For questions or suggestions e-mail us at: ioerger@cs.tamu.edu
MSRAALDKDPRDVASMFDGVARKYDLTNTVLSLGQDRYWRRATRSALRIGPGQKVLDLAAGTAVSTVELT KSGAWCVAADFSVGMLAAGAARKVPKVAGDATRLPFGDDVFDAVTISFGLRNVANQQAALREMARVTRPG GRLLVCEFSTPTNALFATAYKEYLMRALPRVARAVSSNPEAYEYLAESIRAWPDQAVLAHQISRAGWSGV RWRNLTGGIVALHAGYKPGKQTPQ
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. tuberculosis H37Rv | Rv0558 | ubiE | - | 100% (234) | ubiquinone/menaquinone biosynthesis methyltransferase |
| M. tuberculosis H37Rv | Rv1405c | - | 2e-12 | 35.14% (111) | putative methyltransferase |
| M. tuberculosis H37Rv | Rv1403c | - | 2e-07 | 32.65% (98) | putative methyltransferase |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb0573 | ubiE | 1e-133 | 100.00% (234) | ubiquinone/menaquinone biosynthesis methyltransferase |
| M. gilvum PYR-GCK | Mflv_5258 | ubiE | 1e-104 | 80.26% (228) | ubiquinone/menaquinone biosynthesis methyltransferase |
| M. leprae Br4923 | MLBr_02273 | ubiE | 1e-107 | 83.33% (228) | ubiquinone/menaquinone biosynthesis methyltransferase |
| M. abscessus ATCC 19977 | MAB_3930c | - | 1e-99 | 78.48% (223) | ubiquinone/menaquinone biosynthesis methlytransferase UbiE |
| M. marinum M | MMAR_0907 | ubiE | 1e-116 | 90.79% (228) | ubiquinone/menaquinone methlytransferase, MenH |
| M. avium 104 | MAV_4584 | ubiE | 1e-115 | 89.04% (228) | ubiquinone/menaquinone biosynthesis methyltransferase |
| M. smegmatis MC2 155 | MSMEG_1115 | ubiE | 1e-106 | 82.02% (228) | ubiquinone/menaquinone biosynthesis methyltransferase |
| M. thermoresistible (build 8) | TH_3050 | - | 9e-12 | 27.35% (245) | PUTATIVE Methyltransferase type 12 |
| M. ulcerans Agy99 | MUL_0660 | ubiE | 1e-115 | 89.91% (228) | ubiquinone/menaquinone biosynthesis methyltransferase |
| M. vanbaalenii PYR-1 | Mvan_0983 | ubiE | 1e-105 | 82.38% (227) | ubiquinone/menaquinone biosynthesis methyltransferase |
CLUSTAL 2.0.9 multiple sequence alignment
Mflv_5258|M.gilvum_PYR-GCK -----------------MNRASLEKNPHEVASMFDGVARRYDLTNTVLSL
Mvan_0983|M.vanbaalenii_PYR-1 -----------------MNRASLEKDPHEVASMFDGVARRYDLTNTVLSL
MSMEG_1115|M.smegmatis_MC2_155 -----------------MSRASLEKNPHDVASMFDAVAKRYDLTNTVLSL
MAB_3930c|M.abscessus_ATCC_199 -----------------MNRATLEKDPHEVASMFDAVARRYDITNTVLSF
Rv0558|M.tuberculosis_H37Rv -----------------MSRAALDKDPRDVASMFDGVARKYDLTNTVLSL
Mb0573|M.bovis_AF2122/97 -----------------MSRAALDKDPRDVASMFDGVARKYDLTNTVLSL
MMAR_0907|M.marinum_M -----------------MSRAALDKDPRDVASMFDGVARRYDLTNTVLSL
MUL_0660|M.ulcerans_Agy99 -----------------MSRAALDKDPRDVASMFDGVARRYDLTNTVLSL
MAV_4584|M.avium_104 MQRWRRRGIPAPGSVKRVSRAELDKNPRDVASMFDGVARRYDLTNTVLSL
MLBr_02273|M.leprae_Br4923 ---------MPPGSVDVVSRAALDKDPRDVVAMFDDVAHRYDLTNTVLSL
TH_3050|M.thermoresistible__bu -----------------VTGRRRHLDRAAVPAAFDAGAASYDRLVAANPG
:. . : * : ** * ** :. .
Mflv_5258|M.gilvum_PYR-GCK GQDRFWRRATREALQLSPAD----KVLDLAAGTAVSTVELASSG--AWCV
Mvan_0983|M.vanbaalenii_PYR-1 GQDRFWRRATREALQLSPSD----KVLDLAAGTAVSTVELAGSG--AWCV
MSMEG_1115|M.smegmatis_MC2_155 GQDRFWRRETKSALRIGPAD----KVLDLAAGTAVSTVELAKSG--AWCV
MAB_3930c|M.abscessus_ATCC_199 GRDRFWRRATREALRLKPGD----KVLDIAAGTAVSTAELTQSG--AWCV
Rv0558|M.tuberculosis_H37Rv GQDRYWRRATRSALRIGPGQ----KVLDLAAGTAVSTVELTKSG--AWCV
Mb0573|M.bovis_AF2122/97 GQDRYWRRATRSALRIGPGQ----KVLDLAAGTAVSTVELTKSG--AWCV
MMAR_0907|M.marinum_M GQDRYWRRATRSALRIGPGD----KVLDLAAGTAVSTVELAKSG--AWCV
MUL_0660|M.ulcerans_Agy99 GQDRYWRRATRSALRIGPGD----KVLDLAAGTAVSSVELAKSG--AWCV
MAV_4584|M.avium_104 GQDRYWRKATRSALGIGPGQ----KVLDLAAGTAVSTVELNKSG--AWCV
MLBr_02273|M.leprae_Br4923 GQDRYWRRATRSALRIGPGQ----KVLDLAAGTAVSTAELSKSG--AWCV
TH_3050|M.thermoresistible__bu YHEHLRLSAHRMGLPGCAARXRGLRILDAGCGTGASTAALLTYAPDAEIV
::: : .* .. ::** ..**..*:. * . * *
Mflv_5258|M.gilvum_PYR-GCK AADFSVGMLAAGASR----RVPKVAGDATRLPFD--DGVFDAVTISFGLR
Mvan_0983|M.vanbaalenii_PYR-1 AADFSVGMLAAGAAR----DVPKVAGDATRLPFA--DGVFDAVTISFGLR
MSMEG_1115|M.smegmatis_MC2_155 AADFSVGMLAAGASR----QVPKVAGDATRLPFA--DEVFDAVTISFGLR
MAB_3930c|M.abscessus_ATCC_199 AADFSVGMLKAGARR----DVPKVAGDATRLPFA--DHSFDAVTISFGLR
Rv0558|M.tuberculosis_H37Rv AADFSVGMLAAGAAR----KVPKVAGDATRLPFG--DDVFDAVTISFGLR
Mb0573|M.bovis_AF2122/97 AADFSVGMLAAGAAR----KVPKVAGDATRLPFG--DDVFDAVTISFGLR
MMAR_0907|M.marinum_M AADFSVGMLAAGHER----KVCKVAGDATRLPFA--DDVFDAVTISFGLR
MUL_0660|M.ulcerans_Agy99 AADFSVGMLAAGHER----RVCKVAGDATRLPFA--DDVFDAVTISFGLR
MAV_4584|M.avium_104 AADFSVGMLAAGAAR----RVPKVAGDATRLPFA--DDVFDAVTISFGLR
MLBr_02273|M.leprae_Br4923 AADFSVRMLATGGAR----KVPKVAADATQLPFS--DGVFDAVTISFGLR
TH_3050|M.thermoresistible__bu AVDASAGMLAAAAAKPWPATVRFVHSRVEDLAGAGVGGPFDAVFAAYLLR
*.* *. ** :. : * * . . *. . **** :: **
Mflv_5258|M.gilvum_PYR-GCK NVVDFSAGLREMARVTRPGGRLVVCEFSTPTNGLFSTVYKEYLMKALPAM
Mvan_0983|M.vanbaalenii_PYR-1 NVVDHSAGLREMARVTRPGGRLVVCEFSTPTNKLFATVYKEYLMRALPAM
MSMEG_1115|M.smegmatis_MC2_155 NVVDHKAGLREMARVTKPGGRLVVCEFSTPTNRLFSTVYKEYLMKALPAM
MAB_3930c|M.abscessus_ATCC_199 NVVDHVEGLREMARVTKPGGRLAVCEFSTPVNRPFRTLYMEYLMKTLPEV
Rv0558|M.tuberculosis_H37Rv NVANQQAALREMARVTRPGGRLLVCEFSTPTNALFATAYKEYLMRALPRV
Mb0573|M.bovis_AF2122/97 NVANQQAALREMARVTRPGGRLLVCEFSTPTNALFATAYKEYLMRALPRV
MMAR_0907|M.marinum_M NVVDFSAALREMARVTRPGGRLVVCEFSTPVSALFATVYKEYLMRALPRV
MUL_0660|M.ulcerans_Agy99 NVVDFSAALREMARVTRPGGRLVVCEFSTPVSALFATVYKEYLMRALPRV
MAV_4584|M.avium_104 NVVDTQAALREMARVTRPGGRLVVCEFSTPSNALFATVYKEYLMRALPRV
MLBr_02273|M.leprae_Br4923 NIADYQAALREMARVTRPGGQLVVCEFSTPTNALVANVYTEYLMRALPQV
TH_3050|M.thermoresistible__bu NLPDPDTQLTAFRDLLRPGGILAVHEYSVRDSAVATAVWNVVCGAVVIPL
*: : * : : :*** * * *:*. . : .: :
Mflv_5258|M.gilvum_PYR-GCK ATAVSSNPDAYVYLAESIRAWPDQRALARRIEAAGWSDVRWRNLTG---G
Mvan_0983|M.vanbaalenii_PYR-1 ASAVSSNPDAYVYLAESIRAWPDQAELAARIEAAGWSDVRWRNLTG---G
MSMEG_1115|M.smegmatis_MC2_155 ATAVSSNPEAYVYLAESIRAWPTQAELARQIGEAGWSDVRWRNLTG---G
MAB_3930c|M.abscessus_ATCC_199 ARAVSSNPDAYVYLAESIRAWPDQEALAHQIASAGWSNVRWRNLTG---G
Rv0558|M.tuberculosis_H37Rv ARAVSSNPEAYEYLAESIRAWPDQAVLAHQISRAGWSGVRWRNLTG---G
Mb0573|M.bovis_AF2122/97 ARAVSSNPEAYEYLAESIRAWPDQAVLAHQISRAGWSGVRWRNLTG---G
MMAR_0907|M.marinum_M ARAVSSNPEAYVYLAESIRAWPDQAALAQQMSRAGWSAVRWRNLTG---G
MUL_0660|M.ulcerans_Agy99 ARAVSSNPEAYVYLAESIRAWPDQAALAQQMSRAGWSAVRWRNLTG---G
MAV_4584|M.avium_104 ARAVSSNPDAYVYLAESIRAWPDQAALADQIAGAGWAGVRWRNLTG---G
MLBr_02273|M.leprae_Br4923 ARLVSSNPDAYIYLAESIRAWPDQVTLACQLSRTGWASPRWRNLTG---G
TH_3050|M.thermoresistible__bu GRLRTGDAALYRYLRRSVNTFDGAERFRNRLRACGFTDVRSATMPGWQRD
. :.:. * ** .*:.:: : :: *:: * .:.* .
Mflv_5258|M.gilvum_PYR-GCK IVALHAATKP------
Mvan_0983|M.vanbaalenii_PYR-1 IVALHAATKA------
MSMEG_1115|M.smegmatis_MC2_155 IVALHAATKPA-----
MAB_3930c|M.abscessus_ATCC_199 IVALHIATL-------
Rv0558|M.tuberculosis_H37Rv IVALHAGYKPGKQTPQ
Mb0573|M.bovis_AF2122/97 IVALHAGYKPGKQTPQ
MMAR_0907|M.marinum_M IVALHAGYKP---QPV
MUL_0660|M.ulcerans_Agy99 IVALHAGYKP---QPV
MAV_4584|M.avium_104 IVALHAAHRP----PR
MLBr_02273|M.leprae_Br4923 IVALHAADKP----VR
TH_3050|M.thermoresistible__bu IVHTFLARRPG-----
** . .