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M. thermoresistible (build 8) TH_2617 (-)

annotation: virulence factor Mce family protein
coordinates: 329039 - 330070
length: 344

aa seq not available

Operon Prediction Model: Genebank

Paralogs
speciesidgenee-valueidentity (len)annotation
M. thermoresistible (build 8)TH_2617--100% (344)virulence factor Mce family protein
M. thermoresistible (build 8)TH_3551-e-12763.56% (343) PUTATIVE virulence factor Mce family protein
M. thermoresistible (build 8)TH_4123-2e-7547.35% (321) PUTATIVE virulence factor Mce family protein

Closest Orthologs (e-value cutoff: 1e-4)
speciesidgenee-valueidentity (len)annotation
M. bovis AF2122 / 97Mb0605mce2B1e-11960.64% (343) MCE-family protein MCE2B
M. gilvum PYR-GCKMflv_0710-1e-12663.85% (343) virulence factor Mce family protein
M. tuberculosis H37RvRv0170mce1B1e-11859.54% (346) MCE-family protein MCE1B
M. leprae Br4923MLBr_02590mce1B1e-11659.54% (346) putative secreted protein
M. abscessus ATCC 19977MAB_4152c-1e-5838.54% (314) MCE-family protein
M. marinum MMMAR_0413mce1B1e-11760.40% (346) MCE-family protein Mce1B
M. avium 104MAV_4550-1e-12262.39% (343) virulence factor Mce family protein
M. smegmatis MC2 155MSMEG_0135-1e-13166.47% (343) virulence factor Mce family protein
M. ulcerans Agy99MUL_1063mce1B1e-11760.12% (346) MCE-family protein Mce1B
M. vanbaalenii PYR-1Mvan_0135-1e-12764.43% (343) virulence factor Mce family protein

CLUSTAL 2.0.9 multiple sequence alignment


Mflv_0710|M.gilvum_PYR-GCK          MKITGTAIKLGAFALVLLMFTAIIIVVFGQMRFDRTTGYSAIFSNASGLR
Mvan_0135|M.vanbaalenii_PYR-1       MKITGTAIKLGAFSLVLLMFTAIIIVVFGQMRFDRTTGYSAIFSSASGLR
MSMEG_0135|M.smegmatis_MC2_155      MSIKGTLFKLGIFSLVLLTFTALIFVVFGQIRFNRTTEYSAIFKNVSGLR
TH_2617|M.thermoresistible__bu      MRITGVAVRLGIFSAILLLFTALIIVVFGQVRFDRTVRYAAEFSNVSGLR
Mb0605|M.bovis_AF2122/97            MKTTGTTIKLGIVWLVLSVFTVMIIVVFGQVRFHHTTGYSAVFTHVSGLR
MAV_4550|M.avium_104                MRITGTAVKLVVFWSVLAMFTVMIIVVFGQVRFDRTTGYSAVFTDAGGLR
MMAR_0413|M.marinum_M               MKITGTAIRLGIFSLVLMLFSVMIIIVFGQIRFDRTYAYSAEFSNASGLR
MUL_1063|M.ulcerans_Agy99           MKITGTAIRLGIFSLVLMLFSVMIIIVFGQIRFDRTYAYSAEFSNASGLR
MLBr_02590|M.leprae_Br4923          MKLTGTVVRLSIFSLVLLLFTVMIIVVFGQMRFGRTNGYTAEFTNISGLR
Rv0170|M.tuberculosis_H37Rv         MKITGTVVKLGIVSVVLLFFTVMIIVIFGQMRFDRTNGYTAEFSNVSGLR
MAB_4152c|M.abscessus_ATCC_199      MKR-ATQIKVIVFTVVMLLVAAGLIITFGEFRFGSGKRYHAMFSTASDLR
                                    *   .. .::  .  ::  .:. ::: **:.**     * * *.  ..**

Mflv_0710|M.gilvum_PYR-GCK          SGQFVRASGVEVGKVKGVELIDNGSKVRVDFDVDRSLELFDETTASVRYL
Mvan_0135|M.vanbaalenii_PYR-1       PGQFVRASGVEVGKVKGVELIEGGSKVRVDFNVDRSLELFDESTASIRYL
MSMEG_0135|M.smegmatis_MC2_155      DGQFVRAAGVEVGKVKSVDLINGGEQAEVKFTVERSLPLFQETTAAIRYQ
TH_2617|M.thermoresistible__bu      AGQFVRASGVEVGKVVSVTVGGGDRPVRVEFAVDHTVPLFASTTAAIRYQ
Mb0605|M.bovis_AF2122/97            AGQFVRAAGVEVGKVAKVTLIDGDKQVLVDFTVDRSLSLDQATTASIRYL
MAV_4550|M.avium_104                AGQFVRASGVEVGKVAAVTLSGKDSRVLVEFNVDRSLALDQGTTASIRYL
MMAR_0413|M.marinum_M               PGQFVRASGVEIGKVKSVSLIDGGKRVRVNFDVDRSVPLYQSTSAQIRYL
MUL_1063|M.ulcerans_Agy99           PGQFVRASGVEIGKVKSVSLIDGGKRVRVNFDVDRSVPLYQSTSAQIRYL
MLBr_02590|M.leprae_Br4923          TGQFVRASGVEVGKVNSVALINGGTRVRVKFNVDRSVPLYQSTTAQIRYL
Rv0170|M.tuberculosis_H37Rv         QGQFVRASGVEIGKVKALHLVDGGRRVRVEFNIDRSVPLYQSTTAQIRYS
MAB_4152c|M.abscessus_ATCC_199      SGQKVRIAGVPVGRVKNVSLN-RDNSVEVTFDVDSKYQLYSSSRAIIRYE
                                     ** ** :** :*:*  : :   .  . * * :: .  *   : * :** 

Mflv_0710|M.gilvum_PYR-GCK          NLIGDRYLELARG---DSNTRLAAGGTIPVERTQPALDLDALIGGFRPVF
Mvan_0135|M.vanbaalenii_PYR-1       NLIGDRYLELARG---ESNTRMAAGGTIPIERTQPALDLDALIGGFRPVF
MSMEG_0135|M.smegmatis_MC2_155      DLIGNRYLELKRG---DSDQILPPGSTIPVERTEPALDLDALVGGFRPLF
TH_2617|M.thermoresistible__bu      DLIGNRYLELQPG---TDRRPLPPGSTIPVERTRPALDLDALIGGFRPLL
Mb0605|M.bovis_AF2122/97            NLIGDRYLELGRG---HSGQRLAPGATIPLEHTHPALDLDALLGGFRPLF
MAV_4550|M.avium_104                NLIGDRYLELKRG---TSGRRLPPGGRIPVEHTQPALDLDALIGGFRPLF
MMAR_0413|M.marinum_M               DLIGNRYLELKRGEGDGSDRIMPPGGFIPLSRTSPALDLDALIGGFKPVF
MUL_1063|M.ulcerans_Agy99           DLIGNRYLELKRGEGDGSDRIMPPGGFIPLSRTSPALDLDALIGGFKPVF
MLBr_02590|M.leprae_Br4923          DLIGNRYLELKHGEGQGSEKIMPAGGLIPLSRTSPALDLDALIGGFKPLF
Rv0170|M.tuberculosis_H37Rv         DLIGNRYVELKRGEGKGANDLLPPGGLIPLSRTSPALDLDALIGGFKPVF
MAB_4152c|M.abscessus_ATCC_199      NLVGDRYLEITAG--PGELHKLPDGGTLDKEHTQPALDLDALLGGLRPVL
                                    :*:*:**:*:  *        :. *. :  .:* ********:**::*::

Mflv_0710|M.gilvum_PYR-GCK          QSLDPEKVNTIAQSLITVFQGQGGTINDILDQTASLTSALADRDQAIGEV
Mvan_0135|M.vanbaalenii_PYR-1       QSLEPEKVNTIAQSIITVFQGQGGTINDILDQTASLTSALADRDQAIGEV
MSMEG_0135|M.smegmatis_MC2_155      RSLEPEKVNTIATSLITIFQGQGGTINDILDQTAQLTASLADRDQAIGEV
TH_2617|M.thermoresistible__bu      RSLDPGRVNSIAESIVVALEGRGDTLGQILDHTAQLTSRLAERDQTIGEL
Mb0605|M.bovis_AF2122/97            QTLDPDKVNSIASSIITVFQGQGATINDILDQTASLTATLADRDHAIGEV
MAV_4550|M.avium_104                QALDPNKVNSIAQSIITVFQGQGATITDILDQTAALTAALADRDKAIGEV
MMAR_0413|M.marinum_M               RALDPDKVNTIASALVTVFQGQGGTINDILDQTAQLTSQLAERDQAIGEV
MUL_1063|M.ulcerans_Agy99           RALDPDKVNTIASALVTVFQGQGGTINDILDQTAWLTSQLAERDQAIGEV
MLBr_02590|M.leprae_Br4923          RALDPDKINTIASAIVAAFQGQGGTINDILDQTAQLTTAIGERDQAIGEV
Rv0170|M.tuberculosis_H37Rv         RALDPAKVNNIANALITVFQGQGGTINDILDQTAQLTSQIAERDQAIGEV
MAB_4152c|M.abscessus_ATCC_199      KGFDAAKVNEISNAFIQILQGQGGTLSQLLGDTSSFTSGLAERDQLIGDV
                                    : ::. ::* *: :::  ::*:* *: ::*..*: :*: :.:**: **::

Mflv_0710|M.gilvum_PYR-GCK          VTNLNTVLDTTVRHQQEFDDTVKNFEVLITGLKNRADPLAESVADISDAA
Mvan_0135|M.vanbaalenii_PYR-1       ITNLNTVLDTTVRHQQEFDDTVKNFEVLITGLKNRADPIATSVADISDAA
MSMEG_0135|M.smegmatis_MC2_155      IKNLNTVLDTTVRHQKQFDETLVNFETLITGLKNRADPIATSVADISDAA
TH_2617|M.thermoresistible__bu      IADLNVVLDTTVRYQEEFDDTLADFETLITALRNRADPLADAVAHISDAA
Mb0605|M.bovis_AF2122/97            VNNLNTVLATTVKHQTEFDRTVDKLEVLITGLKNRADPLAAAAAHISSAA
MAV_4550|M.avium_104                INNLNTVLATTVKHEKEFDRTVDKLELLITGLKNRADPLAAAAAHISDAA
MMAR_0413|M.marinum_M               IKNLNTVLDATVRHRKDFDQTVNNLEVLITGLNEHRDDLSGGIAHVSNAA
MUL_1063|M.ulcerans_Agy99           IKNLNTVLDATVRHRKDFDQTVNNLEVLITGLNEHRDDLSGGIAHVSNAA
MLBr_02590|M.leprae_Br4923          VKNLNVVLDTTVRHRKEFDQTVNNLEILITGLKDHGDQLAGSFAHISNAA
Rv0170|M.tuberculosis_H37Rv         VKNLNIVLDTTVKHRKEFDETVNNLENLITGLRNHSDQLAGGLAHISNGA
MAB_4152c|M.abscessus_ATCC_199      INHLNEVLATVDSKSTQFSSSVDQLQQLISGLAQQRDVVAGALPPLASTA
                                    : .** ** :.     :*. :: .:: **:.* :: * :: . . ::. *

Mflv_0710|M.gilvum_PYR-GCK          GTIGDLLADNRPLLQSTISKLEILNQPLVDQKDQLNQLLEQIPDALAIIG
Mvan_0135|M.vanbaalenii_PYR-1       GTIGDLLADNRPLLKDTVSKLEILNQPLVDQRDQLNDLLVKLPDALAIIG
MSMEG_0135|M.smegmatis_MC2_155      GSLADLLSDNRPLLKDTIGYLDVIQAPLVEQKQEVSDILVQMPQALKIIG
TH_2617|M.thermoresistible__bu      GTVGDLLADERPVLKDTVGHLENVAQPLIDDISNLDDLLIRWPEAFKTIG
Mb0605|M.bovis_AF2122/97            GTLADLLGADRPLLHSSFGHLEGIQQPLIDELAELDHVLGKLPDAYRIIG
MAV_4550|M.avium_104                ATVAGLLGEDRPSLHGTLGHLEGIQQALINDLPTADNVLEKLPGAFRVIG
MMAR_0413|M.marinum_M               GTVADLLGEDRALLHKTVNYLDAVQQPLIDQRQELADFLHKVPTALNMIG
MUL_1063|M.ulcerans_Agy99           GTVADLLGEDRALLHKTVNYLDAVQQPLIDQRQELADFLHKVPTALNMIG
MLBr_02590|M.leprae_Br4923          GTVANLLAEDHALLHKSINYLDGIQQPLIDQRLQLEDYLHKLPTVLNQIG
Rv0170|M.tuberculosis_H37Rv         GTVADLLAENRTLVRKAVSYLDAIQQPVIDQRVELDDLLHKTPTALTALG
MAB_4152c|M.abscessus_ATCC_199      SSLESVLKDTRPYIKGTIEQARQLATRVDERKADVNVVVENLAENYLRLN
                                    .:: .:*   :. :: :.     :   : :        : . .     :.

Mflv_0710|M.gilvum_PYR-GCK          RSGGIYGDFFNFYACDVTLKLNGLQPGGPVRTVRVWSQPT-GRCTPQ--
Mvan_0135|M.vanbaalenii_PYR-1       RSGGVYGDFFNFYACDVTLKLNGLQPGGPVRTVKVWSQPS-GRCTPQ--
MSMEG_0135|M.smegmatis_MC2_155      RAGGIYGDFFNFYACDLTLKLNGLQPGGPVRTVRITTQPS-GRCTPK--
TH_2617|M.thermoresistible__bu      RAGGIYGDFFNFYLCDLNLKLNGLQPGGPVRTVRITHQPS-GRCTPK--
Mb0605|M.bovis_AF2122/97            RAGGIYGDFFNFYLCDISLKVNGLQPGGPVRTVKLFGQPT-GRCTPQ--
MAV_4550|M.avium_104                RAGGIYGDFYNFYLCDISIKVNGLQPGGPVRTIKLFGQPT-GRCTPQ--
MMAR_0413|M.marinum_M               RAIGSYGDFVNFYSCDISLKINGLQPGGPVRTVRLFSQPT-GRCAPQ--
MUL_1063|M.ulcerans_Agy99           RAIGSYGDFVNFYSCDISLKINGLQPGGPVRTVRLFSQPT-GRCAPQ--
MLBr_02590|M.leprae_Br4923          RTIGSYGDFVNFYSCDITLKINGLQPGGPVRTVRLFQQPT-GRCTPQ--
Rv0170|M.tuberculosis_H37Rv         RANGTYGDFQNFYLCDLQIKWNGFQAGGPVRTVKLFSQPT-GRCTPQ--
MAB_4152c|M.abscessus_ATCC_199      -ALGAYGSFFNIYYCSIRIKVNGPVGTDWLIPFGGPPDPSKGRCAFKNE
                                     : * **.* *:* *.: :* **    . : ..    :*: ***: :