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M. thermoresistible (build 8) TH_3507 (-)

annotation: putative nitroreductase
coordinates: 653615 - 654265
length: 217

aa seq not available

Operon Prediction Model: Genebank

Paralogs
speciesidgenee-valueidentity (len)annotation
M. thermoresistible (build 8)TH_3507--100% (217)putative nitroreductase
M. thermoresistible (build 8)TH_2448-1e-2434.27% (213) PUTATIVE nitroreductase
M. thermoresistible (build 8)TH_4633-4e-1931.43% (210) PUTATIVE putative nitroreductase

Closest Orthologs (e-value cutoff: 1e-4)
speciesidgenee-valueidentity (len)annotation
M. bovis AF2122 / 97Mb3403c-1e-2137.89% (190) oxidoreductase
M. gilvum PYR-GCKMflv_2149-2e-3441.20% (216) nitroreductase
M. tuberculosis H37RvRv3368c-1e-2137.89% (190) oxidoreductase
M. leprae Br4923MLBr_00418-3e-1835.45% (189) putative oxidoreductase
M. abscessus ATCC 19977MAB_4760-3e-1842.98% (121) nitroreductase
M. marinum MMMAR_1160-9e-2036.17% (188) nitroreductase
M. avium 104MAV_4334-5e-2138.42% (190) nitroreductase family protein
M. smegmatis MC2 155MSMEG_5155-2e-3640.65% (214) nitroreductase
M. ulcerans Agy99MUL_2854-1e-2036.70% (188) nitroreductase
M. vanbaalenii PYR-1Mvan_4554-5e-3339.63% (217) nitroreductase

CLUSTAL 2.0.9 multiple sequence alignment


MLBr_00418|M.leprae_Br4923          ------MSVDEVLTTTRSVRKRLDFDKPVPRDVLMECLQLALQAPTGSNS
MAV_4334|M.avium_104                --MTLNLSVDEVLTTTRSVRKRLDFDKPVPREVLMECLELALQAPTGSNA
Mb3403c|M.bovis_AF2122/97           --MTLNLSVDEVLTTTRSVRKRLDFDKPVPRDVLMECLELALQAPTGSNS
Rv3368c|M.tuberculosis_H37Rv        --MTLNLSVDEVLTTTRSVRKRLDFDKPVPRDVLMECLELALQAPTGSNS
MMAR_1160|M.marinum_M               --MTLNLSVDEVLTTTRSVRKRLDFDKPVSREVLMECLDLALQAPTGSNS
MUL_2854|M.ulcerans_Agy99           --MTLNLSVDEVLTTTRSVRKRLDFDKPVSREVLMECLDLALQAPTGSNS
Mflv_2149|M.gilvum_PYR-GCK          MRQDLNMDLYDVMRTTGAVRQFT--GDPLPDDVLRRILDHARFAPSGGNR
Mvan_4554|M.vanbaalenii_PYR-1       ------MDLYDVMRTTGAVRQFT--GDPLPDEVLVRILDNARFAPSGGNR
MSMEG_5155|M.smegmatis_MC2_155      ------MEFTDVVRTTAAIRQFT--GDPLPDDVLRRILDNARFAPSGGNR
MAB_4760|M.abscessus_ATCC_1997      --------------------------------------------------
TH_3507|M.thermoresistible__bu      ------VELVEAMRTTGTCRYFR--PDPVPDEVLYQAFDHARFAPQGGNR
                                                                                      

MLBr_00418|M.leprae_Br4923          QGWHWVFVEDAEKRKAIGDIYLVNARCYLSQPAPEYPEGDTRGERMR---
MAV_4334|M.avium_104                QGWQWVFVEDADKKKAIADIYLANARAYLSLPAAEYPEGDTRGERMP---
Mb3403c|M.bovis_AF2122/97           QGWQWVFVEDAAKKKAIADVYLANARGYLSGPAPEYPDGDTRGERMG---
Rv3368c|M.tuberculosis_H37Rv        QGWQWVFVEDAAKKKAIADVYLANARGYLSGPAPEYPDGDTRGERMG---
MMAR_1160|M.marinum_M               QGWQWVFVEDADKKKAIAEVYLARARSYLSMPAPEYAEGDTRGERMG---
MUL_2854|M.ulcerans_Agy99           QGWQWVFVEDADKKKAIADVYLARARSYLSMPAPEYAEGDTRGERMG---
Mflv_2149|M.gilvum_PYR-GCK          QGVHVIAVRDVATRRALAELSRTGARRYLAQKHNGEGPWNPLRPMKVTAD
Mvan_4554|M.vanbaalenii_PYR-1       QGVHVIAVRDRATREALGALSVTGARRYIAQQRNGEGPWNPLRPMQISAE
MSMEG_5155|M.smegmatis_MC2_155      QGTRVVVIRDRDTREALAELTITGSRRYIAQKRIGENPWNPLHPTAVTEA
MAB_4760|M.abscessus_ATCC_1997      --------------------------------------------------
TH_3507|M.thermoresistible__bu      QPVRWIVVRDPARKAALQDLYLPLWKNYLSGIADGTVNVGALP-------
                                                                                      

MLBr_00418|M.leprae_Br4923          --LVRDSATYLAEHMHEVPVLLIPCLL----GRAEESPLG-AVSYWASLF
MAV_4334|M.avium_104                --KVKDSAVYLAEHMHEAPVLLIPCLE----GRVENAPLGLSASFWASLF
Mb3403c|M.bovis_AF2122/97           --RVRDSATYLAEHMHRAPVLLIPCLK----GREDESAVG-GVSFWASLF
Rv3368c|M.tuberculosis_H37Rv        --RVRDSATYLAEHMHRAPVLLIPCLK----GREDESAVG-GVSFWASLF
MMAR_1160|M.marinum_M               --KVRDSATYLAEHMHEAPVLMIPCIQ----GREDKSPLG-GVSFWASLF
MUL_2854|M.ulcerans_Agy99           --KVRDSATYLAEHMHEAPVLMIPCIQ----GREDKSPLG-GVSLWASLF
Mflv_2149|M.gilvum_PYR-GCK          EVAAIEVPEQMTAPLLTAAVVLVFSVDLDVVAAIDQDLDRIGLVAGASVY
Mvan_4554|M.vanbaalenii_PYR-1       QLAATEVPAELSAPLLTSAVVLVVCVDLAVVAAFDQDLDRVGLIAGASAY
MSMEG_5155|M.smegmatis_MC2_155      DLAAVDVPR--ATPLLDAAVVLVVCVDLGVVAAFDQDLDRIGVVSGASVY
MAB_4760|M.abscessus_ATCC_1997      -----MVPESVAAPLRTAGAVLVVCVDLRLVAAVDQDLERVGVVGGASIY
TH_3507|M.thermoresistible__bu      --KTVRDADYFAEHLAEAPAIVVACAELDGLHPTDTDLGRLSIVGGASVY
                                           .   :  :    .::: .         :      .    ** :

MLBr_00418|M.leprae_Br4923          PAVWSFCLALRSRGLGTCWTSLHLLGDGEQRAAEVLGIPSDKYSQGGLFP
MAV_4334|M.avium_104                PAAWSFCLALRSRGLGTCWTTLHLINDGEKQAAELLGIPHDRYSQGGLFP
Mb3403c|M.bovis_AF2122/97           PAVWSFCLALRSRGLGSCWTTLHLLDNGEHKVADVLGIPYDEYSQGGLLP
Rv3368c|M.tuberculosis_H37Rv        PAVWSFCLALRSRGLGSCWTTLHLLDNGEHKVADVLGIPYDEYSQGGLLP
MMAR_1160|M.marinum_M               PAVWSFCLALRSRGLGSCWTTLHLLADGERQVADVLGIPYDDYSQGGLFP
MUL_2854|M.ulcerans_Agy99           PAVWSFCLALRSRGLGSCWTTLHLLADGERQVADVLGIPYDDYSQGGLFP
Mflv_2149|M.gilvum_PYR-GCK          PFVWNVLLAARNEGFGGVLTTMAVAE--EPRVKELLGLP-DEHAVAAIVP
Mvan_4554|M.vanbaalenii_PYR-1       PFVWNVLLAARNEGFGGVLTTMAVAE--EPGVKALLGIP-DDHAVAAVLP
MSMEG_5155|M.smegmatis_MC2_155      PFVWNILLSARNEGFGGVLTTMAIAE--EPKVKELLAIP-DDYAVAAVLP
MAB_4760|M.abscessus_ATCC_1997      PLVWNILLAARAEGYGGALTTMAVAE--EPKVRELLGIP-DTYAVAAVLP
TH_3507|M.thermoresistible__bu      PTVQNFCLALRNLGVGSALTTLLCQV--EPEVRELLAIP-EGVATAAHIA
                                    * . .. *: *  * *   *::      *  .  :*.:* :  : .. ..

MLBr_00418|M.leprae_Br4923          IAYTKGTDFRPANRLPAENVTHWDIW-----------------------
MAV_4334|M.avium_104                IAYTKGTDFRPAKRLPAEQVTHWDSW-----------------------
Mb3403c|M.bovis_AF2122/97           IAYTQGIDFRPAKRLPAESVTHWNGW-----------------------
Rv3368c|M.tuberculosis_H37Rv        IAYTQGIDFRPAKRLPAESVTHWNGW-----------------------
MMAR_1160|M.marinum_M               IAYTKGTDFRPAKRLPADRLTHWNSW-----------------------
MUL_2854|M.ulcerans_Agy99           IAYTKGTDFRPAKRLPADRLTHWNSW-----------------------
Mflv_2149|M.gilvum_PYR-GCK          MGRPLR-QVTKLTRRPVAEFATRENFDGESL------------------
Mvan_4554|M.vanbaalenii_PYR-1       LGRPQR-QVTKLTRRPVSQFATRERFDGESL------------------
MSMEG_5155|M.smegmatis_MC2_155      LGKPVH-QPTKLTRKPVSEIATRERFDGAPF------------------
MAB_4760|M.abscessus_ATCC_1997      IGKPVK-QLTRLRRNRAAEFVTRERFDGPPWRTTTGEHHSESPRYPRSH
TH_3507|M.thermoresistible__bu      IGYPRDPFPAKLTRLPVEDVVAAETYDQPFFAPTTV-------------
                                    :. .         *  .  ..  : :