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MDINGVSAIVTGGASGLGAATARLLAAQGAKVVIADVQDEKGEALAKELGGAFVHTDVTSEADGIAAVDA AKELGPVRVLINCAGVGWPGRTIGKDGQYASAHSLDIFSKVIGINLIGSFNLIRLAATAISQEEPVDEFG ERGAIVNTASVAAFDGQIGQAAYSASKGGIVGMTLPIARDLSVVGIRVNTIAPGLIDTPIYGEGESAQQF KDRLAPNVLYPQRLGNPEEFASLALELVTNSYMNAETIRIDGGARLQPK
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. abscessus ATCC 19977 | MAB_0368 | - | - | 100% (259) | Short-chain dehydrogenase/reductas |
| M. abscessus ATCC 19977 | MAB_4680c | - | 2e-26 | 34.87% (261) | putative short-chain dehydrogenase/reductase |
| M. abscessus ATCC 19977 | MAB_1219 | - | 2e-23 | 32.68% (254) | short chain dehydrogenase |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb1176 | - | 1e-62 | 51.18% (254) | short-chain type dehydrogenase/reductase |
| M. gilvum PYR-GCK | Mflv_3163 | - | 8e-99 | 67.18% (259) | short-chain dehydrogenase/reductase SDR |
| M. tuberculosis H37Rv | Rv1144 | - | 1e-62 | 51.18% (254) | short-chain type dehydrogenase/reductase |
| M. leprae Br4923 | MLBr_01807 | fabG1 | 4e-21 | 31.60% (250) | 3-oxoacyl- |
| M. marinum M | MMAR_4307 | - | 2e-63 | 49.62% (262) | short-chain type dehydrogenase/reductase |
| M. avium 104 | MAV_1285 | - | 5e-66 | 51.33% (263) | 3-hydroxyacyl-CoA dehydrogenase |
| M. smegmatis MC2 155 | MSMEG_0216 | - | 1e-105 | 71.81% (259) | 3-hydroxyacyl-CoA dehydrogenase |
| M. thermoresistible (build 8) | TH_1987 | - | 2e-65 | 53.05% (262) | 3-Hydroxyacyl-CoA dehydrogenase |
| M. ulcerans Agy99 | MUL_0987 | - | 1e-64 | 50.38% (262) | short-chain type dehydrogenase/reductase |
| M. vanbaalenii PYR-1 | Mvan_4577 | - | 2e-68 | 52.87% (261) | short-chain dehydrogenase/reductase SDR |
CLUSTAL 2.0.9 multiple sequence alignment
Mflv_3163|M.gilvum_PYR-GCK -MVRRVPRNGLFYTSAVDVNGTSAIVTGGASGIGAATARLLASQGARVVI
MSMEG_0216|M.smegmatis_MC2_155 ----------MSYAVGVDINGASAIVTGGASGIGAASARLLAAKGAKVVI
MAB_0368|M.abscessus_ATCC_1997 ----------------MDINGVSAIVTGGASGLGAATARLLAAQGAKVVI
MAV_1285|M.avium_104 ----------------MEIKDAVAVVTGGASGLGLATTKRLLDRGAQVVV
Mvan_4577|M.vanbaalenii_PYR-1 ----------------MEIKDAVAVVTGGASGLGLATTKRLLDRGASVVV
TH_1987|M.thermoresistible__bu ----------------VEIKDSVAVVTGGASGLGLATTKRLLDRGAQVVV
Mb1176|M.bovis_AF2122/97 ----------------MKTKDAVAVVTGGASGLGLATTKRLLDAGAQVVV
Rv1144|M.tuberculosis_H37Rv ----------------MKTKDAVAVVTGGASGLGLATTKRLLDAGAQVVV
MMAR_4307|M.marinum_M ----------------MEIRDAVAVVTGGASGLGLATTKRLLDAGAQVVV
MUL_0987|M.ulcerans_Agy99 ----------------MEIRDAVAVVTGGASGLGLATTKRLLDAGAQVVV
MLBr_01807|M.leprae_Br4923 MTDAAAKVSAAPGRGKPAFVSRSILVTGGNRGIGLAVARRLVADGHRVAV
. :**** *:* * :: * * *.:
Mflv_3163|M.gilvum_PYR-GCK ADLQAERGQELAHEIGG--AYVSVDVTDTAQIEDAVNTAIDLG-PLRALV
MSMEG_0216|M.smegmatis_MC2_155 ADLQADKGEALAKELGG--AFVSVDVTETDQIIAAVDKAAELG-PLRALV
MAB_0368|M.abscessus_ATCC_1997 ADVQDEKGEALAKELGG--AFVHTDVTSEADGIAAVDAAKELG-PVRVLI
MAV_1285|M.avium_104 IDLR---GEDAVRELGDRARFVQADVTDEAAVGKALDTAESMG-PLRINV
Mvan_4577|M.vanbaalenii_PYR-1 MDLR---GEEAVKELDARAKFVETNVTDPEQVAAALDAAEEMG-PLRIDV
TH_1987|M.thermoresistible__bu LDLK---GEDAVKALGDRARFVETNVTDEAAVAKALDVAEEMG-PVRINV
Mb1176|M.bovis_AF2122/97 VDLR---GDDVVGGLGDRARFAQADVTDEAAVSNALELADSLG-PVRVVV
Rv1144|M.tuberculosis_H37Rv VDLR---GDDVVGGLGDRARFAQADVTDEAAVSNALELADSLG-PVRVVV
MMAR_4307|M.marinum_M LDIR---GEDVVADLGDRARFAAADVTDEAAVASALDLAETMG-TLRIVV
MUL_0987|M.ulcerans_Agy99 LDIR---GEDVVADLGDRARFAAADVTDEAAVASALDLAETMG-TLRIVV
MLBr_01807|M.leprae_Br4923 THRAS--------VVPDWFFGVECDVTDNDAIGAAFKAVEEHQGPVEVLV
. : . :**. *.. . .:. :
Mflv_3163|M.gilvum_PYR-GCK NSAGIGWAQRTIGKDGEFASAHNLDAYKKVLAINLVGTFDCIRLAATAMS
MSMEG_0216|M.smegmatis_MC2_155 NSAGIGWAQRTIGKDGEYASAHNLDVYKKVLAINLVGTFDCIRIAATAMS
MAB_0368|M.abscessus_ATCC_1997 NCAGVGWPGRTIGKDGQYASAHSLDIFSKVIGINLIGSFNLIRLAATAIS
MAV_1285|M.avium_104 NCAGIGNAIKTLSKDGPFP----LDAFKKVVGVNLIGTFNVLRLAAERIA
Mvan_4577|M.vanbaalenii_PYR-1 NCAGIGNAAKTLSKDGPFP----LDAFKKVVEVNLIGTFNVIRLAAERIA
TH_1987|M.thermoresistible__bu NCAGIGNAIKTLSKNGPFP----LDEFTKVIQVNLIGTFNVLRLAAERIA
Mb1176|M.bovis_AF2122/97 NCAGTGNAIRVLSRDGVFP----LAAFRKIVDINLVGTFNVLRLGAERIA
Rv1144|M.tuberculosis_H37Rv NCAGTGNAIRVLSRDGVFP----LAAFRKIVDINLVGTFNVLRLGAERIA
MMAR_4307|M.marinum_M NCAGTGNAIRVLSRDGVFP----LAAFRKIVDINLVGSFNVLRLAAERIA
MUL_0987|M.ulcerans_Agy99 NCAGTGNAIRVLSRDGVFS----LAAFRKIVDINLVGSFNVLRLAAERIA
MLBr_01807|M.leprae_Br4923 ANAGITSDMLIMRMS--------EEQFQKVIDVNLTGVFRVAKLASRNMI
** : . : *:: :** * * ::.: :
Mflv_3163|M.gilvum_PYR-GCK RLD-LTESG--ERGAIVNMTSVAAFDGQIGQAAYSSSKGGVVGLTLPVAR
MSMEG_0216|M.smegmatis_MC2_155 RNE-PTETG--ERGAIVNMTSVAAFDGQIGQAAYSSSKGGVVGLTLPVAR
MAB_0368|M.abscessus_ATCC_1997 QEEPVDEFG--ERGAIVNTASVAAFDGQIGQAAYSASKGGIVGMTLPIAR
MAV_1285|M.avium_104 KTEPIGPGTSPERGVIINTASVAAFEGQIGQAAYSASKGGVVGMTLPIAR
Mvan_4577|M.vanbaalenii_PYR-1 KQEPING----ERGVIINTASVAAFEGQIGQAAYSASKGGVVGMTLPIAR
TH_1987|M.thermoresistible__bu KTEPLKG---EERGVIINTASVAAFEGQIGQAAYSASKGGVVGMTLPIAR
Mb1176|M.bovis_AF2122/97 KTEPIG----EERGVIINTASVAAFDGQIGQAAYSASKGGVVGMTLPIAR
Rv1144|M.tuberculosis_H37Rv KTEPIG----EERGVIINTASVAAFDGQIGQAAYSASKGGVVGMTLPIAR
MMAR_4307|M.marinum_M KTEPVGP-NAEERGVIINTASVAAFDGQIGQAAYSASKGGVVGMTLPIAR
MUL_0987|M.ulcerans_Agy99 KTEPVGP-NAEERGVIINTASVAAFDGQIGQAAYSASKGGVVGMTLPIAR
MLBr_01807|M.leprae_Br4923 KQR---------FGRYIFMGSVVGLSGVPGQANYAASKSGLIGMARSLAR
: * : **..:.* *** *::**.*::*:: .:**
Mflv_3163|M.gilvum_PYR-GCK DLAAVGIRVNTVAPGLIDTPIYGEGPDSEAFKAKLGESVLYPRRLGKPEE
MSMEG_0216|M.smegmatis_MC2_155 DLSAVGIRVNTVAPGLIDTPIYGEGEGSEAFKAKLGESVLFPHRLGKPEE
MAB_0368|M.abscessus_ATCC_1997 DLSVVGIRVNTIAPGLIDTPIYGEGESAQQFKDRLAPNVLYPQRLGNPEE
MAV_1285|M.avium_104 DLARELIRVVTIAPGLFKTPLLGSLP--EEAQASLGKQVPHPARLGDPDE
Mvan_4577|M.vanbaalenii_PYR-1 DLSRELIRVCTIAPGLFKTPLLGSLP--EEAQASLGKQVPHPARLGDPDE
TH_1987|M.thermoresistible__bu DLARELIRVVTIAPGLFKTPLLGSLP--EEAQKSLGQQVPHPARLGDPDE
Mb1176|M.bovis_AF2122/97 DLASKLIRVVTIAPGLFDTPLLASLP--AEAKASLGQQVPHPSRLGNPDE
Rv1144|M.tuberculosis_H37Rv DLASKLIRVVTIAPGLFDTPLLASLP--AEAKASLGQQVPHPSRLGNPDE
MMAR_4307|M.marinum_M DLASHRIRVMTIAPGLFDTPLLASLP--EEARASLGKQVPHPSRLGSPDE
MUL_0987|M.ulcerans_Agy99 DLASHRIRVMTIAPGLFDTPLLASLP--EEARASLGKQVPHPSRLGNPDE
MLBr_01807|M.leprae_Br4923 ELGSRSITANVVAPGFIDTEMTRAMD---SKYQEAALQAIPLGRIGAVEE
:*. * . .:***::.* : . .. *:* :*
Mflv_3163|M.gilvum_PYR-GCK LASMVVELLTN--SYMNAEVVRVDGGIRMPPK
MSMEG_0216|M.smegmatis_MC2_155 LASMVIELITN--SYMNAEVVRVDGGIRMPPK
MAB_0368|M.abscessus_ATCC_1997 FASLALELVTN--SYMNAETIRIDGGARLQPK
MAV_1285|M.avium_104 YGALAVHIVEN--PMLNGEVIRLDGAIRMAPR
Mvan_4577|M.vanbaalenii_PYR-1 YGALAVHIVEN--PMLNGETIRLDGAIRMAPR
TH_1987|M.thermoresistible__bu YGALAVHIVEN--PMLNGEVIRLDGAIRMAPR
Mb1176|M.bovis_AF2122/97 YGALVLHIIEN--PMLNGEVIRLDGAIRMAPR
Rv1144|M.tuberculosis_H37Rv YGALVLHIIEN--PMLNGEVIRLDGAIRMAPR
MMAR_4307|M.marinum_M YGALAVHIIEN--PMLNGEVIRLDGAIRMAPR
MUL_0987|M.ulcerans_Agy99 YGALAVHIIEN--PMLNGEVIRLDGAIRMAPR
MLBr_01807|M.leprae_Br4923 IAGAVSFLASEDAGYISGAVIPVDGGLGMGH-
.. . : : :.. .: :**. :