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aa seq not available
Operon Prediction Model: Genebank
Paralogs
species | id | gene | e-value | identity (len) | annotation |
M. thermoresistible (build 8) | TH_4114 | - | - | 100% (400) | cytochrome P450 |
M. thermoresistible (build 8) | TH_3021 | - | e-137 | 58.88% (394) | PUTATIVE cytochrome P450 |
M. thermoresistible (build 8) | TH_2671 | - | e-132 | 56.41% (390) | PUTATIVE cytochrome P450 monooxygenase |
Closest Orthologs (e-value cutoff: 1e-4)
species | id | gene | e-value | identity (len) | annotation |
M. bovis AF2122 / 97 | Mb0789c | cyp123 | 6e-70 | 39.04% (397) | cytochrome P450 123 |
M. gilvum PYR-GCK | Mflv_1257 | - | 1e-134 | 57.00% (393) | cytochrome P450 |
M. tuberculosis H37Rv | Rv0766c | cyp123 | 6e-70 | 39.04% (397) | cytochrome P450 123 |
M. leprae Br4923 | MLBr_02088 | - | 5e-42 | 32.49% (397) | putative cytochrome p450 |
M. abscessus ATCC 19977 | MAB_1216c | - | 1e-67 | 39.26% (405) | cytochrome P450 |
M. marinum M | MMAR_0928 | cyp189A6 | 0.0 | 82.44% (393) | cytochrome P450 189A6 Cyp189A6 |
M. avium 104 | MAV_0366 | - | 0.0 | 84.56% (395) | cytochrome P450 superfamily protein |
M. smegmatis MC2 155 | MSMEG_3693 | - | 0.0 | 85.35% (389) | cytochrome P450 monooxygenase |
M. ulcerans Agy99 | MUL_0324 | cyp189A7 | 1e-137 | 57.18% (397) | cytochrome P450 189A7 Cyp189A7 |
M. vanbaalenii PYR-1 | Mvan_3187 | - | 0.0 | 84.01% (394) | cytochrome P450 |
CLUSTAL 2.0.9 multiple sequence alignment Mb0789c|M.bovis_AF2122/97 --------------------MTVRVGDPE-------LVLDPYDYDFHEDP Rv0766c|M.tuberculosis_H37Rv --------------------MTVRVGDPE-------LVLDPYDYDFHEDP MAB_1216c|M.abscessus_ATCC_199 --------------------MTVAETSAVP------LVFDPYDYDFHEDP MSMEG_3693|M.smegmatis_MC2_155 ---------------------MTVDDSGVVVTGVAGPYYDPYDVGIVADP Mvan_3187|M.vanbaalenii_PYR-1 ----------------------MADD----------LYYDPYDQGIVADP MMAR_0928|M.marinum_M --------------MATHIEAAQAHDT--------DVYYDPYDVNITANP MAV_0366|M.avium_104 --------------------MTVANDT--------AVYYDPYDIGIITDP TH_4114|M.thermoresistible__bu --------------------MATVETD---------VYYDPYDVDIVADP Mflv_1257|M.gilvum_PYR-GCK -------------------------MS--------DLYYDPWHVDIDIDP MUL_0324|M.ulcerans_Agy99 --------------------MTVTAAS--------DVYFDPYDVELNADP MLBr_02088|M.leprae_Br4923 MRTCVPTRTCVYAFIEYLSHNRPMGTNPPSLVEAQMLLLRLIDPGTRADP . :* Mb0789c|M.bovis_AF2122/97 YPYYRRLRDEAPLYRNEERNFWAVSRHHDVLQGFRDSTALSNAYGVSLDP Rv0766c|M.tuberculosis_H37Rv YPYYRRLRDEAPLYRNEERNFWAVSRHHDVLQGFRDSTALSNAYGVSLDP MAB_1216c|M.abscessus_ATCC_199 YPYYRRLRDEAPLYRNDDLKFWALSRHHDVLQGFRNSEALSNANGVSMDK MSMEG_3693|M.smegmatis_MC2_155 YPVYARLRDEAPLYHNERYGFWALSRHADVESALANWETFSNSRSDILEL Mvan_3187|M.vanbaalenii_PYR-1 YPTYARLRDEAPLYYNGRYDFWALSRHADVEKALQDWSTFSNSRSDILEL MMAR_0928|M.marinum_M YPTYARLREQAPLYYNQRYDFWAISRHADVEKALADWQTFSNSRSDILEL MAV_0366|M.avium_104 YPTYARLREEAPIYYNERYDFWALSRHSDVERALANWQVFSNRRSDILEL TH_4114|M.thermoresistible__bu YPVYARLRDEAPIYYNERYDFWALSRYADVEKALLNWETFSNSRSDILEL Mflv_1257|M.gilvum_PYR-GCK YPTYRRLRDEAPVYRNDEHGFWGLSRYADVDVALKDTTRLSSAKGDILEV MUL_0324|M.ulcerans_Agy99 YPMFRRLREEAPLYYNAQHGFYALSRFADVDRAIVDYQTFSSARGAILEF MLBr_02088|M.leprae_Br4923 FPVYRALIDYGPMQLPG-MPLTVFSSFSDCDEALRHPLSASDRLKATLAQ :* : * : .*: : .* . * .: . *. : Mb0789c|M.bovis_AF2122/97 SSRTSEAYR----VMSMLAMDDPAHLRMRTLVSKGFTPRRIRELEPQVLE Rv0766c|M.tuberculosis_H37Rv SSRTSEAYR----VMSMLAMDDPAHLRMRTLVSKGFTPRRIRELEPQVLE MAB_1216c|M.abscessus_ATCC_199 ASFGPHAKL----VMSFLAMDDPEHLRLRALVSKGFTPRRIRELEGQVVA MSMEG_3693|M.smegmatis_MC2_155 VKSDFDMP-----PGVMMFTDPPMHTMLRGLMSRVFTPRRMAEIEDQIRR Mvan_3187|M.vanbaalenii_PYR-1 IKSDFDMP-----KGVMMFEDPPEHTMLRGLMSRVFTPRRMAEIEDQIRR MMAR_0928|M.marinum_M IKSKYDMP-----PGVMMFEDPPVHTMLRGVMSRVFTPRRMAQLEDQIRR MAV_0366|M.avium_104 IQSKFDMP-----GGVMMFQDPPEHTVLRGLMSRVFTPRRMAALEDQIRQ TH_4114|M.thermoresistible__bu VQSDFDMP-----PGVMMFQDPPMHTMLRGLMSRVFTPRRMAALEEQIRA Mflv_1257|M.gilvum_PYR-GCK VMADPVMP-----PGIFINEDPPLHTIHRAIVARAFTPKKMRAIEDKIRA MUL_0324|M.ulcerans_Agy99 IKANIDIP-----AGVLVFEDPPVHDVHRKLLSRMFTPRKINDLEPKIRE MLBr_02088|M.leprae_Br4923 QAIAAGAEPRPFYASSFMFLDPPDHTRLRKLVSKAFAPKVVQALEGDIAA :: * * * * :::: *:*: : :* .: Mb0789c|M.bovis_AF2122/97 LARIHLDSALQTES---FDFVAEFAGKLPMDVISELIGVPDTDRARIR-- Rv0766c|M.tuberculosis_H37Rv LARIHLDSALQTES---FDFVAEFAGKLPMDVISELIGVPDTDRARIR-- MAB_1216c|M.abscessus_ATCC_199 LARTHLDRALANASDRSFDFIAEYAGKLPMDVISELMGVPESDRARIR-- MSMEG_3693|M.smegmatis_MC2_155 YCVRCLDPLVGSDR---FDIIAELASTMPMRVIGMLLGIPESEQIGVR-- Mvan_3187|M.vanbaalenii_PYR-1 YCVNCLDPLVGSDG---FDVIAELAAMMPMRVIGMLLGIPESEQVSVR-- MMAR_0928|M.marinum_M FCVRCLDPLVGRDS---FDIIAELASMMPMRVIGMLLGIPESDQIGVR-- MAV_0366|M.avium_104 YCIRCLDPLVGSSS---FDIIAELASMMPMRVIGMLLGIPESEQVSVR-- TH_4114|M.thermoresistible__bu YCVRCLDPLVGAEG---FDIIAELAAMMPMRVIGMLLGIPESDQISVR-- Mflv_1257|M.gilvum_PYR-GCK FCVACLDPLVGGDR---FDFVEDLGAELPMRTIGMLAGIPNSEQPAVR-- MUL_0324|M.ulcerans_Agy99 FCARSLDPLIGSGR---FDFVADLGAQMPMRVIGMLLGVPEEDQEAAR-- MLBr_02088|M.leprae_Br4923 LVDSLLDKGAAAGQ---FDVIADLAFPLAVAVICRLLGVPYEDAPEFGRV ** **.: : . :.: .* * *:* : Mb0789c|M.bovis_AF2122/97 -----ALADAVLHREDGVADVPPPAMAASIELMRYYADLIAEFRRRPANN Rv0766c|M.tuberculosis_H37Rv -----ALADAVLHREDGVADVPPPAMAASIELMRYYADLIAEFRRRPANN MAB_1216c|M.abscessus_ATCC_199 -----ELADGVMHREDGLADVPPEAIQASFDLMTYYIEMVRERRRRPTED MSMEG_3693|M.smegmatis_MC2_155 -----DANDANLRTKPGAP--MKVAQADKIADGRIYADYVEWRSKNPSDD Mvan_3187|M.vanbaalenii_PYR-1 -----DANDANLRTRPGAP--MKVADPDRIADGRIYSDYVEWRAANPSDD MMAR_0928|M.marinum_M -----DANDANLRTQPGTP--MKVARPDKIADGSIYADYIDWRAKNPSDD MAV_0366|M.avium_104 -----DANDANLRTKPGAP--LRVADADSIADGRIYADYVEWRSKNPSDD TH_4114|M.thermoresistible__bu -----DANDANLRTKPGAP--MKVADPGRIADGSIYAEYIDWRARNPSDD Mflv_1257|M.gilvum_PYR-GCK -----EHANEVLRNEAGKP--MAID-KDRYFTGEMFGEYIEWRENNPSDD MUL_0324|M.ulcerans_Agy99 -----DFATAQLRTEAGKP--MKAS-ADGMVSGDFFAHYIDWRAEHPSSD MLBr_02088|M.leprae_Br4923 SALLVQSVDPFITITGEPPEATEERLRAGVWLRDYLEQLVKCRRGTPGED : . . : * .: Mb0789c|M.bovis_AF2122/97 LTSALLAAELDGD-----RLSDQEIMAFLFLMVIAGNETTTKLLANAVYW Rv0766c|M.tuberculosis_H37Rv LTSALLAAELDGD-----RLSDQEIMAFLFLMVIAGNETTTKLLANAVYW MAB_1216c|M.abscessus_ATCC_199 LTSALLQAEIDGD-----RLTDEEVLAFLFLMVIAGNETTTKLLANAVYW MSMEG_3693|M.smegmatis_MC2_155 LMTALLGVEFTDEHGVTRKLTRKEVLHYTQVVAGAGNETTGRLIGWLAKV Mvan_3187|M.vanbaalenii_PYR-1 LMTALLNVEFTDEAGVHRKLTRKEVLHYTQVVAGAGNETTGRLIGWLAKV MMAR_0928|M.marinum_M LMTALLNVEFDDEHAVRRKLTRTEVLHYTQVVAGAGNETTGRLIGWLAKV MAV_0366|M.avium_104 LMTTLLNVEFDDEDGVRRKLTRKEVLHYTQVVAGAGNETTGRLIGWLAKV TH_4114|M.thermoresistible__bu LMTALLNVEFTDEHGVVRKLTRREVLHYTQVVAGAGNETTGRLIGWLAKV Mflv_1257|M.gilvum_PYR-GCK LITELLNVEFEDETGTVRKLTKQELTVFLAVVAGAGVETTGRLFGWMGKV MUL_0324|M.ulcerans_Agy99 IMTELLNAEFEDETGTVRRLRRDELLTYVSVVSGAGNETTTRLIGWAGKV MLBr_02088|M.leprae_Br4923 LISRLIELDESGD-----QLTEEEIIATCGLLLVAGHETTVNLIANAVLA : : *: : .: :* *: :: ** *** .*:. Mb0789c|M.bovis_AF2122/97 AAHHPGQLARVFADHSRIPMWVEETLRYDTSSQILARTVAH-DLTLYDTT Rv0766c|M.tuberculosis_H37Rv AAHHPGQLARVFADHSRIPMWVEETLRYDTSSQILARTVAH-DLTLYDTT MAB_1216c|M.abscessus_ATCC_199 GHRNPDQLATVHADHDRIPLWVEESLRYDTSSQILARTVAE-DITVYDTK MSMEG_3693|M.smegmatis_MC2_155 LAEHPDQRRQIEQDRSLLTRAVDETLRFEPTGPHVARWVAR-DFEAYGQT Mvan_3187|M.vanbaalenii_PYR-1 LAEHPQQRREIVEDRSLLGRAVDETLRFEPTGPHVARYLAR-DFEYDGTT MMAR_0928|M.marinum_M LAEHPDQRRQVHQDRSLLTRTVDETLRFEPTGPHVARFTLR-DYHCYDTT MAV_0366|M.avium_104 LAEHPDQRREVYRDRSLLTRTVDETLRFEPTGPHVARWMAA-DFECYGTT TH_4114|M.thermoresistible__bu LAEHPDQRRDVYEDRSLLGRVIEETLRFEPTGPHVARWMAR-DFECYGTT Mflv_1257|M.gilvum_PYR-GCK LAEHPDQRKELTSTPALIPSAIEELLRFEPPGPHVARYVATDDVTFHGVV MUL_0324|M.ulcerans_Agy99 LAEHPDQRRALVEDPSLIPQAVEELLRYEAPAPHVARYVTR-DLRYYGQS MLBr_02088|M.leprae_Br4923 MLRNPSQWKALSSNPQRAPLVVEETLRYDPAIHLIGRVAAK-DMTIGQTT .:* * : ::* **::.. :.* * Mb0789c|M.bovis_AF2122/97 IPEGEVLLLLPGSANRDDRVFD-DPDDYRIGREIGCKLVSFGSGAHFCLG Rv0766c|M.tuberculosis_H37Rv IPEGEVLLLLPGSANRDDRVFD-DPDDYRIGREIGCKLVSFGSGAHFCLG MAB_1216c|M.abscessus_ATCC_199 IPAGDILLLLPGSANRDDRVFD-DADQYRIGREIGAKLVSFGSGAHFCLG MSMEG_3693|M.smegmatis_MC2_155 VPAGSAMLLLFGAANRDPRRYT-DPDVFDIHRDNISHLT-FGKGLHYCLG Mvan_3187|M.vanbaalenii_PYR-1 VPAGSAILLLFGAANRDERRYR-NPDTFDIHRDNISHLT-FGKGLHYCLG MMAR_0928|M.marinum_M VPAGSAILMLFGAANRDPRRYH-DPDTFDIRRDNISHLT-FGKGVHYCLG MAV_0366|M.avium_104 VPAGSAMLLLFGAANRDPRRYT-DPDTFNIHRDNISHIT-FGKGVHYCLG TH_4114|M.thermoresistible__bu VPAGSAMLLLFGAANRDPRRYD-DPDTFNIHRERGSHLT-FGKGLHFCLG Mflv_1257|M.gilvum_PYR-GCK IPAGSPLLLMLASANRDERQFD-DPDRFDIHRKQGGHLT-FGRGAHFCVG MUL_0324|M.ulcerans_Agy99 VPEGSIMMMLIGAANRDHRQFRPDGDVFNIRREPHQHLT-FSVGTHYCLG MLBr_02088|M.leprae_Br4923 LTEGDTMVLLLAAANRDPAVYS-RPDEFDPDRPSSRHLA-FAVGSHFCLG :. *. :::: .:**** : * : * ::. *. * *:*:* Mb0789c|M.bovis_AF2122/97 AHLARMEARVALGALLRRIRNYEVDDDNVVRVHSSNVRGFAHLPISVQAR Rv0766c|M.tuberculosis_H37Rv AHLARMEARVALGALLRRIRNYEVDDDNVVRVHSSNVRGFAHLPISVQAR MAB_1216c|M.abscessus_ATCC_199 AHLARMEAKVALTELFTRISGYEIDERNSVRVHSSNVRGFAHLPMTVQLR MSMEG_3693|M.smegmatis_MC2_155 ANLARLEGRVALDELLNRFPEWDIDYSTARLAPTSTVRGWERLDVLVG-- Mvan_3187|M.vanbaalenii_PYR-1 ANLARLEGRVALDELLNRWPEWNIDYDTARLAPTSTVRGWEHLRMLVG-- MMAR_0928|M.marinum_M ANLARLEGRVALDELLNRWPQWDIDYDSLQLAPTSTVRGWERLRVLVS-- MAV_0366|M.avium_104 ANLARLEGRVALDELLNRWPEWDIDYDTAQLASTSTVRGWERLRIVVP-- TH_4114|M.thermoresistible__bu ANLARLEGRVALDELLNRWPEWDIDYDTAQLAPTSTVRGWERLRIVFP-- Mflv_1257|M.gilvum_PYR-GCK APLARLEGRVALEEVLKRWPEWDIDMSGARRSRTSTVRGWDSMPAVIR-- MUL_0324|M.ulcerans_Agy99 SALARLEGRIALEDILKRFPEWDVDLGNAKLSPTSTVRGWESMPAVFD-- MLBr_02088|M.leprae_Br4923 AALARLEATVTLSAISARFPQVQLAG-ELVYKPNVAMRGMSALPVQV--- : ***:*. ::* : * :: . :** : . Mb0789c|M.bovis_AF2122/97 --- Rv0766c|M.tuberculosis_H37Rv --- MAB_1216c|M.abscessus_ATCC_199 EGR MSMEG_3693|M.smegmatis_MC2_155 --- Mvan_3187|M.vanbaalenii_PYR-1 --- MMAR_0928|M.marinum_M --- MAV_0366|M.avium_104 --- TH_4114|M.thermoresistible__bu --- Mflv_1257|M.gilvum_PYR-GCK --- MUL_0324|M.ulcerans_Agy99 --- MLBr_02088|M.leprae_Br4923 ---