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aa seq not available
Operon Prediction Model: Genebank
Paralogs
species | id | gene | e-value | identity (len) | annotation |
M. thermoresistible (build 8) | TH_2671 | - | - | 100% (400) | cytochrome P450 monooxygenase |
M. thermoresistible (build 8) | TH_4114 | - | e-132 | 56.41% (390) | PUTATIVE cytochrome P450 |
M. thermoresistible (build 8) | TH_3021 | - | e-130 | 55.75% (391) | PUTATIVE cytochrome P450 |
Closest Orthologs (e-value cutoff: 1e-4)
species | id | gene | e-value | identity (len) | annotation |
M. bovis AF2122 / 97 | Mb0789c | cyp123 | 4e-68 | 38.25% (400) | cytochrome P450 123 |
M. gilvum PYR-GCK | Mflv_1266 | - | 0.0 | 81.68% (393) | cytochrome P450 |
M. tuberculosis H37Rv | Rv0766c | cyp123 | 5e-68 | 38.25% (400) | cytochrome P450 123 |
M. leprae Br4923 | MLBr_02088 | - | 3e-45 | 32.74% (394) | putative cytochrome p450 |
M. abscessus ATCC 19977 | MAB_1216c | - | 2e-67 | 39.75% (395) | cytochrome P450 |
M. marinum M | MMAR_4753 | cyp189A7 | 1e-136 | 56.82% (396) | cytochrome P450 189A7 Cyp189A7 |
M. avium 104 | MAV_1389 | - | 1e-164 | 68.46% (390) | NikQ protein |
M. smegmatis MC2 155 | MSMEG_6622 | - | 0.0 | 82.71% (399) | cytochrome P450 monooxygenase |
M. ulcerans Agy99 | MUL_0324 | cyp189A7 | 1e-135 | 56.57% (396) | cytochrome P450 189A7 Cyp189A7 |
M. vanbaalenii PYR-1 | Mvan_3187 | - | 1e-132 | 57.91% (392) | cytochrome P450 |
CLUSTAL 2.0.9 multiple sequence alignment Mb0789c|M.bovis_AF2122/97 --------------------------MTVRVGDPE-LVLDPYDYDFHEDP Rv0766c|M.tuberculosis_H37Rv --------------------------MTVRVGDPE-LVLDPYDYDFHEDP MAB_1216c|M.abscessus_ATCC_199 --------------------------MTVAETSAVPLVFDPYDYDFHEDP Mflv_1266|M.gilvum_PYR-GCK -------------------------------MSG--LYYDPYNVEIDVLP MSMEG_6622|M.smegmatis_MC2_155 ----------------------------MRVLDE--LSYDPYDVEIDVDP TH_2671|M.thermoresistible__bu ----------------------------MRVLGGSRLYYDPYDIEIDRDP MAV_1389|M.avium_104 -------------------------------MTG--LYYDPWNREIDADP MMAR_4753|M.marinum_M ----------------------------MTVTAASDVYFDPYDVELNADP MUL_0324|M.ulcerans_Agy99 ----------------------------MTVTAASDVYFDPYDVELNADP Mvan_3187|M.vanbaalenii_PYR-1 --------------------------------MADDLYYDPYDQGIVADP MLBr_02088|M.leprae_Br4923 MRTCVPTRTCVYAFIEYLSHNRPMGTNPPSLVEAQMLLLRLIDPGTRADP : : * Mb0789c|M.bovis_AF2122/97 YPYYRRLRDEAPLYRNEERNFWAVSRHHDVLQGFRDSTALSNAYGVSLDP Rv0766c|M.tuberculosis_H37Rv YPYYRRLRDEAPLYRNEERNFWAVSRHHDVLQGFRDSTALSNAYGVSLDP MAB_1216c|M.abscessus_ATCC_199 YPYYRRLRDEAPLYRNDDLKFWALSRHHDVLQGFRNSEALSNANGVSMDK Mflv_1266|M.gilvum_PYR-GCK YPVYKRLRDEAPLYYNEKFDFWALSRFAEVDSALKDVDNLSNAKGDILEV MSMEG_6622|M.smegmatis_MC2_155 YPTYRRLRDEAPVYFNGRFGFWALSRFADVEAALRDVDNLSNAKGDILEV TH_2671|M.thermoresistible__bu YPTYRVLRDEVPLYYNDKFDFWALSRYADVEAALRDVENLSSAKGDILEV MAV_1389|M.avium_104 YPIYKMLRNEAPLYYNERHDFWGLSRYDDVDAALRDPLRLSSAKGDILDV MMAR_4753|M.marinum_M YPMFRRLREEAPLYYNAQHGFYALSRFADVDRAIVDYQTFSSARGAILEI MUL_0324|M.ulcerans_Agy99 YPMFRRLREEAPLYYNAQHGFYALSRFADVDRAIVDYQTFSSARGAILEF Mvan_3187|M.vanbaalenii_PYR-1 YPTYARLRDEAPLYYNGRYDFWALSRHADVEKALQDWSTFSNSRSDILEL MLBr_02088|M.leprae_Br4923 FPVYRALIDYGPMQLPG-MPLTVFSSFSDCDEALRHPLSASDRLKATLAQ :* : * : *: : .* . : .: . *. : Mb0789c|M.bovis_AF2122/97 SSRTSEAYR----VMSMLAMDDPAHLRMRTLVSKGFTPRRIRELEPQVLE Rv0766c|M.tuberculosis_H37Rv SSRTSEAYR----VMSMLAMDDPAHLRMRTLVSKGFTPRRIRELEPQVLE MAB_1216c|M.abscessus_ATCC_199 ASFGPHAKL----VMSFLAMDDPEHLRLRALVSKGFTPRRIRELEGQVVA Mflv_1266|M.gilvum_PYR-GCK VKAEPVMP-----DGVFINEDPPVHTVHRLLVSRAFTPRKMKAIEEQVRA MSMEG_6622|M.smegmatis_MC2_155 VKAEPKMP-----LGVFINEDPPLHTVHRLLVSRAFTPRKMRAIEDQIRT TH_2671|M.thermoresistible__bu VKAEPVMP-----LGVFIHEDPPLHTVHRLLVSRAFTPRKMAAIEDQVRA MAV_1389|M.avium_104 VKADPVMP-----PGVFINEDPPLHTIHRALVARAFTPKKMRTLEDKIRA MMAR_4753|M.marinum_M IKANIDIP-----AGVLVFEDPPVHDVHRKLLSRMFTPRKINDLEPKIRE MUL_0324|M.ulcerans_Agy99 IKANIDIP-----AGVLVFEDPPVHDVHRKLLSRMFTPRKINDLEPKIRE Mvan_3187|M.vanbaalenii_PYR-1 IKSDFDMP-----KGVMMFEDPPEHTMLRGLMSRVFTPRRMAEIEDQIRR MLBr_02088|M.leprae_Br4923 QAIAAGAEPRPFYASSFMFLDPPDHTRLRKLVSKAFAPKVVQALEGDIAA :: * * * * *::: *:*: : :* .: Mb0789c|M.bovis_AF2122/97 LARIHLDSALQTES---FDFVAEFAGKLPMDVISELIGVPDTDRARIRAL Rv0766c|M.tuberculosis_H37Rv LARIHLDSALQTES---FDFVAEFAGKLPMDVISELIGVPDTDRARIRAL MAB_1216c|M.abscessus_ATCC_199 LARTHLDRALANASDRSFDFIAEYAGKLPMDVISELMGVPESDRARIREL Mflv_1266|M.gilvum_PYR-GCK FCQACLDPLQGGDR---FDFTLDLGAEMPMRVIGMLVGMPDSLQRSVRKA MSMEG_6622|M.smegmatis_MC2_155 FCAACLDPLTSGDR---FDFTLDLGAEMPMRVIGMLIGIPEELQRSVRKV TH_2671|M.thermoresistible__bu FCAACLDPLNAGDR---FDFTRDLGAEMPMRVIGMLVGMPDSLQREVRSV MAV_1389|M.avium_104 FCVASLDMVADSDR---FDFVEDLGAELPMRTIGMLLGIPDADQPSVREH MMAR_4753|M.marinum_M FCARSLDPLIGSGR---FDFVADLGAQMPMRVIGMLLGVPEEDQEAARDF MUL_0324|M.ulcerans_Agy99 FCARSLDPLIGSGR---FDFVADLGAQMPMRVIGMLLGVPEEDQEAARDF Mvan_3187|M.vanbaalenii_PYR-1 YCVNCLDPLVGSDG---FDVIAELAAMMPMRVIGMLLGIPESEQVSVRDA MLBr_02088|M.leprae_Br4923 LVDSLLDKGAAAGQ---FDVIADLAFPLAVAVICRLLGVPYEDAPEFGRV ** **. : . :.: .* *:*:* Mb0789c|M.bovis_AF2122/97 ADAVLHRED-------GVADVPPPAMAASIELMRYYADLIAEFRRRPANN Rv0766c|M.tuberculosis_H37Rv ADAVLHRED-------GVADVPPPAMAASIELMRYYADLIAEFRRRPANN MAB_1216c|M.abscessus_ATCC_199 ADGVMHRED-------GLADVPPEAIQASFDLMTYYIEMVRERRRRPTED Mflv_1266|M.gilvum_PYR-GCK AGARLRNKP-------GEP--LPVK-KDNYFNGNMFRDYVAWRKDNPSDD MSMEG_6622|M.smegmatis_MC2_155 AGQRLRNKP-------GEP--LPVN-KDNYFNGNMFRDYVEWRAQNPSDD TH_2671|M.thermoresistible__bu AGRRLRNQP-------GRP--LPVS-RDNYFNGDMFRDYVAWRERHPSDD MAV_1389|M.avium_104 ARATLHNDT-------GGP--MPIR-KDHYFDGDMFSDYVEWRKQNPSDD MMAR_4753|M.marinum_M ATAQLRTEA-------GKP--MKAS-ADGMVSGDFFAHYIDWRAEHPSSD MUL_0324|M.ulcerans_Agy99 ATAQLRTEA-------GKP--MKAS-ADGMVSGDFFAHYIDWRAEHPSSD Mvan_3187|M.vanbaalenii_PYR-1 NDANLRTRP-------GAP--MKVADPDRIADGRIYSDYVEWRAANPSDD MLBr_02088|M.leprae_Br4923 SALLVQSVDPFITITGEPPEATEERLRAGVWLRDYLEQLVKCRRGTPGED :: . . : * .: Mb0789c|M.bovis_AF2122/97 LTSALLAAELDGD-----RLSDQEIMAFLFLMVIAGNETTTKLLANAVYW Rv0766c|M.tuberculosis_H37Rv LTSALLAAELDGD-----RLSDQEIMAFLFLMVIAGNETTTKLLANAVYW MAB_1216c|M.abscessus_ATCC_199 LTSALLQAEIDGD-----RLTDEEVLAFLFLMVIAGNETTTKLLANAVYW Mflv_1266|M.gilvum_PYR-GCK LVTELLNVEFEDVDGSRRKLRDEELLVFLGVIANAGSETVGRLFGWLGKV MSMEG_6622|M.smegmatis_MC2_155 LVTELLNVEFEDVTGTTRKLSSEELLVFLGVIANAGTETVGRLFGWLGKL TH_2671|M.thermoresistible__bu LVTELLNVEFEDVSGTVRRLRTEELLVFLGVIANAGTETVGRLFGWLGKL MAV_1389|M.avium_104 LITELLSVDFEDQSGTVRRLTTPELLIFLAVIAGAGVETTGRLFGWMGKV MMAR_4753|M.marinum_M IMTELLNAEFEDETGTVRRLRRDELLTYVSVVSGAGNETTTRLIGWAGKV MUL_0324|M.ulcerans_Agy99 IMTELLNAEFEDETGTVRRLRRDELLTYVSVVSGAGNETTTRLIGWAGKV Mvan_3187|M.vanbaalenii_PYR-1 LMTALLNVEFTDEAGVHRKLTRKEVLHYTQVVAGAGNETTGRLIGWLAKV MLBr_02088|M.leprae_Br4923 LISRLIELDESGD-----QLTEEEIIATCGLLLVAGHETTVNLIANAVLA : : *: : . :* *:: :: ** **. .*:. Mb0789c|M.bovis_AF2122/97 AAHHPGQLARVFADHSRIPMWVEETLRYDTSSQILARTVAHDLTLYDTTI Rv0766c|M.tuberculosis_H37Rv AAHHPGQLARVFADHSRIPMWVEETLRYDTSSQILARTVAHDLTLYDTTI MAB_1216c|M.abscessus_ATCC_199 GHRNPDQLATVHADHDRIPLWVEESLRYDTSSQILARTVAEDITVYDTKI Mflv_1266|M.gilvum_PYR-GCK LADHPDARRELAADPSLIPGAIEEILRMEPPVHNIARYVAKDVTYHGQTV MSMEG_6622|M.smegmatis_MC2_155 LGEHPDQRRALVADPSLIPGAVEEVLRYEPPVHNIARYVSADVDYHGQTI TH_2671|M.thermoresistible__bu LGEHPDQRRELARDPALIPGAVEEVLRYESPVHNIARYVANDVEYHGQTV MAV_1389|M.avium_104 LADHPDQRKELAEDRSLIPAAVEELLRYEPPGPSVARYVTEDVEFHGQTV MMAR_4753|M.marinum_M LAEHPDQRRALVEDPSLIPQAVEELLRYEAPAPHVARYVTRDLRYYGESV MUL_0324|M.ulcerans_Agy99 LAEHPDQRRALVEDPSLIPQAVEELLRYEAPAPHVARYVTRDLRYYGQSV Mvan_3187|M.vanbaalenii_PYR-1 LAEHPQQRREIVEDRSLLGRAVDETLRFEPTGPHVARYLARDFEYDGTTV MLBr_02088|M.leprae_Br4923 MLRNPSQWKALSSNPQRAPLVVEETLRYDPAIHLIGRVAAKDMTIGQTTL :* : : ::* ** :.. :.* : *. .: Mb0789c|M.bovis_AF2122/97 PEGEVLLLLPGSANRDDRVFD-DPDDYRIGREIGCKLVSFGSGAHFCLGA Rv0766c|M.tuberculosis_H37Rv PEGEVLLLLPGSANRDDRVFD-DPDDYRIGREIGCKLVSFGSGAHFCLGA MAB_1216c|M.abscessus_ATCC_199 PAGDILLLLPGSANRDDRVFD-DADQYRIGREIGAKLVSFGSGAHFCLGA Mflv_1266|M.gilvum_PYR-GCK PAGSALLLMAGAANRDERRFD-NPDVFDIRRSP--NHLTFGRGAHFCLGT MSMEG_6622|M.smegmatis_MC2_155 PAGSALLLMTGAANRDERRFD-DPDRFDIRRSP--NHLSFGRGAHFCLGA TH_2671|M.thermoresistible__bu PAGSALLLMAGAANRDERRFE-DPDRFDIHRSSG-SHLAFGRGTHFCLGA MAV_1389|M.avium_104 PSGSAMLLMLSSANRDERRFD-HPDRFDIHRKPG-RHLTFGRGVHFCLGA MMAR_4753|M.marinum_M PEGSIMMMLIGAANRDHRQFPPDGDVFDIRREPH-QHLTFSVGTHYCLGS MUL_0324|M.ulcerans_Agy99 PEGSIMMMLIGAANRDHRQFRPDGDVFNIRREPH-QHLTFSVGTHYCLGS Mvan_3187|M.vanbaalenii_PYR-1 PAGSAILLLFGAANRDERRYR-NPDTFDIHRDNI-SHLTFGKGLHYCLGA MLBr_02088|M.leprae_Br4923 TEGDTMVLLLAAANRDPAVYS-RPDEFDPDRPSS-RHLAFAVGSHFCLGA . *. :::: .:**** : * : * ::*. * *:***: Mb0789c|M.bovis_AF2122/97 HLARMEARVALGALLRRIRNYEVDDDNVVRVHSSNVRGFAHLPISVQAR- Rv0766c|M.tuberculosis_H37Rv HLARMEARVALGALLRRIRNYEVDDDNVVRVHSSNVRGFAHLPISVQAR- MAB_1216c|M.abscessus_ATCC_199 HLARMEAKVALTELFTRISGYEIDERNSVRVHSSNVRGFAHLPMTVQLRE Mflv_1266|M.gilvum_PYR-GCK SLARLEGRIALEEILKRWPDWTFDEDNAHRAPTATVRGWDSMPAIVG--- MSMEG_6622|M.smegmatis_MC2_155 SLARVEGRVALEEILKRWPDWTVDMGNAVRAPTATVRGWDSMPAIVG--- TH_2671|M.thermoresistible__bu SLARLEGRVALEEILKRWPDWTIDADNAVRAPTATVRGWDSMPAVLG--- MAV_1389|M.avium_104 PLARLEGRIGLEEVLNRWPEWEIDMDNARRSRTSTVRGWDSMPAIVT--- MMAR_4753|M.marinum_M ALARLEGRIALEEILKRFPEWDVDLGNAKLSPTSTVRGWESMPAVFD--- MUL_0324|M.ulcerans_Agy99 ALARLEGRIALEDILKRFPEWDVDLGNAKLSPTSTVRGWESMPAVFD--- Mvan_3187|M.vanbaalenii_PYR-1 NLARLEGRVALDELLNRWPEWNIDYDTARLAPTSTVRGWEHLRMLVG--- MLBr_02088|M.leprae_Br4923 ALARLEATVTLSAISARFPQVQLAG-ELVYKPNVAMRGMSALPVQV---- ***:*. : * : * . . :** : . Mb0789c|M.bovis_AF2122/97 -- Rv0766c|M.tuberculosis_H37Rv -- MAB_1216c|M.abscessus_ATCC_199 GR Mflv_1266|M.gilvum_PYR-GCK -- MSMEG_6622|M.smegmatis_MC2_155 -- TH_2671|M.thermoresistible__bu -- MAV_1389|M.avium_104 -- MMAR_4753|M.marinum_M -- MUL_0324|M.ulcerans_Agy99 -- Mvan_3187|M.vanbaalenii_PYR-1 -- MLBr_02088|M.leprae_Br4923 --