For questions or suggestions e-mail us at: ioerger@cs.tamu.edu
aa seq not available
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. thermoresistible (build 8) | TH_4243 | - | - | 100% (522) | General substrate transporter |
| M. thermoresistible (build 8) | TH_3714 | - | 9e-85 | 40.53% (412) | PUTATIVE major facilitator superfamily MFS_1 |
| M. thermoresistible (build 8) | TH_2446 | - | 2e-79 | 39.86% (424) | PUTATIVE major facilitator superfamily MFS_1 |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb1232 | - | 3e-66 | 33.65% (422) | integral membrane transport protein |
| M. gilvum PYR-GCK | Mflv_1471 | - | 0.0 | 78.57% (434) | general substrate transporter |
| M. tuberculosis H37Rv | Rv1200 | - | 3e-66 | 33.65% (422) | integral membrane transport protein |
| M. leprae Br4923 | - | - | - | - | - |
| M. abscessus ATCC 19977 | MAB_4485 | - | 1e-170 | 66.51% (436) | putative transporter |
| M. marinum M | MMAR_4238 | - | 4e-68 | 36.36% (429) | integral membrane transport protein |
| M. avium 104 | MAV_4627 | - | 1e-84 | 42.24% (419) | major facilitator superfamily protein |
| M. smegmatis MC2 155 | MSMEG_6027 | - | 0.0 | 76.26% (438) | major facilitator superfamily protein MFS_1 |
| M. ulcerans Agy99 | MUL_0949 | - | 1e-67 | 36.13% (429) | integral membrane transport protein |
| M. vanbaalenii PYR-1 | Mvan_5300 | - | 0.0 | 79.13% (436) | major facilitator superfamily transporter |
CLUSTAL 2.0.9 multiple sequence alignment
Mflv_1471|M.gilvum_PYR-GCK MSSTGSS--------------------TGLKRVVVASMAGTVVEWYEFFL
Mvan_5300|M.vanbaalenii_PYR-1 MSTQHDARPDGPPSI-----------TTGLKRVVVASMAGTVVEWYEFFL
TH_4243|M.thermoresistible__bu VSAPASG----------------------LKRVVAASMAGTVVEWYEFFL
MSMEG_6027|M.smegmatis_MC2_155 MSAPVPT---------------------GLRRVVVASMAGTVVEWYEFFL
MAB_4485|M.abscessus_ATCC_1997 MSTTAEADAAP----------------SGLRKVVAASMAGTVVEWYEFFL
MAV_4627|M.avium_104 MAATLPAPAPAGLADGHPLDESAEQQRRRLRIVVAASLLGTTVEWYDFFL
Mb1232|M.bovis_AF2122/97 -----------------------------MKRVALACLVGSAIEFYDFLI
Rv1200|M.tuberculosis_H37Rv -----------------------------MKRVALACLVGSAIEFYDFLI
MMAR_4238|M.marinum_M -----------------------------MSRVALACVVGSTVEYYDFCI
MUL_0949|M.ulcerans_Agy99 -----------------------------MSRVALACVVGSTVEYYDFCI
: *. *.: *:.:*:*:* :
Mflv_1471|M.gilvum_PYR-GCK YATAATLVFNKVFFAE---GTSEAAGLIAALLTYAVGFVARPLGGVVFGH
Mvan_5300|M.vanbaalenii_PYR-1 YATAATLVFNKVFFAE---GTSEAAGLIAALLTYAVGFVARPLGGVVFGH
TH_4243|M.thermoresistible__bu YGTAATLVFNKVFFAQ---GDNELDAILAAFVTYAVGFVARPLGGVVFGH
MSMEG_6027|M.smegmatis_MC2_155 YGTAATLVFNKVFFAQ---GGDALDAILAAFVTYAVGFIARPLGGIVFGH
MAB_4485|M.abscessus_ATCC_1997 YATAATLVFNKVFFPAVQAGGNDLDNIIKAFLTYAVGFVARPIGGIVFGH
MAV_4627|M.avium_104 YATAAGLVFNKVFFPN----ESSLVGTLLAFATFAVGFVMRPIGGLVFGH
Mb1232|M.bovis_AF2122/97 YGTAAALVFPTVFFPH----LDPTVAAVASMGTFAVAFLSRPFGAAVFGY
Rv1200|M.tuberculosis_H37Rv YGTAAALVFPTVFFPH----LDPTVAAVASMGTFAVAFLSRPFGAAVFGY
MMAR_4238|M.marinum_M YGTAAALVFPAVFYPG----LSPALATIASMGTFATAFLSRPLGAAVFGH
MUL_0949|M.ulcerans_Agy99 YGTAAALVFPAVFYPG----LSPALATIASMGTFATAFLSRPLGAAVFGH
*.*** *** **:. . : :: *:*..*: **:*. ***:
Mflv_1471|M.gilvum_PYR-GCK FGDKYGRKKLLQFAILLVGVVTFLMGCLPTYNQIGVWAPILLVVLRFVQG
Mvan_5300|M.vanbaalenii_PYR-1 FGDKYGRKKLLQFAILLVGAVTFLMGCLPTYAQIGVWAPILLVVLRFMQG
TH_4243|M.thermoresistible__bu FGDKYGRKKLLQFSILLVGAATFLMGCLPTFGQIGYWAPTLLVLLRFVQG
MSMEG_6027|M.smegmatis_MC2_155 YGDKFGRKKLLQFSLLLVGAATFLMGCLPTFGQIGYLAPTLLVILRFIQG
MAB_4485|M.abscessus_ATCC_1997 FGDRYGRKHLLQIAIVLVGVATFLMGCLPTFAQVGYAAPMLLVGLRFLQG
MAV_4627|M.avium_104 IGDRIGRKRSLALTMLIMGGATALIGVLPTAAQIGAWAPVLLLVLRVLQG
Mb1232|M.bovis_AF2122/97 FGDRLGRKKTLVATLLIMGLATVTVGLVPTTVAIGAAAPLILTTMRLLQG
Rv1200|M.tuberculosis_H37Rv FGDRLGRKKTLVATLLIMGLATVTVGLVPTTVAIGAAAPLILTTMRLLQG
MMAR_4238|M.marinum_M FGDRLGRKKTLVATLLIMALSTVTVGVVPSTATIGVSAPLILVALRLLQG
MUL_0949|M.ulcerans_Agy99 FGDRLGRKKTLVATLLIMALSTVTVGVVPSTATIGVSAPLILVALRLLQG
**: ***: * :::::. * :* :*: :* ** :* :*.:**
Mflv_1471|M.gilvum_PYR-GCK FAVGGEWGGAVLLVAEHSPAKERGFWASWPQAAVPVGNMLATVVLLVLTG
Mvan_5300|M.vanbaalenii_PYR-1 FAVGGEWGGAVLLVAEHSPNKERGFWASWPQAAVPVGNMLATVVLLVLTG
TH_4243|M.thermoresistible__bu FAVGGEWGGAVLLVAEHSPNDRRAFWSSWPQAAVPVGNMLATVVLLVLTT
MSMEG_6027|M.smegmatis_MC2_155 FAVGGEWGGAVLLVAEHSPNPSRGFWASWPQAGVPVGNMLATIVLLVLNG
MAB_4485|M.abscessus_ATCC_1997 FAVGGEWGGAVLLVAEHSPDSQRGFWASWPQAAVPLGNLLATLVLLTLSW
MAV_4627|M.avium_104 FALGGEWGGAVLLAVEHSPGDRRGRYGAVPQVGLALGLALGTGIFAFLQI
Mb1232|M.bovis_AF2122/97 FAVGGEWAGSALLSAEYAPASKRGWYGMFTVVGGGIALVLTSLTFLGVNY
Rv1200|M.tuberculosis_H37Rv FAVGGEWAGSALLSAEYAPASKRGWYGMFTVVGGGIALVLTSLTFLGVNY
MMAR_4238|M.marinum_M FAVGGEWAGSALLSIESAPAHKRGYYGMFTVLGGGVALVVSGLTFLGVNY
MUL_0949|M.ulcerans_Agy99 FAVGGEWAGSALLSIESAPAHKRGYYGMFTVLGGGVALVVSGLTFLGVNY
**:****.*:.** * :* *. :. . . :. : : :
Mflv_1471|M.gilvum_PYR-GCK VLPEA--AFMSWGWRIAFWLSAVVVLIGYYIRTKVTDAPIFVAAQEEVER
Mvan_5300|M.vanbaalenii_PYR-1 TLSND--AFLSWGWRVAFWLSAVVVLVGYYIRTKVTDAPIFVAAQEEVER
TH_4243|M.thermoresistible__bu TLPES--AFLSWGWRVAFWLSAVVVLIGYYIRTKVSDAPIFLAVQQEVEQ
MSMEG_6027|M.smegmatis_MC2_155 LLSDA--AFLSWGWRVAFWLSAVVVLIGYYIRTKVTDAPIFVAAQQEAER
MAB_4485|M.abscessus_ATCC_1997 TLSDS--AFMAWGWRVGFWLSVIIVAIGYYIRTRISDAPIFHEARKEIER
MAV_4627|M.avium_104 VLGPA--RFLSYGWRIGFLLSVLLVAIGIVVRLRVEETPAFRELQ-DLQA
Mb1232|M.bovis_AF2122/97 TIGESSPTFMQWGWRIPFLVSAALIAVALYVRFNIDETPVFAR--ERADE
Rv1200|M.tuberculosis_H37Rv TIGESSPTFMQWGWRIPFLVSAALIAVALYVRFNIDETPVFAR--ERADE
MMAR_4238|M.marinum_M TIGESSSAFLQWGWRVPFLLSALLIAFALYVRLEINETPVFARAMAQADD
MUL_0949|M.ulcerans_Agy99 TIGESSSALLQWGWRVPFLLSALLIAFALYVRLEINETPVFARAMAQADD
: :: :***: * :*. :: .. :* .: ::* * :
Mflv_1471|M.gilvum_PYR-GCK TK---AVSYGVVEVLKRYPRGVFTAMGLRFAENIMYYLVVTFSIVYLKNH
Mvan_5300|M.vanbaalenii_PYR-1 VK---SVSYGVVEVLKRYPRGVFTAMGLRFAENIMYYLVVTFSIVYLKTH
TH_4243|M.thermoresistible__bu AR---STSYGVVEVLRRYPRGVLTAMGLRFAENIMYYLVVTFSITYLKVH
MSMEG_6027|M.smegmatis_MC2_155 IK---ASSFNAIEVLKLYPRGVITAMGLRFGENIMYYLVVTFTITYLAQR
MAB_4485|M.abscessus_ATCC_1997 NK---ASSYGVIEVFRRYPRGVFTAMGLRVAENILYYMVVTFSITYLKTQ
MAV_4627|M.avium_104 AS---TVPIRDILRERRSRRNTVLGLLSRWAEGSAFNTWGVFAISYATGA
Mb1232|M.bovis_AF2122/97 KTRLGPAETPIAQVLRRQRREIVLAAGSAVCCFGFVYLASTYLASYAQTR
Rv1200|M.tuberculosis_H37Rv KTRLGPAETPIAQVLRRQRREIVLAAGSAVCCFGFVYLASTYLASYAQTR
MMAR_4238|M.marinum_M QESTAAARAPLAAVLCRQRREIVLAAGAMLAAFGCLYLASTFLPSYAQLH
MUL_0949|M.ulcerans_Agy99 QESTAAARAPLAAVLCRQRREIVLAAGAMLAAFGCLYLASTFLPSYAQLH
. * . . .: *
Mflv_1471|M.gilvum_PYR-GCK VGADTSDILWWLLAAHAVHFLVVPQVGRLSDRFGRRPVYIVGAILAATWG
Mvan_5300|M.vanbaalenii_PYR-1 VGADTSDILWWLLAAHAVHFLVVPQVGRLADRFGRRPVYIAGAMLAATWG
TH_4243|M.thermoresistible__bu VGADTSDILWYLMAAHAVHFVAIPTVGRLADEFGRRPVYLVGTLAAGAWG
MSMEG_6027|M.smegmatis_MC2_155 VHVDTNRILWYLLIAHAVHFLAVPTVGRLSDRFGRRPVYFLGAVLAMVWG
MAB_4485|M.abscessus_ATCC_1997 LHMDTRRILLLLLIAHVVQAIALPIVGRYTDIAGRRAPYALGALLSAGWG
MAV_4627|M.avium_104 LGLNRVSVLIAVTIAALLMAVLLPVSGVLTDRFGARRVYLAGIACYGLAA
Mb1232|M.bovis_AF2122/97 LGYSRGSILFDSVLGGLLCIVFTALSSALCDQLGRRRVLLAGWAVALPWS
Rv1200|M.tuberculosis_H37Rv LGYSRGSILFDSVLGGLLCIVFTALSSALCDQLGRRRVLLAGWAVALPWS
MMAR_4238|M.marinum_M LGYSRNLVLLIGVLGGLVCIGFVALSAILCDRFGRRRVMLVGWAVGLFWS
MUL_0949|M.ulcerans_Agy99 LGYSRNLVLLIGVLGGLVCIGFVALSAILCDRFGRRRVMLVGWAVGLFWS
: . :* . : . . * * * * .
Mflv_1471|M.gilvum_PYR-GCK FFAFPMMNTGSYLLIMGAVILGL-MIHALMYAPQPAIMAEMFPTRMRYSG
Mvan_5300|M.vanbaalenii_PYR-1 FFAFPMMNSGDYLLILGAVILGL-MIHALMYAPQPAIMAEMFPTRMRYSG
TH_4243|M.thermoresistible__bu FIAFPMMNSANYVIITGAVVLGL-IAHAFMYAPQPALMAEMFPTRMRYSG
MSMEG_6027|M.smegmatis_MC2_155 FFAYPMMDTGQYAIVTLAVILGL-VIHALMYAPQPAIMAEMFPTRMRYSG
MAB_4485|M.abscessus_ATCC_1997 FIAFPMFNTRNEWVILTAIVIGL-LVHSLMFAGQPAIMAEMFPTRMRYSG
MAV_4627|M.avium_104 FPAFALFGTKKLLWFGLAMVIVFGVVHALFYGAQGTLYSALYPTNTRYTG
Mb1232|M.bovis_AF2122/97 LLVMPLIDSGSPSLFAVAVVGMY-AIGGFGFGPTASFIPELFATSYRYTG
Rv1200|M.tuberculosis_H37Rv LLVMPLIDSGSPSLFAVAVVGMY-AIGGFGFGPTASFIPELFATSYRYTG
MMAR_4238|M.marinum_M PLVMPLIGSGDTVGFTVALLGLY-AVAASGFGPAASLIPELFATRYRYTG
MUL_0949|M.ulcerans_Agy99 PLVMPLIGSGDTVGFTVALLGLY-AVAASGFGPAASLIPELFATRYRYTG
. .::.: . . *:: . :. :: . ::.* **:*
Mflv_1471|M.gilvum_PYR-GCK VSLGYQVTSIVAGSLAPAIATWLLDKFGTWVPIAL-YLAGAAVITLVAAW
Mvan_5300|M.vanbaalenii_PYR-1 VSLGYQVTSIVAGSLAPAIATWLLDRFGTWVPIAV-YLAGAAVITLVAAW
TH_4243|M.thermoresistible__bu VSVGYQVTAIVAGSMAPIIAVRLLDVYSSAVPIAL-YLAGAAVVTLIALA
MSMEG_6027|M.smegmatis_MC2_155 VSLGYQVTSIVAGSLAPIIAVWLLKTFDSSVPIAI-YLALAALVTLVSVI
MAB_4485|M.abscessus_ATCC_1997 VSVGYQVTSIFAGSLAPVIGTALLGRYHSWVPVAV-YLAAVAPITLFAVW
MAV_4627|M.avium_104 LSFVYQFSGVYASGVTPMILTALIAALGGAPWLACGYLVATAVISVLATA
Mb1232|M.bovis_AF2122/97 SALAANLAGVAGGALPPVIAGALVATYGSWAIGVM--LAILALISLVCTY
Rv1200|M.tuberculosis_H37Rv SALAANLAGVAGGALPPVIAGALVATYGSWAIGVM--LAILALISLVCTY
MMAR_4238|M.marinum_M TALALNVAGIVGGAAPPLIAGTLLASYGSSAVGLM--MTALVAASLLCTY
MUL_0949|M.ulcerans_Agy99 TALALNVAGIVGGAAPPLIAGTLLASYGSSAVGLM--MTALVAASLLCTY
:. :.:.: ... .* * *: :. . ::..
Mflv_1471|M.gilvum_PYR-GCK FTRETKGIDLHALDVADREQLEKAGIV-----------------------
Mvan_5300|M.vanbaalenii_PYR-1 FTRETNGIDLHSLDVADREQLAKAGIV-----------------------
TH_4243|M.thermoresistible__bu FTRETNGIDLAGVDRADAEESARXXPTTTDRPAQCPGVPVCRRLRSSGPR
MSMEG_6027|M.smegmatis_MC2_155 AARETKGIDLADIDAADVERVRA---------------------------
MAB_4485|M.abscessus_ATCC_1997 SLPETRGSSLHELDAADRART-----------------------------
MAV_4627|M.avium_104 LIRDR---DLYL--------------------------------------
Mb1232|M.bovis_AF2122/97 RLPETAGSALVSR-------------------------------------
Rv1200|M.tuberculosis_H37Rv RLPETAGSALVSR-------------------------------------
MMAR_4238|M.marinum_M LLPETAGAPLTAA-------------------------------------
MUL_0949|M.ulcerans_Agy99 LLPETAGAPLTAA-------------------------------------
: *
Mflv_1471|M.gilvum_PYR-GCK --------------------------------------------------
Mvan_5300|M.vanbaalenii_PYR-1 --------------------------------------------------
TH_4243|M.thermoresistible__bu ARRRTERCWRTPGIQPAVRPTRSPTPGPSAARTRRAAPVTRSAGSAATIR
MSMEG_6027|M.smegmatis_MC2_155 --------------------------------------------------
MAB_4485|M.abscessus_ATCC_1997 --------------------------------------------------
MAV_4627|M.avium_104 --------------------------------------------------
Mb1232|M.bovis_AF2122/97 --------------------------------------------------
Rv1200|M.tuberculosis_H37Rv --------------------------------------------------
MMAR_4238|M.marinum_M --------------------------------------------------
MUL_0949|M.ulcerans_Agy99 --------------------------------------------------
Mflv_1471|M.gilvum_PYR-GCK ---
Mvan_5300|M.vanbaalenii_PYR-1 ---
TH_4243|M.thermoresistible__bu RSR
MSMEG_6027|M.smegmatis_MC2_155 ---
MAB_4485|M.abscessus_ATCC_1997 ---
MAV_4627|M.avium_104 ---
Mb1232|M.bovis_AF2122/97 ---
Rv1200|M.tuberculosis_H37Rv ---
MMAR_4238|M.marinum_M ---
MUL_0949|M.ulcerans_Agy99 ---