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M. thermoresistible (build 8) TH_2448 (-)

annotation: nitroreductase
coordinates: 2086193 - 2086903
length: 237

aa seq not available

Operon Prediction Model: Genebank

Paralogs
speciesidgenee-valueidentity (len)annotation
M. thermoresistible (build 8)TH_2448--100% (237)nitroreductase
M. thermoresistible (build 8)TH_4633-3e-2734.21% (228) PUTATIVE putative nitroreductase
M. thermoresistible (build 8)TH_2121-2e-2635.65% (216) POSSIBLE OXIDOREDUCTASE

Closest Orthologs (e-value cutoff: 1e-4)
speciesidgenee-valueidentity (len)annotation
M. bovis AF2122 / 97Mb3403c-5e-2130.00% (220) oxidoreductase
M. gilvum PYR-GCKMflv_3382-2e-9974.45% (227) nitroreductase
M. tuberculosis H37RvRv3368c-5e-2130.00% (220) oxidoreductase
M. leprae Br4923MLBr_00418-3e-1929.25% (212) putative oxidoreductase
M. abscessus ATCC 19977MAB_3693c-9e-2632.74% (223) oxidoreductase
M. marinum MMMAR_2938-2e-7162.50% (216) nitroreductase
M. avium 104MAV_1266-5e-2430.69% (202) nitroreductase family protein
M. smegmatis MC2 155MSMEG_1635-9e-2432.11% (218) nitroreductase family protein
M. ulcerans Agy99MUL_2198-1e-7162.50% (216) nitroreductase
M. vanbaalenii PYR-1Mvan_3115-1e-10475.86% (232) nitroreductase

CLUSTAL 2.0.9 multiple sequence alignment


TH_2448|M.thermoresistible__bu      MPDTPKPIPSVAEALARLDMPLAEAMMTQRAVRR--VLPDPVDDELVLKC
Mvan_3115|M.vanbaalenii_PYR-1       ---MPEPIPSAAEALARLDMPLVEAMMTQRAIRR--VLPDPVDDEIVLKC
Mflv_3382|M.gilvum_PYR-GCK          ---MADPTPSTSEALARLDMSLIDVMMTQRAVRR--VYPDPVDDEIVMKC
MMAR_2938|M.marinum_M               -------------------MPLEDAMRTQRSIRR--LKSDPVDDSLVLHL
MUL_2198|M.ulcerans_Agy99           -------------------MPLEDAMRTQRSIRR--LKSDPVDDSLVLHL
Mb3403c|M.bovis_AF2122/97           ---------------MTLNLSVDEVLTTTRSVRKRLDFDKPVPRDVLMEC
Rv3368c|M.tuberculosis_H37Rv        ---------------MTLNLSVDEVLTTTRSVRKRLDFDKPVPRDVLMEC
MLBr_00418|M.leprae_Br4923          -------------------MSVDEVLTTTRSVRKRLDFDKPVPRDVLMEC
MSMEG_1635|M.smegmatis_MC2_155      ---------------MTLNLSVDELLTTTRSVRKRLDFEKPVSREVILEC
MAB_3693c|M.abscessus_ATCC_199      --------------MTSLNLSADEVLTTTRSVRKRLDFDKPVERAVVEEC
MAV_1266|M.avium_104                -------------------MNVEYLLTATPSARKSLDLDAPVEPGDIREC
                                                       :     : :  : *:      **    : . 

TH_2448|M.thermoresistible__bu      IELALRAPTGSNGQNWEFIVVKDPAVKAKLADRYRQAWAVYGG---IGRR
Mvan_3115|M.vanbaalenii_PYR-1       LELALRAPTGANGQNWEFVVVKDPKIKRKLQRRYRLAWRVFHR---TSIR
Mflv_3382|M.gilvum_PYR-GCK          LEVALHAPTGANGQNWEFIVVKDYETKKKLAKRYRQAWNLYYQ---TVIR
MMAR_2938|M.marinum_M               LELAMKAPTGSNAQNWEFIVVKDREVVAKLGRLNRRAMQLFGP---IYRR
MUL_2198|M.ulcerans_Agy99           LELAMKAPTGSNAQNWEFIVVKDREVVAKLGRLNRRAMQLFGP---IYRR
Mb3403c|M.bovis_AF2122/97           LELALQAPTGSNSQGWQWVFVEDAAKKKAIADVYLANARGYLSGPAPEYP
Rv3368c|M.tuberculosis_H37Rv        LELALQAPTGSNSQGWQWVFVEDAAKKKAIADVYLANARGYLSGPAPEYP
MLBr_00418|M.leprae_Br4923          LQLALQAPTGSNSQGWHWVFVEDAEKRKAIGDIYLVNARCYLSQPAPEYP
MSMEG_1635|M.smegmatis_MC2_155      LDLALQAPTGSNAQGWQWVFVEDEAKKKALADIYRSNAIPYLEQEAAER-
MAB_3693c|M.abscessus_ATCC_199      LNIAMQAPTGSNHQGWHWVIVEDAEKKKAIADIYREGWNKYAKGAGATYA
MAV_1266|M.avium_104                LRIGLQAANGSNAQSWRWLVVSDPALRARIAELYRD---AYLRRVGGRLL
                                    : :.::*..*:* *.*.::.*.*      :          :         

TH_2448|M.thermoresistible__bu      -VTAG-DESMAKILRAVQWQVDHFTEIPVLVVACLRAGPREGRLPFMPAP
Mvan_3115|M.vanbaalenii_PYR-1       DIASY-DEEMAKSVRAIEWQLEHFHEIPVLVIACLRLSAREGKVPYVPMP
Mflv_3382|M.gilvum_PYR-GCK          RVSKR-DPSMAKTARAVQWQVDHFTEVPVLIVACLKLGPKDGRIPFVPMP
MMAR_2938|M.marinum_M               SIARRGDEKMLRLQKAVQWQADHFEEIPVVVVACLRG-------VIAPWP
MUL_2198|M.ulcerans_Agy99           SIARRGDEKMLRLQKAVQWQADHFEEIPVVVVACLRG-------VIAPWP
Mb3403c|M.bovis_AF2122/97           DGDTRG-ERMGRVRDSATYLAEHMHRAPVLLIPCLK-------GREDESA
Rv3368c|M.tuberculosis_H37Rv        DGDTRG-ERMGRVRDSATYLAEHMHRAPVLLIPCLK-------GREDESA
MLBr_00418|M.leprae_Br4923          EGDTRG-ERMRLVRDSATYLAEHMHEVPVLLIPCLL-------GRAEESP
MSMEG_1635|M.smegmatis_MC2_155      -GDIRD-QQQPKVRDSARHLTDNFEKAPVLLIPCLE-------GRPDGAP
MAB_3693c|M.abscessus_ATCC_199      EGDTRA-ERKAKVVDSAGYLAENFERSPLFLIPCIE-------GRLDNLP
MAV_1266|M.avium_104                AGLMPAGTPESRIMSSTEWLVENLARVPMLVIPCYEPYL----PRIDGDE
                                                   :     ::: . *:.::.*                

TH_2448|M.thermoresistible__bu      PVAASSFFGSIYPSVQNLLLAARAMGLGASLITLPLWS--MTSARRILKL
Mvan_3115|M.vanbaalenii_PYR-1       HAAASAFFGSIYPSVQNLLLAARAMGLGASLITLPLWN--LTSARRVLKL
Mflv_3382|M.gilvum_PYR-GCK          HAALSGFYGSIYPSVQNLLLAARAMGLGASLITLPLWS--VTSTRKTLGL
MMAR_2938|M.marinum_M               RISTSSAYGSIYPAVQNLLLAARAAGLGAGLITVPLWS--TVLARRALGL
MUL_2198|M.ulcerans_Agy99           RISTSSAYGSIYPAVQNLLLAARAAGLGAGLITVPLWS--TVLARRALGL
Mb3403c|M.bovis_AF2122/97           VG-GVSFWASLFPAVWSFCLALRSRGLGSCWTTLHLLDNGEHKVADVLGI
Rv3368c|M.tuberculosis_H37Rv        VG-GVSFWASLFPAVWSFCLALRSRGLGSCWTTLHLLDNGEHKVADVLGI
MLBr_00418|M.leprae_Br4923          LG-AVSYWASLFPAVWSFCLALRSRGLGTCWTSLHLLGDGEQRAAEVLGI
MSMEG_1635|M.smegmatis_MC2_155      AGLSASFWGSLLPAVWSFMLALRSRGLGSAWTTLHLLGEGEKQAAEVVGI
MAB_3693c|M.abscessus_ATCC_199      VVGAASSWGSLLPAVWSFMLAARNRGLGSAWTTLHLMDDGEKRTADIVGI
MAV_1266|M.avium_104                SFHLATLYGSIFPPVWNFQLALHTRGYGTCITTLHLHH--EDEVAQLLGI
                                           :.*: *.* .: ** :  * *:   :: *       .   : :

TH_2448|M.thermoresistible__bu      P-LSVTPCCIVPLG-WPRGR-YGPTTRRPVREVVHLDSYGNRAWQSPS--
Mvan_3115|M.vanbaalenii_PYR-1       P-TEVTPCCVVPLG-WPRGR-YGPTTRRPVDEVVHLDRYGNRAWFGPRGA
Mflv_3382|M.gilvum_PYR-GCK          P-VSVTPCCVVPLG-WPRGR-YGPTTRRPVAEVMHLNTYGNRPWMGTG--
MMAR_2938|M.marinum_M               P-WNVTPCAVVPLG-WPIGK-YGPTTRRPVAEIVSLDRYGNRAFR-----
MUL_2198|M.ulcerans_Agy99           P-RNVTPCAVVPLG-WPIGK-YGPTTRRPVAEIVSLDRYGNRAFR-----
Mb3403c|M.bovis_AF2122/97           PYDEYSQGGLLPIA-YTQGIDFRPAKRLPAESVTHWNGW-----------
Rv3368c|M.tuberculosis_H37Rv        PYDEYSQGGLLPIA-YTQGIDFRPAKRLPAESVTHWNGW-----------
MLBr_00418|M.leprae_Br4923          PSDKYSQGGLFPIA-YTKGTDFRPANRLPAENVTHWDIW-----------
MSMEG_1635|M.smegmatis_MC2_155      PFDKYSQAGLFPIA-YTIGTDFKKAKRLPAEQFAHWDTW-----------
MAB_3693c|M.abscessus_ATCC_199      PFDKVTQGGLFPIA-YTVGTDFRLAKRQPLADVLHWDTW-----------
MAV_1266|M.avium_104                P-PTYVQGCLLPVGRLRAGRTFRPARRRPIQEVIACDRWDGPPL------
                                    *        :.*:.    *  :  : * *  ..   : :           

TH_2448|M.thermoresistible__bu      ---
Mvan_3115|M.vanbaalenii_PYR-1       DRP
Mflv_3382|M.gilvum_PYR-GCK          ---
MMAR_2938|M.marinum_M               ---
MUL_2198|M.ulcerans_Agy99           ---
Mb3403c|M.bovis_AF2122/97           ---
Rv3368c|M.tuberculosis_H37Rv        ---
MLBr_00418|M.leprae_Br4923          ---
MSMEG_1635|M.smegmatis_MC2_155      ---
MAB_3693c|M.abscessus_ATCC_199      ---
MAV_1266|M.avium_104                ---