For questions or suggestions e-mail us at: ioerger@cs.tamu.edu
aa seq not available
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. thermoresistible (build 8) | TH_3021 | - | - | 100% (397) | cytochrome P450 |
| M. thermoresistible (build 8) | TH_4114 | - | e-137 | 58.88% (394) | PUTATIVE cytochrome P450 |
| M. thermoresistible (build 8) | TH_2671 | - | e-130 | 55.75% (391) | PUTATIVE cytochrome P450 monooxygenase |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb0789c | cyp123 | 6e-62 | 35.37% (393) | cytochrome P450 123 |
| M. gilvum PYR-GCK | Mflv_2431 | - | 1e-180 | 75.25% (404) | cytochrome P450 |
| M. tuberculosis H37Rv | Rv1256c | cyp130 | 3e-63 | 36.39% (393) | cytochrome P450 130 CYP130 |
| M. leprae Br4923 | MLBr_02088 | - | 2e-40 | 30.17% (401) | putative cytochrome p450 |
| M. abscessus ATCC 19977 | MAB_1406c | - | 5e-66 | 36.84% (418) | cytochrome P450 |
| M. marinum M | MMAR_4753 | cyp189A7 | 1e-174 | 71.54% (397) | cytochrome P450 189A7 Cyp189A7 |
| M. avium 104 | MAV_2984 | - | 1e-165 | 68.75% (400) | cytochrome P450 |
| M. smegmatis MC2 155 | MSMEG_4829 | - | 1e-171 | 72.59% (394) | cytochrome P450 |
| M. ulcerans Agy99 | MUL_0324 | cyp189A7 | 1e-172 | 70.78% (397) | cytochrome P450 189A7 Cyp189A7 |
| M. vanbaalenii PYR-1 | Mvan_4221 | - | 1e-175 | 73.71% (388) | cytochrome P450 |
CLUSTAL 2.0.9 multiple sequence alignment
Mflv_2431|M.gilvum_PYR-GCK ------MSYVRLIQREGAVTISAENSDVHDAET-DELYYDTQSVELNMDP
Mvan_4221|M.vanbaalenii_PYR-1 ------------------MTISADDSDVQNADTAAELYYDPYNVDLNMDP
MSMEG_4829|M.smegmatis_MC2_155 ---------------------MAQPS----TSATPDLYYDPYSVQLNMEP
TH_3021|M.thermoresistible__bu ----------------------------VTVSAPNDVHYDPYDVELNADP
MMAR_4753|M.marinum_M ----------------------------MTVTAASDVYFDPYDVELNADP
MUL_0324|M.ulcerans_Agy99 ----------------------------MTVTAASDVYFDPYDVELNADP
MAV_2984|M.avium_104 ----------------------------MTASTDSDVRFDPYDVGLIADP
Rv1256c|M.tuberculosis_H37Rv ------------------------------MTSVMSHEFQLATAETWPNP
MAB_1406c|M.abscessus_ATCC_199 --------------------------MSVDVSHTVAPRYVPGTADNWTNP
Mb0789c|M.bovis_AF2122/97 ---------------------------MTVRVGDPELVLDPYDYDFHEDP
MLBr_02088|M.leprae_Br4923 MRTCVPTRTCVYAFIEYLSHNRPMGTNPPSLVEAQMLLLRLIDPGTRADP
:*
Mflv_2431|M.gilvum_PYR-GCK YAVFARLREEAPLYYN-----AKHDFYALSRYEDVNKAVIDHETFISGRG
Mvan_4221|M.vanbaalenii_PYR-1 HGVFARLREEAPLYYN-----DKHDFYALSRYEDVNKGVIDHQTFISGRG
MSMEG_4829|M.smegmatis_MC2_155 HEVFARIREEAPLYYN-----EQHDFYALSRYHDVNKAVIDHETFISGRG
TH_3021|M.thermoresistible__bu YPMFKRIREEAPLYYN-----PTHDFYALSRFDDVNSAILDHETFSSARG
MMAR_4753|M.marinum_M YPMFRRLREEAPLYYN-----AQHGFYALSRFADVDRAIVDYQTFSSARG
MUL_0324|M.ulcerans_Agy99 YPMFRRLREEAPLYYN-----AQHGFYALSRFADVDRAIVDYQTFSSARG
MAV_2984|M.avium_104 YPMFARLREEAPLYYN-----AEYDFYAVSRYADVSKALVDHETYSSARG
Rv1256c|M.tuberculosis_H37Rv WPMYRALRDHDPVHHVVPPQRPEYDYYVLSRHADVWSAARDHQTFSSAQG
MAB_1406c|M.abscessus_ATCC_199 WPMYAALRDHDPVHHVVPEYTPDQDYYVLTRHADVYEAARDWETFSSARG
Mb0789c|M.bovis_AF2122/97 YPYYRRLRDEAPLYRN-----EERNFWAVSRHHDVLQGFRDSTALSNAYG
MLBr_02088|M.leprae_Br4923 FPVYRALIDYGPMQLPG---MPLTVFSSFSDCDEALRHPLSASDRLKATL
: : : *: : .: :. . ..
Mflv_2431|M.gilvum_PYR-GCK ALLEIIKSGMEIPPG--TLIFEDPPIHNIHRNLLSRVFTPRKVLALEPQI
Mvan_4221|M.vanbaalenii_PYR-1 ALLEIIKSGMEIPPG--TLIFEDPPIHNIHRNLLSRVFTPRKVQALEPQI
MSMEG_4829|M.smegmatis_MC2_155 ALLELIKSGMEIPPG--TLIFEDPPIHNIHRNLLSRMFTPRKVLALEPQI
TH_3021|M.thermoresistible__bu AVLEIIKSGMEIPPG--TLIFEDPPIHNIHRKLLSRMFTPRKIAALEPRI
MMAR_4753|M.marinum_M AILEIIKANIDIPAG--VLVFEDPPVHDVHRKLLSRMFTPRKINDLEPKI
MUL_0324|M.ulcerans_Agy99 AILEFIKANIDIPAG--VLVFEDPPVHDVHRKLLSRMFTPRKINDLEPKI
MAV_2984|M.avium_104 AILELIKANLDIPSG--MLIFEDPPIHDVHRKLLSRMFTPRRIAALEPMI
Rv1256c|M.tuberculosis_H37Rv LTVNYGELEMIGLHDTPPMVMQDPPVHTEFRKLVSRGFTPRQVETVEPTV
MAB_1406c|M.abscessus_ATCC_199 LTVTYGDLEKTGMGDNPPMVMQDPPTHTEFRKLVSRGFTPRQVTAVEPKV
Mb0789c|M.bovis_AF2122/97 VSLDPSSRTSEAYRVMSMLAMDDP-AHLRMRTLVSKGFTPRRIRELEPQV
MLBr_02088|M.leprae_Br4923 AQQAIAAGAEPRPFYASSFMFLDPPDHTRLRKLVSKAFAPKVVQALEGDI
: : ** * *.*:*: *:*: : :* :
Mflv_2431|M.gilvum_PYR-GCK REFTARCLDPVVGTGKFDFVKDLGNQMPMRVIGMLLGIPEEDQRRVTDHG
Mvan_4221|M.vanbaalenii_PYR-1 REFTARCLDPLTGTNRFDFVRDLGAQMPMRVIGMLLGIPEEDQRRVTDHG
MSMEG_4829|M.smegmatis_MC2_155 REFTTRCLDAVAGSDTFDFVNDLGEQMPMRVIGMLLGIPEDRQRAITDHG
TH_3021|M.thermoresistible__bu REFTARCLDPLVGTGRFDFVQDLGEQMPMRVIGMLLGIPEEDQRHVVDHG
MMAR_4753|M.marinum_M REFCARSLDPLIGSGRFDFVADLGAQMPMRVIGMLLGVPEEDQEAARDFA
MUL_0324|M.ulcerans_Agy99 REFCARSLDPLIGSGRFDFVADLGAQMPMRVIGMLLGVPEEDQEAARDFA
MAV_2984|M.avium_104 RDFCAQCLDPLVGTGHFDFVTDLGAQMPMKVISMLLGIPEDDQEYIRDRG
Rv1256c|M.tuberculosis_H37Rv RKFVVERLEKLRANGGGDIVTELFKPLPSMVVAHYLGVPEEDWTQFDGWT
MAB_1406c|M.abscessus_ATCC_199 REFVVQRLERLKERGEGDIVVELFKPLPSMVVAHYLGVPEEDRTQFDAWT
Mb0789c|M.bovis_AF2122/97 LELARIHLDSALQTESFDFVAEFAGKLPMDVISELIGVPDTDRARIRALA
MLBr_02088|M.leprae_Br4923 AALVDSLLDKGAAAGQFDVIADLAFPLAVAVICRLLGVPYEDAPEFGRVS
: *: *.: :: :. *: :*:*
Mflv_2431|M.gilvum_PYR-GCK EATLQSD-----------------SVDLMATGEVFAEFIDYRTEHPSNDI
Mvan_4221|M.vanbaalenii_PYR-1 EATLQSD-----------------SVDLMATGEVFAEFIDHRTEHPSDDI
MSMEG_4829|M.smegmatis_MC2_155 EETLQGT-----------------TVDSLATGEVFAEFIDWRADNPSDDI
TH_3021|M.thermoresistible__bu EATIRTER--------------GGKMSGLATGEVFAEYIDYRAKHPSDDI
MMAR_4753|M.marinum_M TAQLRTEAG----------KPMKASADGMVSGDFFAHYIDWRAEHPSSDI
MUL_0324|M.ulcerans_Agy99 TAQLRTEAG----------KPMKASADGMVSGDFFAHYIDWRAEHPSSDI
MAV_2984|M.avium_104 NAQLRTEAG----------KPMKAAEQGLSVGEQFEAYIDWRAEHPSDDI
Rv1256c|M.tuberculosis_H37Rv QAIVAAN-----AVDG---ATTGALDAVGSMMAYFTGLIERRRTEPADDA
MAB_1406c|M.abscessus_ATCC_199 DGIVAAASGGAIDIEA---MQGEVAQTIGELMMYFTGLIERRRAEPEDDT
Mb0789c|M.bovis_AF2122/97 DAVLHREDG----VAD---VPPPAMAASIELMRYYADLIAEFRRRPANNL
MLBr_02088|M.leprae_Br4923 ALLVQSVDPFITITGEPPEATEERLRAGVWLRDYLEQLVKCRRGTPGEDL
: : * .:
Mflv_2431|M.gilvum_PYR-GCK MTDLLNAEFEDETGTRRKLRREELLMYLTVISTAGSETTTRLIGWAGKTL
Mvan_4221|M.vanbaalenii_PYR-1 MTDLLNAEFEDETGTRRRLRRDELLMYLTVIATAGSETTTRLIGWAGKTL
MSMEG_4829|M.smegmatis_MC2_155 MTDLLNAEFEDETGTVRKLRRDELLLYLTVIATAGSETTTRALGWAGKTL
TH_3021|M.thermoresistible__bu MTELMNAEFEDETGTVRKLGREELLLYLTVIATAGSETTTRLIGWTGKLL
MMAR_4753|M.marinum_M MTELLNAEFEDETGTVRRLRRDELLTYVSVVSGAGNETTTRLIGWAGKVL
MUL_0324|M.ulcerans_Agy99 MTELLNAEFEDETGTVRRLRRDELLTYVSVVSGAGNETTTRLIGWAGKVL
MAV_2984|M.avium_104 MTELLNVEFVDETGTTRRLTREEILVYLNVVAGAGNETTTRLIGWTGKVL
Rv1256c|M.tuberculosis_H37Rv ISHLVAAGVGADGDTAGTLS---ILAFTFTMVTGGNDTVTGMLGGSMPLL
MAB_1406c|M.abscessus_ATCC_199 VSHLVAAGVGADGDISGTLQ---ILGFAFTMVTGGNDTTTGMLGGAIQLL
Mb0789c|M.bovis_AF2122/97 TSALLAAELDGD-----RLSDQEIMAFLFLMVIAGNETTTKLLANAVYWA
MLBr_02088|M.leprae_Br4923 ISRLIELDESGD-----QLTEEEIIATCGLLLVAGHETTVNLIANAVLAM
: *: : * :: : .* :*.. :. :
Mflv_2431|M.gilvum_PYR-GCK ADYPDQRAELAADHSLIPQAIEEILRWEPPALQIARYVTRDVEYYGQTVP
Mvan_4221|M.vanbaalenii_PYR-1 ADYPEQRAQLVADPALIPQAIEEILRWEPPALQIARYVTRDVEYYGQVVP
MSMEG_4829|M.smegmatis_MC2_155 ADHPDQRRDLVENPALIPQAIEELLRWEPPALQIARYVTRDVEYYGKTVP
TH_3021|M.thermoresistible__bu SEHPDQRAELVADRSLLPQAIEEILRFEPPAPHMCRYVTRDVEYYGQTVP
MMAR_4753|M.marinum_M AEHPDQRRALVEDPSLIPQAVEELLRYEAPAPHVARYVTRDLRYYGESVP
MUL_0324|M.ulcerans_Agy99 AEHPDQRRALVEDPSLIPQAVEELLRYEAPAPHVARYVTRDLRYYGQSVP
MAV_2984|M.avium_104 AEHPDQRRDLVENPALIPQAIEELLRYEPPAPHVSRYVTRDVVVHDQTVP
Rv1256c|M.tuberculosis_H37Rv HRRPDQRRLLLDDPEGIPDAVEELLRLTSPVQGLARTTTRDVTIGDTTIP
MAB_1406c|M.abscessus_ATCC_199 HQNPAQRQKLIDDPSLIPGAVEEFLRLTSPVQGLARTATRDVIIGDTTIP
Mb0789c|M.bovis_AF2122/97 AHHPGQLARVFADHSRIPMWVEETLRYDTSSQILARTVAHDLTLYDTTIP
MLBr_02088|M.leprae_Br4923 LRNPSQWKALSSNPQRAPLVVEETLRYDPAIHLIGRVAAKDMTIGQTTLT
* * : : * :** ** .. : * .::*: :.
Mflv_2431|M.gilvum_PYR-GCK AGSAMLMLVGSANRDHRRFPPDGDVFDIHREL-RSHMTFGAGTHFCMGNA
Mvan_4221|M.vanbaalenii_PYR-1 EGSAMLMLVGSANRDHRRFPPNGDVFDIHREL-RSHMTFGAGTHFCMGNA
MSMEG_4829|M.smegmatis_MC2_155 AGSAMLMLVGAANRDHRRFPPNGDVFDIHREQ-FSHMTFGAGTHFCMGNA
TH_3021|M.thermoresistible__bu AGSAMMLLVGAANRDHRRFPPDGDVFDIHREP-RQHLSFGVGAHFCLGNA
MMAR_4753|M.marinum_M EGSIMMMLIGAANRDHRQFPPDGDVFDIRREP-HQHLTFSVGTHYCLGSA
MUL_0324|M.ulcerans_Agy99 EGSIMMMLIGAANRDHRQFRPDGDVFNIRREP-HQHLTFSVGTHYCLGSA
MAV_2984|M.avium_104 EGSVMMMLIGSACRDEAQFGSDAGEFNIHRAV-RPHLTFSMGTHFCLGSA
Rv1256c|M.tuberculosis_H37Rv AGRRVLLLYGSANRDERQYGPDAAELDVTRCP-RNILTFSHGAHHCLGAA
MAB_1406c|M.abscessus_ATCC_199 AGRRALLLYGSANRDEREYGNDAAELDVLRKP-RNILTFSHGNHHCLGAA
Mb0789c|M.bovis_AF2122/97 EGEVLLLLPGSANRDDRVFD-DPDDYRIGREIGCKLVSFGSGAHFCLGAH
MLBr_02088|M.leprae_Br4923 EGDTMVLLLAAANRDPAVYS-RPDEFDPDRPS-SRHLAFAVGSHFCLGAA
* ::* .:* ** : * ::*. * *.*:*
Mflv_2431|M.gilvum_PYR-GCK LARLEGRIALEEILKRFPTWEVDWPNAVPSQTTAVRGWETMPTFV---
Mvan_4221|M.vanbaalenii_PYR-1 LARLEGKIALEEILKRFPTWEVDWPNAVPSQTTAVRGWESMPTIVS--
MSMEG_4829|M.smegmatis_MC2_155 LARLELRVALEEILKRFPEWEVDWDNARPSETAAVRGWAAMPTFVR--
TH_3021|M.thermoresistible__bu LARLEGRVALDEILNRFPEWEVDMSKAELSPTSTVRGWETMPATIP--
MMAR_4753|M.marinum_M LARLEGRIALEEILKRFPEWDVDLGNAKLSPTSTVRGWESMPAVFD--
MUL_0324|M.ulcerans_Agy99 LARLEGRIALEDILKRFPEWDVDLGNAKLSPTSTVRGWESMPAVFD--
MAV_2984|M.avium_104 LARLEGRVALEEILKRFPEWEVDLSRATLSPTSTVRGWECMPALVP--
Rv1256c|M.tuberculosis_H37Rv AARMQCRVALTELLARCPDFEVAESRIVWSGGSYVRRPLSVPFRVTS-
MAB_1406c|M.abscessus_ATCC_199 AARMQSRIALEELLTRIPDFEVDLDGVTWADGSYVRRPLTVPIRVR--
Mb0789c|M.bovis_AF2122/97 LARMEARVALGALLRRIRNYEVDDDNVVRVHSSNVRGFAHLPISVQAR
MLBr_02088|M.leprae_Br4923 LARLEATVTLSAISARFPQVQLAG-ELVYKPNVAMRGMSALPVQV---
**:: ::* : * :: :* :* .