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aa seq not available
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. thermoresistible (build 8) | TH_3281 | - | - | 100% (498) | feruloyl-CoA synthetase |
| M. thermoresistible (build 8) | TH_3448 | - | 2e-68 | 36.47% (510) | PUTATIVE putative AMP-dependent synthetase and ligase |
| M. thermoresistible (build 8) | TH_2854 | - | 1e-64 | 35.15% (515) | PUTATIVE putative AMP-dependent synthetase and ligase |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb0276 | fadD2 | 1e-54 | 32.34% (504) | acyl-CoA synthetase |
| M. gilvum PYR-GCK | Mflv_2385 | - | 6e-71 | 35.32% (504) | AMP-dependent synthetase and ligase |
| M. tuberculosis H37Rv | Rv0270 | fadD2 | 1e-54 | 32.34% (504) | acyl-CoA synthetase |
| M. leprae Br4923 | MLBr_02546 | fadD2 | 3e-53 | 31.52% (495) | acyl-CoA synthetase |
| M. abscessus ATCC 19977 | MAB_4559 | - | 2e-70 | 35.98% (503) | putative long-chain-fatty-acid CoA ligase |
| M. marinum M | MMAR_0466 | - | 3e-59 | 33.00% (494) | long-chain-fatty-acid-CoA ligase |
| M. avium 104 | MAV_1867 | - | 9e-68 | 36.69% (507) | AMP-dependent synthetase and ligase |
| M. smegmatis MC2 155 | MSMEG_3694 | - | 1e-176 | 63.64% (506) | feruloyl-CoA synthetase |
| M. ulcerans Agy99 | MUL_1115 | - | 1e-58 | 32.79% (494) | long-chain-fatty-acid-CoA ligase |
| M. vanbaalenii PYR-1 | Mvan_4263 | - | 8e-66 | 34.72% (504) | AMP-dependent synthetase and ligase |
CLUSTAL 2.0.9 multiple sequence alignment
TH_3281|M.thermoresistible__bu --------------------------------------------------
MSMEG_3694|M.smegmatis_MC2_155 --------------------------------------------------
MAB_4559|M.abscessus_ATCC_1997 --------------------------------------------------
MAV_1867|M.avium_104 --------------------------------------------------
Mflv_2385|M.gilvum_PYR-GCK --------------------------------------------------
Mvan_4263|M.vanbaalenii_PYR-1 --------------------------------------------------
MMAR_0466|M.marinum_M --------------------------------------------------
MUL_1115|M.ulcerans_Agy99 --------------------------------------------------
Mb0276|M.bovis_AF2122/97 MPNLTDLPGQAVSKLQKSIGQYVARGTAELHYLRKIIESGAIGLEPPLNY
Rv0270|M.tuberculosis_H37Rv MPNLTDLPGQAVSKLQKSIGQYVARGTAELHYLRKIIESGAIGLEPPLNY
MLBr_02546|M.leprae_Br4923 -----------MTKLR----HYLERGAAEVHYLRSIFESGALGFEPPLTY
TH_3281|M.thermoresistible__bu ---------MTLIHDLIEHAAHATPDRPAVATPGGTVITFAEFDRLVRNV
MSMEG_3694|M.smegmatis_MC2_155 ---------MSLLHQLISSVAAAAPHRPAIIADDGSTIGYAEFDHQIRAV
MAB_4559|M.abscessus_ATCC_1997 ----------MQFTQWLHRALQQYPDRLITIDQGREHTVEQFADRVARLS
MAV_1867|M.avium_104 ---MCADDLDLTLGDIVTDNAVRFGDVPAYKLGSRMVTHAQLHDRAVQLV
Mflv_2385|M.gilvum_PYR-GCK ----------MSISLLLEMATDAGPDRTAVVSDDTRLTTAELSALADGGA
Mvan_4263|M.vanbaalenii_PYR-1 ----------MSISLLLEMAQDAGPDRTAVVSDDLRLTTAELSALADGGA
MMAR_0466|M.marinum_M ----------MSVSLLLEMAASASPDRIAVVSGDLRLTTQQLSDLADGGA
MUL_1115|M.ulcerans_Agy99 ----------MSVSLLLEMAASASPDRIAVVSGDLRLKTQQLSDLADGGA
Mb0276|M.bovis_AF2122/97 AALAADIRKWGEVGMLPSHNARRAPNRAAVIDEEGTLTFSELDEAAHAVA
Rv0270|M.tuberculosis_H37Rv AALAADIRKWGEVGMLPSHNARRAPNRAAVIDEEGTLTFSELDEAAHAVA
MLBr_02546|M.leprae_Br4923 AAMAVAMRKWGDLAMLPAMPARRSPHRAALIDEEGTLTYKELDRAAHALA
. .
TH_3281|M.thermoresistible__bu ASWLAAHSRRGDRIAVVADNSPAYAVLYYAVPRSGRVLALINQRLHPDEQ
MSMEG_3694|M.smegmatis_MC2_155 ARWIASRTEPGDRVAVIADNSPAYAVLYYAVPLGGRVLTLINQRLSPAEQ
MAB_4559|M.abscessus_ATCC_1997 AGLRANGVRPGDRVGMLSLNSDRYIEYLTAVPWLGAALNAVNIRWSLAEI
MAV_1867|M.avium_104 SAMAAAGVRRQDRVAVLSRNSVEFGEVMAATHLSGVIMATVNFRLSPDEV
Mflv_2385|M.gilvum_PYR-GCK GVIAASGAR---HVAYVGTGGALLPLLLFASARAAVPVTPLNYRLSAEGL
Mvan_4263|M.vanbaalenii_PYR-1 GVIAASGAR---HVAYVGAGGAMLPLLLFASARAAVPVTPLNYRLSADGL
MMAR_0466|M.marinum_M GAIAASDAQ---HVVYVGTGGAMLPLLIFASARAGLPFTSINYRLSADGI
MUL_1115|M.ulcerans_Agy99 GAIAASDAQ---HVVYVGTGGAMLPLLIFASARAGLPFTSINYRLSADGI
Mb0276|M.bovis_AF2122/97 NGLLAKGVRAGDGVAILARNHRWFVIANYGAARVGARIILLNSEFSGPQI
Rv0270|M.tuberculosis_H37Rv NGLLAKGVRAGDGVAILARNHRWFVIANYGAARVGARIILLNSEFSGPQI
MLBr_02546|M.leprae_Br4923 NGLIAKGVRGGDGIAILARNHRWFVIANYGCARVGARIILLNSEFSGPQI
* . : :. . . . . :* .
TH_3281|M.thermoresistible__bu VAQLVRTGATVLFGDPEHLAALSNSAALHGQLDHVVGFGGAGWRQVLA--
MSMEG_3694|M.smegmatis_MC2_155 AAQLETTRPALVLGDTVYLDALP-------QIDSVA-FGSPAWRDAVS--
MAB_4559|M.abscessus_ATCC_1997 GYSLRESGTRVLLVDDTFKAAAAPLRAACACLETVIYCGAGPAPQDMIGY
MAV_1867|M.avium_104 LDVLKRVSPSMVFCSDEFALVAAGLAPQLASPPLLVSIGG-SGRTGMLDF
Mflv_2385|M.gilvum_PYR-GCK RALLDRLPDPLVVVDDEYRDAVGDSYRTMGSREFFEASRTAEPAAEFA--
Mvan_4263|M.vanbaalenii_PYR-1 RALLDRLPDPLVVVDDEYRDAVGDGYRTIGSAEFLDAARTAEPAAEFA--
MMAR_0466|M.marinum_M AALIRRLPRPLVVVDERYRDTIAAD-QSLSSQQFLELAGRAEPVAEFP--
MUL_1115|M.ulcerans_Agy99 AALIRRLPRPLVVVDERYRETIAAD-QSLSSQQFLELAGRAEPVAEFP--
Mb0276|M.bovis_AF2122/97 KEVSDREGAKVIIYDDEYTKAVSLAQPPLGKLRALGVNPDDDKPSGSSDE
Rv0270|M.tuberculosis_H37Rv KEVSDREGAKVIIYDDEYTKAVSLAQPPLGKLRALGVNPDDDKPSGSSDE
MLBr_02546|M.leprae_Br4923 KEVSEREGAKVIIYDDEYTKVVSKAEPALGKLRALGVNPDEEEPPGSTDE
::. . . . .
TH_3281|M.thermoresistible__bu ---TTSGP--VD--PPGPDDPAWLLFTSGSTGTPKPVLHTHRSVLAGVWG
MSMEG_3694|M.smegmatis_MC2_155 ---TTAAAPEVDHAEAQPGDPAWLLFTSGSTGVPKGVVHSHRSILAAVHG
MAB_4559|M.abscessus_ATCC_1997 EDLLASHEPIDDTRTGG-DSLLGVFYTGGTTGNPKGVMLSHNNVLASAMG
MAV_1867|M.avium_104 EEFVGGGDGGRLPFAARPDDIACLLFTSGTTGASKCCILGQAELRRVAF-
Mflv_2385|M.gilvum_PYR-GCK ----------------DPDSVGVVLFTSGTTSKPKAVELTHTNLTSYIMG
Mvan_4263|M.vanbaalenii_PYR-1 ----------------DPDAVGVVLFTSGTTSKPKAVELSHANLTSYIMG
MMAR_0466|M.marinum_M ----------------DPDSVAIVLFTSGTTSQPKAVELTHSNLTSYVTT
MUL_1115|M.ulcerans_Agy99 ----------------DPDSVAIVLFTSGTTSQPKAVELTHSNLTSYVTT
Mb0276|M.bovis_AF2122/97 TLAELIAHSSTAPAPKASRRASIIILTSGTTGTPKGANRNTPPTLAPIGG
Rv0270|M.tuberculosis_H37Rv TLAELIAHSSTAPAPKASRRASIIILTSGTTGTPKGANRNTPPTLAPIGG
MLBr_02546|M.leprae_Br4923 TLAELIARSSSAPAPKVRKRASIIILTSGTTGTPKGANRNTPASLAPLGG
:: *.*:*. .*
TH_3281|M.thermoresistible__bu TVAGRSVQP-SAVYLLPFPMCHIAGYNMLVH-HAVGATVVLVDRFRPETS
MSMEG_3694|M.smegmatis_MC2_155 TVDGRSVTP-AGVYLLPFPMCHIAGYNMLVQ-HAVGATVVLMSRFRPESF
MAB_4559|M.abscessus_ATCC_1997 SLSTGNFLTRGGRLLHSAPMFHMADFSAVLAGNLSGSTHVIVPSFSPQGV
MAV_1867|M.avium_104 TMNVEMRTGSSDRGLINMPMFHVGAMAIVAGLHARGGSVVLQQQFDAGEA
Mflv_2385|M.gilvum_PYR-GCK TVEFASAEP-DDAALICVPPYHIAGVSAALSNLYAGRKMVYLRHFDAEKW
Mvan_4263|M.vanbaalenii_PYR-1 TVEFASAEP-DDAALICVPPYHIAGVSAALSNLYAGRKMVYLTQFDAGRW
MMAR_0466|M.marinum_M TVEFGCAAP-SDAALICVPPYHIAGVSAVLSNLYAGRKMVYLTNFDAHEW
MUL_1115|M.ulcerans_Agy99 TVEFGCAAP-SDAALICVPPYHIAGVSAVLSNLYAGRKMVYLNNFDAHEW
Mb0276|M.bovis_AF2122/97 ILSHVPFKA-GEVTLLPSPMFHALGYMHAALAMFLGSTLVLRRRFKPALV
Rv0270|M.tuberculosis_H37Rv ILSHVPFKA-GEVTLLPSPMFHALGYMHAALAMFLGSTLVLRRRFKPALV
MLBr_02546|M.leprae_Br4923 ILSKVPFRA-HEVTLLPAPMFHALGYLHATLAMFLGSTLVLRRRFKPATV
: * * * * . * * .
TH_3281|M.thermoresistible__bu AQAVIEYGVTSCSLAPTMLHSLLAHLTATGA--RLPTLSAVAYGSAAMPA
MSMEG_3694|M.smegmatis_MC2_155 AAQVRAHGVRSCSLAPTMLHALLAHVESTGT--TLPTLEAVAYGSAAMPL
MAB_4559|M.abscessus_ATCC_1997 LDAIVAHDVQDMLLVPTMIQMLVDHPGAAQL--DLSGIRSITYGASVISE
MAV_1867|M.avium_104 VQLITDERITLLHLAPVMLRALLDEITDPR---GLDCLRTVIYSAAPMTV
Mflv_2385|M.gilvum_PYR-GCK VRLVADEGVTSATVVPTMLDRIVTVLETTDT--ALPTLRTLAYGGSKVPL
Mvan_4263|M.vanbaalenii_PYR-1 VDLVTGEGVTSATVVPTMLDRIVSVLETRGT--TLPTLRTLAYGGSKVPL
MMAR_0466|M.marinum_M VRLTNAEQVTTATVVPTMLDRIVAVLETGEH--KLPSLRNLAYGGSKVGL
MUL_1115|M.ulcerans_Agy99 VRLTNAEQVTTATVVPTMLDRIVAVLETGEH--KLPSLRNLAYGCSKVGL
Mb0276|M.bovis_AF2122/97 LEDIEKHKATSMVVVPVMLSRILDQLEKTEPKPDLSSLKIVFVSGSQLGA
Rv0270|M.tuberculosis_H37Rv LEDIEKHKATSMVVVPVMLSRILDQLEKTEPKPDLSSLKIVFVSGSQLGA
MLBr_02546|M.leprae_Br4923 LEDIEKHQATAMVVVPVMLSRILDTLENLETKSDLSSLRVVFVSGSQLGA
:.*.*: :: * : : . : :
TH_3281|M.thermoresistible__bu GLIRRAIELLD-VDFHQGYGMTETAGNVTFLGPDDHRS-------DDPEI
MSMEG_3694|M.smegmatis_MC2_155 DLLRRAIEALG-VEFHQGYGMTETGGNVTFLGPDDHRAGAA----GHPEV
MAB_4559|M.abscessus_ATCC_1997 AVLQRATRVFPNARFTQAYGMTEVSPVATLLLPDDHDDP---------AL
MAV_1867|M.avium_104 HTLRRALSVLPRTGFLNLYGQTEAIVSGLPRELHDADSPD------AADA
Mflv_2385|M.gilvum_PYR-GCK PLVRKALSLLPDVGFVNAYGLTETSSTIAVLTPDDHRAALAAADDAALRR
Mvan_4263|M.vanbaalenii_PYR-1 PLVRKALSLLPAVGFVNAYGLTETSSTIAVLTPDDHRAALAASDEAAIRR
MMAR_0466|M.marinum_M PLVRRALELLPDVGFVNAYGLTETSSTIAVLTPDDHRAAQSAAAAGLARR
MUL_1115|M.ulcerans_Agy99 PLVRRALELLPDVGFVNAYRLTETSSTIAVLTPDDHRAAQSAAAAGLARR
Mb0276|M.bovis_AF2122/97 ELATRALGDLGPVIYN-MYGSTEVAFATIAGPKDLQFNP-----------
Rv0270|M.tuberculosis_H37Rv ELATRALGDLGPVIYN-MYGSTEVAFATIAGPKDLQFNP-----------
MLBr_02546|M.leprae_Br4923 ELATRALEELGPVIYN-MYGSTEIAFATIAGPKDLQINS-----------
:* : . : * ** .
TH_3281|M.thermoresistible__bu LASAGRPHDGVRLRIVDPHGVEVAPGGIGEIQVRGEQVCS----------
MSMEG_3694|M.smegmatis_MC2_155 LVSAGHPHSGVEIGIVDADGAPLPPGGIGEIVVRGAQVARGYWPDR----
MAB_4559|M.abscessus_ATCC_1997 LRSAGRAAPHCEVRIVDPDDNEVPRGEIGEVIVKGDNVMLGYWELPEESA
MAV_1867|M.avium_104 LRSVGFPFPGVRVRIVGDDGRDVLPGEAGEIVVRSDSRFRGYWDDPVATL
Mflv_2385|M.gilvum_PYR-GCK LGSVGQPVPGIEVEVRAEDGTVLGPGETGELFVRGEQVSGKYTDIG---S
Mvan_4263|M.vanbaalenii_PYR-1 LGSVGQPVPGIEVEIRADDGTVLGAGETGELFVRGEQVSGKYTDIG---S
MMAR_0466|M.marinum_M LGSVGRPVPGVELQIRGQDGRVLGPGETGELFVRGGQVSGRYTGIG---S
MUL_1115|M.ulcerans_Agy99 LGSVGRPVPGVELQIRGQDGRVLGPGETGELFVRGEQVSGRYTGIG---S
Mb0276|M.bovis_AF2122/97 -STVGPVVKGVTVKILDENGNEVPQGAVGRIFVGNAFPFEGYTGGG---G
Rv0270|M.tuberculosis_H37Rv -STVGPVVKGVTVKILDENGNEVPQGAVGRIFVGNAFPFEGYTGGG---G
MLBr_02546|M.leprae_Br4923 -ATVGPVVKGVKVKILDDSGKEVPRGQVGRIFVGNAFPFEGYTGGG---G
:.* : : . : * *.: * .
TH_3281|M.thermoresistible__bu ----PGWLATGDVGRLDRTGRLTVVDRAKDIIITGGENVSSREVEDVLSS
MSMEG_3694|M.smegmatis_MC2_155 PSTVDGWLHTGDIGRLDHTGRLFVVDRLKDIIVTGGENVSSREVEDVLSG
MAB_4559|M.abscessus_ATCC_1997 AAIRDGWMHTGDAGRMDDRGYVYIVDRIKDMVVTGGENVYSAEVENALAK
MAV_1867|M.avium_104 ATLRDGWCHTGDVGRFDHRGLLYLVDRKKDVIITGGENVYSPEVEEVLGG
Mflv_2385|M.gilvum_PYR-GCK VLDENGWFPTKDVAYLDSEGYLFIGGRSDDTIIRGGENIAPAEIEDVLVE
Mvan_4263|M.vanbaalenii_PYR-1 VLDEQGWFPTKDVAFLDEEGYLFIGGRSDDTIIRGGENIAPAEIEDVLVE
MMAR_0466|M.marinum_M VLDGHGWFGTKDIAMLDEDGYLFIGGRSDDTIIRGGENIAPAELEEVLIE
MUL_1115|M.ulcerans_Agy99 VLDGHGWFGTKDIAMLDEDGYLFIGGRSDDTIIRGGENIAPAELEEVLIE
Mb0276|M.bovis_AF2122/97 KQIIDGLLSSGDVGYFDERGLLYVSGRDDEMIVSGGENVFPAEVEDLISG
Rv0270|M.tuberculosis_H37Rv KQIIDGLLSSGDVGYFDERGLLYVSGRDDEMIVSGGENVFPAEVEDLISG
MLBr_02546|M.leprae_Br4923 KQIIDGLLSSGDVGYFDEHDLLYISGRDDEMIVSGGENVFPAEVEDLISG
* : * . :* . : : .* .: :: ****: . *:*: :
TH_3281|M.thermoresistible__bu HPGVDMCAVVAAPDEHWGEAVCAVVVPRRRPPPTADDLVAHVRSRLAAFK
MSMEG_3694|M.smegmatis_MC2_155 HPDVDMVAVVGVPDGYWGEAVCAVVVPVPGRNPRADDLIDHVRSAIAAFK
MAB_4559|M.abscessus_ATCC_1997 HPAVAACAVIGIPDEQWGERVHAVVVKQAQSECCDGDLQEHCREHIANYK
MAV_1867|M.avium_104 CEGVAACAVVGAPDEKWGEAVCAVVVPTPGATPTLEAVQEFVRSSLAGYK
Mflv_2385|M.gilvum_PYR-GCK HPHVRDCAVVGADDPQWGQIIVAVVVPHQDTAPDPEDLRAHVRSQLRGSR
Mvan_4263|M.vanbaalenii_PYR-1 HPHVRDCAVVGADDPEWGQIIVAVVVAQPGTEPDVEDLRSHVRSQLRGSR
MMAR_0466|M.marinum_M HPQVRDVAVVGVEDAQWGQEIVAVVVPVAGVDPDPEELREFVRRSLRGSR
MUL_1115|M.ulcerans_Agy99 HPQVRDVAVVGVEDAQWGQEIVAVVVPVAGVDPDPEELREFVRRSLRGSR
Mb0276|M.bovis_AF2122/97 HPDVVEAAAIGVDDKEFGARLRAFVVKKPGADLDEDTIKQYVRDHLARYK
Rv0270|M.tuberculosis_H37Rv HPDVVEAAAIGVDDKEFGARLRAFVVKKPGADLDEDTIKQYVRDHLARYK
MLBr_02546|M.leprae_Br4923 HPEVVEATAIGVDDKEWGARLRAFVVKKQDATIDEDAIKAYVRDHLARYK
* :.:. * :* : *.** : . * : :
TH_3281|M.thermoresistible__bu RPRHVLFVDELPMTPNGKVAKDEVRRHVRERLTPHTLENRT
MSMEG_3694|M.smegmatis_MC2_155 RPREVLFVDELPLTGNGKIAKDRVRDIARTALTA-------
MAB_4559|M.abscessus_ATCC_1997 VPRSFEFVDELPLSGAGKILKRVLRQKYWESRDAGVS----
MAV_1867|M.avium_104 VPRRLVVVSDLPVLASGKVDKKRLRAEIAAAAAD-------
Mflv_2385|M.gilvum_PYR-GCK TPDRVVFRDELPTNATGKVLRRELVSELNQDRSPAQPAV--
Mvan_4263|M.vanbaalenii_PYR-1 TPDRVVFRDELPTNATGKVLRRELVDELNQDPSPAQPAV--
MMAR_0466|M.marinum_M TPDRVVFRHELPTTATGKILRREIIEELAGTKS--------
MUL_1115|M.ulcerans_Agy99 TPDRVVFRRELPTTATGKILRREIIEELAGTKS--------
Mb0276|M.bovis_AF2122/97 VPREVIFLDELPRNPTGKVLKRELRKL--------------
Rv0270|M.tuberculosis_H37Rv VPREVIFLDELPRNPTGKVLKRELRKL--------------
MLBr_02546|M.leprae_Br4923 VPREVIFLEELPRNPTGKVLKRELRDFEVH-----------
* . . :** **: : :