVHAVPLIVGTNAEEGRLFTRFLG
Rv2045c|M.tuberculosis_H37Rv G-AFPIGPVFGDDYLPMDPVEAMRSGRVHAVPLIVGTNAEEGRLFTRFLG
MAV_2466|M.avium_104 G-AFPIGPVVGDDILPTDPVEAMRRGEAHRVPLIVGTNAEEGRLFTRFLA
TH_0737|M.thermoresistible__bu G-AFAVGPSYGDDCLPRHPVEAMRDGRAHDVPLIVGTNAEEGRLFRRFLP
Mvan_3408|M.vanbaalenii_PYR-1 G-AFPVGPTYGTEYLPKDPVEAMRDGTAHRVPLIVGTNAEEGRLFTRFLP
MSMEG_3848|M.smegmatis_MC2_155 G-AFPVGPTYGTEFLPTDPVEAMAAGSAHRVPLIVGNNAEEGRLFTRFLP
Mflv_3125|M.gilvum_PYR-GCK G-AFAIGPTYGTEYLPEDPVEAMRSGRAHPVPLIVGTNADEGRLFTRFLK
MAB_3453c|M.abscessus_ATCC_199 GGSFAIGPCIDGHYLPRHPIEAMEHGEAHRVPLIVGHNADEAKLFTRVLK
* :*.:** . . ** .*:*** * * ****** **:*.:** *.*
MUL_2261|M.ulcerans_Agy99 MLPTNKAMIDELLADTEPATRERITAAYPNYPESAACIQLGGDFAFNAAA
MMAR_3020|M.marinum_M MLPTNKAMIDELLADTEPATRERITAAYPNYPESAACIQLGGDFAFNAAA
Mb2071c|M.bovis_AF2122/97 MLPTNEPMVEELLSGMKPADRERITAAYPNYPAPSACIQLGGDFAFSSAA
Rv2045c|M.tuberculosis_H37Rv MLPTNEPMVEELLSGMKPADRERITAAYPNYPAPSACIQLGGDFAFSSAA
MAV_2466|M.avium_104 MLPTNESMVEELLADAEPAVRERITAAYPDYPDRSACIQLGGDFAFGSAA
TH_0737|M.thermoresistible__bu LLPISEPMIEALFGDTDAEVRDRIIAAYPGYPDADACIRLGGDFAFGTAA
Mvan_3408|M.vanbaalenii_PYR-1 LLPTTEQTIEIMLGDTDAEVRNRIMSAYPDYPKPDACVQIGGDFTFSTAA
MSMEG_3848|M.smegmatis_MC2_155 LLPTNEPMIEKLFADADPEHRERILSAYPGYPDRDVCVRLGGDFAFGSAT
Mflv_3125|M.gilvum_PYR-GCK LLPTNEQAIEQLLSAVEPEARQRVLAAYPKYPAVDACVAFGGDFIFGSAV
MAB_3453c|M.abscessus_ATCC_199 MMPLSESALEGMLARGGPGHRDRIVAAYPGYPERSARVKLAGDMNFSTAA
::* .: :: ::. . *:*: :*** ** . : :.**: *.:*.
MUL_2261|M.ulcerans_Agy99 WQIAEAQGVHAPTYLYRYDYAPRTLRWSGFGATHATELFAVFDIYRTRFG
MMAR_3020|M.marinum_M WQIAEAQGAHAPTYLYRYDYAPRTLRWSGFGATHATELFAVFDIYRTRFG
Mb2071c|M.bovis_AF2122/97 WQIAEAHGANAPTYLYRYDYAPRTLRWSGFGATHATELFAVFDIYRTRFG
Rv2045c|M.tuberculosis_H37Rv WQIAEAHGANAPTYLYRYDYAPRTLRWSGFGATHATELFAVFDIYRTRFG
MAV_2466|M.avium_104 WQIAEAHCAHAPTYLYRYDYAPRTLRWSGFGATHATELLAVFDVYRTRFG
TH_0737|M.thermoresistible__bu WEISEAHSRHAPTYVYRYDYAPRMLHWSGIGATHATELLAVFGTYRTRPG
Mvan_3408|M.vanbaalenii_PYR-1 WQIGEAHSRHAPTFVYRYDYAPRPLHWSGMGATHATELLAVFDIYRTMPG
MSMEG_3848|M.smegmatis_MC2_155 WQVAEAHSRHAPTYVYRYDYAPRALRWSGLGATHAMELLAVFDTYRTRYG
Mflv_3125|M.gilvum_PYR-GCK WQIAHAHSAFAPTYVYRYDYATAALRLSGMGATHATELLAVFDVYRSRFG
MAB_3453c|M.abscessus_ATCC_199 WQMAEAHHRYAPVYFYRYDYAPGALRIAGMGATHATELLAVFDSYRGAMG
*::..*: **.:.******. *: :*:***** **:***. ** *
MUL_2261|M.ulcerans_Agy99 ALLTAAADRRHALRVSDEVIRRWRSFSQTGTPGEDWPAYTHTRRAVMVID
MMAR_3020|M.marinum_M ALLTAAADRRHALRVSDEVIRRWRSFSQTGTPGEDWPAYTHTRRAVMVID
Mb2071c|M.bovis_AF2122/97 ALLTAAADRRAALRVSNEVQRRWRCFSQIGVPGDDWPAYTQDDRAVLVFD
Rv2045c|M.tuberculosis_H37Rv ALLTAAADRRAALRVSNEVQRRWRCFSQIGVPGDDWPAYTQDDRAVLVFD
MAV_2466|M.avium_104 ALLTAAADRRAALRVSNQVQRRWRAFSRTGVPGEDWPRYTAADRAVLVFD
TH_0737|M.thermoresistible__bu RLLTLAGDWVSAQRVSSDLQRRWLAFGRTGVPGDDWPAYTAEHRPVRVFD
Mvan_3408|M.vanbaalenii_PYR-1 ALLTLAGDWRSARRVSKDVQRRWSSFSRTGVPGADWPRYSAEDRPVMVFD
MSMEG_3848|M.smegmatis_MC2_155 SMLTAMADRRSARRVSRDIQTRWRDFSRAGVPGDGWPAYRHDERAVYVFD
Mflv_3125|M.gilvum_PYR-GCK KLLAAGLDSRSAKKVTDDVQKRWLGFAERAVPGGDWPQYTRDERAVLVLD
MAB_3453c|M.abscessus_ATCC_199 TVMAGALGRRDAVRVSNDVQRRWLAFARSGVPGDGWPTYGPPDRAVMVFD
::: . * :*: :: ** *.. ..** .** * *.* *:*
MUL_2261|M.ulcerans_Agy99 RKSRVEIDPHRHRRLAWDGFSLAR----
MMAR_3020|M.marinum_M RKSRVEIDPHQHRRLAWDGFSLAR----
Mb2071c|M.bovis_AF2122/97 RRCRIEFDPHQHRRIAWDGFSLAN----
Rv2045c|M.tuberculosis_H37Rv RRCRIEFDPHQHRRIAWDGFSLAN----
MAV_2466|M.avium_104 RKSRVEFDPHPHRRMAWDGFSLAR----
TH_0737|M.thermoresistible__bu RNPRVEYDPDAHRRQAWQGFTLTRPDRN
Mvan_3408|M.vanbaalenii_PYR-1 RHPRLEYDPHAHRRQAWEGFSLA-----
MSMEG_3848|M.smegmatis_MC2_155 TRPRVEYDPDADRRLAWEGFSLAQR---
Mflv_3125|M.gilvum_PYR-GCK RRRRVEFDPHSERRQAWEGFFLATR---
MAB_3453c|M.abscessus_ATCC_199 HATRVELDPEAARRAAWEGFSLTL----
*:* **. ** **:** *: