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M. thermoresistible (build 8) TH_2671 (-)

annotation: cytochrome P450 monooxygenase
coordinates: 3136523 - 3137722
length: 400

aa seq not available

Operon Prediction Model: Genebank

Paralogs
speciesidgenee-valueidentity (len)annotation
M. thermoresistible (build 8)TH_2671--100% (400)cytochrome P450 monooxygenase
M. thermoresistible (build 8)TH_4114-e-13256.41% (390) PUTATIVE cytochrome P450
M. thermoresistible (build 8)TH_3021-e-13055.75% (391) PUTATIVE cytochrome P450

Closest Orthologs (e-value cutoff: 1e-4)
speciesidgenee-valueidentity (len)annotation
M. bovis AF2122 / 97Mb0789ccyp1234e-6838.25% (400) cytochrome P450 123
M. gilvum PYR-GCKMflv_1266-0.081.68% (393) cytochrome P450
M. tuberculosis H37RvRv0766ccyp1235e-6838.25% (400) cytochrome P450 123
M. leprae Br4923MLBr_02088-3e-4532.74% (394) putative cytochrome p450
M. abscessus ATCC 19977MAB_1216c-2e-6739.75% (395) cytochrome P450
M. marinum MMMAR_4753cyp189A71e-13656.82% (396) cytochrome P450 189A7 Cyp189A7
M. avium 104MAV_1389-1e-16468.46% (390) NikQ protein
M. smegmatis MC2 155MSMEG_6622-0.082.71% (399) cytochrome P450 monooxygenase
M. ulcerans Agy99MUL_0324cyp189A71e-13556.57% (396) cytochrome P450 189A7 Cyp189A7
M. vanbaalenii PYR-1Mvan_3187-1e-13257.91% (392) cytochrome P450

CLUSTAL 2.0.9 multiple sequence alignment


Mb0789c|M.bovis_AF2122/97           --------------------------MTVRVGDPE-LVLDPYDYDFHEDP
Rv0766c|M.tuberculosis_H37Rv        --------------------------MTVRVGDPE-LVLDPYDYDFHEDP
MAB_1216c|M.abscessus_ATCC_199      --------------------------MTVAETSAVPLVFDPYDYDFHEDP
Mflv_1266|M.gilvum_PYR-GCK          -------------------------------MSG--LYYDPYNVEIDVLP
MSMEG_6622|M.smegmatis_MC2_155      ----------------------------MRVLDE--LSYDPYDVEIDVDP
TH_2671|M.thermoresistible__bu      ----------------------------MRVLGGSRLYYDPYDIEIDRDP
MAV_1389|M.avium_104                -------------------------------MTG--LYYDPWNREIDADP
MMAR_4753|M.marinum_M               ----------------------------MTVTAASDVYFDPYDVELNADP
MUL_0324|M.ulcerans_Agy99           ----------------------------MTVTAASDVYFDPYDVELNADP
Mvan_3187|M.vanbaalenii_PYR-1       --------------------------------MADDLYYDPYDQGIVADP
MLBr_02088|M.leprae_Br4923          MRTCVPTRTCVYAFIEYLSHNRPMGTNPPSLVEAQMLLLRLIDPGTRADP
                                                                        :     :      *

Mb0789c|M.bovis_AF2122/97           YPYYRRLRDEAPLYRNEERNFWAVSRHHDVLQGFRDSTALSNAYGVSLDP
Rv0766c|M.tuberculosis_H37Rv        YPYYRRLRDEAPLYRNEERNFWAVSRHHDVLQGFRDSTALSNAYGVSLDP
MAB_1216c|M.abscessus_ATCC_199      YPYYRRLRDEAPLYRNDDLKFWALSRHHDVLQGFRNSEALSNANGVSMDK
Mflv_1266|M.gilvum_PYR-GCK          YPVYKRLRDEAPLYYNEKFDFWALSRFAEVDSALKDVDNLSNAKGDILEV
MSMEG_6622|M.smegmatis_MC2_155      YPTYRRLRDEAPVYFNGRFGFWALSRFADVEAALRDVDNLSNAKGDILEV
TH_2671|M.thermoresistible__bu      YPTYRVLRDEVPLYYNDKFDFWALSRYADVEAALRDVENLSSAKGDILEV
MAV_1389|M.avium_104                YPIYKMLRNEAPLYYNERHDFWGLSRYDDVDAALRDPLRLSSAKGDILDV
MMAR_4753|M.marinum_M               YPMFRRLREEAPLYYNAQHGFYALSRFADVDRAIVDYQTFSSARGAILEI
MUL_0324|M.ulcerans_Agy99           YPMFRRLREEAPLYYNAQHGFYALSRFADVDRAIVDYQTFSSARGAILEF
Mvan_3187|M.vanbaalenii_PYR-1       YPTYARLRDEAPLYYNGRYDFWALSRHADVEKALQDWSTFSNSRSDILEL
MLBr_02088|M.leprae_Br4923          FPVYRALIDYGPMQLPG-MPLTVFSSFSDCDEALRHPLSASDRLKATLAQ
                                    :* :  * :  *:       :  .* . :   .: .    *.     :  

Mb0789c|M.bovis_AF2122/97           SSRTSEAYR----VMSMLAMDDPAHLRMRTLVSKGFTPRRIRELEPQVLE
Rv0766c|M.tuberculosis_H37Rv        SSRTSEAYR----VMSMLAMDDPAHLRMRTLVSKGFTPRRIRELEPQVLE
MAB_1216c|M.abscessus_ATCC_199      ASFGPHAKL----VMSFLAMDDPEHLRLRALVSKGFTPRRIRELEGQVVA
Mflv_1266|M.gilvum_PYR-GCK          VKAEPVMP-----DGVFINEDPPVHTVHRLLVSRAFTPRKMKAIEEQVRA
MSMEG_6622|M.smegmatis_MC2_155      VKAEPKMP-----LGVFINEDPPLHTVHRLLVSRAFTPRKMRAIEDQIRT
TH_2671|M.thermoresistible__bu      VKAEPVMP-----LGVFIHEDPPLHTVHRLLVSRAFTPRKMAAIEDQVRA
MAV_1389|M.avium_104                VKADPVMP-----PGVFINEDPPLHTIHRALVARAFTPKKMRTLEDKIRA
MMAR_4753|M.marinum_M               IKANIDIP-----AGVLVFEDPPVHDVHRKLLSRMFTPRKINDLEPKIRE
MUL_0324|M.ulcerans_Agy99           IKANIDIP-----AGVLVFEDPPVHDVHRKLLSRMFTPRKINDLEPKIRE
Mvan_3187|M.vanbaalenii_PYR-1       IKSDFDMP-----KGVMMFEDPPEHTMLRGLMSRVFTPRRMAEIEDQIRR
MLBr_02088|M.leprae_Br4923          QAIAAGAEPRPFYASSFMFLDPPDHTRLRKLVSKAFAPKVVQALEGDIAA
                                                    ::  * * *   * *::: *:*: :  :* .:  

Mb0789c|M.bovis_AF2122/97           LARIHLDSALQTES---FDFVAEFAGKLPMDVISELIGVPDTDRARIRAL
Rv0766c|M.tuberculosis_H37Rv        LARIHLDSALQTES---FDFVAEFAGKLPMDVISELIGVPDTDRARIRAL
MAB_1216c|M.abscessus_ATCC_199      LARTHLDRALANASDRSFDFIAEYAGKLPMDVISELMGVPESDRARIREL
Mflv_1266|M.gilvum_PYR-GCK          FCQACLDPLQGGDR---FDFTLDLGAEMPMRVIGMLVGMPDSLQRSVRKA
MSMEG_6622|M.smegmatis_MC2_155      FCAACLDPLTSGDR---FDFTLDLGAEMPMRVIGMLIGIPEELQRSVRKV
TH_2671|M.thermoresistible__bu      FCAACLDPLNAGDR---FDFTRDLGAEMPMRVIGMLVGMPDSLQREVRSV
MAV_1389|M.avium_104                FCVASLDMVADSDR---FDFVEDLGAELPMRTIGMLLGIPDADQPSVREH
MMAR_4753|M.marinum_M               FCARSLDPLIGSGR---FDFVADLGAQMPMRVIGMLLGVPEEDQEAARDF
MUL_0324|M.ulcerans_Agy99           FCARSLDPLIGSGR---FDFVADLGAQMPMRVIGMLLGVPEEDQEAARDF
Mvan_3187|M.vanbaalenii_PYR-1       YCVNCLDPLVGSDG---FDVIAELAAMMPMRVIGMLLGIPESEQVSVRDA
MLBr_02088|M.leprae_Br4923          LVDSLLDKGAAAGQ---FDVIADLAFPLAVAVICRLLGVPYEDAPEFGRV
                                         **          **.  : .  :.: .*  *:*:*          

Mb0789c|M.bovis_AF2122/97           ADAVLHRED-------GVADVPPPAMAASIELMRYYADLIAEFRRRPANN
Rv0766c|M.tuberculosis_H37Rv        ADAVLHRED-------GVADVPPPAMAASIELMRYYADLIAEFRRRPANN
MAB_1216c|M.abscessus_ATCC_199      ADGVMHRED-------GLADVPPEAIQASFDLMTYYIEMVRERRRRPTED
Mflv_1266|M.gilvum_PYR-GCK          AGARLRNKP-------GEP--LPVK-KDNYFNGNMFRDYVAWRKDNPSDD
MSMEG_6622|M.smegmatis_MC2_155      AGQRLRNKP-------GEP--LPVN-KDNYFNGNMFRDYVEWRAQNPSDD
TH_2671|M.thermoresistible__bu      AGRRLRNQP-------GRP--LPVS-RDNYFNGDMFRDYVAWRERHPSDD
MAV_1389|M.avium_104                ARATLHNDT-------GGP--MPIR-KDHYFDGDMFSDYVEWRKQNPSDD
MMAR_4753|M.marinum_M               ATAQLRTEA-------GKP--MKAS-ADGMVSGDFFAHYIDWRAEHPSSD
MUL_0324|M.ulcerans_Agy99           ATAQLRTEA-------GKP--MKAS-ADGMVSGDFFAHYIDWRAEHPSSD
Mvan_3187|M.vanbaalenii_PYR-1       NDANLRTRP-------GAP--MKVADPDRIADGRIYSDYVEWRAANPSDD
MLBr_02088|M.leprae_Br4923          SALLVQSVDPFITITGEPPEATEERLRAGVWLRDYLEQLVKCRRGTPGED
                                        ::            .                  . :      * .:

Mb0789c|M.bovis_AF2122/97           LTSALLAAELDGD-----RLSDQEIMAFLFLMVIAGNETTTKLLANAVYW
Rv0766c|M.tuberculosis_H37Rv        LTSALLAAELDGD-----RLSDQEIMAFLFLMVIAGNETTTKLLANAVYW
MAB_1216c|M.abscessus_ATCC_199      LTSALLQAEIDGD-----RLTDEEVLAFLFLMVIAGNETTTKLLANAVYW
Mflv_1266|M.gilvum_PYR-GCK          LVTELLNVEFEDVDGSRRKLRDEELLVFLGVIANAGSETVGRLFGWLGKV
MSMEG_6622|M.smegmatis_MC2_155      LVTELLNVEFEDVTGTTRKLSSEELLVFLGVIANAGTETVGRLFGWLGKL
TH_2671|M.thermoresistible__bu      LVTELLNVEFEDVSGTVRRLRTEELLVFLGVIANAGTETVGRLFGWLGKL
MAV_1389|M.avium_104                LITELLSVDFEDQSGTVRRLTTPELLIFLAVIAGAGVETTGRLFGWMGKV
MMAR_4753|M.marinum_M               IMTELLNAEFEDETGTVRRLRRDELLTYVSVVSGAGNETTTRLIGWAGKV
MUL_0324|M.ulcerans_Agy99           IMTELLNAEFEDETGTVRRLRRDELLTYVSVVSGAGNETTTRLIGWAGKV
Mvan_3187|M.vanbaalenii_PYR-1       LMTALLNVEFTDEAGVHRKLTRKEVLHYTQVVAGAGNETTGRLIGWLAKV
MLBr_02088|M.leprae_Br4923          LISRLIELDESGD-----QLTEEEIIATCGLLLVAGHETTVNLIANAVLA
                                    : : *:  :  .      :*   *::    ::  ** **. .*:.     

Mb0789c|M.bovis_AF2122/97           AAHHPGQLARVFADHSRIPMWVEETLRYDTSSQILARTVAHDLTLYDTTI
Rv0766c|M.tuberculosis_H37Rv        AAHHPGQLARVFADHSRIPMWVEETLRYDTSSQILARTVAHDLTLYDTTI
MAB_1216c|M.abscessus_ATCC_199      GHRNPDQLATVHADHDRIPLWVEESLRYDTSSQILARTVAEDITVYDTKI
Mflv_1266|M.gilvum_PYR-GCK          LADHPDARRELAADPSLIPGAIEEILRMEPPVHNIARYVAKDVTYHGQTV
MSMEG_6622|M.smegmatis_MC2_155      LGEHPDQRRALVADPSLIPGAVEEVLRYEPPVHNIARYVSADVDYHGQTI
TH_2671|M.thermoresistible__bu      LGEHPDQRRELARDPALIPGAVEEVLRYESPVHNIARYVANDVEYHGQTV
MAV_1389|M.avium_104                LADHPDQRKELAEDRSLIPAAVEELLRYEPPGPSVARYVTEDVEFHGQTV
MMAR_4753|M.marinum_M               LAEHPDQRRALVEDPSLIPQAVEELLRYEAPAPHVARYVTRDLRYYGESV
MUL_0324|M.ulcerans_Agy99           LAEHPDQRRALVEDPSLIPQAVEELLRYEAPAPHVARYVTRDLRYYGQSV
Mvan_3187|M.vanbaalenii_PYR-1       LAEHPQQRREIVEDRSLLGRAVDETLRFEPTGPHVARYLARDFEYDGTTV
MLBr_02088|M.leprae_Br4923          MLRNPSQWKALSSNPQRAPLVVEETLRYDPAIHLIGRVAAKDMTIGQTTL
                                       :*     :  :       ::* ** :..   :.*  : *.     .:

Mb0789c|M.bovis_AF2122/97           PEGEVLLLLPGSANRDDRVFD-DPDDYRIGREIGCKLVSFGSGAHFCLGA
Rv0766c|M.tuberculosis_H37Rv        PEGEVLLLLPGSANRDDRVFD-DPDDYRIGREIGCKLVSFGSGAHFCLGA
MAB_1216c|M.abscessus_ATCC_199      PAGDILLLLPGSANRDDRVFD-DADQYRIGREIGAKLVSFGSGAHFCLGA
Mflv_1266|M.gilvum_PYR-GCK          PAGSALLLMAGAANRDERRFD-NPDVFDIRRSP--NHLTFGRGAHFCLGT
MSMEG_6622|M.smegmatis_MC2_155      PAGSALLLMTGAANRDERRFD-DPDRFDIRRSP--NHLSFGRGAHFCLGA
TH_2671|M.thermoresistible__bu      PAGSALLLMAGAANRDERRFE-DPDRFDIHRSSG-SHLAFGRGTHFCLGA
MAV_1389|M.avium_104                PSGSAMLLMLSSANRDERRFD-HPDRFDIHRKPG-RHLTFGRGVHFCLGA
MMAR_4753|M.marinum_M               PEGSIMMMLIGAANRDHRQFPPDGDVFDIRREPH-QHLTFSVGTHYCLGS
MUL_0324|M.ulcerans_Agy99           PEGSIMMMLIGAANRDHRQFRPDGDVFNIRREPH-QHLTFSVGTHYCLGS
Mvan_3187|M.vanbaalenii_PYR-1       PAGSAILLLFGAANRDERRYR-NPDTFDIHRDNI-SHLTFGKGLHYCLGA
MLBr_02088|M.leprae_Br4923          TEGDTMVLLLAAANRDPAVYS-RPDEFDPDRPSS-RHLAFAVGSHFCLGA
                                    . *. :::: .:****   :    * :   *      ::*. * *:***:

Mb0789c|M.bovis_AF2122/97           HLARMEARVALGALLRRIRNYEVDDDNVVRVHSSNVRGFAHLPISVQAR-
Rv0766c|M.tuberculosis_H37Rv        HLARMEARVALGALLRRIRNYEVDDDNVVRVHSSNVRGFAHLPISVQAR-
MAB_1216c|M.abscessus_ATCC_199      HLARMEAKVALTELFTRISGYEIDERNSVRVHSSNVRGFAHLPMTVQLRE
Mflv_1266|M.gilvum_PYR-GCK          SLARLEGRIALEEILKRWPDWTFDEDNAHRAPTATVRGWDSMPAIVG---
MSMEG_6622|M.smegmatis_MC2_155      SLARVEGRVALEEILKRWPDWTVDMGNAVRAPTATVRGWDSMPAIVG---
TH_2671|M.thermoresistible__bu      SLARLEGRVALEEILKRWPDWTIDADNAVRAPTATVRGWDSMPAVLG---
MAV_1389|M.avium_104                PLARLEGRIGLEEVLNRWPEWEIDMDNARRSRTSTVRGWDSMPAIVT---
MMAR_4753|M.marinum_M               ALARLEGRIALEEILKRFPEWDVDLGNAKLSPTSTVRGWESMPAVFD---
MUL_0324|M.ulcerans_Agy99           ALARLEGRIALEDILKRFPEWDVDLGNAKLSPTSTVRGWESMPAVFD---
Mvan_3187|M.vanbaalenii_PYR-1       NLARLEGRVALDELLNRWPEWNIDYDTARLAPTSTVRGWEHLRMLVG---
MLBr_02088|M.leprae_Br4923          ALARLEATVTLSAISARFPQVQLAG-ELVYKPNVAMRGMSALPVQV----
                                     ***:*. : *  :  *     .         .  :**   :   .    

Mb0789c|M.bovis_AF2122/97           --
Rv0766c|M.tuberculosis_H37Rv        --
MAB_1216c|M.abscessus_ATCC_199      GR
Mflv_1266|M.gilvum_PYR-GCK          --
MSMEG_6622|M.smegmatis_MC2_155      --
TH_2671|M.thermoresistible__bu      --
MAV_1389|M.avium_104                --
MMAR_4753|M.marinum_M               --
MUL_0324|M.ulcerans_Agy99           --
Mvan_3187|M.vanbaalenii_PYR-1       --
MLBr_02088|M.leprae_Br4923          --