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VRLAAALRPALASRGVPNAVYVDNGSPYVDAWLLRACAKLGVRLVHSTPGRPQGRGKIERFFRTVREQFL VEITGEPDVVGRHYVADLAELNRLFTAWVETVYHRSVHSETGQTPLARWSAGGPIPLPAPETLTEAFLWE EHRRVTKTATVSLHGNRYEIDPALVGRKVELVFDPFDLTRIEVRLAGAPMGRAIPYHIGRHSHPKAKPET PTAPPKPSGIDYAQLIETAHAAELARGVNYTALTGAADQIPGQLDLLTGQEAQPK
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb2836 | - | - | 100% (265) | transposase |
| M. bovis AF2122 / 97 | Mb3661 | - | 4e-05 | 29.41% (102) | putative transposase |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. gilvum PYR-GCK | Mflv_3183 | - | 1e-06 | 26.03% (219) | integrase catalytic subunit |
| M. tuberculosis H37Rv | Rv2812 | - | 1e-154 | 99.62% (265) | transposase |
| M. leprae Br4923 | - | - | - | - | - |
| M. abscessus ATCC 19977 | MAB_4893c | - | 9e-10 | 29.33% (150) | integrase/transposase |
| M. marinum M | MMAR_4106 | - | 9e-10 | 26.80% (194) | transposase for ISMyma05 |
| M. avium 104 | - | - | - | - | - |
| M. smegmatis MC2 155 | - | - | - | - | - |
| M. thermoresistible (build 8) | TH_3163 | - | 8e-07 | 28.79% (132) | PUTATIVE putative Integrase, catalytic region |
| M. ulcerans Agy99 | - | - | - | - | - |
| M. vanbaalenii PYR-1 | Mvan_2928 | - | 5e-84 | 60.29% (277) | integrase catalytic subunit |
CLUSTAL 2.0.9 multiple sequence alignment
Mb2836|M.bovis_AF2122/97 --------------------------------------------------
Rv2812|M.tuberculosis_H37Rv --------------------------------------------------
Mvan_2928|M.vanbaalenii_PYR-1 --------------------------------------------------
MMAR_4106|M.marinum_M --------------------------------------------------
TH_3163|M.thermoresistible__bu --------------------------------------------------
Mflv_3183|M.gilvum_PYR-GCK --------------------------------------------------
MAB_4893c|M.abscessus_ATCC_199 MTAGAERFGIGTRFVYEGQIIDVVQLRSTPKGPEVIASNGLEVMHVALKE
Mb2836|M.bovis_AF2122/97 --------------------------------------------------
Rv2812|M.tuberculosis_H37Rv -------MAVGDDEEKVRAERARAIGLFRYQLIWEAADAAHSTKQRGKMV
Mvan_2928|M.vanbaalenii_PYR-1 ----------MSLEEHKRRERANAIGLFRYQLICPALEDGLSTRQRGRLV
MMAR_4106|M.marinum_M -----------------------------------MLQELRMSEMRYRAV
TH_3163|M.thermoresistible__bu -----------------------------------MAQKVTAMDIR-MAA
Mflv_3183|M.gilvum_PYR-GCK -------MLWSVEALEGVPEEVADRARWWEQHIVEVLTGRRPESPPGQPI
MAB_4893c|M.abscessus_ATCC_199 LLQSSRARLIPTEDGPSADDEQETAAMMLAQLSKAELKTVRERAAHVREV
Mb2836|M.bovis_AF2122/97 --------------------------------------------------
Rv2812|M.tuberculosis_H37Rv RELASREHTDPF-----------GRRV-----------RISRQTIDRWIR
Mvan_2928|M.vanbaalenii_PYR-1 REIAERRHIDPF-----------GTQV-----------QIARATLDRWIR
MMAR_4106|M.marinum_M LEVLDGAPVTAV-----------ARRF-----------GVSRQTVHAWLR
TH_3163|M.thermoresistible__bu AVAGEIDNVAEF-----------CRRR-----------KISRQTFYKFRR
Mflv_3183|M.gilvum_PYR-GCK RPEFDPAVRSLR-----------QRELTKLEELRAAGHDLALITLQRQRS
MAB_4893c|M.abscessus_ATCC_199 LTGFRRGSEHIKEPDEPRPGFDPCGALADRYKAKAEQLNTSVRTVQRWVS
Mb2836|M.bovis_AF2122/97 --------------------------------------------------
Rv2812|M.tuberculosis_H37Rv GWRAG----GFDALVPNPRQCTPRTPAEVLELAVALR-----------RE
Mvan_2928|M.vanbaalenii_PYR-1 RYRGG----GFEALVPEPRRLATRTDTQVLELAASLK-----------RE
MMAR_4106|M.marinum_M RYAEEGAALNLEDRSSRPHRCPHQMPVEVEARVLTLR-----------DA
TH_3163|M.thermoresistible__bu RFRDSG-IEGLQELSRRPLTSPGQTPVEVEDLIVLRRK-------QLIEQ
Mflv_3183|M.gilvum_PYR-GCK RYEAKGLLGLVDGRYLAKRPVLGRVDERVVAVVRRLIDNETELSTGTVSR
MAB_4893c|M.abscessus_ATCC_199 NYRRFGEAGLVDHRKPRQLGVDQRWVDEALAVMVERTNE-----SRCTRK
Mb2836|M.bovis_AF2122/97 --------------------------------------------------
Rv2812|M.tuberculosis_H37Rv NPQR-TAAAIRRILRTQLGWAPDERTLQR---NFHRL-------GLTGAT
Mvan_2928|M.vanbaalenii_PYR-1 NPAR-TVAQVARILRTATGWAPSESTLLR---HFHRC-------ELMGPA
MMAR_4106|M.marinum_M HPRWGPTRIVYELQRDVVPVVPGRSSVYR---ALVRN-------GRIDPA
TH_3163|M.thermoresistible__bu GRDHGAQSIVWSFERDGVTVPSVSTVWQRGWQILSRR-------GAITPQ
Mflv_3183|M.gilvum_PYR-GCK LQRKLEKALLAEYGPDDAPKAPSQATFYRLVKRLEEGKHTF-GSARTRRS
MAB_4893c|M.abscessus_ATCC_199 LVMWEATKRIEQRYGTGSVQIPSKTTAYKVLKILETRYPAFRLSAARNRD
Mb2836|M.bovis_AF2122/97 --------------------------------------------------
Rv2812|M.tuberculosis_H37Rv TG-SAPAVFGRFEAEHPNALWTGD------------------VLHGIRID
Mvan_2928|M.vanbaalenii_PYR-1 AG-QSAEVFGRFEAADPNELWVGD------------------ALHGPRVG
MMAR_4106|M.marinum_M KRRRRRSDYKRWERGRPMELWQMD------------------VVGGLHLR
TH_3163|M.thermoresistible__bu PQKRPKSATKRFVFSCPNECWQSD------------------WTG-WVLA
Mflv_3183|M.gilvum_PYR-GCK LAKQPDGPFGTVTAARPGEMVEIDSTPLDVRVVLDDGV-VDRVELTAMVD
MAB_4893c|M.abscessus_ATCC_199 IAGRPQEPYGKLKPTRPGEFMLMDTTPLDVFAYDPATSRSIRVELTVAMD
Mb2836|M.bovis_AF2122/97 -------------------------------MRLAAALRPALASRG----
Rv2812|M.tuberculosis_H37Rv L-RKTYLFAFLDDH-SRLVPGYRWGH-AEDTVRLAAALRPALASRG----
Mvan_2928|M.vanbaalenii_PYR-1 D-RKTYLFAFLDDH-SRLVVGHRFGF-AEDTVRLAAALKPALAARG----
MMAR_4106|M.marinum_M DGIEVKVVTGIDDN-SRFVVSAKVVA-RATARPVCAALLEALRRHG----
TH_3163|M.thermoresistible__bu DGSPAGIAGSLDDH-SRYVPALRACAGDADAQLVWETMLAGIAECG----
Mflv_3183|M.gilvum_PYR-GCK NVTRSIPAAVLRPT-TKAVDAALLLAKALTPEPMRPGWSDALRLSRSVLP
MAB_4893c|M.abscessus_ATCC_199 WYTRCITALRLTPVSTKAVDVAAVLYQLYRPLPAGPNWPDHACWPEHGVP
Mb2836|M.bovis_AF2122/97 ------------------------------------VPNAVYVDNGSPYV
Rv2812|M.tuberculosis_H37Rv ------------------------------------VPNAVYVDNGSPYV
Mvan_2928|M.vanbaalenii_PYR-1 ------------------------------------VPAGIYVDNGSAFV
MMAR_4106|M.marinum_M ------------------------------------VPEQILTDNGKVFT
TH_3163|M.thermoresistible__bu ------------------------------------IPSMSLTDNGIVYT
Mflv_3183|M.gilvum_PYR-GCK HRRLTDIDQRLAD----------------AAARPVIAPETIVCDHGKAFL
MAB_4893c|M.abscessus_ATCC_199 RSVLIDPDAIDYTGAKYPQKHEQQAGPPTRSGGPAIVPETIVIDHGKIYV
* *:* :
Mb2836|M.bovis_AF2122/97 ----------DAWLLRACAKLGVRLVHSTPGRPQGRGKIERFFRTVREQF
Rv2812|M.tuberculosis_H37Rv ----------DAWLLRACAKLGVRLVHSTPGRPQGRGKIERFFRTVREQF
Mvan_2928|M.vanbaalenii_PYR-1 ----------DAWLLRACAKLGIRLVHSAPGRPQGRGKIERFFRTVREQF
MMAR_4106|M.marinum_M GRFGPGGSSAEVLFDRVCVENGIGHLLTAPRSPTTTGKVERLHKTMRAEI
TH_3163|M.thermoresistible__bu G----RFHAHQSAFETNLRALGVQTINATPFHPQTCGKIERFWQTLKKWL
Mflv_3183|M.gilvum_PYR-GCK S----------KTFEQACCSLGINLQPAHPDQPTDKPKVERTLQSVGTLF
MAB_4893c|M.abscessus_ATCC_199 S----------EHINSVCARMGISIQPVRLGEGRDKGPVERFFRSVRQGV
: *: :** ::: .
Mb2836|M.bovis_AF2122/97 LVEITG--------EPDVVGRHYVADLAELNRLFTAWVETVYHRSVHSET
Rv2812|M.tuberculosis_H37Rv LVEITG--------EPDVVGRHYVADLAELNRLFTAWVETVYHRSVHSET
Mvan_2928|M.vanbaalenii_PYR-1 LVEVTDTT----AEDLTAAGVDHTGALLELNRLFMAWVETEYHRRTHTET
MMAR_4106|M.marinum_M FAEVDG----------------VFDAIAELQAAIDRWVQYYNTARPHQSL
TH_3163|M.thermoresistible__bu TARDPA------------------TTIAELNALLEQFRTFYNHQRPHRAH
Mflv_3183|M.gilvum_PYR-GCK AQYVAGYVGSSVERRGKNADQDAVWSLVELQALLDEWLVAVWQNRPHDGL
MAB_4893c|M.abscessus_ATCC_199 LEFLPGYAGPDIASRGLDPQAQAELYIDELEELLRQWVAVYYHHRPHSGL
: **: : : *
Mb2836|M.bovis_AF2122/97 GQT--------PLARWSAG--------GPIP-LPAPETLTEAFLWEEHR-
Rv2812|M.tuberculosis_H37Rv GQT--------PLARWSAG--------GPIP-LPAPETLTEAFLWEEHR-
Mvan_2928|M.vanbaalenii_PYR-1 GQS--------PLARWETGW----DRLGALPALPTAADLTEAFLWSEFR-
MMAR_4106|M.marinum_M GMVA-------PAARFALAAGPDLSVVEPVAAVPAEGQHPGALVDLRDAG
TH_3163|M.thermoresistible__bu RGAL-------PAEVFAAG----------DKARPADRPVPAPVIVSRHT-
Mflv_3183|M.gilvum_PYR-GCK RDPVTPGKALTPNEKFAALVEVAGYVPVPLSADAYIELLPATWRTIGSAG
MAB_4893c|M.abscessus_ATCC_199 VDPHLPSARMSPAQMYEHGLAGAGFIEIPRDPDLAYEFLRPELRTIQPYG
* :
Mb2836|M.bovis_AF2122/97 ---RVTKTATVSLHGN-RYEIDPALVG----RKVELVFDPFDLTRIEVRL
Rv2812|M.tuberculosis_H37Rv ---RVTKTATVSLHGN-RYEIDPALVG----RKVELVFDPFDLTRIEVRL
Mvan_2928|M.vanbaalenii_PYR-1 ---VVTKTATVSLHSN-IYRVDPALAG----RRVELVFSPFDLQAIEVRH
MMAR_4106|M.marinum_M VRRWVNRHGSISVAGF-RYRVPIVLAG----EPVSVVVADN---LVSIYH
TH_3163|M.thermoresistible__bu ---VGPTSGYVFVAPY-KVNVGLRWAG----HECDIIRDGQ---HITILS
Mflv_3183|M.gilvum_PYR-GCK IRVNHRTYDARALNPYRRVDSGVRSRN----GRWEVHYDPYDVSQIWVRN
MAB_4893c|M.abscessus_ATCC_199 VQVDNRIYRGLPQDETHILGELANLPSPYGRHRWPVYSDPDDIRYVYVRH
. : : :
Mb2836|M.bovis_AF2122/97 AGAPMGRAIPYHIGRHSHPKAKP----ETP-TAPPKPSGIDYAQLIETAH
Rv2812|M.tuberculosis_H37Rv AGAPMRRAIPYHIGRHSHPKAKP----ETP-TAPPKPSGIDYAQLIETAH
Mvan_2928|M.vanbaalenii_PYR-1 QDRSYGPAVAHTITRHAHPKARP----ETRGEAPPAATGIDYLALTAANH
MMAR_4106|M.marinum_M HDVLVASHVQHRKTDNTTGVVRQ----GRR-TARPVTSGIVVTRVVDSNG
TH_3163|M.thermoresistible__bu GTTLVRSFTADPTRNYQRGDKTT----RTYRTREPKPPS-----------
Mflv_3183|M.gilvum_PYR-GCK HHDDGWITATWTHMRTAAVPFGD----TVWKQAQAIVAERGADPVTEAEI
MAB_4893c|M.abscessus_ATCC_199 PDNRRWHTLTWELADALNMPMSDERLSYLRRQAAQQHEEFDDRLILDELL
Mb2836|M.bovis_AF2122/97 A---AELARG--VNYTALTG---------AADQIPGQLDL----------
Rv2812|M.tuberculosis_H37Rv A---AELARG--VNYTALTG---------AADQIPGQLDL----------
Mvan_2928|M.vanbaalenii_PYR-1 H---AQLRDDERIGYHALYGTQAATDDTAGDDQVLGQLSIT-----DLEP
MMAR_4106|M.marinum_M D---VSFAGTMYRAGRVWRGKQVEVSIVAESVQIACAGAIVRTHAIRHDR
TH_3163|M.thermoresistible__bu --------------------------------------------------
Mflv_3183|M.gilvum_PYR-GCK A---AAADALLDRAERGPDTQQDPPAARRAAARARSIPEPS----WPHPS
MAB_4893c|M.abscessus_ATCC_199 SGWNLSMGTSTTEKRIALRMSRPHATLSYQIQQIGPRPSRPETGQLAPDT
Mb2836|M.bovis_AF2122/97 --LTGQEAQPK---------------------------------------
Rv2812|M.tuberculosis_H37Rv --LTGQEAQPK---------------------------------------
Mvan_2928|M.vanbaalenii_PYR-1 GGRTGASADHEGEVSA----------------------------------
MMAR_4106|M.marinum_M AKEHGAFATPHGRPRKPRQDAPDGPGAKATPLRGRPEGRALTPAP-----
TH_3163|M.thermoresistible__bu --------------------------------------------------
Mflv_3183|M.gilvum_PYR-GCK VEGTNQNQEPSEVSTDRPANSDDDDLADVIPLPVFDARKEAEQWHW----
MAB_4893c|M.abscessus_ATCC_199 APEPLLAQGTSAIAADIQIEGTAARCRAAAQASDDDDDDELDDFYAGALE
Mb2836|M.bovis_AF2122/97 --
Rv2812|M.tuberculosis_H37Rv --
Mvan_2928|M.vanbaalenii_PYR-1 --
MMAR_4106|M.marinum_M --
TH_3163|M.thermoresistible__bu --
Mflv_3183|M.gilvum_PYR-GCK --
MAB_4893c|M.abscessus_ATCC_199 EA