For questions or suggestions e-mail us at: ioerger@cs.tamu.edu

M. thermoresistible (build 8) TH_3180 (-)

annotation: acyl-CoA dehydrogenase domain protein
coordinates: 483137 - 484288
length: 384

aa seq not available

Operon Prediction Model: Genebank

Paralogs
speciesidgenee-valueidentity (len)annotation
M. thermoresistible (build 8)TH_3180--100% (384)acyl-CoA dehydrogenase domain protein
M. thermoresistible (build 8)TH_2583-1e-9648.53% (375) PUTATIVE peptidase S1 and S6, chymotrypsin/Hap
M. thermoresistible (build 8)TH_4527-5e-9445.07% (375) PUTATIVE acyl-CoA dehydrogenase domain protein

Closest Orthologs (e-value cutoff: 1e-4)
speciesidgenee-valueidentity (len)annotation
M. bovis AF2122 / 97Mb2743cfadE201e-10249.35% (385) acyl-CoA dehydrogenase FADE20
M. gilvum PYR-GCKMflv_4601-1e-12557.82% (377) acyl-CoA dehydrogenase domain-containing protein
M. tuberculosis H37RvRv2724cfadE201e-10149.09% (385) acyl-CoA dehydrogenase FADE20
M. leprae Br4923MLBr_00737fadE258e-5133.59% (384) putative acyl-CoA dehydrogenase
M. abscessus ATCC 19977MAB_2081-1e-12455.82% (378) acyl CoA dehydrogenase
M. marinum MMMAR_3132-1e-12555.50% (382) acyl-CoA dehydrogenase
M. avium 104MAV_2703-1e-10349.47% (376) putative acyl-CoA dehydrogenase
M. smegmatis MC2 155MSMEG_5197-2e-9545.60% (375) long-chain specific acyl-CoA dehydrogenase
M. ulcerans Agy99MUL_3367fadE201e-10250.94% (371) acyl-CoA dehydrogenase FadE20
M. vanbaalenii PYR-1Mvan_2439-1e-10249.33% (375) long-chain-acyl-CoA dehydrogenase

CLUSTAL 2.0.9 multiple sequence alignment


Mb2743c|M.bovis_AF2122/97           MGS-----ATKYQRTLFEPEHELFRESYRAFLDRHVAAYHDEWEKTKIVD
Rv2724c|M.tuberculosis_H37Rv        MGS-----ATKYQRTLFEPEHELFRESYRAFLDRHVAPYHDEWEKTKIVD
MUL_3367|M.ulcerans_Agy99           MGS-----AIKYQRTLFEPEHDLFRESYRGFLERHVALYHDEWEKAKIVD
Mvan_2439|M.vanbaalenii_PYR-1       MGASEAKPVIAYERTLFEPEHDMFRESFRAFLDRHVAPHHEEWEKNKLVD
MSMEG_5197|M.smegmatis_MC2_155      -----------MKRLIYNEEHEAFRQTVKEYIERELVPHSEKWEAERIVD
MAB_2081|M.abscessus_ATCC_1997      --------MSSPISPWMNAELLELRDLAAKFFSAELAPHANRFADQHHVD
MMAR_3132|M.marinum_M               --------MTASISPWMSAELLELRDLAAKFFSTELAPHAQRFADQHQVD
Mflv_4601|M.gilvum_PYR-GCK          --------MAANRSSWMDDDLDALRDLARTFCEKEVAPHSARFIEQHHVD
TH_3180|M.thermoresistible__bu      -------MITKRMSPWFDDEVRALYDLAREFFEREVVAHVDTWDAQRHID
MAV_2703|M.avium_104                ----MSELFPDYRPSWETDQHRELRKHAAEFFRKEATPNQERWAAQHAVD
MLBr_00737|M.leprae_Br4923          --MVGWSGNPLFDLFKLPEEHNELRATIRALAEKEIAPHAADVDQRARFP
                                                       :   :          . .           . 

Mb2743c|M.bovis_AF2122/97           RGVWLEAGKQGFLGMAVPEEYGGGGNADFRYNTVITEETCAGRYSGIGFG
Rv2724c|M.tuberculosis_H37Rv        RGVWLEAGKQGFLGMAVPEEYGGGGNADFRYNTVITEETCAGRYSGIGFG
MUL_3367|M.ulcerans_Agy99           RGVWLEAGKQGFLGMAVPEEYGGGGNPDFRYNTIITEETSAGRYSGIGFG
Mvan_2439|M.vanbaalenii_PYR-1       RDVWLEAGKQGFLGMAVPEEYGGGGVDDFRYNTIVTEEVTAGRYTGLGFS
MSMEG_5197|M.smegmatis_MC2_155      RSAYTAAGKYGLIGFNMPEEFGGGGSDDFRFNAIIDEEIAKSGVHGPALS
MAB_2081|M.abscessus_ATCC_1997      RELWNRAGELGLLCMSIPEEYGGGG-GTFAHEAVVLEEQARIGDSSWGAG
MMAR_3132|M.marinum_M               RELWHKAGELGLLCMSIPEEYGGGG-GTFAHEAVVLEEQARVGDSSWGAG
Mflv_4601|M.gilvum_PYR-GCK          RDLWTRAGDLGLLCMSIPEQYGGGG-GTFAHEAVLIEEQARIGDSAWGAP
TH_3180|M.thermoresistible__bu      RQVWLEAGKLGLLLCSVPEEYGGGG-GTFAHDVAVFDAQGYSGDLSLGIA
MAV_2703|M.avium_104                REFWNKAGDAGLLGLDLPEEYGGAG-GDFAMNVVVQEELAYAYDQGFGFA
MLBr_00737|M.leprae_Br4923          EEALAALNASGFNAIHVPEEYGGQG-ADSVAACIVIEEVARVDASASLIP
                                    .      .  *:    :**::** *         : :        .    

Mb2743c|M.bovis_AF2122/97           LHNDIVAPYLLALATEEQKRRWFPNFCTGELTTAIAMTEPGTGSDLQGIT
Rv2724c|M.tuberculosis_H37Rv        LHNDIVAPYLLALATEEQKRRWFPNFCTGELITAIAMTEPGTGSDLQGIT
MUL_3367|M.ulcerans_Agy99           LHNEIVAPYLLALATEEQKQRRLPKFCTGEFITAIAMTEPGTGSDLQGIK
Mvan_2439|M.vanbaalenii_PYR-1       LHNDVAAPYLIRLATEEQKQRWLPKFCSGEIISAIAMTEPGTGSDLQGIK
MSMEG_5197|M.smegmatis_MC2_155      LHNDVVGPYFKELANDEQRRRWLPGITSGELIIAIAMTEPGAGSDLAGIR
MAB_2081|M.abscessus_ATCC_1997      LHSGIVAHYILQYATEELRAQWLPKMASGEMIGAIAMTEPGTGSDLQSVK
MMAR_3132|M.marinum_M               LHSGIVAHYILQYAAEELRRQWLPKMASGEMIGAIAMTEPGTGSDLQSVK
Mflv_4601|M.gilvum_PYR-GCK          LHSGIVAHYLLEYGTDEQKERFLPRLATGEMVGAIAMTEPGTGSDLQSVT
TH_3180|M.thermoresistible__bu      VHSGIVPHYIVKYGSEEQKRQWLPPMATGEVLSAIGMTEPGAGSDLKAIR
MAV_2703|M.avium_104                VHSPIVAHYIWAYGSDEQRRRWLPKIISGEAVLAIAMTEPGTGSDLQSVK
MLBr_00737|M.leprae_Br4923          AVNKLGTMGLILRGSEELKKQVLPSLAAEGAMASYALSEREAGSDAASMR
                                      . :    :   . :* : : :* : :     : .::*  :***  .: 

Mb2743c|M.bovis_AF2122/97           TRAVKHGDHYVLNGSKTFITNGINSDLVIVVAQTDPEKGAQGFSLLVVER
Rv2724c|M.tuberculosis_H37Rv        TRAVKHGDHYVLNGSKTFITNGINSDLVIVVAQTDPEKGAQGFSLLVVER
MUL_3367|M.ulcerans_Agy99           TRAVKQGDHYLLNGSKTFITNGINADLVIVVAQTDPEKGAQGFSLLVVER
Mvan_2439|M.vanbaalenii_PYR-1       TRAVRDGDHYVLNGAKTFITNGIHSDLVIVVAQTDPDKGALGFSLLVVER
MSMEG_5197|M.smegmatis_MC2_155      TSAVRDGDDWIINGSKTFISSGINCDLCVVVARTDPEAGHKGFSLFVVER
MAB_2081|M.abscessus_ATCC_1997      TKALLDGDEYVITGSKTFITNGQQADLIIVVAKTDPSQGAAGISLIVVEA
MMAR_3132|M.marinum_M               TKAILDGDEYVITGAKTFITNGQQADLIIVVAKTDPSQGAAGISLIVAEA
Mflv_4601|M.gilvum_PYR-GCK          TKASRVGDEYVVNGSKTFITNGAQADLIIVVAKTDPSAGANGISLVLVEG
TH_3180|M.thermoresistible__bu      TTAVRDGDEYIVNGSKTFITNGGSADMILLAVKTDPKAGARGISLLIVDL
MAV_2703|M.avium_104                TTARRDGDFYVINGSKTFISNGTHCDLLVIVAKTDPSKGAAGVSLIVAET
MLBr_00737|M.leprae_Br4923          TRAKADGDDWILNGFKCWITNGGKSTWYTVMAVTDPDKGANGISAFIVHK
                                    * *   ** :::.* * :*:.*  .    : . ***. *  *.* .:.. 

Mb2743c|M.bovis_AF2122/97           --GMAGFERGRQLDKIGLDAQDTAELSFTDVAVPAENLLGQ-EGMGFIYL
Rv2724c|M.tuberculosis_H37Rv        --GMAGFERGRQLDKIGLDAQDTAELSFTDVAVPAENLLGQ-EGMGFIYL
MUL_3367|M.ulcerans_Agy99           --GMEGFERGRHLDKIGLDAQDTAELSFSDVQVPVENLLGQ-EGMGFIYL
Mvan_2439|M.vanbaalenii_PYR-1       --GMAGFERGRKLDKIGLDAQDTAELSFTDVKVPVENLLGE-EGQGFIYL
MSMEG_5197|M.smegmatis_MC2_155      --GMEGFTRGRKLDKMGLHSQDTSELHFENVRVPHANLLGK-EGRGFYHL
MAB_2081|M.abscessus_ATCC_1997      --DRAGFRRGKVLDKIGQRGQDTSELFFDEVRVPRSHLLGQAEGQGFIQL
MMAR_3132|M.marinum_M               --DRPGFRRGKVLDKIGQRGQDTSELFFDDVRVPRSHLLGETEGQGFIQL
Mflv_4601|M.gilvum_PYR-GCK          --DRPGFRRGRVLDKVGQRGQDTSELYFEDVHIPVENLLGTTEGQGFIQL
TH_3180|M.thermoresistible__bu      R-DCDGYQVTRVLDKVGQHGADTAELSFTDVRVPVANLLGAEEGKGFGQM
MAV_2703|M.avium_104                DENLAGFERGRVLAKMGQHAQDTRELFFSDMRVPVANLLGAQEGLGFYQL
MLBr_00737|M.leprae_Br4923          --DDEGFSIGPKEKKLGIKGSPTTELYFDKCRIPGDRIIGE-PGTGFKTA
                                      .  *:       *:*  .  * ** * .  :*  .::*   * **   

Mb2743c|M.bovis_AF2122/97           MQNLPQERISIAIMAAAGMESVLEQTLQYAKERKAFGRSIGSFQNSRFLL
Rv2724c|M.tuberculosis_H37Rv        MQNLPQERISIAIMAAAGMESVLEQTLQYAKERKAFGRSIGSFQNSRFLL
MUL_3367|M.ulcerans_Agy99           MQNLPQERISIAIMAAAGMESVLDQTLQYTKERKAFGRSIGNFQNSRFVL
Mvan_2439|M.vanbaalenii_PYR-1       MQNLPQERISIAIMAAAAMEAVLDVTLQYTKERKAFGRPIGSQQNSRFLL
MSMEG_5197|M.smegmatis_MC2_155      MTNLPSERLSIAISAIAGARAVFDETLQYCKDRKAFGQPIGSFQHNRFLL
MAB_2081|M.abscessus_ATCC_1997      MTQLPQERLIVAVGAVAAMELALEQTLKYTREREAFGRPVFGFQNTKFTL
MMAR_3132|M.marinum_M               MTQLPQERLIVAVGAVAAMELAVEQTLKYTREREAFGRPVFGFQNTKFIL
Mflv_4601|M.gilvum_PYR-GCK          MQQLPQERLILALGAVTVLETALEFTVEYTKDRHAFGKPVFAFQNTKFKL
TH_3180|M.thermoresistible__bu      IDQLAQERLAVAAQAMGGMERAVDDTVAYTKSREAFGQSIFDFQNTAFEL
MAV_2703|M.avium_104                MEQLARERLIIATICAALAEVAVLEAIKYSREREAFGRPIGKFQHTKFVL
MLBr_00737|M.leprae_Br4923          LATLDHTRPTIGAQAVGIAQGALDAAIVYTKDRKQFGESISTFQSIQFML
                                    :  *   *  :.  .    . ..  :: * :.*. **..:   *   * *

Mb2743c|M.bovis_AF2122/97           AELATEATVVRIMVDEFIKLHLAGKLTA-EQAAMAKWYATEKQVYLNDRC
Rv2724c|M.tuberculosis_H37Rv        AELATEATVVRIMVDEFIKLHLAGKLTA-EQAAMAKWYATEKQVYLNDRC
MUL_3367|M.ulcerans_Agy99           AELATEATMVRIMVDESIELHLDGKLTA-EQAAMAKWYSTEKQVSLNDRC
Mvan_2439|M.vanbaalenii_PYR-1       AELSTEATVVRMMVDEFIKLHLQDKLTV-EQAAMAKWYSTEKQVHLIDRC
MSMEG_5197|M.smegmatis_MC2_155      AEMETELEVTENYIDRCLQGVVDGELTA-VEAAKAKWWATETAKKIVDNC
MAB_2081|M.abscessus_ATCC_1997      AEAATETRIARVFLDYCIDLHLAGQLDV-QTVAMAKWWTTERAMKVLDDC
MMAR_3132|M.marinum_M               AEAATETRIARVFLDYCIDLHLAGQLDV-QTVAMAKWWTTERAMKVLDDC
Mflv_4601|M.gilvum_PYR-GCK          AEVATDAHISRVFIDDCVARHLRGELDI-PTVAMAKWWTTERAMVALDDC
TH_3180|M.thermoresistible__bu      AECATIARTCRAFFDQCVEAHLRGELDG-TDAAMAKYWLTDRQCEVVDRC
MAV_2703|M.avium_104                AECKTEALAIKTMVDYAVGQYLDGKNDP-ATASMAKLFAAEKSDQIVDKC
MLBr_00737|M.leprae_Br4923          ADMAMKVEAARLIVYAAAARAERGEPDLGFISAASKCFASDIAMEVTTDA
                                    *:        .  .         .:       : :* : ::        .

Mb2743c|M.bovis_AF2122/97           LQLHGGYGYMREYPVARAYLDSRVQTIYGGTTEIMKEIIGRGLGV
Rv2724c|M.tuberculosis_H37Rv        LQLHGGYGYMREYPVARAYLDSRVQTIYGGTTEIMKEIIGRGLGV
MUL_3367|M.ulcerans_Agy99           LQLHGGYGYMREYPVARAYLDSRVQTIYGGTTEIMKEIIGRSLGI
Mvan_2439|M.vanbaalenii_PYR-1       LQLHGGYGYMREYDVARAYLDARVQTIYGGTTEIMKEIIGRSLGV
MSMEG_5197|M.smegmatis_MC2_155      VQLHGGYGYMMEYRVARAYVDGRIQTIFGGTTEIMKEIIGRDLGV
MAB_2081|M.abscessus_ATCC_1997      MQLHGGYGYMTEYPISRLWVDQRVQKIYAGTNEVMKEIISRSL--
MMAR_3132|M.marinum_M               LQLHGGYGYMTEYPISRLWVDQRVQKIYAGTNEVMKEIISRSL--
Mflv_4601|M.gilvum_PYR-GCK          LQLHGGYGYMTEYPIGRMWADARVQKIYGGTNEIMKEIIARSL--
TH_3180|M.thermoresistible__bu      VQLHGGYGYMREYLIARMYEDARVQRIYAGANEVMKQIIARSL--
MAV_2703|M.avium_104                LQIFGGYGYMTEYPIANMYTASRVNRKYGRTSEIMKEIISRSL--
MLBr_00737|M.leprae_Br4923          VQLFGGAGYTSDFPVERFMRDAKITQIYEGTNQIQRVVMSRALLR
                                    :*:.** **  :: : .     ::   :  :.:: : ::.* *