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ATYDVPDAFDAGADAYDGLVGANPGYHKHLRLSARRMGLPDGGRGLVLLDIGCGTGASTAALLRAAPHAE IVAVDGSAGMLAQARAKRWPPNVRFVHSRVEDLAVNGVTGPFDGILAAYLIRNVADRDGVLQELRALLRP GGVFAAHEYSVRDSRTATALWNLVSSAVIIPAGRLRSGDAELYRYLKRSVNEFDGAAEFRNRLQRNGFVD VTSHTMSGWQHDIVHTFLGRTPQ*
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. gilvum PYR-GCK | Mflv_1845 | - | - | 100% (234) | methyltransferase type 11 |
| M. gilvum PYR-GCK | Mflv_5258 | ubiE | 5e-10 | 26.90% (171) | ubiquinone/menaquinone biosynthesis methyltransferase |
| M. gilvum PYR-GCK | Mflv_0738 | - | 1e-07 | 34.91% (106) | methyltransferase type 11 |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb0573 | ubiE | 1e-12 | 27.60% (221) | ubiquinone/menaquinone biosynthesis methyltransferase |
| M. tuberculosis H37Rv | Rv0558 | ubiE | 1e-12 | 27.60% (221) | ubiquinone/menaquinone biosynthesis methyltransferase |
| M. leprae Br4923 | MLBr_02273 | ubiE | 1e-12 | 27.40% (219) | ubiquinone/menaquinone biosynthesis methyltransferase |
| M. abscessus ATCC 19977 | MAB_3930c | - | 4e-10 | 27.52% (218) | ubiquinone/menaquinone biosynthesis methlytransferase UbiE |
| M. marinum M | MMAR_0907 | ubiE | 5e-11 | 27.20% (239) | ubiquinone/menaquinone methlytransferase, MenH |
| M. avium 104 | MAV_3889 | - | 4e-77 | 64.89% (225) | methyltransferase, UbiE/COQ5 family protein |
| M. smegmatis MC2 155 | MSMEG_1115 | ubiE | 2e-12 | 28.05% (221) | ubiquinone/menaquinone biosynthesis methyltransferase |
| M. thermoresistible (build 8) | TH_3050 | - | 1e-87 | 70.56% (231) | PUTATIVE Methyltransferase type 12 |
| M. ulcerans Agy99 | MUL_0660 | ubiE | 4e-11 | 27.20% (239) | ubiquinone/menaquinone biosynthesis methyltransferase |
| M. vanbaalenii PYR-1 | Mvan_4887 | - | 1e-107 | 82.68% (231) | methyltransferase type 11 |
CLUSTAL 2.0.9 multiple sequence alignment
MAB_3930c|M.abscessus_ATCC_199 --------MNRATLEKDPHEVASMFDAVARRYDITNTVLSFGRDRFWRRA
MSMEG_1115|M.smegmatis_MC2_155 --------MSRASLEKNPHDVASMFDAVAKRYDLTNTVLSLGQDRFWRRE
Mb0573|M.bovis_AF2122/97 --------MSRAALDKDPRDVASMFDGVARKYDLTNTVLSLGQDRYWRRA
Rv0558|M.tuberculosis_H37Rv --------MSRAALDKDPRDVASMFDGVARKYDLTNTVLSLGQDRYWRRA
MMAR_0907|M.marinum_M --------MSRAALDKDPRDVASMFDGVARRYDLTNTVLSLGQDRYWRRA
MUL_0660|M.ulcerans_Agy99 --------MSRAALDKDPRDVASMFDGVARRYDLTNTVLSLGQDRYWRRA
MLBr_02273|M.leprae_Br4923 MPPGSVDVVSRAALDKDPRDVVAMFDDVAHRYDLTNTVLSLGQDRYWRRA
Mflv_1845|M.gilvum_PYR-GCK ---------------MATYDVPDAFDAGADAYDGLVGANPGYHKHLRLSA
Mvan_4887|M.vanbaalenii_PYR-1 -------------MTARNYDVPDAFDAGAPAYDGLVGANPGYHAHLRLSA
TH_3050|M.thermoresistible__bu --------VTGRRRHLDRAAVPAAFDAGAASYDRLVAANPGYHEHLRLSA
MAV_3889|M.avium_104 --------MRAGDTRPAPGNLAAAFDAGAATYDRLVGASPGYHAQLLLSA
: ** * ** . . : :
MAB_3930c|M.abscessus_ATCC_199 TREALR----LKPGDKVLDIAAGTAVSTAELTQSG--AWCVAADFSVGML
MSMEG_1115|M.smegmatis_MC2_155 TKSALR----IGPADKVLDLAAGTAVSTVELAKSG--AWCVAADFSVGML
Mb0573|M.bovis_AF2122/97 TRSALR----IGPGQKVLDLAAGTAVSTVELTKSG--AWCVAADFSVGML
Rv0558|M.tuberculosis_H37Rv TRSALR----IGPGQKVLDLAAGTAVSTVELTKSG--AWCVAADFSVGML
MMAR_0907|M.marinum_M TRSALR----IGPGDKVLDLAAGTAVSTVELAKSG--AWCVAADFSVGML
MUL_0660|M.ulcerans_Agy99 TRSALR----IGPGDKVLDLAAGTAVSSVELAKSG--AWCVAADFSVGML
MLBr_02273|M.leprae_Br4923 TRSALR----IGPGQKVLDLAAGTAVSTAELSKSG--AWCVAADFSVRML
Mflv_1845|M.gilvum_PYR-GCK RRMGLP---DGGRGLVLLDIGCGTGASTAALLRAAPHAEIVAVDGSAGML
Mvan_4887|M.vanbaalenii_PYR-1 RRMRLP---DQGRGLRLLDIGCGTGASTAALLSAAPLADIVAVDGSAGML
TH_3050|M.thermoresistible__bu HRMGLPGCAARXRGLRILDAGCGTGASTAALLTYAPDAEIVAVDASAGML
MAV_3889|M.avium_104 RRMRIP---HDGKGLRLLDAGCGTGASTAALLAVAPAADIVAVDASRGML
: : . :** ..**..*:. * . * **.* * **
MAB_3930c|M.abscessus_ATCC_199 KAGARRDVPK----VAGDATRLPFA--DHSFDAVTISFGLRNVVDHVEGL
MSMEG_1115|M.smegmatis_MC2_155 AAGASRQVPK----VAGDATRLPFA--DEVFDAVTISFGLRNVVDHKAGL
Mb0573|M.bovis_AF2122/97 AAGAARKVPK----VAGDATRLPFG--DDVFDAVTISFGLRNVANQQAAL
Rv0558|M.tuberculosis_H37Rv AAGAARKVPK----VAGDATRLPFG--DDVFDAVTISFGLRNVANQQAAL
MMAR_0907|M.marinum_M AAGHERKVCK----VAGDATRLPFA--DDVFDAVTISFGLRNVVDFSAAL
MUL_0660|M.ulcerans_Agy99 AAGHERRVCK----VAGDATRLPFA--DDVFDAVTISFGLRNVVDFSAAL
MLBr_02273|M.leprae_Br4923 ATGGARKVPK----VAADATQLPFS--DGVFDAVTISFGLRNIADYQAAL
Mflv_1845|M.gilvum_PYR-GCK AQARAKRWPPNVRFVHSRVEDLAVNGVTGPFDGILAAYLIRNVADRDGVL
Mvan_4887|M.vanbaalenii_PYR-1 EQARAKTWPPSVTFVHSRAETLAAAGVTGPFDGILAAYLIRNVEDPDSVL
TH_3050|M.thermoresistible__bu AAAAAKPWPATVRFVHSRVEDLAGAGVGGPFDAVFAAYLLRNLPDPDTQL
MAV_3889|M.avium_104 EVALAKRWPASVRFVHAPVQRLAEHGISGPFDGVLAAYLIRNVADRDEQL
. : * . . *. **.: :: :**: : *
MAB_3930c|M.abscessus_ATCC_199 REMARVTKPGGRLAVCEFSTPVNRPFRTLYMEYLMKTLPEVARAVSSNPD
MSMEG_1115|M.smegmatis_MC2_155 REMARVTKPGGRLVVCEFSTPTNRLFSTVYKEYLMKALPAMATAVSSNPE
Mb0573|M.bovis_AF2122/97 REMARVTRPGGRLLVCEFSTPTNALFATAYKEYLMRALPRVARAVSSNPE
Rv0558|M.tuberculosis_H37Rv REMARVTRPGGRLLVCEFSTPTNALFATAYKEYLMRALPRVARAVSSNPE
MMAR_0907|M.marinum_M REMARVTRPGGRLVVCEFSTPVSALFATVYKEYLMRALPRVARAVSSNPE
MUL_0660|M.ulcerans_Agy99 REMARVTRPGGRLVVCEFSTPVSALFATVYKEYLMRALPRVARAVSSNPE
MLBr_02273|M.leprae_Br4923 REMARVTRPGGQLVVCEFSTPTNALVANVYTEYLMRALPQVARLVSSNPD
Mflv_1845|M.gilvum_PYR-GCK QELRALLRPGGVFAAHEYSVRDSRTATALWNLVSSAVIIPAGRLRSGDAE
Mvan_4887|M.vanbaalenii_PYR-1 GSLRSLLRPGGVLAVHEYSVRDSRLATAVWNLVSTAIIIPAGRLRSGDAG
TH_3050|M.thermoresistible__bu TAFRDLLRPGGILAVHEYSVRDSAVATAVWNVVCGAVVIPLGRLRTGDAA
MAV_3889|M.avium_104 RRFRTLLRPGATLAVHEYSVRDSAAATLAWHALCWGIIIPAGWWRSGDTA
: : :**. : . *:*. . : : . :.:.
MAB_3930c|M.abscessus_ATCC_199 AYVYLAESIRAWPDQEALAHQIASAGWSNVRWRNLTG---GIVALHIATL
MSMEG_1115|M.smegmatis_MC2_155 AYVYLAESIRAWPTQAELARQIGEAGWSDVRWRNLTG---GIVALHAATK
Mb0573|M.bovis_AF2122/97 AYEYLAESIRAWPDQAVLAHQISRAGWSGVRWRNLTG---GIVALHAGYK
Rv0558|M.tuberculosis_H37Rv AYEYLAESIRAWPDQAVLAHQISRAGWSGVRWRNLTG---GIVALHAGYK
MMAR_0907|M.marinum_M AYVYLAESIRAWPDQAALAQQMSRAGWSAVRWRNLTG---GIVALHAGYK
MUL_0660|M.ulcerans_Agy99 AYVYLAESIRAWPDQAALAQQMSRAGWSAVRWRNLTG---GIVALHAGYK
MLBr_02273|M.leprae_Br4923 AYIYLAESIRAWPDQVTLACQLSRTGWASPRWRNLTG---GIVALHAADK
Mflv_1845|M.gilvum_PYR-GCK LYRYLKRSVNEFDGAAEFRNRLQRNGFVDVTSHTMSGWQHDIVHTFLGRT
Mvan_4887|M.vanbaalenii_PYR-1 LYRYLRRSVNNFDGAAQFRDRLRRNGFVDVHSESMPGWQHNIVHTFLGRA
TH_3050|M.thermoresistible__bu LYRYLRRSVNTFDGAERFRNRLRACGFTDVRSATMPGWQRDIVHTFLARR
MAV_3889|M.avium_104 LYRYLWRSVLAFDGATRFRARLADAGFTAVHSETMPGWEAGIVHTFLADA
* ** .*: : : :: *: .:.* .** . .
MAB_3930c|M.abscessus_ATCC_199 -------
MSMEG_1115|M.smegmatis_MC2_155 PA-----
Mb0573|M.bovis_AF2122/97 PGKQTPQ
Rv0558|M.tuberculosis_H37Rv PGKQTPQ
MMAR_0907|M.marinum_M P---QPV
MUL_0660|M.ulcerans_Agy99 P---QPV
MLBr_02273|M.leprae_Br4923 PVR----
Mflv_1845|M.gilvum_PYR-GCK PQ-----
Mvan_4887|M.vanbaalenii_PYR-1 PQ-----
TH_3050|M.thermoresistible__bu PG-----
MAV_3889|M.avium_104 PS-----