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VTQQLPNSPNDWVIEHRYRAVRQVLDGVSKSQVAQECGASRQSVHSWVIRYEALGVAGLADRSRRPLTSP NELSPAVVAMVCELRRTYPRWGAQRIAHELALRGVDAPPSRSSVYRILVRHGLVAAQQQNHKRKYRRWQR DAPMQLWQIDIMGGVFLVDGRECKVVTGIDDHSRFVVMATVVADPGARAVCAAFTATMAIYGVPSEVLTD NGKQFTGRFTKPYPAEVLFERICRENGITTRLTKPRSPTTTGKIERFHKTLRRELLDSAGPFASIEVAQE AIDAWVHGYNHSRPHQSLGMATPATMFRPAPIEVVPPVPVDTEPLTPDVVVPPRPRRHLPPATEHALIEV VHAVEWEAVLTPRARLLLPGDQQFKFTAALARREVTVWASDRSIHIVLDGTVIRTRPSRLSEHDLRDLLR RGARIAGPEPARGAATIDILTTSAVIEVARTVSRDGCIGLGGDKVLLESTLVGQRVTLRFEGALMHVVAN GRLVKTMPAPLPPDQRATLRGARPTSEPLPPPAPPNRAMRRVAANGTITIAGQRLRVGRSYQGRTVAVAI DDTVFRVFIDGTEICTHARRTDTDITIFKAYPRRHGT
Operon Prediction Model: Genebank
Paralogs
species | id | gene | e-value | identity (len) | annotation |
M. vanbaalenii PYR-1 | Mvan_0573 | - | - | 100% (597) | integrase catalytic subunit |
M. vanbaalenii PYR-1 | Mvan_0458 | - | e-108 | 62.18% (312) | integrase catalytic subunit |
M. vanbaalenii PYR-1 | Mvan_0460 | - | 1e-41 | 37.12% (299) | hypothetical protein Mvan_0460 |
Closest Orthologs (e-value cutoff: 1e-4)
species | id | gene | e-value | identity (len) | annotation |
M. bovis AF2122 / 97 | Mb0778c | - | 3e-08 | 56.25% (48) | transposase |
M. gilvum PYR-GCK | Mflv_4763 | - | 7e-13 | 28.83% (222) | integrase catalytic subunit |
M. tuberculosis H37Rv | Rv2812 | - | 1e-16 | 26.54% (324) | transposase |
M. leprae Br4923 | - | - | - | - | - |
M. abscessus ATCC 19977 | - | - | - | - | - |
M. marinum M | MMAR_1373 | - | 1e-85 | 38.98% (531) | transposase for ISMyma05 |
M. avium 104 | MAV_3347 | - | 1e-19 | 28.05% (328) | transposase |
M. smegmatis MC2 155 | MSMEG_6600 | - | 1e-20 | 30.41% (319) | transposase |
M. thermoresistible (build 8) | TH_3163 | - | 3e-31 | 35.08% (305) | PUTATIVE putative Integrase, catalytic region |
M. ulcerans Agy99 | - | - | - | - | - |
CLUSTAL 2.0.9 multiple sequence alignment Mvan_0573|M.vanbaalenii_PYR-1 -----------------MTQQLPNSPNDWVIEHRYRAVRQVL-DGVSKSQ Mb0778c|M.bovis_AF2122/97 ------------------MKELS------VAEQRYQAVLAVISDGLSISQ MMAR_1373|M.marinum_M -----------------MLQELR------MSEMRYRAVLEVL-DGAPVTA MAV_3347|M.avium_104 MKCELLKNAQLTPEVFVSHRNAP-----LSETGRLRLARCVVEDGWSLRR MSMEG_6600|M.smegmatis_MC2_155 ----------------MVHRNAP-----LSETGRLRLARCVVDDGWSRRR TH_3163|M.thermoresistible__bu -----------------MAQKVT--------AMDIRMAAAVAGEIDNVAE Rv2812|M.tuberculosis_H37Rv ------------MAVGDDEEKVRAERARAIGLFRYQLIWEAADAAHSTKQ Mflv_4763|M.gilvum_PYR-GCK --------------MPASGDHRVDVAPLDCPVRRHESQRGQTAQGTRSRE . . Mvan_0573|M.vanbaalenii_PYR-1 ----------------VAQECGASRQSVHSWVIRYEALG-VAGLADRSRR Mb0778c|M.bovis_AF2122/97 ----------------VAEKVGVSRQTLHTWLARYEAEG-LDGL------ MMAR_1373|M.marinum_M ----------------VARRFGVSRQTVHAWLRRYAEEGAALNLEDRSSR MAV_3347|M.avium_104 ----------------AAERFQVAVTTAQRWASRYRELG-PAGMADRSSR MSMEG_6600|M.smegmatis_MC2_155 ----------------AAERFQVSVTTVCRWVNRYLELG-EAGMADRSSR TH_3163|M.thermoresistible__bu ----------------FCRRRKISRQTFYKFRRRFRDSG-IEGLQELSRR Rv2812|M.tuberculosis_H37Rv RGKMVRELASREHTDPFGRRVRISRQTIDRWIRGWRAGG----FDALVPN Mflv_4763|M.gilvum_PYR-GCK RPAQEAGRQPGPRHRHAQGDFGGKLLTPNRKRSAVIALRERFGVSERRAC : . Mvan_0573|M.vanbaalenii_PYR-1 PLTSPNELSPAVVAMVCELRR-----TYPRWGAQRIAHELAL--RGVDAP Mb0778c|M.bovis_AF2122/97 ----------------------------------RIGTGTAL-------- MMAR_1373|M.marinum_M PHRCPHQMPVEVEARVLTLRD-----AHPRWGPTRIVYELQR--DGVPVV MAV_3347|M.avium_104 PLRSPNQTPTRTERRIIKVR------VLRRWGPARIAYLLGLNVSTVHRV MSMEG_6600|M.smegmatis_MC2_155 PHHSPNRTPTRTERRIIGVR------VTRRWGPARIAYLLRLNVSTVHNV TH_3163|M.thermoresistible__bu PLTSPGQTPVEVEDLIVLRRKQLI-EQGRDHGAQSIVWSFERDGVTVPSV Rv2812|M.tuberculosis_H37Rv PRQCTPRTPAEVLELAVALRR---------ENPQRTAAAIRRILRTQLGW Mflv_4763|M.gilvum_PYR-GCK TVVGLHRSTMRLTPAPVTTEEAELRAWLRRFSTDRPRWGWRRAAKMARRA Mvan_0573|M.vanbaalenii_PYR-1 --PSRSS-VYRILVRHGLVAAQQQNHKR------KYRRWQRDAPMQLWQI Mb0778c|M.bovis_AF2122/97 -------------------------------------------------- MMAR_1373|M.marinum_M --PGRSS-VYRALVRNGRIDPAKRRRRRS-----DYKRWERGRPMELWQM MAV_3347|M.avium_104 --LTRYK-LAKLRWLDRATGQVVRRMEAA-----CCGDLVHVDVKKLGKI MSMEG_6600|M.smegmatis_MC2_155 --LRRYR-IARLRWLDRATGRVVRRMESA-----ACGDLVHADVKKLGKI TH_3163|M.thermoresistible__bu --STVWQRGWQILSRRGAITPQPQKRPKS-----ATKRFVFSCPNECWQS Rv2812|M.tuberculosis_H37Rv --APDERTLQRNFHRLGLTGATTG-SAPA-----VFGRFEAEHPNALWTG Mflv_4763|M.gilvum_PYR-GCK GWKANNKRIRRLWREEGLRVPQRRRKKRLTGIGVAVGAMSPIRPNVIWAM Mvan_0573|M.vanbaalenii_PYR-1 DIMGGVFLVDGRECKVVTGIDDHSRFVVMATVVAD-PGARAVCAAFTATM Mb0778c|M.bovis_AF2122/97 -------------------------------------------------- MMAR_1373|M.marinum_M DVVGGLHLRDGIEVKVVTGIDDNSRFVVSAKVVAR-ATARPVCAALLEAL MAV_3347|M.avium_104 PAGGGWRMLGRTVGNRNAQADKTSGERSKHRHPLRGYHFLHTAIDAHSRL MSMEG_6600|M.smegmatis_MC2_155 PAGGGWRMLGRTAGRKNSLADKSSGVKTRNGDPARGYHFLHSALDAHSRL TH_3163|M.thermoresistible__bu DWTG-WVLADGSPAGIAGSLDDHSRYVPALRACAGDADAQLVWETMLAGI Rv2812|M.tuberculosis_H37Rv DVLHGIRIDLR-KTYLFAFLDDHSRLVPGYR-WGHAEDTVRLAAALRPAL Mflv_4763|M.gilvum_PYR-GCK DFQFDTTADGR-TLKMLNVIDEFTR-EALAIEVDRAINADGVVDVLDRLA Mvan_0573|M.vanbaalenii_PYR-1 AIYGVPSEVLTDNGKQFTGRFTKP-YPAEVLFERICRENG---------- Mb0778c|M.bovis_AF2122/97 -------------------------------------------------- MMAR_1373|M.marinum_M RRHGVPEQILTDNGKVFTGRFGPGGSSAEVLFDRVCVENG---------- MAV_3347|M.avium_104 AYSELLTDERKETAAAFWLRAQAWFTTCGFTVRKVLTDNGSCYRSHAFRD MSMEG_6600|M.smegmatis_MC2_155 VYSEMLADERKDTASEFWKRANSWFFEQGVIVRTVLTDNGSCYRSHSFRE TH_3163|M.thermoresistible__bu AECGIPSMSLTDNGIVYTGRFHAHQSAFETNLRALG-------------- Rv2812|M.tuberculosis_H37Rv ASRGVPNAVYVDNGSPYVDAWLLRACAKLG-------------------- Mflv_4763|M.gilvum_PYR-GCK LTYGAPHYVRFDNGPEFVANAVADWCRFNS-------------------- Mvan_0573|M.vanbaalenii_PYR-1 -----ITTRLTKPRSPTTTGKIERFHKTLRRELLDSAG-PFASI------ Mb0778c|M.bovis_AF2122/97 -------------------------------------------------- MMAR_1373|M.marinum_M -----IGHLLTAPRSPTTTGKVERLHKTMRAEIFAEVDGVFDAI------ MAV_3347|M.avium_104 ALG-DIEHRRTRPYRPQTNGKVERFHRTLADEWA--YARLYRSD------ MSMEG_6600|M.smegmatis_MC2_155 ALGDDIEHRRTRPYRPQTNGKVERFHRTLADEWA--YARLYTSD------ TH_3163|M.thermoresistible__bu -----VQTINATPFHPQTCGKIERFWQTLKKWLT--ARDPATTI------ Rv2812|M.tuberculosis_H37Rv -----VRLVHSTPGRPQGRGKIERFFRTVREQFLVEITGEPDVVGRHYVA Mflv_4763|M.gilvum_PYR-GCK -----AGSLFIDPGSPWQNAWIESFNGRLRDELLN--LWRFDSL------ Mvan_0573|M.vanbaalenii_PYR-1 --EVAQEAIDAWVHGYNHSRPHQSLGMATPATMFRPAP----IEVVPPVP Mb0778c|M.bovis_AF2122/97 -------------------------------------------------- MMAR_1373|M.marinum_M --AELQAAIDRWVQYYNTARPHQSLGMVAPAARFALAAGPDLSVVEPVAA MAV_3347|M.avium_104 --AERCAEFPRWLHTYNHHRGHTALGGQPPATRVPNLSGQYI-------- MSMEG_6600|M.smegmatis_MC2_155 --EQRCQEYPRWLHTYNHHRGHTALGGQPPASRVPNLSGQYT-------- TH_3163|M.thermoresistible__bu --AELNALLEQFRTFYNHQRPHRAHRGALPAEVFAAGDKARPADRPVPAP Rv2812|M.tuberculosis_H37Rv DLAELNRLFTAWVETVYHRSVHSETGQTPLARWSAGGPIPLPAPETLTEA Mflv_4763|M.gilvum_PYR-GCK --LEARVIIEDWRRDYNANRPHSAHGELTPAEFALQWTTTHQPQVA---- Mvan_0573|M.vanbaalenii_PYR-1 VDTEPLTPDVVVPPRPRRHLPPATEHALIEVVHAVEWEAVLTPRARLLLP Mb0778c|M.bovis_AF2122/97 -------------------------------------------------- MMAR_1373|M.marinum_M VPAEGQHPGALVDLRDAGVRRWVNRHGSISVAG----------------- MAV_3347|M.avium_104 -------------------------------------------------- MSMEG_6600|M.smegmatis_MC2_155 -------------------------------------------------- TH_3163|M.thermoresistible__bu VIVSRHTVG--------------PTSGYVFVAP----------------- Rv2812|M.tuberculosis_H37Rv FLWEEHRR--------------VTKTATVSLHG----------------- Mflv_4763|M.gilvum_PYR-GCK -------------------------------------------------- Mvan_0573|M.vanbaalenii_PYR-1 GDQQFKFTAALARREVTVWASDRSIHIVLDGTVIRTRPSRLSEHD-LRD- Mb0778c|M.bovis_AF2122/97 -------------------------------------------------- MMAR_1373|M.marinum_M --FRYRVPIVLAGEPVSVVVADNLVSIYHHDVLVASHVQHRKTDN-TTG- MAV_3347|M.avium_104 -------------------------------------------------- MSMEG_6600|M.smegmatis_MC2_155 -------------------------------------------------- TH_3163|M.thermoresistible__bu --YKVNVGLRWAGHECDIIRDGQHITILSGTTLVRSFTADPTRNY-QRGD Rv2812|M.tuberculosis_H37Rv --NRYEIDPALVGRKVELVFDPFDLTRIEVRLAGAPMRRAIPYHIGRHSH Mflv_4763|M.gilvum_PYR-GCK -------------------------------------------------- Mvan_0573|M.vanbaalenii_PYR-1 LLRRGARIAGPEPARGAATIDILTTSAVIEVARTVSRDGCIGLGGDKVLL Mb0778c|M.bovis_AF2122/97 -------------------------------------------------- MMAR_1373|M.marinum_M VVRQGRRTARPVTSG-------------IVVTRVVDSNGDVSFAGTMYRA MAV_3347|M.avium_104 -------------------------------------------------- MSMEG_6600|M.smegmatis_MC2_155 -------------------------------------------------- TH_3163|M.thermoresistible__bu KTTRTYRTREPKPPS----------------------------------- Rv2812|M.tuberculosis_H37Rv PKAKPETPTAPPKPSGIDYAQLIETAHAAELARGVNYTALTGAADQIPGQ Mflv_4763|M.gilvum_PYR-GCK -------------------------------------------------- Mvan_0573|M.vanbaalenii_PYR-1 ESTLVGQRVTLRFEGALMHVVANGRLVKTMPAPLPPDQRATLRGARPTSE Mb0778c|M.bovis_AF2122/97 -------------------------------------------------- MMAR_1373|M.marinum_M GRVWRGKQVEVSIVAESVQIACAGAIVR---------------------- MAV_3347|M.avium_104 -------------------------------------------------- MSMEG_6600|M.smegmatis_MC2_155 -------------------------------------------------- TH_3163|M.thermoresistible__bu -------------------------------------------------- Rv2812|M.tuberculosis_H37Rv LDLLTGQEAQPK-------------------------------------- Mflv_4763|M.gilvum_PYR-GCK -------------------------------------------------- Mvan_0573|M.vanbaalenii_PYR-1 PLPPPAPPNRAMRRVAANGTITIAGQRLRVGRSYQGRTVAVAIDDTVFRV Mb0778c|M.bovis_AF2122/97 -------------------------------------------------- MMAR_1373|M.marinum_M --------THAIRHDRAKEHGAFATPHGRPRKPRQDAPEGPGVKATPLRG MAV_3347|M.avium_104 -------------------------------------------------- MSMEG_6600|M.smegmatis_MC2_155 -------------------------------------------------- TH_3163|M.thermoresistible__bu -------------------------------------------------- Rv2812|M.tuberculosis_H37Rv -------------------------------------------------- Mflv_4763|M.gilvum_PYR-GCK -------------------------------------------------- Mvan_0573|M.vanbaalenii_PYR-1 FIDGTEICTHARRTDTDITIFKAYPRRHGT Mb0778c|M.bovis_AF2122/97 ------------------------------ MMAR_1373|M.marinum_M RPEGRALTPAP------------------- MAV_3347|M.avium_104 ------------------------------ MSMEG_6600|M.smegmatis_MC2_155 ------------------------------ TH_3163|M.thermoresistible__bu ------------------------------ Rv2812|M.tuberculosis_H37Rv ------------------------------ Mflv_4763|M.gilvum_PYR-GCK ------------------------------