For questions or suggestions e-mail us at: ioerger@cs.tamu.edu

M. thermoresistible (build 8) TH_4633 (-)

annotation: putative nitroreductase
coordinates: 3458957 - 3459625
length: 223

aa seq not available

Operon Prediction Model: Genebank

Paralogs
speciesidgenee-valueidentity (len)annotation
M. thermoresistible (build 8)TH_4633--100% (223)putative nitroreductase
M. thermoresistible (build 8)TH_1618-1e-4949.75% (203) nitroreductase family protein
M. thermoresistible (build 8)TH_2448-2e-2734.21% (228) PUTATIVE nitroreductase

Closest Orthologs (e-value cutoff: 1e-4)
speciesidgenee-valueidentity (len)annotation
M. bovis AF2122 / 97Mb3403c-6e-1231.13% (212) oxidoreductase
M. gilvum PYR-GCKMflv_1262-3e-4848.26% (201) nitroreductase
M. tuberculosis H37RvRv3368c-6e-1231.13% (212) oxidoreductase
M. leprae Br4923MLBr_00418-3e-1131.75% (211) putative oxidoreductase
M. abscessus ATCC 19977MAB_3693c-1e-1631.34% (217) oxidoreductase
M. marinum MMMAR_4721-1e-5051.78% (197) nitroreductase
M. avium 104MAV_0933-2e-4950.76% (197) nitroreductase family protein
M. smegmatis MC2 155MSMEG_6627-8e-4648.78% (205) nitroreductase family protein
M. ulcerans Agy99MUL_2198-5e-2635.50% (200) nitroreductase
M. vanbaalenii PYR-1Mvan_5547-6e-4647.06% (204) nitroreductase

CLUSTAL 2.0.9 multiple sequence alignment


Mflv_1262|M.gilvum_PYR-GCK          --------------MDMPHPTDNVWEVLSTARSIRR--FTDEPVDSATLD
Mvan_5547|M.vanbaalenii_PYR-1       MAKMLDICLRVLYTIDMPHPTDDVWEVLSTARSIRR--FTDEPVTDAVID
MSMEG_6627|M.smegmatis_MC2_155      ----------------MPQPTNDVWEVLSTARSIRR--FTDEPVDDATLH
MMAR_4721|M.marinum_M               ---------------------------MSTARTVRR--FTDRPVDDATLT
MAV_0933|M.avium_104                --------------------------MMSTARTIRR--FTDEPVDDATLA
TH_4633|M.thermoresistible__bu      -------VDRHAAADDPAMTSPDLWTVLRTASAVRR--YRDEPVDDVVVE
MUL_2198|M.ulcerans_Agy99           ---------------------MPLEDAMRTQRSIRR--LKSDPVDDSLVL
Mb3403c|M.bovis_AF2122/97           -----------------MTLNLSVDEVLTTTRSVRKRLDFDKPVPRDVLM
Rv3368c|M.tuberculosis_H37Rv        -----------------MTLNLSVDEVLTTTRSVRKRLDFDKPVPRDVLM
MLBr_00418|M.leprae_Br4923          ---------------------MSVDEVLTTTRSVRKRLDFDKPVPRDVLM
MAB_3693c|M.abscessus_ATCC_199      ----------------MTSLNLSADEVLTTTRSVRKRLDFDKPVERAVVE
                                                               : *  ::*:    . **    : 

Mflv_1262|M.gilvum_PYR-GCK          RCLQAATWAPNGANAQLWRFIVLDGPEQRAAVAQAAQIALQSIESIYG--
Mvan_5547|M.vanbaalenii_PYR-1       RCLEAATWAPNGANAQLWRFIVLDGPEQRAAVGKAAQIALTSIEAIYG--
MSMEG_6627|M.smegmatis_MC2_155      RCLQAAAWAPNGANAQLWRFVVLDAPEQRAAVAGAARSALATIESIYG--
MMAR_4721|M.marinum_M               RCLEAATWAPSGANAQGWRFVVLRSPEQRAVVAAAAARALAVIEPVYG--
MAV_0933|M.avium_104                RCLGAARWAPSGANAQGWRFVVLRSPEQRAVVAKAAAQALEVIEPVYG--
TH_4633|M.thermoresistible__bu      RCLRAASWAPSGGNQQPWRFVVLRSPEVRAVITAAARRTWDVMADFYG--
MUL_2198|M.ulcerans_Agy99           HLLELAMKAPTGSNAQNWEFIVVKDREVVAKLGRLNRRAMQLFGPIYRRS
Mb3403c|M.bovis_AF2122/97           ECLELALQAPTGSNSQGWQWVFVEDAAKKKAIADVYLANARGYLSGPAPE
Rv3368c|M.tuberculosis_H37Rv        ECLELALQAPTGSNSQGWQWVFVEDAAKKKAIADVYLANARGYLSGPAPE
MLBr_00418|M.leprae_Br4923          ECLQLALQAPTGSNSQGWHWVFVEDAEKRKAIGDIYLVNARCYLSQPAPE
MAB_3693c|M.abscessus_ATCC_199      ECLNIAMQAPTGSNHQGWHWVIVEDAEKKKAIADIYREGWNKYAKGAGAT
                                    . *  *  **.*.* * *.::.:        :                  

Mflv_1262|M.gilvum_PYR-GCK          MTRPAP--EDDSRSARNNRATYELHDR--AGEFTSVLFVAYKNEFSSEFL
Mvan_5547|M.vanbaalenii_PYR-1       MTRPDD--DDASRAARNNRATYELHDR--AEEYTSVLFTAFKNEFSSEFL
MSMEG_6627|M.smegmatis_MC2_155      MSRPAD--DDHSRAARNNRATYELHDR--AGELTSVLFVAYKNEFASDYL
MMAR_4721|M.marinum_M               MRRPAA--DDDSRRARTYRATYELHDR--AGEFTSVLFAQQHYPTASELL
MAV_0933|M.avium_104                MSRPAP--DDHSRRARTYRATYELHDR--AGEFTSVLFAQAHYPTASELL
TH_4633|M.thermoresistible__bu      FDKPGT--ADDPK-SRVLGAMYEHMQVG-GGAPVCVLFCLRPQRGASDLQ
MUL_2198|M.ulcerans_Agy99           IARRGD--EKMLRLQKAVQWQADHFEEIPVVVVACLRGVIAPWPRISTSS
Mb3403c|M.bovis_AF2122/97           YPDGDTRGERMGRVRDSATYLAEHMHRAPVLLIPCLKGRED-ESAVGGVS
Rv3368c|M.tuberculosis_H37Rv        YPDGDTRGERMGRVRDSATYLAEHMHRAPVLLIPCLKGRED-ESAVGGVS
MLBr_00418|M.leprae_Br4923          YPEGDTRGERMRLVRDSATYLAEHMHEVPVLLIPCLLGRAE-ESPLGAVS
MAB_3693c|M.abscessus_ATCC_199      YAEGDTRAERKAKVVDSAGYLAENFERSPLFLIPCIEGRLDNLPVVGAAS
                                                          :  .        .:          .   

Mflv_1262|M.gilvum_PYR-GCK          QGGSIYPALQNFYLAARAQGLGACITSWASYGGE-QALREAVGIP-DEWF
Mvan_5547|M.vanbaalenii_PYR-1       QGGSIYPAIQNFYLAARAQGLGACLTSWASYAGGGQVLREAVGIP-DEWF
MSMEG_6627|M.smegmatis_MC2_155      QAGSIYPAMQNFYLAARAQGLGACFTSWAAYQGE-QILRDAVGVP-AEWF
MMAR_4721|M.marinum_M               LGGSIFPAMQNFLLAARAQGLGACMTSWASYGGE-RLLREAVGVP-EDWL
MAV_0933|M.avium_104                LGGSIFPAMQNFLLAARAQGLGACLTSWASYGGE-QLLREAVGVP-EGWM
TH_4633|M.thermoresistible__bu      QGGSIFPAVQNFLLAARAQGLGAAITLWHDACES--ELRSLVGIP-DDWR
MUL_2198|M.ulcerans_Agy99           AYGSIYPAVQNLLLAARAAGLGAGLITVPLWSTV--LARRALGLP-RNVT
Mb3403c|M.bovis_AF2122/97           FWASLFPAVWSFCLALRSRGLGSCWTTLHLLDNGEHKVADVLGIPYDEYS
Rv3368c|M.tuberculosis_H37Rv        FWASLFPAVWSFCLALRSRGLGSCWTTLHLLDNGEHKVADVLGIPYDEYS
MLBr_00418|M.leprae_Br4923          YWASLFPAVWSFCLALRSRGLGTCWTSLHLLGDGEQRAAEVLGIPSDKYS
MAB_3693c|M.abscessus_ATCC_199      SWGSLLPAVWSFMLAARNRGLGSAWTTLHLMDDGEKRTADIVGIPFDKVT
                                      .*: **: .: ** *  ***:                  :*:*     

Mflv_1262|M.gilvum_PYR-GCK          LAGHVVVGWPRGK-HGPVRRRPLSDVVFRNHWDPERADITYGRGARPRGK
Mvan_5547|M.vanbaalenii_PYR-1       LAGHIVVGWPRGH-HGPVRRRPLTDVVFRNRWDPERADITYGRGARPRGK
MSMEG_6627|M.smegmatis_MC2_155      LAGHVVIGRPRGR-HGPVRRRPLDDVVFRNTWDAARADIVYGQGARPSRT
MMAR_4721|M.marinum_M               LAGHIVIGWPQGK-HGPLRRRPLSDVVNLDRWDRPAFPGLGS--------
MAV_0933|M.avium_104                IAGHIVVGWPKGK-HGPLRRRPLAEFVNLDRWDAPADGLLSGL-------
TH_4633|M.thermoresistible__bu      IATLVTAGWPRGG-HHPVRRKPVCEVAAVDRWDQAWVSRMR---------
MUL_2198|M.ulcerans_Agy99           PCAVVPLGWPIGK-YGPTTRRPVAEIVSLDRYGNRAFR------------
Mb3403c|M.bovis_AF2122/97           QGGLLPIAYTQGIDFRPAKRLPAESVTHWNGW------------------
Rv3368c|M.tuberculosis_H37Rv        QGGLLPIAYTQGIDFRPAKRLPAESVTHWNGW------------------
MLBr_00418|M.leprae_Br4923          QGGLFPIAYTKGTDFRPANRLPAENVTHWDIW------------------
MAB_3693c|M.abscessus_ATCC_199      QGGLFPIAYTVGTDFRLAKRQPLADVLHWDTW------------------
                                        .  . . *  .    * *  ..   : :                  

Mflv_1262|M.gilvum_PYR-GCK          -
Mvan_5547|M.vanbaalenii_PYR-1       S
MSMEG_6627|M.smegmatis_MC2_155      -
MMAR_4721|M.marinum_M               -
MAV_0933|M.avium_104                -
TH_4633|M.thermoresistible__bu      -
MUL_2198|M.ulcerans_Agy99           -
Mb3403c|M.bovis_AF2122/97           -
Rv3368c|M.tuberculosis_H37Rv        -
MLBr_00418|M.leprae_Br4923          -
MAB_3693c|M.abscessus_ATCC_199      -