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M. thermoresistible (build 8) TH_3050 (-)

annotation: Methyltransferase type 12
coordinates: 154729 - 155463
length: 245

aa seq not available

Operon Prediction Model: Genebank

Paralogs
speciesidgenee-valueidentity (len)annotation
M. thermoresistible (build 8)TH_3050--100% (245)Methyltransferase type 12
M. thermoresistible (build 8)TH_2937-2e-0835.92% (103) PUTATIVE Methyltransferase type 11
M. thermoresistible (build 8)TH_1988-2e-0736.11% (108) methyltransferase type 11

Closest Orthologs (e-value cutoff: 1e-4)
speciesidgenee-valueidentity (len)annotation
M. bovis AF2122 / 97Mb0573ubiE9e-1227.35% (245) ubiquinone/menaquinone biosynthesis methyltransferase
M. gilvum PYR-GCKMflv_1845-2e-8770.56% (231) methyltransferase type 11
M. tuberculosis H37RvRv0558ubiE9e-1227.35% (245) ubiquinone/menaquinone biosynthesis methyltransferase
M. leprae Br4923MLBr_02273ubiE8e-1128.89% (225) ubiquinone/menaquinone biosynthesis methyltransferase
M. abscessus ATCC 19977MAB_3930c-3e-0927.93% (179) ubiquinone/menaquinone biosynthesis methlytransferase UbiE
M. marinum MMMAR_0008-2e-1141.82% (110) hypothetical protein MMAR_0008
M. avium 104MAV_3889-4e-8065.94% (229) methyltransferase, UbiE/COQ5 family protein
M. smegmatis MC2 155MSMEG_1115ubiE1e-0927.12% (177) ubiquinone/menaquinone biosynthesis methyltransferase
M. ulcerans Agy99MUL_0660ubiE5e-1027.83% (230) ubiquinone/menaquinone biosynthesis methyltransferase
M. vanbaalenii PYR-1Mvan_4887-2e-8970.13% (231) methyltransferase type 11

CLUSTAL 2.0.9 multiple sequence alignment


Mflv_1845|M.gilvum_PYR-GCK          ---------------MATYDVPDAFDAGADAYDGLVGANPGYHKHLRLSA
Mvan_4887|M.vanbaalenii_PYR-1       -------------MTARNYDVPDAFDAGAPAYDGLVGANPGYHAHLRLSA
TH_3050|M.thermoresistible__bu      --------VTGRRRHLDRAAVPAAFDAGAASYDRLVAANPGYHEHLRLSA
MAV_3889|M.avium_104                --------MRAGDTRPAPGNLAAAFDAGAATYDRLVGASPGYHAQLLLSA
Mb0573|M.bovis_AF2122/97            --------MSRAALDKDPRDVASMFDGVARKYDLTNTVLSLGQDRYWRRA
Rv0558|M.tuberculosis_H37Rv         --------MSRAALDKDPRDVASMFDGVARKYDLTNTVLSLGQDRYWRRA
MUL_0660|M.ulcerans_Agy99           --------MSRAALDKDPRDVASMFDGVARRYDLTNTVLSLGQDRYWRRA
MLBr_02273|M.leprae_Br4923          MPPGSVDVVSRAALDKDPRDVVAMFDDVAHRYDLTNTVLSLGQDRYWRRA
MAB_3930c|M.abscessus_ATCC_199      --------MNRATLEKDPHEVASMFDAVARRYDITNTVLSFGRDRFWRRA
MSMEG_1115|M.smegmatis_MC2_155      --------MSRASLEKNPHDVASMFDAVAKRYDLTNTVLSLGQDRFWRRE
MMAR_0008|M.marinum_M               ------------MDVNRPDYVLGHSDYELGRLGRQAMLLDATTREYLATA
                                                        :    *      .           .     

Mflv_1845|M.gilvum_PYR-GCK          RRMGLP---DGGRGLVLLDIGCGTG-ASTAALLRAAPHAEIVAVDGSAGM
Mvan_4887|M.vanbaalenii_PYR-1       RRMRLP---DQGRGLRLLDIGCGTG-ASTAALLSAAPLADIVAVDGSAGM
TH_3050|M.thermoresistible__bu      HRMGLPGCAARXRGLRILDAGCGTG-ASTAALLTYAPDAEIVAVDASAGM
MAV_3889|M.avium_104                RRMRIP---HDGKGLRLLDAGCGTG-ASTAALLAVAPAADIVAVDASRGM
Mb0573|M.bovis_AF2122/97            TRSALR----IGPGQKVLDLAAGTA-VSTVELTKSG--AWCVAADFSVGM
Rv0558|M.tuberculosis_H37Rv         TRSALR----IGPGQKVLDLAAGTA-VSTVELTKSG--AWCVAADFSVGM
MUL_0660|M.ulcerans_Agy99           TRSALR----IGPGDKVLDLAAGTA-VSSVELAKSG--AWCVAADFSVGM
MLBr_02273|M.leprae_Br4923          TRSALR----IGPGQKVLDLAAGTA-VSTAELSKSG--AWCVAADFSVRM
MAB_3930c|M.abscessus_ATCC_199      TREALR----LKPGDKVLDIAAGTA-VSTAELTQSG--AWCVAADFSVGM
MSMEG_1115|M.smegmatis_MC2_155      TKSALR----IGPADKVLDLAAGTA-VSTVELAKSG--AWCVAADFSVGM
MMAR_0008|M.marinum_M               G---------LEPGMRVLDVGSGPGDVAFLASELTMPGGEVVGTDRAAGA
                                                 .  :** ..*.. .:          .  *..* :   

Mflv_1845|M.gilvum_PYR-GCK          LAQARAKRWPPNV-RFVHSRVEDLAVNGVTGPFDGILAAYLIRNVADRDG
Mvan_4887|M.vanbaalenii_PYR-1       LEQARAKTWPPSV-TFVHSRAETLAAAGVTGPFDGILAAYLIRNVEDPDS
TH_3050|M.thermoresistible__bu      LAAAAAKPWPATV-RFVHSRVEDLAGAGVGGPFDAVFAAYLLRNLPDPDT
MAV_3889|M.avium_104                LEVALAKRWPASV-RFVHAPVQRLAEHGISGPFDGVLAAYLIRNVADRDE
Mb0573|M.bovis_AF2122/97            LAAGAARKVPK-----VAGDATRLPFG--DDVFDAVTISFGLRNVANQQA
Rv0558|M.tuberculosis_H37Rv         LAAGAARKVPK-----VAGDATRLPFG--DDVFDAVTISFGLRNVANQQA
MUL_0660|M.ulcerans_Agy99           LAAGHERRVCK-----VAGDATRLPFA--DDVFDAVTISFGLRNVVDFSA
MLBr_02273|M.leprae_Br4923          LATGGARKVPK-----VAADATQLPFS--DGVFDAVTISFGLRNIADYQA
MAB_3930c|M.abscessus_ATCC_199      LKAGARRDVPK-----VAGDATRLPFA--DHSFDAVTISFGLRNVVDHVE
MSMEG_1115|M.smegmatis_MC2_155      LAAGASRQVPK-----VAGDATRLPFA--DEVFDAVTISFGLRNVVDHKA
MMAR_0008|M.marinum_M               VSAASAAAAARGLSETVRFRLGDPADSSFERPFDAIVGRYVLTFQADPAA
                                    :  .            *       .       **.:   : :    :   

Mflv_1845|M.gilvum_PYR-GCK          VLQELRALLRPGGVFAAHE--YSVRDSRTATALWNLVSSAVIIPAGRLRS
Mvan_4887|M.vanbaalenii_PYR-1       VLGSLRSLLRPGGVLAVHE--YSVRDSRLATAVWNLVSTAIIIPAGRLRS
TH_3050|M.thermoresistible__bu      QLTAFRDLLRPGGILAVHE--YSVRDSAVATAVWNVVCGAVVIPLGRLRT
MAV_3889|M.avium_104                QLRRFRTLLRPGATLAVHE--YSVRDSAAATLAWHALCWGIIIPAGWWRS
Mb0573|M.bovis_AF2122/97            ALREMARVTRPGGRLLVCE--FSTPTNALFATAYKEYLMRALPRVARAVS
Rv0558|M.tuberculosis_H37Rv         ALREMARVTRPGGRLLVCE--FSTPTNALFATAYKEYLMRALPRVARAVS
MUL_0660|M.ulcerans_Agy99           ALREMARVTRPGGRLVVCE--FSTPVSALFATVYKEYLMRALPRVARAVS
MLBr_02273|M.leprae_Br4923          ALREMARVTRPGGQLVVCE--FSTPTNALVANVYTEYLMRALPQVARLVS
MAB_3930c|M.abscessus_ATCC_199      GLREMARVTKPGGRLAVCE--FSTPVNRPFRTLYMEYLMKTLPEVARAVS
MSMEG_1115|M.smegmatis_MC2_155      GLREMARVTKPGGRLVVCE--FSTPTNRLFSTVYKEYLMKALPAMATAVS
MMAR_0008|M.marinum_M               MLHRLSQHLVPGGIVAFHEPDWSAVRSSPPAPTHDRCCHWIREALDRTHT
                                     *  :     **. .   *  :*.  .                      :

Mflv_1845|M.gilvum_PYR-GCK          --GDAELYRYLKRSVNEFDGAAEFRNRLQRNGFVDVTSHTMSGWQHDIVH
Mvan_4887|M.vanbaalenii_PYR-1       --GDAGLYRYLRRSVNNFDGAAQFRDRLRRNGFVDVHSESMPGWQHNIVH
TH_3050|M.thermoresistible__bu      --GDAALYRYLRRSVNTFDGAERFRNRLRACGFTDVRSATMPGWQRDIVH
MAV_3889|M.avium_104                --GDTALYRYLWRSVLAFDGATRFRARLADAGFTAVHSETMPGWEAGIVH
Mb0573|M.bovis_AF2122/97            --SNPEAYEYLAESIRAWPDQAVLAHQISRAGWSGVRWRNLTG---GIVA
Rv0558|M.tuberculosis_H37Rv         --SNPEAYEYLAESIRAWPDQAVLAHQISRAGWSGVRWRNLTG---GIVA
MUL_0660|M.ulcerans_Agy99           --SNPEAYVYLAESIRAWPDQAALAQQMSRAGWSAVRWRNLTG---GIVA
MLBr_02273|M.leprae_Br4923          --SNPDAYIYLAESIRAWPDQVTLACQLSRTGWASPRWRNLTG---GIVA
MAB_3930c|M.abscessus_ATCC_199      --SNPDAYVYLAESIRAWPDQEALAHQIASAGWSNVRWRNLTG---GIVA
MSMEG_1115|M.smegmatis_MC2_155      --SNPEAYVYLAESIRAWPTQAELARQIGEAGWSDVRWRNLTG---GIVA
MMAR_0008|M.marinum_M               SWDMADRLHNAFTGAGLPAPTLTMRTFIGAGRAAAVWLQALADLVETLLP
                                      . .        .         :   :            :..    :: 

Mflv_1845|M.gilvum_PYR-GCK          TFLGRTPQ-----------------------------------------
Mvan_4887|M.vanbaalenii_PYR-1       TFLGRAPQ-----------------------------------------
TH_3050|M.thermoresistible__bu      TFLARRPG-----------------------------------------
MAV_3889|M.avium_104                TFLADAPS-----------------------------------------
Mb0573|M.bovis_AF2122/97            LHAGYKPGKQTPQ------------------------------------
Rv0558|M.tuberculosis_H37Rv         LHAGYKPGKQTPQ------------------------------------
MUL_0660|M.ulcerans_Agy99           LHAGYKP---QPV------------------------------------
MLBr_02273|M.leprae_Br4923          LHAADKPVR----------------------------------------
MAB_3930c|M.abscessus_ATCC_199      LHIATL-------------------------------------------
MSMEG_1115|M.smegmatis_MC2_155      LHAATKPA-----------------------------------------
MMAR_0008|M.marinum_M               TIQAQGVATATEVGIETLTQRLLEEVSDLGATVIGRSEVGAWTRTPRSG
                                       .