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M. thermoresistible (build 8) TH_3346 (-)

annotation: short-chain dehydrogenase/reductase SDR
coordinates: 279151 - 279915
length: 255

aa seq not available

Operon Prediction Model: Genebank

Paralogs

species id gene e-value identity (len) annotation
M. thermoresistible (build 8) TH_3346 - - 100% (255) short-chain dehydrogenase/reductase SDR
M. thermoresistible (build 8) TH_1987 - 4e-57 48.44% (256) 3-Hydroxyacyl-CoA dehydrogenase
M. thermoresistible (build 8) TH_1570 - 1e-53 45.74% (258) 3-Hydroxyacyl-CoA dehydrogenase

Closest Orthologs (e-value cutoff: 1e-4)

species id gene e-value identity (len) annotation
M. bovis AF2122 / 97 Mb1176 - 2e-54 47.66% (256) short-chain type dehydrogenase/reductase
M. gilvum PYR-GCK Mflv_3163 - 6e-57 43.63% (259) short-chain dehydrogenase/reductase SDR
M. tuberculosis H37Rv Rv1144 - 2e-54 47.66% (256) short-chain type dehydrogenase/reductase
M. leprae Br4923 MLBr_01807 fabG1 1e-13 29.51% (244) 3-oxoacyl-
M. abscessus ATCC 19977 MAB_0368 - 1e-64 50.77% (260) Short-chain dehydrogenase/reductas
M. marinum M MMAR_4307 - 3e-54 46.90% (258) short-chain type dehydrogenase/reductase
M. avium 104 MAV_2552 - 8e-72 55.16% (252) 3-hydroxyacyl-CoA dehydrogenase type-2
M. smegmatis MC2 155 MSMEG_4871 - 1e-128 88.58% (254) 3-hydroxyacyl-CoA dehydrogenase type-2
M. ulcerans Agy99 MUL_0987 - 9e-55 46.90% (258) short-chain type dehydrogenase/reductase
M. vanbaalenii PYR-1 Mvan_4251 - 1e-129 89.76% (254) short-chain dehydrogenase/reductase SDR

CLUSTAL 2.0.9 multiple sequence alignment


TH_3346|M.thermoresistible__bu      ---------------MQIA---GSAALVVGGAGGLGEATVRRLHAAGAKV
Mvan_4251|M.vanbaalenii_PYR-1       ---------------MQIA---GSSALVVGGAGGLGEATVRRLHDAGAKV
MSMEG_4871|M.smegmatis_MC2_155      ---------------MQIA---GTSALVVGGTGGLGEATVRRLHGAGAKV
MAV_2552|M.avium_104                ---------------MTVAKFDGASAIVSGGAGGLGEATVRRLHADGLGV
Mb1176|M.bovis_AF2122/97            ---------------MKTK---DAVAVVTGGASGLGLATTKRLLDAGAQV
Rv1144|M.tuberculosis_H37Rv         ---------------MKTK---DAVAVVTGGASGLGLATTKRLLDAGAQV
MMAR_4307|M.marinum_M               ---------------MEIR---DAVAVVTGGASGLGLATTKRLLDAGAQV
MUL_0987|M.ulcerans_Agy99           ---------------MEIR---DAVAVVTGGASGLGLATTKRLLDAGAQV
Mflv_3163|M.gilvum_PYR-GCK          MVRRVPRNGLFYTSAVDVN---GTSAIVTGGASGIGAATARLLASQGARV
MAB_0368|M.abscessus_ATCC_1997      ---------------MDIN---GVSAIVTGGASGLGAATARLLAAQGAKV
MLBr_01807|M.leprae_Br4923          --MTDAAAKVSAAPGRGKPAFVSRSILVTGGNRGIGLAVARRLVADGHRV
                                                          .   :* **  *:* *..: *   *  *

TH_3346|M.thermoresistible__bu      VVADLADERGGELEKELG--VRYVRTDATSEQDVLAAIAEAESLG-PLRI
Mvan_4251|M.vanbaalenii_PYR-1       VIADLADDKGRQLESELG--VRYVRTDATSEESVNAAITEAESLG-PLRI
MSMEG_4871|M.smegmatis_MC2_155      VVADVADDKGAALEKELG--IRYVRTDATSEESVLAAIAEAESLA-PLRI
MAV_2552|M.avium_104                VIADLAADKGKALADELGSGALFVSTDVTSDESVQGAIEQANQLG-RLRY
Mb1176|M.bovis_AF2122/97            VVVDLR---GDDVVGGLGDRARFAQADVTDEAAVSNALELADSLG-PVRV
Rv1144|M.tuberculosis_H37Rv         VVVDLR---GDDVVGGLGDRARFAQADVTDEAAVSNALELADSLG-PVRV
MMAR_4307|M.marinum_M               VVLDIR---GEDVVADLGDRARFAAADVTDEAAVASALDLAETMG-TLRI
MUL_0987|M.ulcerans_Agy99           VVLDIR---GEDVVADLGDRARFAAADVTDEAAVASALDLAETMG-TLRI
Mflv_3163|M.gilvum_PYR-GCK          VIADLQAERGQELAHEIGG--AYVSVDVTDTAQIEDAVNTAIDLG-PLRA
MAB_0368|M.abscessus_ATCC_1997      VIADVQDEKGEALAKELGG--AFVHTDVTSEADGIAAVDAAKELG-PVRV
MLBr_01807|M.leprae_Br4923          AVTHRAS--------VVPDWFFGVECDVTDNDAIGAAFKAVEEHQGPVEV
                                    .: .            :      .  *.*.      *.  .      :. 

TH_3346|M.thermoresistible__bu      SVDTHGGPAGGGRLVGKDGSPLG---LEAFETTIKYYLTAVFNIMRLTAA
Mvan_4251|M.vanbaalenii_PYR-1       SVDTHGGPAGGGRLVGKDGSPLS---MEAFETTIKFYLTAVFNIMRLSAA
MSMEG_4871|M.smegmatis_MC2_155      SVDTHGGPASGGRLVGKDGSPLD---LDGFKKTIEFYLTAVFNVMRLTAA
MAV_2552|M.avium_104                AVVAHGGFGVAQRIVQRDGSPAD---MAAFTKTINLYLNGTYNLTRLVAA
Mb1176|M.bovis_AF2122/97            VVNCAG-TGNAIRVLSRDGVFP----LAAFRKIVDINLVGTFNVLRLGAE
Rv1144|M.tuberculosis_H37Rv         VVNCAG-TGNAIRVLSRDGVFP----LAAFRKIVDINLVGTFNVLRLGAE
MMAR_4307|M.marinum_M               VVNCAG-TGNAIRVLSRDGVFP----LAAFRKIVDINLVGSFNVLRLAAE
MUL_0987|M.ulcerans_Agy99           VVNCAG-TGNAIRVLSRDGVFS----LAAFRKIVDINLVGSFNVLRLAAE
Mflv_3163|M.gilvum_PYR-GCK          LVNSAG-IGWAQRTIGKDGEFASAHNLDAYKKVLAINLVGTFDCIRLAAT
MAB_0368|M.abscessus_ATCC_1997      LINCAG-VGWPGRTIGKDGQYASAHSLDIFSKVIGINLIGSFNLIRLAAT
MLBr_01807|M.leprae_Br4923          LVANAG--ITSDMLIMRMSE-------EQFQKVIDVNLTGVFRVAKLASR
                                     :   *        : : .          : . :   * . :   :* : 

TH_3346|M.thermoresistible__bu      AIGRTEPLEE--GGRGVIVNTASIAGYEGQIGQLPYAAAKGGVIGMTLNA
Mvan_4251|M.vanbaalenii_PYR-1       AIAKTEPLEE--GGRGVIVNTASVAGYEGQIGQLPYSAAKGGVIGMTLVA
MSMEG_4871|M.smegmatis_MC2_155      AIARTEPLEE--GGRGVIVNTASIAGYEGQIGQLPYAAAKGGVLGMTLVA
MAV_2552|M.avium_104                AVAAAEPRED--GERGAIVMTASVAGYEGQIGQTAYAAAKAGVIGLTIAA
Mb1176|M.bovis_AF2122/97            RIAKTEPIG---EERGVIINTASVAAFDGQIGQAAYSASKGGVVGMTLPI
Rv1144|M.tuberculosis_H37Rv         RIAKTEPIG---EERGVIINTASVAAFDGQIGQAAYSASKGGVVGMTLPI
MMAR_4307|M.marinum_M               RIAKTEPVGPNAEERGVIINTASVAAFDGQIGQAAYSASKGGVVGMTLPI
MUL_0987|M.ulcerans_Agy99           RIAKTEPVGPNAEERGVIINTASVAAFDGQIGQAAYSASKGGVVGMTLPI
Mflv_3163|M.gilvum_PYR-GCK          AMSRLD-LTES-GERGAIVNMTSVAAFDGQIGQAAYSSSKGGVVGLTLPV
MAB_0368|M.abscessus_ATCC_1997      AISQEEPVDEF-GERGAIVNTASVAAFDGQIGQAAYSASKGGIVGMTLPI
MLBr_01807|M.leprae_Br4923          NMIKQR--------FGRYIFMGSVVGLSGVPGQANYAASKSGLIGMARSL
                                     :             *  :   *:.. .*  **  *:::*.*::*::   

TH_3346|M.thermoresistible__bu      ARDLSPLGIRVVTIAPGTINTPAYGQHA--DQLEAYWGPQVPFPKRMGRS
Mvan_4251|M.vanbaalenii_PYR-1       ARDLSPLGIRVVTIAPGTINTPAYGKAA--DQLEQYWGPQVPFPKRMGRS
MSMEG_4871|M.smegmatis_MC2_155      ARDLSPLGIRVVTIAPGTINTPAYGQAA--DQLEEYWGPQVPFPKRMGRS
MAV_2552|M.avium_104                ARDLSSVGIRVNTIAPGTMKTPIMESVG--EEAIAKFAANIPFPKRLGTP
Mb1176|M.bovis_AF2122/97            ARDLASKLIRVVTIAPGLFDTPLLASLP--AEAKASLGQQVPHPSRLGNP
Rv1144|M.tuberculosis_H37Rv         ARDLASKLIRVVTIAPGLFDTPLLASLP--AEAKASLGQQVPHPSRLGNP
MMAR_4307|M.marinum_M               ARDLASHRIRVMTIAPGLFDTPLLASLP--EEARASLGKQVPHPSRLGSP
MUL_0987|M.ulcerans_Agy99           ARDLASHRIRVMTIAPGLFDTPLLASLP--EEARASLGKQVPHPSRLGNP
Mflv_3163|M.gilvum_PYR-GCK          ARDLAAVGIRVNTVAPGLIDTPIYGEGPDSEAFKAKLGESVLYPRRLGKP
MAB_0368|M.abscessus_ATCC_1997      ARDLSVVGIRVNTIAPGLIDTPIYGEGESAQQFKDRLAPNVLYPQRLGNP
MLBr_01807|M.leprae_Br4923          ARELGSRSITANVVAPGFIDTEMTRAMD--SKYQEAALQAIPLG-RIGAV
                                    **:*.   * . .:*** :.*                   :    *:*  

TH_3346|M.thermoresistible__bu      TEYAQLAQSIIEN--DYLNGEIIRLDGALRFPPK
Mvan_4251|M.vanbaalenii_PYR-1       TEYAQLAQSVIEN--DYLNGEVIRLDGALRFPPK
MSMEG_4871|M.smegmatis_MC2_155      TEYAQLAQSIVEN--DYLNGEVIRLDGALRFPPK
MAV_2552|M.avium_104                AEYADAATFLLSN--GYVNGEVMRLDGAQRFTPK
Mb1176|M.bovis_AF2122/97            DEYGALVLHIIEN--PMLNGEVIRLDGAIRMAPR
Rv1144|M.tuberculosis_H37Rv         DEYGALVLHIIEN--PMLNGEVIRLDGAIRMAPR
MMAR_4307|M.marinum_M               DEYGALAVHIIEN--PMLNGEVIRLDGAIRMAPR
MUL_0987|M.ulcerans_Agy99           DEYGALAVHIIEN--PMLNGEVIRLDGAIRMAPR
Mflv_3163|M.gilvum_PYR-GCK          EELASMVVELLTN--SYMNAEVVRVDGGIRMPPK
MAB_0368|M.abscessus_ATCC_1997      EEFASLALELVTN--SYMNAETIRIDGGARLQPK
MLBr_01807|M.leprae_Br4923          EEIAGAVSFLASEDAGYISGAVIPVDGGLGMGH-
                                     * .  .  :  :    :..  : :**.  :

species	id	gene	e-value	identity (len)	annotation
M. thermoresistible (build 8)	TH_3346	-	-	100% (255)	short-chain dehydrogenase/reductase SDR
M. thermoresistible (build 8)	TH_1987	-	4e-57	48.44% (256)	3-Hydroxyacyl-CoA dehydrogenase
M. thermoresistible (build 8)	TH_1570	-	1e-53	45.74% (258)	3-Hydroxyacyl-CoA dehydrogenase