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M. avium 104 MAV_2703 (-)

annotation: putative acyl-CoA dehydrogenase
coordinates: 2736204 - 2737367
length: 387

SELFPDYRPSWETDQHRELRKHAAEFFRKEATPNQERWAAQHAVDREFWNKAGDAGLLGLDLPEEYGGAG
GDFAMNVVVQEELAYAYDQGFGFAVHSPIVAHYIWAYGSDEQRRRWLPKIISGEAVLAIAMTEPGTGSDL
QSVKTTARRDGDFYVINGSKTFISNGTHCDLLVIVAKTDPSKGAAGVSLIVAETDENLAGFERGRVLAKM
GQHAQDTRELFFSDMRVPVANLLGAQEGLGFYQLMEQLARERLIIATICAALAEVAVLEAIKYSREREAF
GRPIGKFQHTKFVLAECKTEALAIKTMVDYAVGQYLDGKNDPATASMAKLFAAEKSDQIVDKCLQIFGGY
GYMTEYPIANMYTASRVNRKYGRTSEIMKEIISRSL*

Operon Prediction Model: Genebank

Paralogs

species id gene e-value identity (len) annotation
M. avium 104 MAV_2703 - - 100% (387) putative acyl-CoA dehydrogenase
M. avium 104 MAV_3616 - e-103 49.61% (381) long-chain specific acyl-CoA dehydrogenase
M. avium 104 MAV_2600 - 1e-92 45.84% (373) acyl-CoA dehydrogenase

Closest Orthologs (e-value cutoff: 1e-4)

species id gene e-value identity (len) annotation
M. bovis AF2122 / 97 Mb2743c fadE20 1e-100 50.13% (373) acyl-CoA dehydrogenase FADE20
M. gilvum PYR-GCK Mflv_4601 - 1e-111 53.03% (379) acyl-CoA dehydrogenase domain-containing protein
M. tuberculosis H37Rv Rv2724c fadE20 1e-101 50.40% (373) acyl-CoA dehydrogenase FADE20
M. leprae Br4923 MLBr_00737 fadE25 5e-45 29.14% (374) putative acyl-CoA dehydrogenase
M. abscessus ATCC 19977 MAB_1863 - 1e-172 76.49% (387) acyl-CoA dehydrogenase FadE
M. marinum M MMAR_3132 - 1e-119 56.91% (376) acyl-CoA dehydrogenase
M. smegmatis MC2 155 MSMEG_5197 - 3e-98 48.13% (374) long-chain specific acyl-CoA dehydrogenase
M. thermoresistible (build 8) TH_3180 - 1e-103 49.47% (376) PUTATIVE acyl-CoA dehydrogenase domain protein
M. ulcerans Agy99 MUL_3367 fadE20 1e-101 50.67% (373) acyl-CoA dehydrogenase FadE20
M. vanbaalenii PYR-1 Mvan_2439 - 1e-103 50.40% (373) long-chain-acyl-CoA dehydrogenase

CLUSTAL 2.0.9 multiple sequence alignment


Mb2743c|M.bovis_AF2122/97           MGS-----ATKYQRTLFEPEHELFRESYRAFLDRHVAAYHDEWEKTKIVD
Rv2724c|M.tuberculosis_H37Rv        MGS-----ATKYQRTLFEPEHELFRESYRAFLDRHVAPYHDEWEKTKIVD
MUL_3367|M.ulcerans_Agy99           MGS-----AIKYQRTLFEPEHDLFRESYRGFLERHVALYHDEWEKAKIVD
Mvan_2439|M.vanbaalenii_PYR-1       MGASEAKPVIAYERTLFEPEHDMFRESFRAFLDRHVAPHHEEWEKNKLVD
MSMEG_5197|M.smegmatis_MC2_155      -----------MKRLIYNEEHEAFRQTVKEYIERELVPHSEKWEAERIVD
MAV_2703|M.avium_104                ----MSELFPDYRPSWETDQHRELRKHAAEFFRKEATPNQERWAAQHAVD
MAB_1863|M.abscessus_ATCC_1997      ----MSELFPAYRASWETDAHRDLRKHAAEFLRKESTPNQERWSAQHQVD
Mflv_4601|M.gilvum_PYR-GCK          --------MAANRSSWMDDDLDALRDLARTFCEKEVAPHSARFIEQHHVD
MMAR_3132|M.marinum_M               --------MTASISPWMSAELLELRDLAAKFFSTELAPHAQRFADQHQVD
TH_3180|M.thermoresistible__bu      -------MITKRMSPWFDDEVRALYDLAREFFEREVVAHVDTWDAQRHID
MLBr_00737|M.leprae_Br4923          --MVGWSGNPLFDLFKLPEEHNELRATIRALAEKEIAPHAADVDQRARFP
                                                           :          . .           . 

Mb2743c|M.bovis_AF2122/97           RGVWLEAGKQGFLGMAVPEEYGGGGNADFRYNTVITEETCAGRYSGIGFG
Rv2724c|M.tuberculosis_H37Rv        RGVWLEAGKQGFLGMAVPEEYGGGGNADFRYNTVITEETCAGRYSGIGFG
MUL_3367|M.ulcerans_Agy99           RGVWLEAGKQGFLGMAVPEEYGGGGNPDFRYNTIITEETSAGRYSGIGFG
Mvan_2439|M.vanbaalenii_PYR-1       RDVWLEAGKQGFLGMAVPEEYGGGGVDDFRYNTIVTEEVTAGRYTGLGFS
MSMEG_5197|M.smegmatis_MC2_155      RSAYTAAGKYGLIGFNMPEEFGGGGSDDFRFNAIIDEEIAKSGVHGPALS
MAV_2703|M.avium_104                REFWNKAGDAGLLGLDLPEEYGGAG-GDFAMNVVVQEELAYAYDQGFGFA
MAB_1863|M.abscessus_ATCC_1997      REFWNKMGDAGLLGLDLPEEYGGAG-GDFGFSAVVGEELALAQDTSTGWA
Mflv_4601|M.gilvum_PYR-GCK          RDLWTRAGDLGLLCMSIPEQYGGGG-GTFAHEAVLIEEQARIGDSAWGAP
MMAR_3132|M.marinum_M               RELWHKAGELGLLCMSIPEEYGGGG-GTFAHEAVVLEEQARVGDSSWGAG
TH_3180|M.thermoresistible__bu      RQVWLEAGKLGLLLCSVPEEYGGGG-GTFAHDVAVFDAQGYSGDLSLGIA
MLBr_00737|M.leprae_Br4923          EEALAALNASGFNAIHVPEEYGGQG-ADSVAACIVIEEVARVDASASLIP
                                    .      .  *:    :**::** *         : :        .    

Mb2743c|M.bovis_AF2122/97           LHNDIVAPYLLALATEEQKRRWFPNFCTGELTTAIAMTEPGTGSDLQGIT
Rv2724c|M.tuberculosis_H37Rv        LHNDIVAPYLLALATEEQKRRWFPNFCTGELITAIAMTEPGTGSDLQGIT
MUL_3367|M.ulcerans_Agy99           LHNEIVAPYLLALATEEQKQRRLPKFCTGEFITAIAMTEPGTGSDLQGIK
Mvan_2439|M.vanbaalenii_PYR-1       LHNDVAAPYLIRLATEEQKQRWLPKFCSGEIISAIAMTEPGTGSDLQGIK
MSMEG_5197|M.smegmatis_MC2_155      LHNDVVGPYFKELANDEQRRRWLPGITSGELIIAIAMTEPGAGSDLAGIR
MAV_2703|M.avium_104                VHSPIVAHYIWAYGSDEQRRRWLPKIISGEAVLAIAMTEPGTGSDLQSVK
MAB_1863|M.abscessus_ATCC_1997      VHSPIVAHYINTYGNEEQRARWMPGIISGDLVLAIAMTEPGTGSDLQAVR
Mflv_4601|M.gilvum_PYR-GCK          LHSGIVAHYLLEYGTDEQKERFLPRLATGEMVGAIAMTEPGTGSDLQSVT
MMAR_3132|M.marinum_M               LHSGIVAHYILQYAAEELRRQWLPKMASGEMIGAIAMTEPGTGSDLQSVK
TH_3180|M.thermoresistible__bu      VHSGIVPHYIVKYGSEEQKRQWLPPMATGEVLSAIGMTEPGAGSDLKAIR
MLBr_00737|M.leprae_Br4923          AVNKLGTMGLILRGSEELKKQVLPSLAAEGAMASYALSEREAGSDAASMR
                                      . :    :   . :* : : :* : :     : .::*  :***  .: 

Mb2743c|M.bovis_AF2122/97           TRAVKHGDHYVLNGSKTFITNGINSDLVIVVAQTDPEKGAQGFSLLVVER
Rv2724c|M.tuberculosis_H37Rv        TRAVKHGDHYVLNGSKTFITNGINSDLVIVVAQTDPEKGAQGFSLLVVER
MUL_3367|M.ulcerans_Agy99           TRAVKQGDHYLLNGSKTFITNGINADLVIVVAQTDPEKGAQGFSLLVVER
Mvan_2439|M.vanbaalenii_PYR-1       TRAVRDGDHYVLNGAKTFITNGIHSDLVIVVAQTDPDKGALGFSLLVVER
MSMEG_5197|M.smegmatis_MC2_155      TSAVRDGDDWIINGSKTFISSGINCDLCVVVARTDPEAGHKGFSLFVVER
MAV_2703|M.avium_104                TTARRDGDFYVINGSKTFISNGTHCDLLVIVAKTDPSKGAAGVSLIVAET
MAB_1863|M.abscessus_ATCC_1997      TTAIPDGDHYVINGSKTFISNGTHCDLLVIVAKTDPSQGAAGVSLIVAET
Mflv_4601|M.gilvum_PYR-GCK          TKASRVGDEYVVNGSKTFITNGAQADLIIVVAKTDPSAGANGISLVLVEG
MMAR_3132|M.marinum_M               TKAILDGDEYVITGAKTFITNGQQADLIIVVAKTDPSQGAAGISLIVAEA
TH_3180|M.thermoresistible__bu      TTAVRDGDEYIVNGSKTFITNGGSADMILLAVKTDPKAGARGISLLIVDL
MLBr_00737|M.leprae_Br4923          TRAKADGDDWILNGFKCWITNGGKSTWYTVMAVTDPDKGANGISAFIVHK
                                    * *   ** :::.* * :*:.*  .    : . ***. *  *.* .:.. 

Mb2743c|M.bovis_AF2122/97           --GMAGFERGRQLDKIGLDAQDTAELSFTDVAVPAENLLG-QEGMGFIYL
Rv2724c|M.tuberculosis_H37Rv        --GMAGFERGRQLDKIGLDAQDTAELSFTDVAVPAENLLG-QEGMGFIYL
MUL_3367|M.ulcerans_Agy99           --GMEGFERGRHLDKIGLDAQDTAELSFSDVQVPVENLLG-QEGMGFIYL
Mvan_2439|M.vanbaalenii_PYR-1       --GMAGFERGRKLDKIGLDAQDTAELSFTDVKVPVENLLG-EEGQGFIYL
MSMEG_5197|M.smegmatis_MC2_155      --GMEGFTRGRKLDKMGLHSQDTSELHFENVRVPHANLLG-KEGRGFYHL
MAV_2703|M.avium_104                DENLAGFERGRVLAKMGQHAQDTRELFFSDMRVPVANLLGAQEGLGFYQL
MAB_1863|M.abscessus_ATCC_1997      KD-LPGFERGRVLEKVGQHGQDTRELFFTDMRVPIANRLGDKDGLGFYQL
Mflv_4601|M.gilvum_PYR-GCK          -D-RPGFRRGRVLDKVGQRGQDTSELYFEDVHIPVENLLGTTEGQGFIQL
MMAR_3132|M.marinum_M               -D-RPGFRRGKVLDKIGQRGQDTSELFFDDVRVPRSHLLGETEGQGFIQL
TH_3180|M.thermoresistible__bu      RD-CDGYQVTRVLDKVGQHGADTAELSFTDVRVPVANLLGAEEGKGFGQM
MLBr_00737|M.leprae_Br4923          --DDEGFSIGPKEKKLGIKGSPTTELYFDKCRIPGDRIIG-EPGTGFKTA
                                         *:       *:*  .  * ** * .  :*  . :*   * **   

Mb2743c|M.bovis_AF2122/97           MQNLPQERISIAIMAAAGMESVLEQTLQYAKERKAFGRSIGSFQNSRFLL
Rv2724c|M.tuberculosis_H37Rv        MQNLPQERISIAIMAAAGMESVLEQTLQYAKERKAFGRSIGSFQNSRFLL
MUL_3367|M.ulcerans_Agy99           MQNLPQERISIAIMAAAGMESVLDQTLQYTKERKAFGRSIGNFQNSRFVL
Mvan_2439|M.vanbaalenii_PYR-1       MQNLPQERISIAIMAAAAMEAVLDVTLQYTKERKAFGRPIGSQQNSRFLL
MSMEG_5197|M.smegmatis_MC2_155      MTNLPSERLSIAISAIAGARAVFDETLQYCKDRKAFGQPIGSFQHNRFLL
MAV_2703|M.avium_104                MEQLARERLIIATICAALAEVAVLEAIKYSREREAFGRPIGKFQHTKFVL
MAB_1863|M.abscessus_ATCC_1997      MEQLARERLIIAAVCSGMAEGALIEAIKYTKEREAFGKPLIKFQNTKFQL
Mflv_4601|M.gilvum_PYR-GCK          MQQLPQERLILALGAVTVLETALEFTVEYTKDRHAFGKPVFAFQNTKFKL
MMAR_3132|M.marinum_M               MTQLPQERLIVAVGAVAAMELAVEQTLKYTREREAFGRPVFGFQNTKFIL
TH_3180|M.thermoresistible__bu      IDQLAQERLAVAAQAMGGMERAVDDTVAYTKSREAFGQSIFDFQNTAFEL
MLBr_00737|M.leprae_Br4923          LATLDHTRPTIGAQAVGIAQGALDAAIVYTKDRKQFGESISTFQSIQFML
                                    :  *   *  :.  .    . ..  :: * :.*. **..:   *   * *

Mb2743c|M.bovis_AF2122/97           AELATEATVVRIMVDEFIKLHLAGKLTA-EQAAMAKWYATEKQVYLNDRC
Rv2724c|M.tuberculosis_H37Rv        AELATEATVVRIMVDEFIKLHLAGKLTA-EQAAMAKWYATEKQVYLNDRC
MUL_3367|M.ulcerans_Agy99           AELATEATMVRIMVDESIELHLDGKLTA-EQAAMAKWYSTEKQVSLNDRC
Mvan_2439|M.vanbaalenii_PYR-1       AELSTEATVVRMMVDEFIKLHLQDKLTV-EQAAMAKWYSTEKQVHLIDRC
MSMEG_5197|M.smegmatis_MC2_155      AEMETELEVTENYIDRCLQGVVDGELTA-VEAAKAKWWATETAKKIVDNC
MAV_2703|M.avium_104                AECKTEALAIKTMVDYAVGQYLDGKNDP-ATASMAKLFAAEKSDQIVDKC
MAB_1863|M.abscessus_ATCC_1997      AELKAEVLSIKTTVDYCVQDYINGNNDP-ATASMAKLIAADKAVSVVDRC
Mflv_4601|M.gilvum_PYR-GCK          AEVATDAHISRVFIDDCVARHLRGELDI-PTVAMAKWWTTERAMVALDDC
MMAR_3132|M.marinum_M               AEAATETRIARVFLDYCIDLHLAGQLDV-QTVAMAKWWTTERAMKVLDDC
TH_3180|M.thermoresistible__bu      AECATIARTCRAFFDQCVEAHLRGELDG-TDAAMAKYWLTDRQCEVVDRC
MLBr_00737|M.leprae_Br4923          ADMAMKVEAARLIVYAAAARAERGEPDLGFISAASKCFASDIAMEVTTDA
                                    *:        .  .         .:       : :*   ::        .

Mb2743c|M.bovis_AF2122/97           LQLHGGYGYMREYPVARAYLDSRVQTIYGGTTEIMKEIIGRGLGV
Rv2724c|M.tuberculosis_H37Rv        LQLHGGYGYMREYPVARAYLDSRVQTIYGGTTEIMKEIIGRGLGV
MUL_3367|M.ulcerans_Agy99           LQLHGGYGYMREYPVARAYLDSRVQTIYGGTTEIMKEIIGRSLGI
Mvan_2439|M.vanbaalenii_PYR-1       LQLHGGYGYMREYDVARAYLDARVQTIYGGTTEIMKEIIGRSLGV
MSMEG_5197|M.smegmatis_MC2_155      VQLHGGYGYMMEYRVARAYVDGRIQTIFGGTTEIMKEIIGRDLGV
MAV_2703|M.avium_104                LQIFGGYGYMTEYPIANMYTASRVNRKYGRTSEIMKEIISRSL--
MAB_1863|M.abscessus_ATCC_1997      VQFFGGYGYMMEYPIARAYAAARVNKIYGGTSEIMKEIISRSL--
Mflv_4601|M.gilvum_PYR-GCK          LQLHGGYGYMTEYPIGRMWADARVQKIYGGTNEIMKEIIARSL--
MMAR_3132|M.marinum_M               LQLHGGYGYMTEYPISRLWVDQRVQKIYAGTNEVMKEIISRSL--
TH_3180|M.thermoresistible__bu      VQLHGGYGYMREYLIARMYEDARVQRIYAGANEVMKQIIARSL--
MLBr_00737|M.leprae_Br4923          VQLFGGAGYTSDFPVERFMRDAKITQIYEGTNQIQRVVMSRALLR
                                    :*:.** **  :: : .     ::   :  :.:: : ::.* *

species	id	gene	e-value	identity (len)	annotation
M. avium 104	MAV_2703	-	-	100% (387)	putative acyl-CoA dehydrogenase
M. avium 104	MAV_3616	-	e-103	49.61% (381)	long-chain specific acyl-CoA dehydrogenase
M. avium 104	MAV_2600	-	1e-92	45.84% (373)	acyl-CoA dehydrogenase