For questions or suggestions e-mail us at: ioerger@cs.tamu.edu

M. thermoresistible (build 8) TH_3935 (-)

annotation: putative acyl-CoA dehydrogenase domain protein
coordinates: 2975768 - 2976970
length: 401

aa seq not available

Operon Prediction Model: Genebank

Paralogs
speciesidgenee-valueidentity (len)annotation
M. thermoresistible (build 8)TH_3935--100% (401)putative acyl-CoA dehydrogenase domain protein
M. thermoresistible (build 8)TH_3515-1e-6740.97% (393) PUTATIVE acyl-CoA dehydrogenase domain protein
M. thermoresistible (build 8)TH_4263-5e-6140.10% (394) PUTATIVE acyl-CoA dehydrogenase domain protein

Closest Orthologs (e-value cutoff: 1e-4)
speciesidgenee-valueidentity (len)annotation
M. bovis AF2122 / 97Mb3590cfadE301e-6341.67% (396) acyl-CoA dehydrogenase FADE30
M. gilvum PYR-GCKMflv_1794-1e-6842.32% (397) acyl-CoA dehydrogenase domain-containing protein
M. tuberculosis H37RvRv3560cfadE301e-6341.67% (396) acyl-CoA dehydrogenase FADE30
M. leprae Br4923MLBr_00737fadE253e-3029.72% (387) putative acyl-CoA dehydrogenase
M. abscessus ATCC 19977MAB_0597-2e-5838.82% (389) acyl-CoA dehydrogenase FadE
M. marinum MMMAR_4992fadE266e-6236.92% (390) acyl-CoA dehydrogenase FadE26
M. avium 104MAV_0601-2e-6240.61% (394) putative acyl-CoA dehydrogenase
M. smegmatis MC2 155MSMEG_5619-1e-6540.60% (399) acyl-CoA dehydrogenase domain-containing protein
M. ulcerans Agy99MUL_4067fadE262e-6036.41% (390) acyl-CoA dehydrogenase FadE26
M. vanbaalenii PYR-1Mvan_4956-8e-6942.61% (399) acyl-CoA dehydrogenase domain-containing protein

CLUSTAL 2.0.9 multiple sequence alignment


Mb3590c|M.bovis_AF2122/97           --------------MQDV-------------EEFRAQVRGWLADNLAGEF
Rv3560c|M.tuberculosis_H37Rv        --------------MQDV-------------EEFRAQVRGWLADNLAGEF
MAV_0601|M.avium_104                --------------MQDV-------------EEFRAEVRSWLADNLVGEF
MAB_0597|M.abscessus_ATCC_1997      MVESQVSPAPAGEPMSEMSD-----------DQVRTEIREWLAENLVGEF
Mflv_1794|M.gilvum_PYR-GCK          --------------MSELET-------------FRAEVRDWCREHVPADW
Mvan_4956|M.vanbaalenii_PYR-1       -------------MTAESEDQRDNPTDSQSQAQFRQQVRAWCRDHIPADW
MSMEG_5619|M.smegmatis_MC2_155      --------------MTHPEN----------LDDFRATVRDWCAAHVPKDW
TH_3935|M.thermoresistible__bu      ------------MPLTPIVRFG----GAEHVEQLRASVRSWLADNLPDEF
MMAR_4992|M.marinum_M               ------------MRISYTPE----------QEELRRELRSYFTTLMTPER
MUL_4067|M.ulcerans_Agy99           ------------MRISYTPE----------QEELRRELRSYFTTLMTPER
MLBr_00737|M.leprae_Br4923          -------------MVGWSGN--------PLFDLFKLPEEHNELRATIRAL
                                                                     .:   .           

Mb3590c|M.bovis_AF2122/97           AALKGLGGPGREHEAFEERRAWNQRLAAAGLTCLGWPEEHGGRGLSTAHR
Rv3560c|M.tuberculosis_H37Rv        AALKGLGGPGREHEAFEERRAWNQRLAAAGLTCLGWPEEHGGRGLSTAHR
MAV_0601|M.avium_104                AALKGLGGPGREHEAFEERRAWNQHLAKAGLTCLGWPVEHGGRGLSTAHR
MAB_0597|M.abscessus_ATCC_1997      AELKGLGGPGSEHEAFEERLAWNRHLAAAGWTCLGWPVEHGGRGATVSQR
Mflv_1794|M.gilvum_PYR-GCK          RAAQ-SGVGEEEFVRFQK--AWFAELHSAGYAVPHWPAQWGG-GLPVDKQ
Mvan_4956|M.vanbaalenii_PYR-1       RDTQ-TGVGDEEFVRFQK--AWFAELHSAGYAVPHWPAEWGG-GLPVDRQ
MSMEG_5619|M.smegmatis_MC2_155      RAAQ-TGVSDDEFAAFQK--AWFAELHSAGYAVPHWPAEWGG-GMSVPQQ
TH_3935|M.thermoresistible__bu      RRTA-ANPDYLPREGHERAVRFCRELHAQGWFVPHWPAKFEGGGLGVVEQ
MMAR_4992|M.marinum_M               REALSSVQG--EYGTGNVYRETVAQMGKDGWLTLNWPKEYGGQDRSPMDS
MUL_4067|M.ulcerans_Agy99           REALSSVQG--EYGTGNVYRETVAQMGKNGWLTLNWPKEYGGQDRSPMDS
MLBr_00737|M.leprae_Br4923          AEKEIAPHAADVDQRARFPEEALAALNASGFNAIHVPEEYGGQGADSVAA
                                                    .        :   *      * :  * .      

Mb3590c|M.bovis_AF2122/97           VAFYEEYARADAPDKVN-HFGEELLGPTLIAFGTPQQQRRFLPRIRDVTE
Rv3560c|M.tuberculosis_H37Rv        VAFYEEYARADAPDKVN-HFGEELLGPTLIAFGTPQQQRRFLPRIRDVTE
MAV_0601|M.avium_104                VAFYEEYARADAPDKVN-HFGEELLGPTLIAFGTPEQQQRFLPRILDVTE
MAB_0597|M.abscessus_ATCC_1997      VIFYEEYARAEAPHKVN-HLGEELLGPTLIAYGTPEQQQRFLPAIRDVTE
Mflv_1794|M.gilvum_PYR-GCK          VVLYQELAAHDAPRLVLAFVGIHHAASTLLVAGTEEQRRRHLPAILDG-E
Mvan_4956|M.vanbaalenii_PYR-1       VVLYQELAAHDAPRLVLAFVGIHHAASTLLVAGTDEQRRRHLPAILDG-E
MSMEG_5619|M.smegmatis_MC2_155      IVLYSELAAHDAPRLVLAFVGIHHAASTLLAAGTDAQRNRHLPAILDG-E
TH_3935|M.thermoresistible__bu      VVIREELAYAGAP-LVN-TNGVNMLAPVLFRFGTPEQQQEHLPLIARSER
MMAR_4992|M.marinum_M               LIFTDEAAIAGAP---VPFLTINSVAPTIMAFGTDEQKKFFLPKIAAGDL
MUL_4067|M.ulcerans_Agy99           LIFTDEAAIAGAP---VPFLTINSVAPTIMAFGTDEQKKFFLPKIAAGDL
MLBr_00737|M.leprae_Br4923          CIVIEEVARVDASASLIPAVNKLGTMG-LILRGSEELKKQVLPSLAAEGA
                                      . .* *   *.               ::  *:   :.  ** :     

Mb3590c|M.bovis_AF2122/97           LWCQGYSEPGAGSDLASVATTAELDGDQWVINGQKVWTSLAHLSQWCFVL
Rv3560c|M.tuberculosis_H37Rv        LWCQGYSEPGAGSDLASVATTAELDGDQWVINGQKVWTSLAHLSQWCFVL
MAV_0601|M.avium_104                LWCQGYSEPGAGSDLANVSTTAELDGDQWVINGQKVWTSLAHLSQWCFVV
MAB_0597|M.abscessus_ATCC_1997      LWCQGYSEPGAGSDLANVSTSAVLDGGDWVINGQKVWTSLALQSQWCFVV
Mflv_1794|M.gilvum_PYR-GCK          IWVQGFSEPEAGSDLAALRTSARRVGDEFIVNGQKLWASGGMHADWCLLL
Mvan_4956|M.vanbaalenii_PYR-1       IWVQGFSEPEAGSDLAALRTTARRAGDEFVVNGQKLWASGGMHADWCLLL
MSMEG_5619|M.smegmatis_MC2_155      IWVQGFSEPEAGSDLASLRTTARAEGDTFVVNGQKLWASGAMYADWCLLL
TH_3935|M.thermoresistible__bu      MWAQGYSEPEAGSDLASLRMTARRDGDHYVLNGQKTWTSNGVLADWIFVL
MMAR_4992|M.marinum_M               HFSIGYSEPGAGTDLANLRTTAVRDGDDYVINGQKMWTSLIAYADWVWLA
MUL_4067|M.ulcerans_Agy99           HFSIGYSEPGAGTDLANLRTTAVRDGDDYLINGQKMWTSLIAYADWVCLA
MLBr_00737|M.leprae_Br4923          MASYALSEREAGSDAASMRTRAKADGDDWILNGFKCWITNGGKSTWYTVM
                                        . **  **:* * :   *   *. :::** * * :    : *  : 

Mb3590c|M.bovis_AF2122/97           ARTEKGSQRH------AGLSYLLVPLDQPGVQIRPIVQITGT--AEFNEV
Rv3560c|M.tuberculosis_H37Rv        ARTEKGSQRH------AGLSYLLVPLDQPGVQIRPIVQITGT--AEFNEV
MAV_0601|M.avium_104                ARTEKGSKRH------AGLSYLLVPLDQPGVQIRPIVQITGT--AEFNEV
MAB_0597|M.abscessus_ATCC_1997      ARTEPGSSRH------KGLSYLLVPLDQPGVEIRPIIQLTGT--SEFNEV
Mflv_1794|M.gilvum_PYR-GCK          ARTDPDAPKR------KGISYFLLDMTSPGVDVRPIRNAIGD--SHFCEI
Mvan_4956|M.vanbaalenii_PYR-1       ARTDPDAPKRPGARKSAGISYFLMDMTTPGVDVRPIRNAIGD--SHFCEI
MSMEG_5619|M.smegmatis_MC2_155      ARTDPNAPKR------HGISYFMMDMKTPGVDVRPIRNAVGD--SHFCEI
TH_3935|M.thermoresistible__bu      ARTSPVSGKR-----QQGISFFLVDLSSPGITRRPIRSMTGY--PTFAEE
MMAR_4992|M.marinum_M               VRTNPEAKKH------RGISMLVVPTTAEGFSWTPVHTMAG---PDTSAT
MUL_4067|M.ulcerans_Agy99           VRTNPEAKKH------RGISMLVVPTTAEGFSWTPVHTMAG---PDTSAT
MLBr_00737|M.leprae_Br4923          AVTDPDKGAN-------GISAFIVHKDDEGFSIGPKEKKLGIKGSPTTEL
                                    . *.     .       *:* :::     *.   *     *   .     

Mb3590c|M.bovis_AF2122/97           FFDDARTDADLVVGAPGDGWRVAMATLTFERG-VSTLGQQIVYARELSNL
Rv3560c|M.tuberculosis_H37Rv        FFDDARTDADLVVGAPGDGWRVAMATLTFERG-VSTLGQQIVYARELSNL
MAV_0601|M.avium_104                FFDDARTDASMVVGQPGDGWRVAMGTLTFERG-VSTLGQQIRYARELSNL
MAB_0597|M.abscessus_ATCC_1997      FFDNARTSADLVVGEPGDGWRVAMGTLTFERG-VSTLGNQITYARELSRL
Mflv_1794|M.gilvum_PYR-GCK          FLDDVRIPATNLIGAENAGWQVAQETLGAERG-MTMLELAERLG--NAGF
Mvan_4956|M.vanbaalenii_PYR-1       FLDDVRIPAANLIGAENNGWQVAQATLGAERG-LTMLELAERLG--NAGF
MSMEG_5619|M.smegmatis_MC2_155      FLNDVVIPSANLVGPVNKGWQVAQATLGAERG-MTMLELAERLG--NAGF
TH_3935|M.thermoresistible__bu      FFDDVRVPAKNLVGAEGDGWKVAKALLNAERSNVTRAAQAQRFLDELVDW
MMAR_4992|M.marinum_M               YYTDVRVPVTNLIGEENAGWKLVTNQLNHERVALVSSAPISMALREVREW
MUL_4067|M.ulcerans_Agy99           YYTDVRVPVTNLIGEENAGWKLVTNQLNHERVALVSSAPISMALREVREW
MLBr_00737|M.leprae_Br4923          YFDKCRIPGDRIIGEPGTGFKTALATLDHTRPTIGAQAVGIAQGALDAAI
                                    :  .       ::*  . *:: .   *   *  :                

Mb3590c|M.bovis_AF2122/97           VELARRT----AAADDPLIRERLTRAWTGLRAMRSYALATMEGP--AVEQ
Rv3560c|M.tuberculosis_H37Rv        VELARRT----AAADDPLIRERLTRAWTGLRAMRSYALATMEGP--AVEQ
MAV_0601|M.avium_104                AELARRN----GAADDPFIRERLTRAWTGLRAMRSYALATMD-----VEQ
MAB_0597|M.abscessus_ATCC_1997      AELAKSN----GAADDPAIRERLAQAYVGMRTMRAYALATMD-----EER
Mflv_1794|M.gilvum_PYR-GCK          RWLVES-----APVDDPIVADRLAGFETELAALRGMCRRMVEH---GPSG
Mvan_4956|M.vanbaalenii_PYR-1       RWLVQS-----APVDDPIVADRLAGFETEITGLRGLCRQIVER---GATG
MSMEG_5619|M.smegmatis_MC2_155      RWLVDAC----SPVDDPVVADRLAQFEIELTGLRGLCRDLVERSETGEAG
TH_3935|M.thermoresistible__bu      CHAQRGKP--HDPLADPTNRLALARAVERVEVGRILSYRIAHLQAAGSLD
MMAR_4992|M.marinum_M               AQNTKDAGG-ARLIDSEWVQLNLARVHAKVEVLKLINWELASN--DAAPS
MUL_4067|M.ulcerans_Agy99           AQNTKDAGG-ARLIDSEWVQLNLARVHAKVEVLKLINWELASN--DAAPS
MLBr_00737|M.leprae_Br4923          VYTKDRKQFGESISTFQSIQFMLADMAMKVEAARLIVYAAAARAERGEPD
                                                          *:     :   :                

Mb3590c|M.bovis_AF2122/97           PGQD-NVSKLLWANWHRNLGELAMDVIGKPGMTMPDG------EFDEWQR
Rv3560c|M.tuberculosis_H37Rv        PGQD-NVSKLLWANWHRNLGELAMDVIGKPGMTMPDG------EFDEWQR
MAV_0601|M.avium_104                PGQD-NVSKLLWANWHRALGELAMDVIGKPGMTMPDG------EFDEWQR
MAB_0597|M.abscessus_ATCC_1997      PGQD-NVSKLLWANWHRDLGELAMEIIGTSTLLTNAG------EMDEWQR
Mflv_1794|M.gilvum_PYR-GCK          PADP-SVVKLYYSELLQRLTDFGAEIGGLPAHTVLTKPMSSGWESGSWVL
Mvan_4956|M.vanbaalenii_PYR-1       PADA-SVVKLYYSELLQRLTDFAVEIGGPEAHTVLAKPMSSGWESGSWVL
MSMEG_5619|M.smegmatis_MC2_155      PADA-SIVKLYYSELLQRMTDFGAQIAGLPAHTVLTKPASSGWESGAWML
TH_3935|M.thermoresistible__bu      PTLP-SLSKLYHSELTAELRALGAQILGPAGALMPDDP--EAVLHGHFSD
MMAR_4992|M.marinum_M               PADA-SAAKVFGTELATEAYRLLMEVLGTAATLRQDSP--GALLHGRVER
MUL_4067|M.ulcerans_Agy99           PADA-SAAKVFGTELATEAYRLLMEVLGTAATLRQDSP--GALLRGRVER
MLBr_00737|M.leprae_Br4923          LGFISAASKCFASDIAMEVTTDAVQLFGGAGYTSDFP----------VER
                                            *   ::          :: *                      

Mb3590c|M.bovis_AF2122/97           LYLFTRADTIYGGSNEIQRNIIAERVLGLPREAKG-
Rv3560c|M.tuberculosis_H37Rv        LYLFTRADTIYGGSNEIQRNIIAERVLGLPREAKG-
MAV_0601|M.avium_104                LFLFTRADTIYGGSNEIQRNIIAERVLGLPREVKG-
MAB_0597|M.abscessus_ATCC_1997      LFLFSRADTIYGGSNEIQRNIISERVLGLPREAR--
Mflv_1794|M.gilvum_PYR-GCK          DFVGSWEWTIPGGASEIQRTIIGERGLGLPREPSAL
Mvan_4956|M.vanbaalenii_PYR-1       DFVGSWEWTIPGGASEIQRTIIAERGLGLPREPGAA
MSMEG_5619|M.smegmatis_MC2_155      DFIGSWEWTIPGGASEIQRTIIGERGLGLPREPSAV
TH_3935|M.thermoresistible__bu      GLLLSLLHTIGGGTSEIQRDLISTSGLGLPR-----
MMAR_4992|M.marinum_M               MHRACLILTFGGGTNEVQRDIIGMVALGLPRANR--
MUL_4067|M.ulcerans_Agy99           MHRACLILTFGGGTNEVQRDIIGMVALGLPRANR--
MLBr_00737|M.leprae_Br4923          FMRDAKITQIYEGTNQIQRVVMSRALLR--------
                                             :  *:.::** ::.   *