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aa seq not available
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. thermoresistible (build 8) | TH_2976 | - | - | 100% (406) | dioxygenase large subunit |
| M. thermoresistible (build 8) | TH_2967 | - | 5e-35 | 28.57% (427) | PUTATIVE putative Rieske (2Fe-2S) domain protein |
| M. thermoresistible (build 8) | TH_4380 | - | 2e-16 | 28.21% (195) | PUTATIVE putative Rieske (2Fe-2S) domain protein |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb3186c | - | 5e-17 | 28.35% (194) | dioxygenase |
| M. gilvum PYR-GCK | Mflv_1355 | - | 1e-43 | 30.34% (379) | Rieske (2Fe-2S) domain-containing protein |
| M. tuberculosis H37Rv | Rv3161c | - | 2e-17 | 28.87% (194) | dioxygenase |
| M. leprae Br4923 | - | - | - | - | - |
| M. abscessus ATCC 19977 | MAB_4370c | - | 3e-30 | 28.47% (418) | putative large terminal subunit of phenylpropionate dioxygenase |
| M. marinum M | MMAR_0212 | - | 2e-21 | 32.00% (200) | oxidoreductase |
| M. avium 104 | MAV_5084 | - | 0.0 | 85.43% (405) | dioxygenase large subunit |
| M. smegmatis MC2 155 | MSMEG_1908 | - | 6e-45 | 31.23% (381) | benzoate 1,2-dioxygenase alpha subunit |
| M. ulcerans Agy99 | MUL_3820 | - | 9e-16 | 32.02% (178) | ring-hydroxylating dioxygenase, large terminal subunit |
| M. vanbaalenii PYR-1 | Mvan_0488 | - | 7e-41 | 28.10% (427) | ring hydroxylating dioxygenase, alpha subunit |
CLUSTAL 2.0.9 multiple sequence alignment
Mb3186c|M.bovis_AF2122/97 -MLSTDNRAELGDILTDIGDYLDDNPPALS--------LPPAAYTSSELW
Rv3161c|M.tuberculosis_H37Rv -MLSTDNRAELGDILTDIGDYLDDNPPALS--------LPPAAYTSSELW
TH_2976|M.thermoresistible__bu --------------------LIRPD------------RVHGSLYTDPAIF
MAV_5084|M.avium_104 ---MTTVTDPAAGTAGRYERLIRPD------------KVHGSLYTDPSIF
Mflv_1355|M.gilvum_PYR-GCK MTQTTASPQPRTHLAAVLADAVIDDPEAG------VFRANRRIFTDEEIF
MSMEG_1908|M.smegmatis_MC2_155 -MTTHLSP---DHLENVLADAVIEDPAAG------VYRANRRIFTDDEIF
MAB_4370c|M.abscessus_ATCC_199 -MASLPRPVAVAQGALCRPQALVRDIDVSGLVDSHGGLLDRVIFTDGELY
Mvan_0488|M.vanbaalenii_PYR-1 -MTTETTGTADATDPYLR--RALREVADG----LKVGRLPARVVSDPALH
MMAR_0212|M.marinum_M ------MSTAAGNPARTRDEDAIGVPPASP------TLVPAQRYHSPAFA
MUL_3820|M.ulcerans_Agy99 --MDRDQLIDLTRRALKLARDKTTDLAPHQ------HAVDAREYTSLDRH
.
Mb3186c|M.bovis_AF2122/97 QLERERIFNRSWMLVAHVDQLAKTGDYVTVSVAGEPVMVVRDVDGQLHAL
Rv3161c|M.tuberculosis_H37Rv QLERERIFNRSWMLVAHVDQVAKTGDYVTVSVAGEPVMVVRDVDGQLHAL
TH_2976|M.thermoresistible__bu AEELRKIWYRTWVFVGHESEVSQPNDYVRKKLGLQDVIMTRDRDGEIHLL
MAV_5084|M.avium_104 AEELRKIWYRTWVFVGHESEVAQPNDYVRKKLGPQDVIMTRDRDGQIHLL
Mflv_1355|M.gilvum_PYR-GCK ELEMKHIFEGNWIYLAHESQVANPGDYFTTYIGRQPVVITRSKDGSLNCL
MSMEG_1908|M.smegmatis_MC2_155 ELEMKHIFEGNWVYLAHESQVPNPGDYFTTYIGRQPVVITRDRDGDLHCL
MAB_4370c|M.abscessus_ATCC_199 RQELRRVFAPSWLFLAHADQFHRPGDFFTTYMGEDPVIVSMDKNRRIRAF
Mvan_0488|M.vanbaalenii_PYR-1 TIEMERIFGRAWVFLGHESELAKSGDFVVRHIGADSVIVCRDNSGRIQAL
MMAR_0212|M.marinum_M QLEIERMWPKVWQLACMLDHVAAPGDYFEYRCGPYSVLIVHDCDGVLRAF
MUL_3820|M.ulcerans_Agy99 ERDRAMVLD-SPQLVGYSSELPGPDTYRTKTIMGRSILLTRAADRAVRAF
: : ... .. : ::: . :. :
Mb3186c|M.bovis_AF2122/97 SPICRHRLMLMVEPGAGRIDTLTCQYHLWRYGLDGRLRGAPHMAANLDFN
Rv3161c|M.tuberculosis_H37Rv SPICRHRLMLMVEPGAGRIDTLTCQYHLWRYGLDGRLRGAPHMAANLDFN
TH_2976|M.thermoresistible__bu LNRCSHRGNQVCADAKGNSSTFRCPYHGWTFRNTGELVGFPFF-KGYGTR
MAV_5084|M.avium_104 LNRCAHRGNQLCDDAQGNSGTFRCPYHGWTFRNTGELIGFPFF-RGYGGR
Mflv_1355|M.gilvum_PYR-GCK INACAHRGAMICRRKTDNRMTLTCPFHGWTFRNDGALLKVKDP-DGAGYP
MSMEG_1908|M.smegmatis_MC2_155 INACAHRGAMICRRKTDNRTTLTCPFHGWTFRNDGTLLKVKDP-DGAGYP
MAB_4370c|M.abscessus_ATCC_199 LNSCRHRGARVCRADYGVTRGFTCTYHGWAYDLEGKLISVPNE-EGYPDS
Mvan_0488|M.vanbaalenii_PYR-1 SNSCRHRGALVCRAEMGNTAHFQCPYHGWVYSNTGELVGVPAMSEAYPGG
MMAR_0212|M.marinum_M QNVCRHRGNSLCAGSGSGLRELKCGYHGWTWDLTGELRRVPNR-KGFG-S
MUL_3820|M.ulcerans_Agy99 DNVCLHRQSRVATG-CGTALRFTCPYHGWTYDNGGRLVGLPGREGFPGIA
* ** : . : * :* * : * *
Mb3186c|M.bovis_AF2122/97 RRECRLP------QFAVATWNGLVWINLDADA-EPIAAHLDLTD---DEF
Rv3161c|M.tuberculosis_H37Rv RRECRLP------QFAVATWNGLVWINLDADA-EPIAAHLDLTD---DEF
TH_2976|M.thermoresistible__bu KLDLPLG-----RVPRVDSYGGFVFGSFATEG-PTLREHLGAAAGEIDRL
MAV_5084|M.avium_104 KLDLTLG-----RVPRVDSYGGFVFGSFAPDG-PSLVEHLGAAAGEIDRL
Mflv_1355|M.gilvum_PYR-GCK EAFNVNGSHNMTTVARFESYRGFLFGSLNPDV-LPLTEHLGDATKIIDML
MSMEG_1908|M.smegmatis_MC2_155 DTFNSNGSHNMTNVARFEGYRGFLFGSLNPDV-LPLTEHLGDTTTVIDML
MAB_4370c|M.abscessus_ATCC_199 FSTDDWG---LVEVPHVDSYHGLIFGTWNPAP-VGLRESLGDMAWYMDAM
Mvan_0488|M.vanbaalenii_PYR-1 FDKSQWG---LRHIPHVDSYAGFIFGSVDPKA-PSLTDYLGDTTFYLDLI
MMAR_0212|M.marinum_M LHMPDFP----LLPVRVETWEGLVFVSLDVTA-MPLMDYLDPIPEDIAWC
MUL_3820|M.ulcerans_Agy99 VGSDGLT------ELPATEFAGFLWVSLHPAARLDVPAHLGPLAGELQSW
: *::: . : *.
Mb3186c|M.bovis_AF2122/97 AGYRLGEMVQVESWSHEWR--ANWKVAAEN-GHENYHVLGLHR-------
Rv3161c|M.tuberculosis_H37Rv AGYRLGEMVQVESWSHEWR--ANWKVAAEN-GHENYHVLGLHR-------
TH_2976|M.thermoresistible__bu LRLSPEGKVALDAGWLRHRTRANWKLLVEN-ETDGYHPQFVHG----GIF
MAV_5084|M.avium_104 TGLSPQGRIELTAGWLQHLTRANWKLLAEN-ETDGYHPQFVHG----SIF
Mflv_1355|M.gilvum_PYR-GCK VDQSPDG-LEVLRGSSTYTYDGNWKVQAEN-GADGYHVTATH-----WNY
MSMEG_1908|M.smegmatis_MC2_155 VDQSPDG-LEVLRGASTYTYDGNWKVQAEN-GADGYHVTATH-----WNY
MAB_4370c|M.abscessus_ATCC_199 LDHDSEG-TVVVGGVHKWVLDGNWKLAAEQFATDWYHVNMSHASALMVMA
Mvan_0488|M.vanbaalenii_PYR-1 AKKTAGG-LEVIGAPHRWVMSANWKTAADNFVGDSYHTLFAHR----SMV
MMAR_0212|M.marinum_M GLSDFRCYATLT-----VEVDANWKTIADG-YSETYHIQTLHP-----EL
MUL_3820|M.ulcerans_Agy99 GIGRWSPLGEKVLGSP-----IDWKLATDT-FAENYHFATVHR-------
:** .: : ** *
Mb3186c|M.bovis_AF2122/97 -------------QTLEPFVPGGGDLDVRQYSRWALRLRVPFTVPVEAKS
Rv3161c|M.tuberculosis_H37Rv -------------QTLEPFVPGGGDLDVRQYSRWALRLRVPFTVPVEAKS
TH_2976|M.thermoresistible__bu GVTGSTIGPLYSDSSTAVTRDLGGGHSENDLRPEFRKFAEPLRWFGTTES
MAV_5084|M.avium_104 GVTGSTIGPLYSDSSTAVTRDLGNGHSENDLRPEFRKFAQPMRWFGTTES
Mflv_1355|M.gilvum_PYR-GCK AATTSRRGTGESKNETKALDAGGWGKSGGGYWSFPHGHLCLWTWAANPQD
MSMEG_1908|M.smegmatis_MC2_155 AATTSRRTCGESKNDTKALDAGSWGKSGGGYWSFPHGHLCLWTWAANPQD
MAB_4370c|M.abscessus_ATCC_199 PQGKAPKDEIVHRTGRQYVDPNGHGAGFPVHPKNRFDARVVHQWTDYGAL
Mvan_0488|M.vanbaalenii_PYR-1 ELGMAPGDPNFASAPAEISLQNGHGVGVLGFPPTLADFPEYEGYPDEVVD
MMAR_0212|M.marinum_M LRCVDDIHAPQQIWRHAGKSDQPYGVPSPRFEGTLSDQEVWDAYVYTQGA
MUL_3820|M.ulcerans_Agy99 -------------RTFATIARSNCTVFDSYGPHHRLIFPLNTILELENVP
Mb3186c|M.bovis_AF2122/97 LQLNEVQKSNLVVLWTFPNSALAIAGERVVWF------------------
Rv3161c|M.tuberculosis_H37Rv LQLNEVQKSNLVVLWTFPNSALAIAGERVVWF------------------
TH_2976|M.thermoresistible__bu R-VPDYVAAMRARYGAEADQILIEGSPHVMIFPNLFIA--------EIQV
MAV_5084|M.avium_104 R-VPEYVKAMRQVHGAYADRVLIEGAPHVMIFPNLFIA--------EIQV
Mflv_1355|M.gilvum_PYR-GCK RPLWDKLDELKATHGDAKGEFMVKGSRNLCVYPNVYVMDQF-----STQI
MSMEG_1908|M.smegmatis_MC2_155 RPLWDRLDELKARFGDAKGEFMVKGSRNLCLYPNVYVMDQF-----STQI
MAB_4370c|M.abscessus_ATCC_199 RERLG-EARVQGPLTNG----HATVFPNLSYLPVNG------------SV
Mvan_0488|M.vanbaalenii_PYR-1 QMATSYPSPVHKDLMRRSSFIHGTVFPNLSFINVTLAQDHMSPPTPFITF
MMAR_0212|M.marinum_M LMGAAEGTPLPADERRPGQSVQDLIAARTRAFAATRGVDLEWADTDRITR
MUL_3820|M.ulcerans_Agy99 EGQWDPFHHMVVIYALFPNVVLSVTIANGELFR-----------------
.
Mb3186c|M.bovis_AF2122/97 -GFIPQSI--------DRVQVLGGVLTTPELAADAAATAQTSQF----VM
Rv3161c|M.tuberculosis_H37Rv -GFIPQSI--------DRVQVLGGVLTTPELAADAAATAQTSQF----VM
TH_2976|M.thermoresistible__bu FNIQPVAV--------NECVQYSTAVQLVG-APELNRRMVSQCIGSVGPA
MAV_5084|M.avium_104 FNIQPVAV--------NECVQYSTAVQLAG-APELNRRMVSQCIGSVGPA
Mflv_1355|M.gilvum_PYR-GCK RHFRPIAP--------DKTEVTIYCIAPKSESAQARANRIRQYEDFFNAS
MSMEG_1908|M.smegmatis_MC2_155 RHFRPIAP--------DKTEVTIYCIAPKGESAAARAHRIRQYEDFFNAS
MAB_4370c|M.abscessus_ATCC_199 RIWHPKGP--------DKMEVWAWTIVDRSMPEEVRDAQRLYNLRTFGPT
Mvan_0488|M.vanbaalenii_PYR-1 RVWHPLSH--------DRMEVLSWFLVERDAPEWLRDASQASYVNNFGPG
MMAR_0212|M.marinum_M LHQYNVFPNMTFLANADHLTIMCSRPQPEHFADPDKGEMVMFLMTRMPPD
MUL_3820|M.ulcerans_Agy99 -IYPGDRP--------GSSITVHQNSTPLDLSDESVATGAQAVFDY--AH
. .
Mb3186c|M.bovis_AF2122/97 AMINDEDRLGLEAVQVGAGSRFAERGHLSSKEWP----------------
Rv3161c|M.tuberculosis_H37Rv AMINDEDRLGLEAVQVGAGSRFAERGHLSSKEWP----------------
TH_2976|M.thermoresistible__bu GMLLADDTEMYERNQQGLEALTPEWLDIRRGLN---------REHVDDHG
MAV_5084|M.avium_104 GMLLADDTEMYERNQEGLAALSPEWLDIRRGLN---------REAIDENG
Mflv_1355|M.gilvum_PYR-GCK GMATPDDLEEFRSCQLTFRAEAAPWNDMSRGAQHWLDGPDDVARSLGLDA
MSMEG_1908|M.smegmatis_MC2_155 GMATPDDLEEFRSCQLTFRAQAAPWNDMSRGAQHWLSGPDPVAESLGMHG
MAB_4370c|M.abscessus_ATCC_199 GIFEQDDGENWSEVQSISRGFVTNSVALNYQMG---------LDSE-RED
Mvan_0488|M.vanbaalenii_PYR-1 GVFEQDDAEAWKAITESVQGPFAGEGLLNYEMG---------MDLTPLTD
MMAR_0212|M.marinum_M APHNKPTDVRMAADQAEPGIVLTQDIRVLPGVQRG-------LHQPGFTH
MUL_3820|M.ulcerans_Agy99 ATVRDEDYRLAETLQTNLESGARQRLVFGRNEP-----------------
. .
Mb3186c|M.bovis_AF2122/97 ---------------GMLAFYRNLAMALVGDHPGAS-------
Rv3161c|M.tuberculosis_H37Rv ---------------GMLAFYRNLAMALVGDHPGAS-------
TH_2976|M.thermoresistible__bu FTVGGPTDETG-----MRAFWSEYRRLMEAE------------
MAV_5084|M.avium_104 FTIGAATDETG-----MRGFWSHYQTLMSKD------------
Mflv_1355|M.gilvum_PYR-GCK VISAGVKNEDEGLYPVQHGYWLETMRAAAQKEAR---------
MSMEG_1908|M.smegmatis_MC2_155 IVSSGLRNEDEGLYPVQHGYWLETLRRAVTSNPTEH-------
MAB_4370c|M.abscessus_ATCC_199 GRHPG-LTSELYSDAAGRSFYARWRDLMNTKAWHEEHV-----
Mvan_0488|M.vanbaalenii_PYR-1 WPGPGEALPSGYAEQNQRRFWGRWLEYMGQPPAFGGRA-----
MMAR_0212|M.marinum_M LVLSGEERRIINMHRNLERYLDLPEPERMSGGGLRPGPGAPRV
MUL_3820|M.ulcerans_Agy99 ---------------GLQHRHITWAQALETPG-----------