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M. thermoresistible (build 8) TH_3163 (-)

annotation: putative Integrase, catalytic region
coordinates: 4186827 - 4188032
length: 402

aa seq not available

Operon Prediction Model: Genebank

Paralogs
speciesidgenee-valueidentity (len)annotation
M. thermoresistible (build 8)TH_3163--100% (402)putative Integrase, catalytic region
M. thermoresistible (build 8)TH_2026-1e-0631.33% (166) transposase

Closest Orthologs (e-value cutoff: 1e-4)
speciesidgenee-valueidentity (len)annotation
M. bovis AF2122 / 97Mb2836-1e-0628.79% (132) transposase
M. gilvum PYR-GCK-----
M. tuberculosis H37RvRv2812-2e-1627.87% (305) transposase
M. leprae Br4923-----
M. abscessus ATCC 19977-----
M. marinum MMMAR_1373-9e-3330.50% (400) transposase for ISMyma05
M. avium 104MAV_3347-2e-0925.30% (328) transposase
M. smegmatis MC2 155MSMEG_6600-3e-0726.01% (323) transposase
M. ulcerans Agy99-----
M. vanbaalenii PYR-1Mvan_0573-3e-3135.08% (305) integrase catalytic subunit

CLUSTAL 2.0.9 multiple sequence alignment


MMAR_1373|M.marinum_M               -----------------MLQELRMS------EMRYRAVLEVLDG-APVTA
Mvan_0573|M.vanbaalenii_PYR-1       -----------------MTQQLPNSPNDWVIEHRYRAVRQVLDG-VSKSQ
MAV_3347|M.avium_104                MKCELLKNAQLTPEVFVSHRNAPLS-----ETGRLRLARCVVEDGWSLRR
MSMEG_6600|M.smegmatis_MC2_155      ----------------MVHRNAPLS-----ETGRLRLARCVVDDGWSRRR
Mb2836|M.bovis_AF2122/97            --------------------------------------------------
Rv2812|M.tuberculosis_H37Rv         ----MAVGDDEEKVRAERARAIGLFRYQLIWEAADAAHSTKQRGKMVREL
TH_3163|M.thermoresistible__bu      -----------------MAQKVTAMD--------IRMAAAVAGEIDNVAE
                                                                                      

MMAR_1373|M.marinum_M               VARRFGVSRQTVHAWLRRYAEEGAALNLEDRSSRPHRCPHQMPVEVEARV
Mvan_0573|M.vanbaalenii_PYR-1       VAQECGASRQSVHSWVIRYEALGVAG-LADRSRRPLTSPNELSPAVVAMV
MAV_3347|M.avium_104                AAERFQVAVTTAQRWASRYRELGPAG-MADRSSRPLRSPNQTPTRTERRI
MSMEG_6600|M.smegmatis_MC2_155      AAERFQVSVTTVCRWVNRYLELGEAG-MADRSSRPHHSPNRTPTRTERRI
Mb2836|M.bovis_AF2122/97            --------------------------------------------------
Rv2812|M.tuberculosis_H37Rv         ASREHTDPFGRRVRISRQTIDRWIRGWRAGGFDALVPNPRQCTPRTPAEV
TH_3163|M.thermoresistible__bu      FCRRRKISRQTFYKFRRRFRDSGIEG-LQELSRRPLTSPGQTPVEVEDLI
                                                                                      

MMAR_1373|M.marinum_M               LTLR----DAHPRWGPTRIVYELQR--DGVPVVPGRSS-VYRALVRNGRI
Mvan_0573|M.vanbaalenii_PYR-1       CELR----RTYPRWGAQRIAHELAL--RGVDAPPSRSS-VYRILVRHGLV
MAV_3347|M.avium_104                IKVR----VLR-RWGPARIAYLLGLNVSTVHRVLTRYK-LAKLRWLDRAT
MSMEG_6600|M.smegmatis_MC2_155      IGVR----VTR-RWGPARIAYLLRLNVSTVHNVLRRYR-IARLRWLDRAT
Mb2836|M.bovis_AF2122/97            --------------------------------------------------
Rv2812|M.tuberculosis_H37Rv         LELA----VALRRENPQRTAAAIRRILRTQLGWAPDER-TLQRNFHRLGL
TH_3163|M.thermoresistible__bu      VLRRKQLIEQGRDHGAQSIVWSFERDGVTVPSVSTVWQRGWQILSRRGAI
                                                                                      

MMAR_1373|M.marinum_M               DPAKRRRRRSDYKRWERGRPMELWQMDVVGGLHLRDGIEVKVVTGIDDNS
Mvan_0573|M.vanbaalenii_PYR-1       AAQQQNHKR-KYRRWQRDAPMQLWQIDIMGGVFLVDGRECKVVTGIDDHS
MAV_3347|M.avium_104                GQVVRRMEAACCGDLVHVDVKKLGKIPAGGGWRMLGRTVGNRNAQADKTS
MSMEG_6600|M.smegmatis_MC2_155      GRVVRRMESAACGDLVHADVKKLGKIPAGGGWRMLGRTAGRKNSLADKSS
Mb2836|M.bovis_AF2122/97            --------------------------------------------------
Rv2812|M.tuberculosis_H37Rv         TGATTGSAPAVFGRFEAEHPNALWTGDVLHGIRIDLRKTYLFAFLDDHSR
TH_3163|M.thermoresistible__bu      TPQPQKRPKSATKRFVFSCPNECWQSDWTG-WVLADGSPAGIAGSLDDHS
                                                                                      

MMAR_1373|M.marinum_M               RFVVSAKVVAR-ATARPVCAALLEALRRHGVPEQILTDNGKVFTGRFGPG
Mvan_0573|M.vanbaalenii_PYR-1       RFVVMATVVAD-PGARAVCAAFTATMAIYGVPSEVLTDNGKQFTGRFTKP
MAV_3347|M.avium_104                GERSKHRHPLRGYHFLHTAIDAHSRLAYSELLTDERKETAAAFWLRAQAW
MSMEG_6600|M.smegmatis_MC2_155      GVKTRNGDPARGYHFLHSALDAHSRLVYSEMLADERKDTASEFWKRANSW
Mb2836|M.bovis_AF2122/97            ---------------MRLAAALRPALASRGVPNAVYVDNGSPYVD-----
Rv2812|M.tuberculosis_H37Rv         --LVPGYRWGHAEDTVRLAAALRPALASRGVPNAVYVDNGSPYVD-----
TH_3163|M.thermoresistible__bu      RYVPALRACAGDADAQLVWETMLAGIAECGIPSMSLTDNGIVYTGRFHAH
                                                             :    :      :..  :       

MMAR_1373|M.marinum_M               GSSAEVLFDRVCVENG---------------IGHLLTAPRSPTTTGKVER
Mvan_0573|M.vanbaalenii_PYR-1       -YPAEVLFERICRENG---------------ITTRLTKPRSPTTTGKIER
MAV_3347|M.avium_104                FTTCGFTVRKVLTDNGSCYRSHAFRDALG-DIEHRRTRPYRPQTNGKVER
MSMEG_6600|M.smegmatis_MC2_155      FFEQGVIVRTVLTDNGSCYRSHSFREALGDDIEHRRTRPYRPQTNGKVER
Mb2836|M.bovis_AF2122/97            -----AWLLRACAKLG---------------VRLVHSTPGRPQGRGKIER
Rv2812|M.tuberculosis_H37Rv         -----AWLLRACAKLG---------------VRLVHSTPGRPQGRGKIER
TH_3163|M.thermoresistible__bu      ----QSAFETNLRALG---------------VQTINATPFHPQTCGKIER
                                           .       *               :    : *  *   **:**

MMAR_1373|M.marinum_M               LHKTMRAEIFAEVDG--------VFDAIAELQAAIDRWVQYYNTARPHQS
Mvan_0573|M.vanbaalenii_PYR-1       FHKTLRRELLDSAG---------PFASIEVAQEAIDAWVHGYNHSRPHQS
MAV_3347|M.avium_104                FHRTLADEWAYARL----------YRSDAERCAEFPRWLHTYNHHRGHTA
MSMEG_6600|M.smegmatis_MC2_155      FHRTLADEWAYARL----------YTSDEQRCQEYPRWLHTYNHHRGHTA
Mb2836|M.bovis_AF2122/97            FFRTVREQFLVEITGEPDVVGRHYVADLAELNRLFTAWVETVYHRSVHSE
Rv2812|M.tuberculosis_H37Rv         FFRTVREQFLVEITGEPDVVGRHYVADLAELNRLFTAWVETVYHRSVHSE
TH_3163|M.thermoresistible__bu      FWQTLKKWLTARDP----------ATTIAELNALLEQFRTFYNHQRPHRA
                                    : :*:                                :         *  

MMAR_1373|M.marinum_M               LGMVAPAARFALAAGPDLSVVEPVAAVPAEGQHPGALVDLRDAGVRRWVN
Mvan_0573|M.vanbaalenii_PYR-1       LGMATPATMFRPAP---IEVVPPVP-VDTEPLTPDVVVPPRPRRHLPPAT
MAV_3347|M.avium_104                LGGQPPATRVPNLSGQYI--------------------------------
MSMEG_6600|M.smegmatis_MC2_155      LGGQPPASRVPNLSGQYT--------------------------------
Mb2836|M.bovis_AF2122/97            TG-QTPLARWSAGG-------------PIPLPAPETLTEAFLWEEHRRVT
Rv2812|M.tuberculosis_H37Rv         TG-QTPLARWSAGG-------------PIPLPAPETLTEAFLWEEHRRVT
TH_3163|M.thermoresistible__bu      HRGALPAEVFAAGD--------------KARPADRPVPAPVIVSRHTVGP
                                         *                                            

MMAR_1373|M.marinum_M               RHGSISVAG-------------------FRYRVPIVLAGEPVSVVVADNL
Mvan_0573|M.vanbaalenii_PYR-1       EHALIEVVHAVEWEAVLTPRARLLLPGDQQFKFTAALARREVTVWASDRS
MAV_3347|M.avium_104                --------------------------------------------------
MSMEG_6600|M.smegmatis_MC2_155      --------------------------------------------------
Mb2836|M.bovis_AF2122/97            KTATVSLHG-------------------NRYEIDPALVGRKVELVFDPFD
Rv2812|M.tuberculosis_H37Rv         KTATVSLHG-------------------NRYEIDPALVGRKVELVFDPFD
TH_3163|M.thermoresistible__bu      TSGYVFVAP-------------------YKVNVGLRWAGHECDIIRDGQH
                                                                                      

MMAR_1373|M.marinum_M               VSIYHHDVLVASHVQHRKTDN--TTGVVRQGRRTARPVTS-GIVVTRVVD
Mvan_0573|M.vanbaalenii_PYR-1       IHIVLDGTVIRTRPSRLSEHD--LRDLLRRGARIAGPEPARGAATIDILT
MAV_3347|M.avium_104                --------------------------------------------------
MSMEG_6600|M.smegmatis_MC2_155      --------------------------------------------------
Mb2836|M.bovis_AF2122/97            LTRIEVRLAGAPMGRAIPYHIGRHSHPKAKPETPTAPPKPSGIDYAQLIE
Rv2812|M.tuberculosis_H37Rv         LTRIEVRLAGAPMRRAIPYHIGRHSHPKAKPETPTAPPKPSGIDYAQLIE
TH_3163|M.thermoresistible__bu      ITILSGTTLVRSFTADPTRNYQRGDKTTRTYRTREPKPPS----------
                                                                                      

MMAR_1373|M.marinum_M               SNGDVSFAGTMYRAGRVWRGKQ---VEVSIVAESVQIACAGAIVRTHAIR
Mvan_0573|M.vanbaalenii_PYR-1       TSAVIEVARTVSRDGCIGLGGDKVLLESTLVGQRVTLRFEGALMHVVANG
MAV_3347|M.avium_104                --------------------------------------------------
MSMEG_6600|M.smegmatis_MC2_155      --------------------------------------------------
Mb2836|M.bovis_AF2122/97            TAHAAELARGVNYTALTGAADQIPGQLDLLTGQEAQPK------------
Rv2812|M.tuberculosis_H37Rv         TAHAAELARGVNYTALTGAADQIPGQLDLLTGQEAQPK------------
TH_3163|M.thermoresistible__bu      --------------------------------------------------
                                                                                      

MMAR_1373|M.marinum_M               ------------HDRAKEHGAFAT-----PHGRPRKPRQDAPEGPGVKAT
Mvan_0573|M.vanbaalenii_PYR-1       RLVKTMPAPLPPDQRATLRGARPTSEPLPPPAPPNRAMRRVAANGTITIA
MAV_3347|M.avium_104                --------------------------------------------------
MSMEG_6600|M.smegmatis_MC2_155      --------------------------------------------------
Mb2836|M.bovis_AF2122/97            --------------------------------------------------
Rv2812|M.tuberculosis_H37Rv         --------------------------------------------------
TH_3163|M.thermoresistible__bu      --------------------------------------------------
                                                                                      

MMAR_1373|M.marinum_M               PLRGRP----EGRALTPAP-------------------------------
Mvan_0573|M.vanbaalenii_PYR-1       GQRLRVGRSYQGRTVAVAIDDTVFRVFIDGTEICTHARRTDTDITIFKAY
MAV_3347|M.avium_104                --------------------------------------------------
MSMEG_6600|M.smegmatis_MC2_155      --------------------------------------------------
Mb2836|M.bovis_AF2122/97            --------------------------------------------------
Rv2812|M.tuberculosis_H37Rv         --------------------------------------------------
TH_3163|M.thermoresistible__bu      --------------------------------------------------
                                                                                      

MMAR_1373|M.marinum_M               ------
Mvan_0573|M.vanbaalenii_PYR-1       PRRHGT
MAV_3347|M.avium_104                ------
MSMEG_6600|M.smegmatis_MC2_155      ------
Mb2836|M.bovis_AF2122/97            ------
Rv2812|M.tuberculosis_H37Rv         ------
TH_3163|M.thermoresistible__bu      ------