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MQIAGTSALVVGGTGGLGEATVRRLHGAGAKVVVADVADDKGAALEKELGIRYVRTDATSEESVLAAIAE AESLAPLRISVDTHGGPASGGRLVGKDGSPLDLDGFKKTIEFYLTAVFNVMRLTAAAIARTEPLEEGGRG VIVNTASIAGYEGQIGQLPYAAAKGGVLGMTLVAARDLSPLGIRVVTIAPGTINTPAYGQAADQLEEYWG PQVPFPKRMGRSTEYAQLAQSIVENDYLNGEVIRLDGALRFPPK
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. smegmatis MC2 155 | MSMEG_4871 | - | - | 100% (254) | 3-hydroxyacyl-CoA dehydrogenase type-2 |
| M. smegmatis MC2 155 | MSMEG_5183 | - | 1e-60 | 51.16% (258) | 3-hydroxyacyl-CoA dehydrogenase |
| M. smegmatis MC2 155 | MSMEG_0216 | - | 7e-60 | 45.56% (259) | 3-hydroxyacyl-CoA dehydrogenase |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb1176 | - | 4e-53 | 46.67% (255) | short-chain type dehydrogenase/reductase |
| M. gilvum PYR-GCK | Mflv_2127 | - | 6e-57 | 49.61% (256) | short-chain dehydrogenase/reductase SDR |
| M. tuberculosis H37Rv | Rv1144 | - | 4e-53 | 46.67% (255) | short-chain type dehydrogenase/reductase |
| M. leprae Br4923 | MLBr_01807 | fabG1 | 4e-16 | 29.80% (255) | 3-oxoacyl- |
| M. abscessus ATCC 19977 | MAB_0368 | - | 2e-65 | 51.54% (260) | Short-chain dehydrogenase/reductas |
| M. marinum M | MMAR_4307 | - | 2e-53 | 46.12% (258) | short-chain type dehydrogenase/reductase |
| M. avium 104 | MAV_1812 | - | 3e-74 | 56.86% (255) | 3-hydroxyacyl-CoA dehydrogenase type-2 |
| M. thermoresistible (build 8) | TH_3346 | - | 1e-128 | 88.58% (254) | PUTATIVE short-chain dehydrogenase/reductase SDR |
| M. ulcerans Agy99 | MUL_0987 | - | 6e-54 | 46.12% (258) | short-chain type dehydrogenase/reductase |
| M. vanbaalenii PYR-1 | Mvan_4251 | - | 1e-128 | 88.19% (254) | short-chain dehydrogenase/reductase SDR |
CLUSTAL 2.0.9 multiple sequence alignment
TH_3346|M.thermoresistible__bu ----------------MQIAGSAALVVGGAGGLGEATVRRLHAAGAKVVV
Mvan_4251|M.vanbaalenii_PYR-1 ----------------MQIAGSSALVVGGAGGLGEATVRRLHDAGAKVVI
MSMEG_4871|M.smegmatis_MC2_155 ----------------MQIAGTSALVVGGTGGLGEATVRRLHGAGAKVVV
MAV_1812|M.avium_104 -------------MTIKQFEGASAIVSGGAGGLGEATVRRLHADGLGVVI
MMAR_4307|M.marinum_M ----------------MEIRDAVAVVTGGASGLGLATTKRLLDAGAQVVV
MUL_0987|M.ulcerans_Agy99 ----------------MEIRDAVAVVTGGASGLGLATTKRLLDAGAQVVV
Mb1176|M.bovis_AF2122/97 ----------------MKTKDAVAVVTGGASGLGLATTKRLLDAGAQVVV
Rv1144|M.tuberculosis_H37Rv ----------------MKTKDAVAVVTGGASGLGLATTKRLLDAGAQVVV
Mflv_2127|M.gilvum_PYR-GCK ----------------MEIKDAAAVVTGGASGLGLATTKRLLDRGASVVV
MAB_0368|M.abscessus_ATCC_1997 ----------------MDINGVSAIVTGGASGLGAATARLLAAQGAKVVI
MLBr_01807|M.leprae_Br4923 MTDAAAKVSAAPGRGKPAFVSRSILVTGGNRGIGLAVARRLVADGHRVAV
. :* ** *:* *..: * * *.:
TH_3346|M.thermoresistible__bu ADLADERGGELEKELG--VRYVRTDATSEQDVLAAIAEAESLG-PLRISV
Mvan_4251|M.vanbaalenii_PYR-1 ADLADDKGRQLESELG--VRYVRTDATSEESVNAAITEAESLG-PLRISV
MSMEG_4871|M.smegmatis_MC2_155 ADVADDKGAALEKELG--IRYVRTDATSEESVLAAIAEAESLA-PLRISV
MAV_1812|M.avium_104 ADLAAEKGKALADELGNRAEFVSTNVTSEDSVLAAIEAANQLG-RLRYAV
MMAR_4307|M.marinum_M LDIR---GEDVVADLGDRARFAAADVTDEAAVASALDLAETMG-TLRIVV
MUL_0987|M.ulcerans_Agy99 LDIR---GEDVVADLGDRARFAAADVTDEAAVASALDLAETMG-TLRIVV
Mb1176|M.bovis_AF2122/97 VDLR---GDDVVGGLGDRARFAQADVTDEAAVSNALELADSLG-PVRVVV
Rv1144|M.tuberculosis_H37Rv VDLR---GDDVVGGLGDRARFAQADVTDEAAVSNALELADSLG-PVRVVV
Mflv_2127|M.gilvum_PYR-GCK IDLK---GEDVVAELGPRAKFVEANVTDPEQVAAALDAAEEFG-PLRINV
MAB_0368|M.abscessus_ATCC_1997 ADVQDEKGEALAKELGG--AFVHTDVTSEADGIAAVDAAKELG-PVRVLI
MLBr_01807|M.leprae_Br4923 THRAS--------VVPDWFFGVECDVTDNDAIGAAFKAVEEHQGPVEVLV
. : . :.*. *. .. :. :
TH_3346|M.thermoresistible__bu DTHGGPAGGGRLVGKDGSPLG---LEAFETTIKYYLTAVFNIMRLTAAAI
Mvan_4251|M.vanbaalenii_PYR-1 DTHGGPAGGGRLVGKDGSPLS---MEAFETTIKFYLTAVFNIMRLSAAAI
MSMEG_4871|M.smegmatis_MC2_155 DTHGGPASGGRLVGKDGSPLD---LDGFKKTIEFYLTAVFNVMRLTAAAI
MAV_1812|M.avium_104 VAHGGFGVAQRIVQRDGSPAD---MGGFTKTIDLYLNGTYNVARLVAASI
MMAR_4307|M.marinum_M NCAG-TGNAIRVLSRDGVFP----LAAFRKIVDINLVGSFNVLRLAAERI
MUL_0987|M.ulcerans_Agy99 NCAG-TGNAIRVLSRDGVFS----LAAFRKIVDINLVGSFNVLRLAAERI
Mb1176|M.bovis_AF2122/97 NCAG-TGNAIRVLSRDGVFP----LAAFRKIVDINLVGTFNVLRLGAERI
Rv1144|M.tuberculosis_H37Rv NCAG-TGNAIRVLSRDGVFP----LAAFRKIVDINLVGTFNVLRLGAERI
Mflv_2127|M.gilvum_PYR-GCK NCAG-IGNAIKTLSKDGPFP----LDGFTKVIQVNLIGTFNVLRLAAERM
MAB_0368|M.abscessus_ATCC_1997 NCAG-VGWPGRTIGKDGQYASAHSLDIFSKVIGINLIGSFNLIRLAATAI
MLBr_01807|M.leprae_Br4923 ANAGITSDMLIMRMSE---------EQFQKVIDVNLTGVFRVAKLASRNM
* . : * . : * . :.: :* : :
TH_3346|M.thermoresistible__bu GRTEPLE--EGGRGVIVNTASIAGYEGQIGQLPYAAAKGGVIGMTLNAAR
Mvan_4251|M.vanbaalenii_PYR-1 AKTEPLE--EGGRGVIVNTASVAGYEGQIGQLPYSAAKGGVIGMTLVAAR
MSMEG_4871|M.smegmatis_MC2_155 ARTEPLE--EGGRGVIVNTASIAGYEGQIGQLPYAAAKGGVLGMTLVAAR
MAV_1812|M.avium_104 AAAEPRE--NGERGALVLTASIAGYEGQIGQTAYAAAKAGVIGLTIAAAR
MMAR_4307|M.marinum_M AKTEPVGPNAEERGVIINTASVAAFDGQIGQAAYSASKGGVVGMTLPIAR
MUL_0987|M.ulcerans_Agy99 AKTEPVGPNAEERGVIINTASVAAFDGQIGQAAYSASKGGVVGMTLPIAR
Mb1176|M.bovis_AF2122/97 AKTEPIG---EERGVIINTASVAAFDGQIGQAAYSASKGGVVGMTLPIAR
Rv1144|M.tuberculosis_H37Rv AKTEPIG---EERGVIINTASVAAFDGQIGQAAYSASKGGVVGMTLPIAR
Mflv_2127|M.gilvum_PYR-GCK AKQEPIN---GERGVIINTASVAAFEGQIGQAAYSASKGGVVGMTLPIAR
MAB_0368|M.abscessus_ATCC_1997 SQEEPVD-EFGERGAIVNTASVAAFDGQIGQAAYSASKGGIVGMTLPIAR
MLBr_01807|M.leprae_Br4923 IKQ--------RFGRYIFMGSVVGLSGVPGQANYAASKSGLIGMARSLAR
* : .*:.. .* ** *:*:*.*::*:: **
TH_3346|M.thermoresistible__bu DLSPLGIRVVTIAPGTINTPAYGQ--HADQLEAYWGPQVPFPKRMGRSTE
Mvan_4251|M.vanbaalenii_PYR-1 DLSPLGIRVVTIAPGTINTPAYGK--AADQLEQYWGPQVPFPKRMGRSTE
MSMEG_4871|M.smegmatis_MC2_155 DLSPLGIRVVTIAPGTINTPAYGQ--AADQLEEYWGPQVPFPKRMGRSTE
MAV_1812|M.avium_104 DLSSAGIRVNTIAPGTMKTPIMES--VGEEALAKFAANIPFPKRLGTPDE
MMAR_4307|M.marinum_M DLASHRIRVMTIAPGLFDTPLLAS--LPEEARASLGKQVPHPSRLGSPDE
MUL_0987|M.ulcerans_Agy99 DLASHRIRVMTIAPGLFDTPLLAS--LPEEARASLGKQVPHPSRLGNPDE
Mb1176|M.bovis_AF2122/97 DLASKLIRVVTIAPGLFDTPLLAS--LPAEAKASLGQQVPHPSRLGNPDE
Rv1144|M.tuberculosis_H37Rv DLASKLIRVVTIAPGLFDTPLLAS--LPAEAKASLGQQVPHPSRLGNPDE
Mflv_2127|M.gilvum_PYR-GCK DLSREFIRVCTIAPGLFKTPLLGS--LPEEAQASLGKQVPHPARLGDPDE
MAB_0368|M.abscessus_ATCC_1997 DLSVVGIRVNTIAPGLIDTPIYGEGESAQQFKDRLAPNVLYPQRLGNPEE
MLBr_01807|M.leprae_Br4923 ELGSRSITANVVAPGFIDTEMTRA---MDSKYQEAALQAIPLGRIGAVEE
:*. * . .:*** :.* . . : *:* *
TH_3346|M.thermoresistible__bu YAQLAQSIIEN--DYLNGEIIRLDGALRFPPK
Mvan_4251|M.vanbaalenii_PYR-1 YAQLAQSVIEN--DYLNGEVIRLDGALRFPPK
MSMEG_4871|M.smegmatis_MC2_155 YAQLAQSIVEN--DYLNGEVIRLDGALRFPPK
MAV_1812|M.avium_104 FADAAAFLLTN--GYINGEVMRLDGAQRFTPK
MMAR_4307|M.marinum_M YGALAVHIIEN--PMLNGEVIRLDGAIRMAPR
MUL_0987|M.ulcerans_Agy99 YGALAVHIIEN--PMLNGEVIRLDGAIRMAPR
Mb1176|M.bovis_AF2122/97 YGALVLHIIEN--PMLNGEVIRLDGAIRMAPR
Rv1144|M.tuberculosis_H37Rv YGALVLHIIEN--PMLNGEVIRLDGAIRMAPR
Mflv_2127|M.gilvum_PYR-GCK YGALAVHIVEN--PMLNGETIRLDGAIRMAPR
MAB_0368|M.abscessus_ATCC_1997 FASLALELVTN--SYMNAETIRIDGGARLQPK
MLBr_01807|M.leprae_Br4923 IAGAVSFLASEDAGYISGAVIPVDGGLGMGH-
. . : : :.. : :**. :