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MDLYDVMRTTGAVRQFTGDPLPDEVLVRILDNARFAPSGGNRQGVHVIAVRDRATREALGALSVTGARRY IAQQRNGEGPWNPLRPMQISAEQLAATEVPAELSAPLLTSAVVLVVCVDLAVVAAFDQDLDRVGLIAGAS AYPFVWNVLLAARNEGFGGVLTTMAVAEEPGVKALLGIPDDHAVAAVLPLGRPQRQVTKLTRRPVSQFAT RERFDGESL
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. vanbaalenii PYR-1 | Mvan_4554 | - | - | 100% (219) | nitroreductase |
| M. vanbaalenii PYR-1 | Mvan_3115 | - | 5e-14 | 28.44% (218) | nitroreductase |
| M. vanbaalenii PYR-1 | Mvan_5547 | - | 1e-13 | 27.06% (218) | nitroreductase |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb3403c | - | 5e-12 | 28.21% (195) | oxidoreductase |
| M. gilvum PYR-GCK | Mflv_2149 | - | 1e-101 | 81.28% (219) | nitroreductase |
| M. tuberculosis H37Rv | Rv3368c | - | 5e-12 | 28.21% (195) | oxidoreductase |
| M. leprae Br4923 | MLBr_00418 | - | 3e-12 | 31.55% (187) | putative oxidoreductase |
| M. abscessus ATCC 19977 | MAB_4760 | - | 4e-42 | 66.95% (118) | nitroreductase |
| M. marinum M | MMAR_2938 | - | 4e-17 | 29.44% (214) | nitroreductase |
| M. avium 104 | MAV_0933 | - | 1e-14 | 29.72% (212) | nitroreductase family protein |
| M. smegmatis MC2 155 | MSMEG_5155 | - | 4e-89 | 72.69% (216) | nitroreductase |
| M. thermoresistible (build 8) | TH_3507 | - | 4e-33 | 39.63% (217) | PUTATIVE putative nitroreductase |
| M. ulcerans Agy99 | MUL_2198 | - | 2e-17 | 29.44% (214) | nitroreductase |
CLUSTAL 2.0.9 multiple sequence alignment
MMAR_2938|M.marinum_M ------MPLEDAMRTQRSIRRLK--SDPVDDSLVLHLLELAMKAPTGSNA
MUL_2198|M.ulcerans_Agy99 ------MPLEDAMRTQRSIRRLK--SDPVDDSLVLHLLELAMKAPTGSNA
MAV_0933|M.avium_104 -----------MMSTARTIRRFT--DEPVDDATLARCLGAARWAPSGANA
Mb3403c|M.bovis_AF2122/97 --MTLNLSVDEVLTTTRSVRKRLDFDKPVPRDVLMECLELALQAPTGSNS
Rv3368c|M.tuberculosis_H37Rv --MTLNLSVDEVLTTTRSVRKRLDFDKPVPRDVLMECLELALQAPTGSNS
MLBr_00418|M.leprae_Br4923 ------MSVDEVLTTTRSVRKRLDFDKPVPRDVLMECLQLALQAPTGSNS
Mvan_4554|M.vanbaalenii_PYR-1 ------MDLYDVMRTTGAVRQFT--GDPLPDEVLVRILDNARFAPSGGNR
Mflv_2149|M.gilvum_PYR-GCK MRQDLNMDLYDVMRTTGAVRQFT--GDPLPDDVLRRILDHARFAPSGGNR
MSMEG_5155|M.smegmatis_MC2_155 ------MEFTDVVRTTAAIRQFT--GDPLPDDVLRRILDNARFAPSGGNR
MAB_4760|M.abscessus_ATCC_1997 --------------------------------------------------
TH_3507|M.thermoresistible__bu ------VELVEAMRTTGTCRYFR--PDPVPDEVLYQAFDHARFAPQGGNR
MMAR_2938|M.marinum_M QNWEFIVVKDREVVAKLGRLNRRAMQLFGPIYRRSIARR---------GD
MUL_2198|M.ulcerans_Agy99 QNWEFIVVKDREVVAKLGRLNRRAMQLFGPIYRRSIARR---------GD
MAV_0933|M.avium_104 QGWRFVVLRSPEQRAVVAKAAAQALEVIEPVYGMSRPAP---------DD
Mb3403c|M.bovis_AF2122/97 QGWQWVFVEDAAKKKAIADVYLANARGYLSGPAPEYPDG---------DT
Rv3368c|M.tuberculosis_H37Rv QGWQWVFVEDAAKKKAIADVYLANARGYLSGPAPEYPDG---------DT
MLBr_00418|M.leprae_Br4923 QGWHWVFVEDAEKRKAIGDIYLVNARCYLSQPAPEYPEG---------DT
Mvan_4554|M.vanbaalenii_PYR-1 QGVHVIAVRDRATREALGALSVTGARRYIAQQRNGEGPWNPLRPMQISAE
Mflv_2149|M.gilvum_PYR-GCK QGVHVIAVRDVATRRALAELSRTGARRYLAQKHNGEGPWNPLRPMKVTAD
MSMEG_5155|M.smegmatis_MC2_155 QGTRVVVIRDRDTREALAELTITGSRRYIAQKRIGENPWNPLHPTAVTEA
MAB_4760|M.abscessus_ATCC_1997 --------------------------------------------------
TH_3507|M.thermoresistible__bu QPVRWIVVRDPARKAALQDLYLPLWKNYLSGIADGTVNVGALP-------
MMAR_2938|M.marinum_M E--KMLRLQKAVQWQADHFEEIPVVVVACLRGVIAPWPRISTSSAYGSIY
MUL_2198|M.ulcerans_Agy99 E--KMLRLQKAVQWQADHFEEIPVVVVACLRGVIAPWPRISTSSAYGSIY
MAV_0933|M.avium_104 HS-RRARTYRATYELHDRAGEFTSVLFA-----QAHYPTASELLLGGSIF
Mb3403c|M.bovis_AF2122/97 RGERMGRVRDSATYLAEHMHRAPVLLIPCLKG-REDESAVGGVSFWASLF
Rv3368c|M.tuberculosis_H37Rv RGERMGRVRDSATYLAEHMHRAPVLLIPCLKG-REDESAVGGVSFWASLF
MLBr_00418|M.leprae_Br4923 RGERMRLVRDSATYLAEHMHEVPVLLIPCLLG-RAEESPLGAVSYWASLF
Mvan_4554|M.vanbaalenii_PYR-1 QLAATEVPAELSAPLLTSAVVLVVCVDLAVVAAFDQDLDRVGLIAGASAY
Mflv_2149|M.gilvum_PYR-GCK EVAAIEVPEQMTAPLLTAAVVLVFSVDLDVVAAIDQDLDRIGLVAGASVY
MSMEG_5155|M.smegmatis_MC2_155 DLAAVDVPR--ATPLLDAAVVLVVCVDLGVVAAFDQDLDRIGVVSGASVY
MAB_4760|M.abscessus_ATCC_1997 -----MVPESVAAPLRTAGAVLVVCVDLRLVAAVDQDLERVGVVGGASIY
TH_3507|M.thermoresistible__bu --KTVRDADYFAEHLAEAPAIVVACAELDGLHPTDTDLGRLSIVGGASVY
.* :
MMAR_2938|M.marinum_M PAVQNLLLAARAAGLGAGLITVPLWS--TVLARRALGLPWN-VTPCAVVP
MUL_2198|M.ulcerans_Agy99 PAVQNLLLAARAAGLGAGLITVPLWS--TVLARRALGLPRN-VTPCAVVP
MAV_0933|M.avium_104 PAMQNFLLAARAQGLGACLTSWASYGG-EQLLREAVGVPEG-WMIAGHIV
Mb3403c|M.bovis_AF2122/97 PAVWSFCLALRSRGLGSCWTTLHLLDNGEHKVADVLGIPYDEYSQGGLLP
Rv3368c|M.tuberculosis_H37Rv PAVWSFCLALRSRGLGSCWTTLHLLDNGEHKVADVLGIPYDEYSQGGLLP
MLBr_00418|M.leprae_Br4923 PAVWSFCLALRSRGLGTCWTSLHLLGDGEQRAAEVLGIPSDKYSQGGLFP
Mvan_4554|M.vanbaalenii_PYR-1 PFVWNVLLAARNEGFGGVLTTMAVAE--EPGVKALLGIPDD-HAVAAVLP
Mflv_2149|M.gilvum_PYR-GCK PFVWNVLLAARNEGFGGVLTTMAVAE--EPRVKELLGLPDE-HAVAAIVP
MSMEG_5155|M.smegmatis_MC2_155 PFVWNILLSARNEGFGGVLTTMAIAE--EPKVKELLAIPDD-YAVAAVLP
MAB_4760|M.abscessus_ATCC_1997 PLVWNILLAARAEGYGGALTTMAVAE--EPKVRELLGIPDT-YAVAAVLP
TH_3507|M.thermoresistible__bu PTVQNFCLALRNLGVGSALTTLLCQV--EPEVRELLAIPEG-VATAAHIA
* : .. *: * * * : :.:* . .
MMAR_2938|M.marinum_M LGWPIGK-YGPTTRRPVAEIVSLDRYGNRAFR-----------------
MUL_2198|M.ulcerans_Agy99 LGWPIGK-YGPTTRRPVAEIVSLDRYGNRAFR-----------------
MAV_0933|M.avium_104 VGWPKGK-HGPLRRRPLAEFVNLDRWDAPADGLLSGL------------
Mb3403c|M.bovis_AF2122/97 IAYTQGIDFRPAKRLPAESVTHWNGW-----------------------
Rv3368c|M.tuberculosis_H37Rv IAYTQGIDFRPAKRLPAESVTHWNGW-----------------------
MLBr_00418|M.leprae_Br4923 IAYTKGTDFRPANRLPAENVTHWDIW-----------------------
Mvan_4554|M.vanbaalenii_PYR-1 LGRPQR-QVTKLTRRPVSQFATRERFDGESL------------------
Mflv_2149|M.gilvum_PYR-GCK MGRPLR-QVTKLTRRPVAEFATRENFDGESL------------------
MSMEG_5155|M.smegmatis_MC2_155 LGKPVH-QPTKLTRKPVSEIATRERFDGAPF------------------
MAB_4760|M.abscessus_ATCC_1997 IGKPVK-QLTRLRRNRAAEFVTRERFDGPPWRTTTGEHHSESPRYPRSH
TH_3507|M.thermoresistible__bu IGYPRDPFPAKLTRLPVEDVVAAETYDQPFFAPTTV-------------
:. . * ... : :