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M. avium 104 MAV_4334 (-)

annotation: nitroreductase family protein
coordinates: 4466960 - 4467607
length: 215

TLNLSVDEVLTTTRSVRKRLDFDKPVPREVLMECLELALQAPTGSNAQGWQWVFVEDADKKKAIADIYLA
NARAYLSLPAAEYPEGDTRGERMPKVKDSAVYLAEHMHEAPVLLIPCLEGRVENAPLGLSASFWASLFPA
AWSFCLALRSRGLGTCWTTLHLINDGEKQAAELLGIPHDRYSQGGLFPIAYTKGTDFRPAKRLPAEQVTH
WDSW*
Operon Prediction Model: Genebank

Paralogs
speciesidgenee-valueidentity (len)annotation
M. avium 104MAV_4334--100% (215)nitroreductase family protein
M. avium 104MAV_1266-8e-3539.81% (216) nitroreductase family protein
M. avium 104MAV_0933-2e-1327.54% (207) nitroreductase family protein

Closest Orthologs (e-value cutoff: 1e-4)
speciesidgenee-valueidentity (len)annotation
M. bovis AF2122 / 97Mb3403c-1e-10380.93% (215) oxidoreductase
M. gilvum PYR-GCKMflv_4892-6e-9476.85% (216) nitroreductase
M. tuberculosis H37RvRv3368c-1e-10380.93% (215) oxidoreductase
M. leprae Br4923MLBr_00418-1e-10482.94% (211) putative oxidoreductase
M. abscessus ATCC 19977MAB_3693c-2e-8065.42% (214) oxidoreductase
M. marinum MMMAR_1160-1e-10782.79% (215) nitroreductase
M. smegmatis MC2 155MSMEG_1635-7e-9173.49% (215) nitroreductase family protein
M. thermoresistible (build 8)TH_2121-1e-9677.21% (215) POSSIBLE OXIDOREDUCTASE
M. ulcerans Agy99MUL_2854-1e-10782.79% (215) nitroreductase
M. vanbaalenii PYR-1Mvan_1532-3e-9072.69% (216) nitroreductase

CLUSTAL 2.0.9 multiple sequence alignment


Mb3403c|M.bovis_AF2122/97           -MTLNLSVDEVLTTTRSVRKRLDFDKPVPRDVLMECLELALQAPTGSNSQ
Rv3368c|M.tuberculosis_H37Rv        -MTLNLSVDEVLTTTRSVRKRLDFDKPVPRDVLMECLELALQAPTGSNSQ
MMAR_1160|M.marinum_M               -MTLNLSVDEVLTTTRSVRKRLDFDKPVSREVLMECLDLALQAPTGSNSQ
MUL_2854|M.ulcerans_Agy99           -MTLNLSVDEVLTTTRSVRKRLDFDKPVSREVLMECLDLALQAPTGSNSQ
MLBr_00418|M.leprae_Br4923          -----MSVDEVLTTTRSVRKRLDFDKPVPRDVLMECLQLALQAPTGSNSQ
MAV_4334|M.avium_104                -MTLNLSVDEVLTTTRSVRKRLDFDKPVPREVLMECLELALQAPTGSNAQ
TH_2121|M.thermoresistible__bu      -MALNLSVDDVLTTTRSVRKRLDLEKPVPREVLMECLELALQAPTGSNAQ
Mflv_4892|M.gilvum_PYR-GCK          -MTLNLSADEVLTTTRSVRKRLDFDRPVPREVLNECLEIALQAPTGSNAQ
Mvan_1532|M.vanbaalenii_PYR-1       -MTLNLSADEVLTTTRSVRKRLDFDKPVPRDVLMECLDIALQAPTGSNNQ
MSMEG_1635|M.smegmatis_MC2_155      -MTLNLSVDELLTTTRSVRKRLDFEKPVSREVILECLDLALQAPTGSNAQ
MAB_3693c|M.abscessus_ATCC_199      MTSLNLSADEVLTTTRSVRKRLDFDKPVERAVVEECLNIAMQAPTGSNHQ
                                         :*.*::************:::** * *: ***::*:******* *

Mb3403c|M.bovis_AF2122/97           GWQWVFVEDAAKKKAIADVYLANARGYLSGPAPEYPDGDTRGERMGRVRD
Rv3368c|M.tuberculosis_H37Rv        GWQWVFVEDAAKKKAIADVYLANARGYLSGPAPEYPDGDTRGERMGRVRD
MMAR_1160|M.marinum_M               GWQWVFVEDADKKKAIAEVYLARARSYLSMPAPEYAEGDTRGERMGKVRD
MUL_2854|M.ulcerans_Agy99           GWQWVFVEDADKKKAIADVYLARARSYLSMPAPEYAEGDTRGERMGKVRD
MLBr_00418|M.leprae_Br4923          GWHWVFVEDAEKRKAIGDIYLVNARCYLSQPAPEYPEGDTRGERMRLVRD
MAV_4334|M.avium_104                GWQWVFVEDADKKKAIADIYLANARAYLSLPAAEYPEGDTRGERMPKVKD
TH_2121|M.thermoresistible__bu      GWQWVFVEDPDTKKALADIYRVNADAYLDRPRPSY--DDVRGERMDRVKS
Mflv_4892|M.gilvum_PYR-GCK          GWQFVFVDDPEKKKALADIYRIAADPYLEAEKPTF--GDVRDERTPLVVD
Mvan_1532|M.vanbaalenii_PYR-1       GWQWVFVEDPEKKKAIADIYRTNATPYLAMEKPAT--GDMRDGQRPRVED
MSMEG_1635|M.smegmatis_MC2_155      GWQWVFVEDEAKKKALADIYRSNAIPYLEQEAAER--GDIRDQQQPKVRD
MAB_3693c|M.abscessus_ATCC_199      GWHWVIVEDAEKKKAIADIYREGWNKYAKGAGATYAEGDTRAERKAKVVD
                                    **::*:*:*  .:**:.::*      *     .    .* *  :   * .

Mb3403c|M.bovis_AF2122/97           SATYLAEHMHRAPVLLIPCLKGREDESAVG-GVSFWASLFPAVWSFCLAL
Rv3368c|M.tuberculosis_H37Rv        SATYLAEHMHRAPVLLIPCLKGREDESAVG-GVSFWASLFPAVWSFCLAL
MMAR_1160|M.marinum_M               SATYLAEHMHEAPVLMIPCIQGREDKSPLG-GVSFWASLFPAVWSFCLAL
MUL_2854|M.ulcerans_Agy99           SATYLAEHMHEAPVLMIPCIQGREDKSPLG-GVSLWASLFPAVWSFCLAL
MLBr_00418|M.leprae_Br4923          SATYLAEHMHEVPVLLIPCLLGRAEESPLG-AVSYWASLFPAVWSFCLAL
MAV_4334|M.avium_104                SAVYLAEHMHEAPVLLIPCLEGRVENAPLGLSASFWASLFPAAWSFCLAL
TH_2121|M.thermoresistible__bu      SARYLSEHFHEVPVLLVPCLEGRPDNQPAGVTASFWGSLLPAVWSFMLAL
Mflv_4892|M.gilvum_PYR-GCK          SAKYLAEHLHEAPVMLIPCLEGRPDGAPAGMSAGFWGSLLPAVWSFMLAL
Mvan_1532|M.vanbaalenii_PYR-1       SARYLNEHLEKVPVMLIPCLQGKPQDAVSGASAGYWGSLLPAVWSFMLAL
MSMEG_1635|M.smegmatis_MC2_155      SARHLTDNFEKAPVLLIPCLEGRPDGAPAGLSASFWGSLLPAVWSFMLAL
MAB_3693c|M.abscessus_ATCC_199      SAGYLAENFERSPLFLIPCIEGRLDNLPVVGAASSWGSLLPAVWSFMLAA
                                    ** :* :::.. *::::**: *: :       .. *.**:**.*** ** 

Mb3403c|M.bovis_AF2122/97           RSRGLGSCWTTLHLLDNGEHKVADVLGIPYDEYSQGGLLPIAYTQGIDFR
Rv3368c|M.tuberculosis_H37Rv        RSRGLGSCWTTLHLLDNGEHKVADVLGIPYDEYSQGGLLPIAYTQGIDFR
MMAR_1160|M.marinum_M               RSRGLGSCWTTLHLLADGERQVADVLGIPYDDYSQGGLFPIAYTKGTDFR
MUL_2854|M.ulcerans_Agy99           RSRGLGSCWTTLHLLADGERQVADVLGIPYDDYSQGGLFPIAYTKGTDFR
MLBr_00418|M.leprae_Br4923          RSRGLGTCWTSLHLLGDGEQRAAEVLGIPSDKYSQGGLFPIAYTKGTDFR
MAV_4334|M.avium_104                RSRGLGTCWTTLHLINDGEKQAAELLGIPHDRYSQGGLFPIAYTKGTDFR
TH_2121|M.thermoresistible__bu      RSRGLGSAWTTLHLVGDGEQRAAEVLGIPFDRYSQAGLFPIAYTKGTDFR
Mflv_4892|M.gilvum_PYR-GCK          RSRGLGSAWTTLHLIGDGEKQAAEVLGIPFDKYSQGGLFPIAYTKGTDFK
Mvan_1532|M.vanbaalenii_PYR-1       RSRGLGSAWTTLHLLGDGERQAAEILGIPFDNYSQAGLFPIAYTKGTDFR
MSMEG_1635|M.smegmatis_MC2_155      RSRGLGSAWTTLHLLGEGEKQAAEVVGIPFDKYSQAGLFPIAYTIGTDFK
MAB_3693c|M.abscessus_ATCC_199      RNRGLGSAWTTLHLMDDGEKRTADIVGIPFDKVTQGGLFPIAYTVGTDFR
                                    *.****:.**:***: :**::.*:::*** *  :*.**:***** * **:

Mb3403c|M.bovis_AF2122/97           PAKRLPAESVTHWNGW
Rv3368c|M.tuberculosis_H37Rv        PAKRLPAESVTHWNGW
MMAR_1160|M.marinum_M               PAKRLPADRLTHWNSW
MUL_2854|M.ulcerans_Agy99           PAKRLPADRLTHWNSW
MLBr_00418|M.leprae_Br4923          PANRLPAENVTHWDIW
MAV_4334|M.avium_104                PAKRLPAEQVTHWDSW
TH_2121|M.thermoresistible__bu      PAKRLPAEQVVHWNRW
Mflv_4892|M.gilvum_PYR-GCK          KAKRLPAEQLTHWNTW
Mvan_1532|M.vanbaalenii_PYR-1       RAKRLPAEQLTHWDTW
MSMEG_1635|M.smegmatis_MC2_155      KAKRLPAEQFAHWDTW
MAB_3693c|M.abscessus_ATCC_199      LAKRQPLADVLHWDTW
                                     *:* *   . **: *