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M. vanbaalenii PYR-1 Mvan_0573 (-)

annotation: integrase catalytic subunit
coordinates: 613853 - 615646
length: 597

VTQQLPNSPNDWVIEHRYRAVRQVLDGVSKSQVAQECGASRQSVHSWVIRYEALGVAGLADRSRRPLTSP
NELSPAVVAMVCELRRTYPRWGAQRIAHELALRGVDAPPSRSSVYRILVRHGLVAAQQQNHKRKYRRWQR
DAPMQLWQIDIMGGVFLVDGRECKVVTGIDDHSRFVVMATVVADPGARAVCAAFTATMAIYGVPSEVLTD
NGKQFTGRFTKPYPAEVLFERICRENGITTRLTKPRSPTTTGKIERFHKTLRRELLDSAGPFASIEVAQE
AIDAWVHGYNHSRPHQSLGMATPATMFRPAPIEVVPPVPVDTEPLTPDVVVPPRPRRHLPPATEHALIEV
VHAVEWEAVLTPRARLLLPGDQQFKFTAALARREVTVWASDRSIHIVLDGTVIRTRPSRLSEHDLRDLLR
RGARIAGPEPARGAATIDILTTSAVIEVARTVSRDGCIGLGGDKVLLESTLVGQRVTLRFEGALMHVVAN
GRLVKTMPAPLPPDQRATLRGARPTSEPLPPPAPPNRAMRRVAANGTITIAGQRLRVGRSYQGRTVAVAI
DDTVFRVFIDGTEICTHARRTDTDITIFKAYPRRHGT
Operon Prediction Model: Genebank

Paralogs
speciesidgenee-valueidentity (len)annotation
M. vanbaalenii PYR-1Mvan_0573--100% (597)integrase catalytic subunit
M. vanbaalenii PYR-1Mvan_0458-e-10862.18% (312) integrase catalytic subunit
M. vanbaalenii PYR-1Mvan_0460-1e-4137.12% (299) hypothetical protein Mvan_0460

Closest Orthologs (e-value cutoff: 1e-4)
speciesidgenee-valueidentity (len)annotation
M. bovis AF2122 / 97Mb0778c-3e-0856.25% (48) transposase
M. gilvum PYR-GCKMflv_4763-7e-1328.83% (222) integrase catalytic subunit
M. tuberculosis H37RvRv2812-1e-1626.54% (324) transposase
M. leprae Br4923-----
M. abscessus ATCC 19977-----
M. marinum MMMAR_1373-1e-8538.98% (531) transposase for ISMyma05
M. avium 104MAV_3347-1e-1928.05% (328) transposase
M. smegmatis MC2 155MSMEG_6600-1e-2030.41% (319) transposase
M. thermoresistible (build 8)TH_3163-3e-3135.08% (305) PUTATIVE putative Integrase, catalytic region
M. ulcerans Agy99-----

CLUSTAL 2.0.9 multiple sequence alignment


Mvan_0573|M.vanbaalenii_PYR-1       -----------------MTQQLPNSPNDWVIEHRYRAVRQVL-DGVSKSQ
Mb0778c|M.bovis_AF2122/97           ------------------MKELS------VAEQRYQAVLAVISDGLSISQ
MMAR_1373|M.marinum_M               -----------------MLQELR------MSEMRYRAVLEVL-DGAPVTA
MAV_3347|M.avium_104                MKCELLKNAQLTPEVFVSHRNAP-----LSETGRLRLARCVVEDGWSLRR
MSMEG_6600|M.smegmatis_MC2_155      ----------------MVHRNAP-----LSETGRLRLARCVVDDGWSRRR
TH_3163|M.thermoresistible__bu      -----------------MAQKVT--------AMDIRMAAAVAGEIDNVAE
Rv2812|M.tuberculosis_H37Rv         ------------MAVGDDEEKVRAERARAIGLFRYQLIWEAADAAHSTKQ
Mflv_4763|M.gilvum_PYR-GCK          --------------MPASGDHRVDVAPLDCPVRRHESQRGQTAQGTRSRE
                                                        .              .              

Mvan_0573|M.vanbaalenii_PYR-1       ----------------VAQECGASRQSVHSWVIRYEALG-VAGLADRSRR
Mb0778c|M.bovis_AF2122/97           ----------------VAEKVGVSRQTLHTWLARYEAEG-LDGL------
MMAR_1373|M.marinum_M               ----------------VARRFGVSRQTVHAWLRRYAEEGAALNLEDRSSR
MAV_3347|M.avium_104                ----------------AAERFQVAVTTAQRWASRYRELG-PAGMADRSSR
MSMEG_6600|M.smegmatis_MC2_155      ----------------AAERFQVSVTTVCRWVNRYLELG-EAGMADRSSR
TH_3163|M.thermoresistible__bu      ----------------FCRRRKISRQTFYKFRRRFRDSG-IEGLQELSRR
Rv2812|M.tuberculosis_H37Rv         RGKMVRELASREHTDPFGRRVRISRQTIDRWIRGWRAGG----FDALVPN
Mflv_4763|M.gilvum_PYR-GCK          RPAQEAGRQPGPRHRHAQGDFGGKLLTPNRKRSAVIALRERFGVSERRAC
                                                              :                .      

Mvan_0573|M.vanbaalenii_PYR-1       PLTSPNELSPAVVAMVCELRR-----TYPRWGAQRIAHELAL--RGVDAP
Mb0778c|M.bovis_AF2122/97           ----------------------------------RIGTGTAL--------
MMAR_1373|M.marinum_M               PHRCPHQMPVEVEARVLTLRD-----AHPRWGPTRIVYELQR--DGVPVV
MAV_3347|M.avium_104                PLRSPNQTPTRTERRIIKVR------VLRRWGPARIAYLLGLNVSTVHRV
MSMEG_6600|M.smegmatis_MC2_155      PHHSPNRTPTRTERRIIGVR------VTRRWGPARIAYLLRLNVSTVHNV
TH_3163|M.thermoresistible__bu      PLTSPGQTPVEVEDLIVLRRKQLI-EQGRDHGAQSIVWSFERDGVTVPSV
Rv2812|M.tuberculosis_H37Rv         PRQCTPRTPAEVLELAVALRR---------ENPQRTAAAIRRILRTQLGW
Mflv_4763|M.gilvum_PYR-GCK          TVVGLHRSTMRLTPAPVTTEEAELRAWLRRFSTDRPRWGWRRAAKMARRA
                                                                                      

Mvan_0573|M.vanbaalenii_PYR-1       --PSRSS-VYRILVRHGLVAAQQQNHKR------KYRRWQRDAPMQLWQI
Mb0778c|M.bovis_AF2122/97           --------------------------------------------------
MMAR_1373|M.marinum_M               --PGRSS-VYRALVRNGRIDPAKRRRRRS-----DYKRWERGRPMELWQM
MAV_3347|M.avium_104                --LTRYK-LAKLRWLDRATGQVVRRMEAA-----CCGDLVHVDVKKLGKI
MSMEG_6600|M.smegmatis_MC2_155      --LRRYR-IARLRWLDRATGRVVRRMESA-----ACGDLVHADVKKLGKI
TH_3163|M.thermoresistible__bu      --STVWQRGWQILSRRGAITPQPQKRPKS-----ATKRFVFSCPNECWQS
Rv2812|M.tuberculosis_H37Rv         --APDERTLQRNFHRLGLTGATTG-SAPA-----VFGRFEAEHPNALWTG
Mflv_4763|M.gilvum_PYR-GCK          GWKANNKRIRRLWREEGLRVPQRRRKKRLTGIGVAVGAMSPIRPNVIWAM
                                                                                      

Mvan_0573|M.vanbaalenii_PYR-1       DIMGGVFLVDGRECKVVTGIDDHSRFVVMATVVAD-PGARAVCAAFTATM
Mb0778c|M.bovis_AF2122/97           --------------------------------------------------
MMAR_1373|M.marinum_M               DVVGGLHLRDGIEVKVVTGIDDNSRFVVSAKVVAR-ATARPVCAALLEAL
MAV_3347|M.avium_104                PAGGGWRMLGRTVGNRNAQADKTSGERSKHRHPLRGYHFLHTAIDAHSRL
MSMEG_6600|M.smegmatis_MC2_155      PAGGGWRMLGRTAGRKNSLADKSSGVKTRNGDPARGYHFLHSALDAHSRL
TH_3163|M.thermoresistible__bu      DWTG-WVLADGSPAGIAGSLDDHSRYVPALRACAGDADAQLVWETMLAGI
Rv2812|M.tuberculosis_H37Rv         DVLHGIRIDLR-KTYLFAFLDDHSRLVPGYR-WGHAEDTVRLAAALRPAL
Mflv_4763|M.gilvum_PYR-GCK          DFQFDTTADGR-TLKMLNVIDEFTR-EALAIEVDRAINADGVVDVLDRLA
                                                                                      

Mvan_0573|M.vanbaalenii_PYR-1       AIYGVPSEVLTDNGKQFTGRFTKP-YPAEVLFERICRENG----------
Mb0778c|M.bovis_AF2122/97           --------------------------------------------------
MMAR_1373|M.marinum_M               RRHGVPEQILTDNGKVFTGRFGPGGSSAEVLFDRVCVENG----------
MAV_3347|M.avium_104                AYSELLTDERKETAAAFWLRAQAWFTTCGFTVRKVLTDNGSCYRSHAFRD
MSMEG_6600|M.smegmatis_MC2_155      VYSEMLADERKDTASEFWKRANSWFFEQGVIVRTVLTDNGSCYRSHSFRE
TH_3163|M.thermoresistible__bu      AECGIPSMSLTDNGIVYTGRFHAHQSAFETNLRALG--------------
Rv2812|M.tuberculosis_H37Rv         ASRGVPNAVYVDNGSPYVDAWLLRACAKLG--------------------
Mflv_4763|M.gilvum_PYR-GCK          LTYGAPHYVRFDNGPEFVANAVADWCRFNS--------------------
                                                                                      

Mvan_0573|M.vanbaalenii_PYR-1       -----ITTRLTKPRSPTTTGKIERFHKTLRRELLDSAG-PFASI------
Mb0778c|M.bovis_AF2122/97           --------------------------------------------------
MMAR_1373|M.marinum_M               -----IGHLLTAPRSPTTTGKVERLHKTMRAEIFAEVDGVFDAI------
MAV_3347|M.avium_104                ALG-DIEHRRTRPYRPQTNGKVERFHRTLADEWA--YARLYRSD------
MSMEG_6600|M.smegmatis_MC2_155      ALGDDIEHRRTRPYRPQTNGKVERFHRTLADEWA--YARLYTSD------
TH_3163|M.thermoresistible__bu      -----VQTINATPFHPQTCGKIERFWQTLKKWLT--ARDPATTI------
Rv2812|M.tuberculosis_H37Rv         -----VRLVHSTPGRPQGRGKIERFFRTVREQFLVEITGEPDVVGRHYVA
Mflv_4763|M.gilvum_PYR-GCK          -----AGSLFIDPGSPWQNAWIESFNGRLRDELLN--LWRFDSL------
                                                                                      

Mvan_0573|M.vanbaalenii_PYR-1       --EVAQEAIDAWVHGYNHSRPHQSLGMATPATMFRPAP----IEVVPPVP
Mb0778c|M.bovis_AF2122/97           --------------------------------------------------
MMAR_1373|M.marinum_M               --AELQAAIDRWVQYYNTARPHQSLGMVAPAARFALAAGPDLSVVEPVAA
MAV_3347|M.avium_104                --AERCAEFPRWLHTYNHHRGHTALGGQPPATRVPNLSGQYI--------
MSMEG_6600|M.smegmatis_MC2_155      --EQRCQEYPRWLHTYNHHRGHTALGGQPPASRVPNLSGQYT--------
TH_3163|M.thermoresistible__bu      --AELNALLEQFRTFYNHQRPHRAHRGALPAEVFAAGDKARPADRPVPAP
Rv2812|M.tuberculosis_H37Rv         DLAELNRLFTAWVETVYHRSVHSETGQTPLARWSAGGPIPLPAPETLTEA
Mflv_4763|M.gilvum_PYR-GCK          --LEARVIIEDWRRDYNANRPHSAHGELTPAEFALQWTTTHQPQVA----
                                                                                      

Mvan_0573|M.vanbaalenii_PYR-1       VDTEPLTPDVVVPPRPRRHLPPATEHALIEVVHAVEWEAVLTPRARLLLP
Mb0778c|M.bovis_AF2122/97           --------------------------------------------------
MMAR_1373|M.marinum_M               VPAEGQHPGALVDLRDAGVRRWVNRHGSISVAG-----------------
MAV_3347|M.avium_104                --------------------------------------------------
MSMEG_6600|M.smegmatis_MC2_155      --------------------------------------------------
TH_3163|M.thermoresistible__bu      VIVSRHTVG--------------PTSGYVFVAP-----------------
Rv2812|M.tuberculosis_H37Rv         FLWEEHRR--------------VTKTATVSLHG-----------------
Mflv_4763|M.gilvum_PYR-GCK          --------------------------------------------------
                                                                                      

Mvan_0573|M.vanbaalenii_PYR-1       GDQQFKFTAALARREVTVWASDRSIHIVLDGTVIRTRPSRLSEHD-LRD-
Mb0778c|M.bovis_AF2122/97           --------------------------------------------------
MMAR_1373|M.marinum_M               --FRYRVPIVLAGEPVSVVVADNLVSIYHHDVLVASHVQHRKTDN-TTG-
MAV_3347|M.avium_104                --------------------------------------------------
MSMEG_6600|M.smegmatis_MC2_155      --------------------------------------------------
TH_3163|M.thermoresistible__bu      --YKVNVGLRWAGHECDIIRDGQHITILSGTTLVRSFTADPTRNY-QRGD
Rv2812|M.tuberculosis_H37Rv         --NRYEIDPALVGRKVELVFDPFDLTRIEVRLAGAPMRRAIPYHIGRHSH
Mflv_4763|M.gilvum_PYR-GCK          --------------------------------------------------
                                                                                      

Mvan_0573|M.vanbaalenii_PYR-1       LLRRGARIAGPEPARGAATIDILTTSAVIEVARTVSRDGCIGLGGDKVLL
Mb0778c|M.bovis_AF2122/97           --------------------------------------------------
MMAR_1373|M.marinum_M               VVRQGRRTARPVTSG-------------IVVTRVVDSNGDVSFAGTMYRA
MAV_3347|M.avium_104                --------------------------------------------------
MSMEG_6600|M.smegmatis_MC2_155      --------------------------------------------------
TH_3163|M.thermoresistible__bu      KTTRTYRTREPKPPS-----------------------------------
Rv2812|M.tuberculosis_H37Rv         PKAKPETPTAPPKPSGIDYAQLIETAHAAELARGVNYTALTGAADQIPGQ
Mflv_4763|M.gilvum_PYR-GCK          --------------------------------------------------
                                                                                      

Mvan_0573|M.vanbaalenii_PYR-1       ESTLVGQRVTLRFEGALMHVVANGRLVKTMPAPLPPDQRATLRGARPTSE
Mb0778c|M.bovis_AF2122/97           --------------------------------------------------
MMAR_1373|M.marinum_M               GRVWRGKQVEVSIVAESVQIACAGAIVR----------------------
MAV_3347|M.avium_104                --------------------------------------------------
MSMEG_6600|M.smegmatis_MC2_155      --------------------------------------------------
TH_3163|M.thermoresistible__bu      --------------------------------------------------
Rv2812|M.tuberculosis_H37Rv         LDLLTGQEAQPK--------------------------------------
Mflv_4763|M.gilvum_PYR-GCK          --------------------------------------------------
                                                                                      

Mvan_0573|M.vanbaalenii_PYR-1       PLPPPAPPNRAMRRVAANGTITIAGQRLRVGRSYQGRTVAVAIDDTVFRV
Mb0778c|M.bovis_AF2122/97           --------------------------------------------------
MMAR_1373|M.marinum_M               --------THAIRHDRAKEHGAFATPHGRPRKPRQDAPEGPGVKATPLRG
MAV_3347|M.avium_104                --------------------------------------------------
MSMEG_6600|M.smegmatis_MC2_155      --------------------------------------------------
TH_3163|M.thermoresistible__bu      --------------------------------------------------
Rv2812|M.tuberculosis_H37Rv         --------------------------------------------------
Mflv_4763|M.gilvum_PYR-GCK          --------------------------------------------------
                                                                                      

Mvan_0573|M.vanbaalenii_PYR-1       FIDGTEICTHARRTDTDITIFKAYPRRHGT
Mb0778c|M.bovis_AF2122/97           ------------------------------
MMAR_1373|M.marinum_M               RPEGRALTPAP-------------------
MAV_3347|M.avium_104                ------------------------------
MSMEG_6600|M.smegmatis_MC2_155      ------------------------------
TH_3163|M.thermoresistible__bu      ------------------------------
Rv2812|M.tuberculosis_H37Rv         ------------------------------
Mflv_4763|M.gilvum_PYR-GCK          ------------------------------