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VVPESVAAPLRTAGAVLVVCVDLRLVAAVDQDLERVGVVGGASIYPLVWNILLAARAEGYGGALTTMAVA EEPKVRELLGIPDTYAVAAVLPIGKPVKQLTRLRRNRAAEFVTRERFDGPPWRTTTGEHHSESPRYPRSH
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. abscessus ATCC 19977 | MAB_4760 | - | - | 100% (140) | nitroreductase |
| M. abscessus ATCC 19977 | MAB_3693c | - | 3e-06 | 32.61% (92) | oxidoreductase |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb3403c | - | 4e-07 | 33.96% (106) | oxidoreductase |
| M. gilvum PYR-GCK | Mflv_2149 | - | 3e-43 | 66.10% (118) | nitroreductase |
| M. tuberculosis H37Rv | Rv3368c | - | 4e-07 | 33.96% (106) | oxidoreductase |
| M. leprae Br4923 | MLBr_00418 | - | 8e-05 | 38.18% (55) | putative oxidoreductase |
| M. marinum M | MMAR_2938 | - | 2e-09 | 38.27% (81) | nitroreductase |
| M. avium 104 | MAV_1266 | - | 9e-13 | 40.74% (81) | nitroreductase family protein |
| M. smegmatis MC2 155 | MSMEG_5155 | - | 5e-43 | 70.69% (116) | nitroreductase |
| M. thermoresistible (build 8) | TH_3507 | - | 1e-18 | 42.98% (121) | PUTATIVE putative nitroreductase |
| M. ulcerans Agy99 | MUL_2198 | - | 6e-10 | 38.27% (81) | nitroreductase |
| M. vanbaalenii PYR-1 | Mvan_4554 | - | 2e-42 | 66.95% (118) | nitroreductase |
CLUSTAL 2.0.9 multiple sequence alignment
Mflv_2149|M.gilvum_PYR-GCK MRQDLNMDLYDVMRTTGAVRQFT--GDPLPDDVLRRILDHARFAPSGGNR
Mvan_4554|M.vanbaalenii_PYR-1 ------MDLYDVMRTTGAVRQFT--GDPLPDEVLVRILDNARFAPSGGNR
MSMEG_5155|M.smegmatis_MC2_155 ------MEFTDVVRTTAAIRQFT--GDPLPDDVLRRILDNARFAPSGGNR
MAB_4760|M.abscessus_ATCC_1997 --------------------------------------------------
TH_3507|M.thermoresistible__bu ------VELVEAMRTTGTCRYFR--PDPVPDEVLYQAFDHARFAPQGGNR
MMAR_2938|M.marinum_M ------MPLEDAMRTQRSIRRLK--SDPVDDSLVLHLLELAMKAPTGSNA
MUL_2198|M.ulcerans_Agy99 ------MPLEDAMRTQRSIRRLK--SDPVDDSLVLHLLELAMKAPTGSNA
Mb3403c|M.bovis_AF2122/97 --MTLNLSVDEVLTTTRSVRKRLDFDKPVPRDVLMECLELALQAPTGSNS
Rv3368c|M.tuberculosis_H37Rv --MTLNLSVDEVLTTTRSVRKRLDFDKPVPRDVLMECLELALQAPTGSNS
MLBr_00418|M.leprae_Br4923 ------MSVDEVLTTTRSVRKRLDFDKPVPRDVLMECLQLALQAPTGSNS
MAV_1266|M.avium_104 ------MNVEYLLTATPSARKSLDLDAPVEPGDIRECLRIGLQAANGSNA
Mflv_2149|M.gilvum_PYR-GCK QGVHVIAVRDVATRRALAELSRTGARRYLAQKHNGEGPWNPLRPMKVTAD
Mvan_4554|M.vanbaalenii_PYR-1 QGVHVIAVRDRATREALGALSVTGARRYIAQQRNGEGPWNPLRPMQISAE
MSMEG_5155|M.smegmatis_MC2_155 QGTRVVVIRDRDTREALAELTITGSRRYIAQKRIGENPWNPLHPTAVTEA
MAB_4760|M.abscessus_ATCC_1997 --------------------------------------------------
TH_3507|M.thermoresistible__bu QPVRWIVVRDPARKAALQDLYLPLWKNYLSGIADGTVNVGALP-------
MMAR_2938|M.marinum_M QNWEFIVVKDREVVAKLGRLNRRAMQLFGPIYRRSIARRGDEK-------
MUL_2198|M.ulcerans_Agy99 QNWEFIVVKDREVVAKLGRLNRRAMQLFGPIYRRSIARRGDEK-------
Mb3403c|M.bovis_AF2122/97 QGWQWVFVEDAAKKKAIADVYLANARGYLSGPAPEYPDGDT-RGERMG--
Rv3368c|M.tuberculosis_H37Rv QGWQWVFVEDAAKKKAIADVYLANARGYLSGPAPEYPDGDT-RGERMG--
MLBr_00418|M.leprae_Br4923 QGWHWVFVEDAEKRKAIGDIYLVNARCYLSQPAPEYPEGDT-RGERMR--
MAV_1266|M.avium_104 QSWRWLVVSDPALRARIAELYRD---AYLRRVGGRLLAGLMPAGTPES--
Mflv_2149|M.gilvum_PYR-GCK EVAAIEVPEQMTAPLLTAAVVLVFSVDLDVVAAIDQDLDRIGLVAGASVY
Mvan_4554|M.vanbaalenii_PYR-1 QLAATEVPAELSAPLLTSAVVLVVCVDLAVVAAFDQDLDRVGLIAGASAY
MSMEG_5155|M.smegmatis_MC2_155 DLAAVDVPR--ATPLLDAAVVLVVCVDLGVVAAFDQDLDRIGVVSGASVY
MAB_4760|M.abscessus_ATCC_1997 -----MVPESVAAPLRTAGAVLVVCVDLRLVAAVDQDLERVGVVGGASIY
TH_3507|M.thermoresistible__bu --KTVRDADYFAEHLAEAPAIVVACAELDGLHPTDTDLGRLSIVGGASVY
MMAR_2938|M.marinum_M MLRLQKAVQWQADHFEEIPVVVVACLRG--VIAPWPRISTSSAYG--SIY
MUL_2198|M.ulcerans_Agy99 MLRLQKAVQWQADHFEEIPVVVVACLRG--VIAPWPRISTSSAYG--SIY
Mb3403c|M.bovis_AF2122/97 --RVRDSATYLAEHMHRAPVLLIPCLK----GRED-ESAVGGVSFWASLF
Rv3368c|M.tuberculosis_H37Rv --RVRDSATYLAEHMHRAPVLLIPCLK----GRED-ESAVGGVSFWASLF
MLBr_00418|M.leprae_Br4923 --LVRDSATYLAEHMHEVPVLLIPCLL----GRAE-ESPLGAVSYWASLF
MAV_1266|M.avium_104 --RIMSSTEWLVENLARVPMLVIPCYEP-YLPRIDGDESFHLATLYGSIF
: ::: . * :
Mflv_2149|M.gilvum_PYR-GCK PFVWNVLLAARNEGFGGVLTTMAVAE--EPRVKELLGLP-DEHAVAAIVP
Mvan_4554|M.vanbaalenii_PYR-1 PFVWNVLLAARNEGFGGVLTTMAVAE--EPGVKALLGIP-DDHAVAAVLP
MSMEG_5155|M.smegmatis_MC2_155 PFVWNILLSARNEGFGGVLTTMAIAE--EPKVKELLAIP-DDYAVAAVLP
MAB_4760|M.abscessus_ATCC_1997 PLVWNILLAARAEGYGGALTTMAVAE--EPKVRELLGIP-DTYAVAAVLP
TH_3507|M.thermoresistible__bu PTVQNFCLALRNLGVGSALTTLLCQV--EPEVRELLAIP-EGVATAAHIA
MMAR_2938|M.marinum_M PAVQNLLLAARAAGLGAGLITVPLWS--TVLARRALGLP-WNVTPCAVVP
MUL_2198|M.ulcerans_Agy99 PAVQNLLLAARAAGLGAGLITVPLWS--TVLARRALGLP-RNVTPCAVVP
Mb3403c|M.bovis_AF2122/97 PAVWSFCLALRSRGLGSCWTTLHLLDNGEHKVADVLGIPYDEYSQGGLLP
Rv3368c|M.tuberculosis_H37Rv PAVWSFCLALRSRGLGSCWTTLHLLDNGEHKVADVLGIPYDEYSQGGLLP
MLBr_00418|M.leprae_Br4923 PAVWSFCLALRSRGLGTCWTSLHLLGDGEQRAAEVLGIPSDKYSQGGLFP
MAV_1266|M.avium_104 PPVWNFQLALHTRGYGTCITTLHLHH--EDEVAQLLGIP-PTYVQGCLLP
* * .. *: : * * :: . *.:* ..
Mflv_2149|M.gilvum_PYR-GCK MG-RPLR-QVTKLTRRPVAEFATRENFDGESL------------------
Mvan_4554|M.vanbaalenii_PYR-1 LG-RPQR-QVTKLTRRPVSQFATRERFDGESL------------------
MSMEG_5155|M.smegmatis_MC2_155 LG-KPVH-QPTKLTRKPVSEIATRERFDGAPF------------------
MAB_4760|M.abscessus_ATCC_1997 IG-KPVK-QLTRLRRNRAAEFVTRERFDGPPWRTTTGEHHSESPRYPRSH
TH_3507|M.thermoresistible__bu IG-YPRDPFPAKLTRLPVEDVVAAETYDQPFFAPTTV-------------
MMAR_2938|M.marinum_M LG-WPIG-KYGPTTRRPVAEIVSLDRYGNRAFR-----------------
MUL_2198|M.ulcerans_Agy99 LG-WPIG-KYGPTTRRPVAEIVSLDRYGNRAFR-----------------
Mb3403c|M.bovis_AF2122/97 IA-YTQGIDFRPAKRLPAESVTHWNGW-----------------------
Rv3368c|M.tuberculosis_H37Rv IA-YTQGIDFRPAKRLPAESVTHWNGW-----------------------
MLBr_00418|M.leprae_Br4923 IA-YTKGTDFRPANRLPAENVTHWDIW-----------------------
MAV_1266|M.avium_104 VGRLRAGRTFRPARRRPIQEVIACDRWDGPPL------------------
:. * .. : :