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M. thermoresistible (build 8) TH_1570 (-)

annotation: 3-Hydroxyacyl-CoA dehydrogenase
coordinates: 2957721 - 2958494
length: 258

aa seq not available

Operon Prediction Model: Genebank

Paralogs

species id gene e-value identity (len) annotation
M. thermoresistible (build 8) TH_1570 - - 100% (258) 3-Hydroxyacyl-CoA dehydrogenase
M. thermoresistible (build 8) TH_1987 - 5e-72 56.03% (257) 3-Hydroxyacyl-CoA dehydrogenase
M. thermoresistible (build 8) TH_3183 - 4e-58 47.67% (258) PUTATIVE short-chain dehydrogenase/reductase SDR

Closest Orthologs (e-value cutoff: 1e-4)

species id gene e-value identity (len) annotation
M. bovis AF2122 / 97 Mb1176 - 1e-72 58.33% (252) short-chain type dehydrogenase/reductase
M. gilvum PYR-GCK Mflv_2127 - 1e-74 57.59% (257) short-chain dehydrogenase/reductase SDR
M. tuberculosis H37Rv Rv1144 - 1e-72 58.33% (252) short-chain type dehydrogenase/reductase
M. leprae Br4923 MLBr_01807 fabG1 3e-21 31.87% (251) 3-oxoacyl-
M. abscessus ATCC 19977 MAB_0368 - 2e-62 48.85% (262) Short-chain dehydrogenase/reductas
M. marinum M MMAR_4307 - 7e-75 57.98% (257) short-chain type dehydrogenase/reductase
M. avium 104 MAV_1285 - 1e-72 56.54% (260) 3-hydroxyacyl-CoA dehydrogenase
M. smegmatis MC2 155 MSMEG_5183 - 3e-73 55.25% (257) 3-hydroxyacyl-CoA dehydrogenase
M. ulcerans Agy99 MUL_0987 - 1e-75 58.37% (257) short-chain type dehydrogenase/reductase
M. vanbaalenii PYR-1 Mvan_4577 - 1e-71 55.25% (257) short-chain dehydrogenase/reductase SDR

CLUSTAL 2.0.9 multiple sequence alignment


Mflv_2127|M.gilvum_PYR-GCK          ----------------MEIKDAAAVVTGGASGLGLATTKRLLDRGASVVV
Mvan_4577|M.vanbaalenii_PYR-1       ----------------MEIKDAVAVVTGGASGLGLATTKRLLDRGASVVV
MAV_1285|M.avium_104                ----------------MEIKDAVAVVTGGASGLGLATTKRLLDRGAQVVV
MSMEG_5183|M.smegmatis_MC2_155      ----------------MEIKDAVAVVTGGASGLGLATTKRLLDAGAQVVV
Mb1176|M.bovis_AF2122/97            ----------------MKTKDAVAVVTGGASGLGLATTKRLLDAGAQVVV
Rv1144|M.tuberculosis_H37Rv         ----------------MKTKDAVAVVTGGASGLGLATTKRLLDAGAQVVV
MMAR_4307|M.marinum_M               ----------------MEIRDAVAVVTGGASGLGLATTKRLLDAGAQVVV
MUL_0987|M.ulcerans_Agy99           ----------------MEIRDAVAVVTGGASGLGLATTKRLLDAGAQVVV
TH_1570|M.thermoresistible__bu      ----------------VNIDGASAIVTGGASGLGRATAQRLAEAGAHVVV
MAB_0368|M.abscessus_ATCC_1997      ----------------MDINGVSAIVTGGASGLGAATARLLAAQGAKVVI
MLBr_01807|M.leprae_Br4923          MTDAAAKVSAAPGRGKPAFVSRSILVTGGNRGIGLAVARRLVADGHRVAV
                                                        .   :****  *:* *.:: *   *  *.:

Mflv_2127|M.gilvum_PYR-GCK          IDLK---GEDVVAELGPRAKFVEANVTDPEQVAAALDAAEE-FGPLRINV
Mvan_4577|M.vanbaalenii_PYR-1       MDLR---GEEAVKELDARAKFVETNVTDPEQVAAALDAAEE-MGPLRIDV
MAV_1285|M.avium_104                IDLR---GEDAVRELGDRARFVQADVTDEAAVGKALDTAES-MGPLRINV
MSMEG_5183|M.smegmatis_MC2_155      IDLK---GEEVVAELGDRAKFVATDVTDEAGVTEALNVAES-LGPVRINV
Mb1176|M.bovis_AF2122/97            VDLR---GDDVVGGLGDRARFAQADVTDEAAVSNALELADS-LGPVRVVV
Rv1144|M.tuberculosis_H37Rv         VDLR---GDDVVGGLGDRARFAQADVTDEAAVSNALELADS-LGPVRVVV
MMAR_4307|M.marinum_M               LDIR---GEDVVADLGDRARFAAADVTDEAAVASALDLAET-MGTLRIVV
MUL_0987|M.ulcerans_Agy99           LDIR---GEDVVADLGDRARFAAADVTDEAAVASALDLAET-MGTLRIVV
TH_1570|M.thermoresistible__bu      VDLPGAAGNAVADDLGGSSVFVAADVTNAAQVQKAVDAAVE-RGPLRVLV
MAB_0368|M.abscessus_ATCC_1997      ADVQDEKGEALAKELGG--AFVHTDVTSEADGIAAVDAAKE-LGPVRVLI
MLBr_01807|M.leprae_Br4923          THRA--------SVVPDWFFGVECDVTDNDAIGAAFKAVEEHQGPVEVLV
                                     .            :      .  :**.      *.. .    *.:.: :

Mflv_2127|M.gilvum_PYR-GCK          NCAGIGNAIKTLSKDG----PFPLDGFTKVIQVNLIGTFNVLRLAAERMA
Mvan_4577|M.vanbaalenii_PYR-1       NCAGIGNAAKTLSKDG----PFPLDAFKKVVEVNLIGTFNVIRLAAERIA
MAV_1285|M.avium_104                NCAGIGNAIKTLSKDG----PFPLDAFKKVVGVNLIGTFNVLRLAAERIA
MSMEG_5183|M.smegmatis_MC2_155      NCAGIGNAIKTLSKNG----PFPLDGFRKVVEVNLIGTFNVIRLSAERIA
Mb1176|M.bovis_AF2122/97            NCAGTGNAIRVLSRDG----VFPLAAFRKIVDINLVGTFNVLRLGAERIA
Rv1144|M.tuberculosis_H37Rv         NCAGTGNAIRVLSRDG----VFPLAAFRKIVDINLVGTFNVLRLGAERIA
MMAR_4307|M.marinum_M               NCAGTGNAIRVLSRDG----VFPLAAFRKIVDINLVGSFNVLRLAAERIA
MUL_0987|M.ulcerans_Agy99           NCAGTGNAIRVLSRDG----VFSLAAFRKIVDINLVGSFNVLRLAAERIA
TH_1570|M.thermoresistible__bu      HCAGRGGPVRVLDRAGE---PGSLEEYVDIINVNLVGTFNTLRLAAAAMA
MAB_0368|M.abscessus_ATCC_1997      NCAGVGWPGRTIGKDGQYASAHSLDIFSKVIGINLIGSFNLIRLAATAIS
MLBr_01807|M.leprae_Br4923          ANAGITSDMLIMRMSE--------EQFQKVIDVNLTGVFRVAKLASRNMI
                                      **       :              : .:: :** * *.  :*.:  : 

Mflv_2127|M.gilvum_PYR-GCK          KQEPING----ERGVIINTASVAAFEGQIGQAAYSASKGGVVGMTLPIAR
Mvan_4577|M.vanbaalenii_PYR-1       KQEPING----ERGVIINTASVAAFEGQIGQAAYSASKGGVVGMTLPIAR
MAV_1285|M.avium_104                KTEPIGPGTSPERGVIINTASVAAFEGQIGQAAYSASKGGVVGMTLPIAR
MSMEG_5183|M.smegmatis_MC2_155      KTEPIGP-NGEERGVIINTASVAAFDGQIGQAAYSASKGGVVGMTLPIAR
Mb1176|M.bovis_AF2122/97            KTEPIG----EERGVIINTASVAAFDGQIGQAAYSASKGGVVGMTLPIAR
Rv1144|M.tuberculosis_H37Rv         KTEPIG----EERGVIINTASVAAFDGQIGQAAYSASKGGVVGMTLPIAR
MMAR_4307|M.marinum_M               KTEPVGP-NAEERGVIINTASVAAFDGQIGQAAYSASKGGVVGMTLPIAR
MUL_0987|M.ulcerans_Agy99           KTEPVGP-NAEERGVIINTASVAAFDGQIGQAAYSASKGGVVGMTLPIAR
TH_1570|M.thermoresistible__bu      RNEPSGS-PEDDRGVCILTASVAAWEGQIGQTGYASSKAGIVGMTIVAAR
MAB_0368|M.abscessus_ATCC_1997      QEEPVDE--FGERGAIVNTASVAAFDGQIGQAAYSASKGGIVGMTLPIAR
MLBr_01807|M.leprae_Br4923          KQ---------RFGRYIFMGSVVGLSGVPGQANYAASKSGLIGMARSLAR
                                    :            *  :  .**.. .*  **: *::**.*::**:   **

Mflv_2127|M.gilvum_PYR-GCK          DLSREFIRVCTIAPGLFKTPLLGS--LPEEAQASLGKQVPHPARLGDPDE
Mvan_4577|M.vanbaalenii_PYR-1       DLSRELIRVCTIAPGLFKTPLLGS--LPEEAQASLGKQVPHPARLGDPDE
MAV_1285|M.avium_104                DLARELIRVVTIAPGLFKTPLLGS--LPEEAQASLGKQVPHPARLGDPDE
MSMEG_5183|M.smegmatis_MC2_155      DLSRELIRVVTIAPGLFKTPLLGS--LPEEAQKSLGAQVPHPARLGDPDE
Mb1176|M.bovis_AF2122/97            DLASKLIRVVTIAPGLFDTPLLAS--LPAEAKASLGQQVPHPSRLGNPDE
Rv1144|M.tuberculosis_H37Rv         DLASKLIRVVTIAPGLFDTPLLAS--LPAEAKASLGQQVPHPSRLGNPDE
MMAR_4307|M.marinum_M               DLASHRIRVMTIAPGLFDTPLLAS--LPEEARASLGKQVPHPSRLGSPDE
MUL_0987|M.ulcerans_Agy99           DLASHRIRVMTIAPGLFDTPLLAS--LPEEARASLGKQVPHPSRLGNPDE
TH_1570|M.thermoresistible__bu      DLASKQIRVCTIAPGTFDTPLLAR--VPQPVRENLAASIPHPRRLGDPDE
MAB_0368|M.abscessus_ATCC_1997      DLSVVGIRVNTIAPGLIDTPIYGEGESAQQFKDRLAPNVLYPQRLGNPEE
MLBr_01807|M.leprae_Br4923          ELGSRSITANVVAPGFIDTEMTRA--MDSKYQEAALQAIPLGRIGAVEEI
                                    :*.   * . .:*** :.* :          :      :      .  : 

Mflv_2127|M.gilvum_PYR-GCK          YGALAVHIVENP-MLNGETIRLDGAIRMAPR
Mvan_4577|M.vanbaalenii_PYR-1       YGALAVHIVENP-MLNGETIRLDGAIRMAPR
MAV_1285|M.avium_104                YGALAVHIVENP-MLNGEVIRLDGAIRMAPR
MSMEG_5183|M.smegmatis_MC2_155      YGALAQHIIENP-MLNGEVIRLDGAIRMAPR
Mb1176|M.bovis_AF2122/97            YGALVLHIIENP-MLNGEVIRLDGAIRMAPR
Rv1144|M.tuberculosis_H37Rv         YGALVLHIIENP-MLNGEVIRLDGAIRMAPR
MMAR_4307|M.marinum_M               YGALAVHIIENP-MLNGEVIRLDGAIRMAPR
MUL_0987|M.ulcerans_Agy99           YGALAVHIIENP-MLNGEVIRLDGAIRMAPR
TH_1570|M.thermoresistible__bu      YAQLAMAIIENG-MLNGETIRLDGAIRMAPR
MAB_0368|M.abscessus_ATCC_1997      FASLALELVTNS-YMNAETIRIDGGARLQPK
MLBr_01807|M.leprae_Br4923          AGAVSFLASEDAGYISGAVIPVDGGLGMGH-
                                     . :      :   :.. .* :**.  :

species	id	gene	e-value	identity (len)	annotation
M. thermoresistible (build 8)	TH_1570	-	-	100% (258)	3-Hydroxyacyl-CoA dehydrogenase
M. thermoresistible (build 8)	TH_1987	-	5e-72	56.03% (257)	3-Hydroxyacyl-CoA dehydrogenase
M. thermoresistible (build 8)	TH_3183	-	4e-58	47.67% (258)	PUTATIVE short-chain dehydrogenase/reductase SDR