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M. thermoresistible (build 8) TH_2845 (-)

annotation: acyl-CoA dehydrogenase
coordinates: 358303 - 359442
length: 380

aa seq not available

Operon Prediction Model: Genebank

Paralogs

species id gene e-value identity (len) annotation
M. thermoresistible (build 8) TH_2845 - - 100% (380) acyl-CoA dehydrogenase
M. thermoresistible (build 8) TH_4527 - e-116 54.74% (380) PUTATIVE acyl-CoA dehydrogenase domain protein
M. thermoresistible (build 8) TH_2583 - e-112 54.62% (379) PUTATIVE peptidase S1 and S6, chymotrypsin/Hap

Closest Orthologs (e-value cutoff: 1e-4)

species id gene e-value identity (len) annotation
M. bovis AF2122 / 97 Mb2743c fadE20 1e-110 51.97% (381) acyl-CoA dehydrogenase FADE20
M. gilvum PYR-GCK Mflv_2118 - 1e-118 55.26% (380) acyl-CoA dehydrogenase domain-containing protein
M. tuberculosis H37Rv Rv2724c fadE20 1e-111 52.49% (381) acyl-CoA dehydrogenase FADE20
M. leprae Br4923 MLBr_00737 fadE25 1e-47 31.02% (374) putative acyl-CoA dehydrogenase
M. abscessus ATCC 19977 MAB_0065c - 1e-112 51.58% (380) acyl-CoA dehydrogenase FadE
M. marinum M MMAR_1989 fadE20 1e-112 52.76% (381) acyl-CoA dehydrogenase FadE20
M. avium 104 MAV_5070 - 0.0 85.04% (381) acyl-CoA dehydrogenase
M. smegmatis MC2 155 MSMEG_5197 - 1e-116 53.68% (380) long-chain specific acyl-CoA dehydrogenase
M. ulcerans Agy99 MUL_3367 fadE20 1e-109 52.23% (381) acyl-CoA dehydrogenase FadE20
M. vanbaalenii PYR-1 Mvan_4587 - 1e-118 55.26% (380) acyl-CoA dehydrogenase domain-containing protein

CLUSTAL 2.0.9 multiple sequence alignment


TH_2845|M.thermoresistible__bu      ---------MRRSLYTADHDAYRETVREFLAREVVPFQEEWDRNRWIDRD
MAV_5070|M.avium_104                ---------MRRSLYGEDHEAYRETVREFLAREVVPFQHDWDRDRWIDRA
Mb2743c|M.bovis_AF2122/97           ---MGSATKYQRTLFEPEHELFRESYRAFLDRHVAAYHDEWEKTKIVDRG
Rv2724c|M.tuberculosis_H37Rv        ---MGSATKYQRTLFEPEHELFRESYRAFLDRHVAPYHDEWEKTKIVDRG
MMAR_1989|M.marinum_M               ---MGSAIKYQRTLFEPEHDLFRESYRGFLERHVAPYHDEWEKAKIVDRG
MUL_3367|M.ulcerans_Agy99           ---MGSAIKYQRTLFEPEHDLFRESYRGFLERHVALYHDEWEKAKIVDRG
Mflv_2118|M.gilvum_PYR-GCK          ---------MKRTIYDAEHEAFRDTVKEYIERELVPNSEKWETERIVDRS
Mvan_4587|M.vanbaalenii_PYR-1       ---------MKRTIYDAEHEAFRETVKEYIERELVPNSEKWETERIVDRS
MSMEG_5197|M.smegmatis_MC2_155      ---------MKRLIYNEEHEAFRQTVKEYIERELVPHSEKWEAERIVDRS
MAB_0065c|M.abscessus_ATCC_199      ---------MQRTIYTEDHEAFRESVKAFVQRHVDPRAETFIEQRYIDRE
MLBr_00737|M.leprae_Br4923          MVGWSGNPLFDLFKLPEEHNELRATIRALAEKEIAPHAADVDQRARFPEE
                                                     :*:  * : :    :.:            . . 

TH_2845|M.thermoresistible__bu      VFARAAKAGIYALQIDEKYGGAGEPDYRYRMVVCEEIARITALSFGLTVS
MAV_5070|M.avium_104                VFPRAAKAGIYALQVGEEYGGAGESDYRYRMVVCEEVSRVTALSFGLTIS
Mb2743c|M.bovis_AF2122/97           VWLEAGKQGFLGMAVPEEYGGGGNADFRYNTVITEETCAG--RYSGIGFG
Rv2724c|M.tuberculosis_H37Rv        VWLEAGKQGFLGMAVPEEYGGGGNADFRYNTVITEETCAG--RYSGIGFG
MMAR_1989|M.marinum_M               VWLEAGKQGFLGMAVPEEYGGGGNPDFRYNTIITEETSAG--RYSGIGFG
MUL_3367|M.ulcerans_Agy99           VWLEAGKQGFLGMAVPEEYGGGGNPDFRYNTIITEETSAG--RYSGIGFG
Mflv_2118|M.gilvum_PYR-GCK          AYTAAGKYGLIGFNMPEEFGGGGTDDFRFNAIIDEEIAKA--GVHGPALS
Mvan_4587|M.vanbaalenii_PYR-1       AYTAAGKYGLIGFNMPEEYGGGGSEDFRFNAIIDEEMAKS--GVHGPALS
MSMEG_5197|M.smegmatis_MC2_155      AYTAAGKYGLIGFNMPEEFGGGGSDDFRFNAIIDEEIAKS--GVHGPALS
MAB_0065c|M.abscessus_ATCC_199      LWEEAGKQGYLGLDVPEEFGGSSAGDYRYNAVLQEELARSS-AALASSMS
MLBr_00737|M.leprae_Br4923          ALAALNASGFNAIHVPEEYGGQG-ADSVAACIVIEEVARVD--ASASLIP
                                            *  .: : *::** .  *     :: ** .       .  . 

TH_2845|M.thermoresistible__bu      LQDDLVLHYLLDLTTEEQKQRWLPGFASGELIGALAMTEPDAGSDLRGIR
MAV_5070|M.avium_104                LQDDLVLHYLLDLTNDEQKQRWLPGFAAGELIGALAMTEPGAGSDLRGMR
Mb2743c|M.bovis_AF2122/97           LHNDIVAPYLLALATEEQKRRWFPNFCTGELTTAIAMTEPGTGSDLQGIT
Rv2724c|M.tuberculosis_H37Rv        LHNDIVAPYLLALATEEQKRRWFPNFCTGELITAIAMTEPGTGSDLQGIT
MMAR_1989|M.marinum_M               LHNDIVAPYLLALATEEQKQRWLPKFCTGEFITAIAMTEPGTGSDLQGIK
MUL_3367|M.ulcerans_Agy99           LHNEIVAPYLLALATEEQKQRRLPKFCTGEFITAIAMTEPGTGSDLQGIK
Mflv_2118|M.gilvum_PYR-GCK          LHNDVVGPYFKDLTNDEQKKRWLPGVTSGETIIAVAMTEPGAGSDLAGIR
Mvan_4587|M.vanbaalenii_PYR-1       LHNDVVGPYFKDLTNDEQKKRWLPGIASGETIIAVAMTEPGAGSDLAGIR
MSMEG_5197|M.smegmatis_MC2_155      LHNDVVGPYFKELANDEQRRRWLPGITSGELIIAIAMTEPGAGSDLAGIR
MAB_0065c|M.abscessus_ATCC_199      IHFDIVAPYLVELTTDEQKQRWLPKFCSGEMITAIGMTEPSGGSDLAALK
MLBr_00737|M.leprae_Br4923          AVNKLGTMGLILRGSEELKKQVLPSLAAEGAMASYALSEREAGSDAASMR
                                       .:    :    .:* ::: :* . :     : .::*   ***  .: 

TH_2845|M.thermoresistible__bu      TTAHRDGDRWILNGQKTFISSGIMADVVVVAARTGER-----HSLFVVER
MAV_5070|M.avium_104                TTAHRDGDQWILNGQKTFISSGIMADVVVVAARTDPNGGSGAFSLFVVER
Mb2743c|M.bovis_AF2122/97           TRAVKHGDHYVLNGSKTFITNGINSDLVIVVAQTDPEKGAQGFSLLVVER
Rv2724c|M.tuberculosis_H37Rv        TRAVKHGDHYVLNGSKTFITNGINSDLVIVVAQTDPEKGAQGFSLLVVER
MMAR_1989|M.marinum_M               TRAVKQGDHYLLNGSKTFITNGINADLVIVVAQTDPEKGAQGFSLLVVER
MUL_3367|M.ulcerans_Agy99           TRAVKQGDHYLLNGSKTFITNGINADLVIVVAQTDPEKGAQGFSLLVVER
Mflv_2118|M.gilvum_PYR-GCK          TSAVRDGDDWIINGSKTFISSGINCDLCVVVARTDPEAGHKGFSLFVVER
Mvan_4587|M.vanbaalenii_PYR-1       TSAVRDGDDWIINGSKTFISSGINCDLCVVVARTDPEAGHKGFSLFVVER
MSMEG_5197|M.smegmatis_MC2_155      TSAVRDGDDWIINGSKTFISSGINCDLCVVVARTDPEAGHKGFSLFVVER
MAB_0065c|M.abscessus_ATCC_199      TTAVKDGDDWVINGSKTFITNGARADLVVVAARTAPELKAKGITLFAVEE
MLBr_00737|M.leprae_Br4923          TRAKADGDDWILNGFKCWITNGGKSTWYTVMAVTDPDKGANGISAFIVHK
                                    * *  .** :::** * :*:.*  .    * * *         : : *..

TH_2845|M.thermoresistible__bu      DTPGFERGRKLDKIGLPAQDTAELFFRDAVVPAENLLGEEGRGLAYLMSH
MAV_5070|M.avium_104                DTPGFERGRKLDKIGLPAQDTAELYFRDAQVPGANLLGTVGEGLRYLMSH
Mb2743c|M.bovis_AF2122/97           GMAGFERGRQLDKIGLDAQDTAELSFTDVAVPAENLLGQEGMGFIYLMQN
Rv2724c|M.tuberculosis_H37Rv        GMAGFERGRQLDKIGLDAQDTAELSFTDVAVPAENLLGQEGMGFIYLMQN
MMAR_1989|M.marinum_M               GMEGFERGRHLDKIGLDAQDTAELSFSDVQVPVENLLGQEGMGFIYLMQN
MUL_3367|M.ulcerans_Agy99           GMEGFERGRHLDKIGLDAQDTAELSFSDVQVPVENLLGQEGMGFIYLMQN
Mflv_2118|M.gilvum_PYR-GCK          DMEGFTRGRKLDKMGLHSQDTSELHFENVRVPNANLLGKEGRGFYHLMTN
Mvan_4587|M.vanbaalenii_PYR-1       GMEGFTRGRKLDKMGLHSQDTSELHFENVRVPNANLLGKEGRGFYHLMTN
MSMEG_5197|M.smegmatis_MC2_155      GMEGFTRGRKLDKMGLHSQDTSELHFENVRVPHANLLGKEGRGFYHLMTN
MAB_0065c|M.abscessus_ATCC_199      GMPGFERGRKLDKVGQPEADTAELFFTDVRVPAENVIGEVNQGFISMMQR
MLBr_00737|M.leprae_Br4923          DDEGFSIGPKEKKLGIKGSPTTELYFDKCRIPGDRIIGEPGTGFKTALAT
                                    .  **  * : .*:*     *:** * .  :*  .::*  . *:   :  

TH_2845|M.thermoresistible__bu      LPRERLGVTAKAMATTRAIFDMTVEYCRQRKAFGAPLIDKQHVRFELADM
MAV_5070|M.avium_104                LPRERLGVTAKSLATTRAIFDTTVEYCQQRMAFGGPLTDKQHIRFELAEM
Mb2743c|M.bovis_AF2122/97           LPQERISIAIMAAAGMESVLEQTLQYAKERKAFGRSIGSFQNSRFLLAEL
Rv2724c|M.tuberculosis_H37Rv        LPQERISIAIMAAAGMESVLEQTLQYAKERKAFGRSIGSFQNSRFLLAEL
MMAR_1989|M.marinum_M               LPQERISIAIMAAAGMESVLDQTLQYTKERKAFGRSIGNFQNSRFVLAEL
MUL_3367|M.ulcerans_Agy99           LPQERISIAIMAAAGMESVLDQTLQYTKERKAFGRSIGNFQNSRFVLAEL
Mflv_2118|M.gilvum_PYR-GCK          LPSERLSIAISAIAGARAVFDETLQYSKDRKAFGQSIGSFQHNRFLLAEM
Mvan_4587|M.vanbaalenii_PYR-1       LPSERLSIAISAIAGARAVFQETLQYAKDRKAFGQPIGSFQHNRFLLAEM
MSMEG_5197|M.smegmatis_MC2_155      LPSERLSIAISAIAGARAVFDETLQYCKDRKAFGQPIGSFQHNRFLLAEM
MAB_0065c|M.abscessus_ATCC_199      LPQERMGCAVANIAHAVAVLEETVEYAKERKAFGQQIGSLQYNKFLIAEL
MLBr_00737|M.leprae_Br4923          LDHTRPTIGAQAVGIAQGALDAAIVYTKDRKQFGESISTFQSIQFMLADM
                                    *   *        .   . :: :: * ::*  **  :   *  :* :*::

TH_2845|M.thermoresistible__bu      ATEIDVAQAYTDQSVLAYNAGE-LTPVDAAKGKWFVSELQKRVIDRCLQL
MAV_5070|M.avium_104                ATEIDVAEAYVDKSVLAYNAGE-LTAVDAAKGKWYLSELQKRVIDRCLQL
Mb2743c|M.bovis_AF2122/97           ATEATVVRIMVDEFIKLHLAGK-LTAEQAAMAKWYATEKQVYLNDRCLQL
Rv2724c|M.tuberculosis_H37Rv        ATEATVVRIMVDEFIKLHLAGK-LTAEQAAMAKWYATEKQVYLNDRCLQL
MMAR_1989|M.marinum_M               ATEATMVRIMVDEFIELHLDGK-LTAEQAAMAKWYSTEKQVSLNDRCLQL
MUL_3367|M.ulcerans_Agy99           ATEATMVRIMVDESIELHLDGK-LTAEQAAMAKWYSTEKQVSLNDRCLQL
Mflv_2118|M.gilvum_PYR-GCK          ETELEVTETYIDRCLQGVVDGE-LTAVEAAKAKWWATEVAKKVVDQCVQL
Mvan_4587|M.vanbaalenii_PYR-1       ETELEVTENYIDRCLQGVVDGE-LTAVEAAKAKWWATETAKKVVDQCVQL
MSMEG_5197|M.smegmatis_MC2_155      ETELEVTENYIDRCLQGVVDGE-LTAVEAAKAKWWATETAKKIVDNCVQL
MAB_0065c|M.abscessus_ATCC_199      VTKLEAAQVYVDQAVLAHSKGE-LTAIDAAKAKWWSSQVQNEVIDACVQL
MLBr_00737|M.leprae_Br4923          AMKVEAARLIVYAAAARAERGEPDLGFISAASKCFASDIAMEVTTDAVQL
                                      :   ..            *:      :* .* : ::    :   .:**

TH_2845|M.thermoresistible__bu      HGGYGYMTEYPVARAYLDTRVQTIYGGTTEIMKEIIGRELAAGR
MAV_5070|M.avium_104                HGGYGYMTEYPVARAYLDTRIQTIYGGTTEIMKEIIGRDIAKS-
Mb2743c|M.bovis_AF2122/97           HGGYGYMREYPVARAYLDSRVQTIYGGTTEIMKEIIGRGLGV--
Rv2724c|M.tuberculosis_H37Rv        HGGYGYMREYPVARAYLDSRVQTIYGGTTEIMKEIIGRGLGV--
MMAR_1989|M.marinum_M               HGGYGYMREYPVARAYLDSRVQTIYGGTTEIMKEIIGRSLGI--
MUL_3367|M.ulcerans_Agy99           HGGYGYMREYPVARAYLDSRVQTIYGGTTEIMKEIIGRSLGI--
Mflv_2118|M.gilvum_PYR-GCK          HGGYGYMLEYRVARAYVDGRIQTIFGGTTEIMKEIIGRELGV--
Mvan_4587|M.vanbaalenii_PYR-1       HGGYGYMLEYRVARAYVDGRIQTIFGGTTEIMKEIIGRELGV--
MSMEG_5197|M.smegmatis_MC2_155      HGGYGYMMEYRVARAYVDGRIQTIFGGTTEIMKEIIGRDLGV--
MAB_0065c|M.abscessus_ATCC_199      HGGYGYMKEYRVARAWMDARVTKIWAGSNEIMKELIGRDLGF--
MLBr_00737|M.leprae_Br4923          FGGAGYTSDFPVERFMRDAKITQIYEGTNQIQRVVMSRALLR--
                                    .** **  :: * *   * ::  *: *:.:* : ::.* :

species	id	gene	e-value	identity (len)	annotation
M. thermoresistible (build 8)	TH_2845	-	-	100% (380)	acyl-CoA dehydrogenase
M. thermoresistible (build 8)	TH_4527	-	e-116	54.74% (380)	PUTATIVE acyl-CoA dehydrogenase domain protein
M. thermoresistible (build 8)	TH_2583	-	e-112	54.62% (379)	PUTATIVE peptidase S1 and S6, chymotrypsin/Hap