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MRRSLYGEDHEAYRETVREFLAREVVPFQHDWDRDRWIDRAVFPRAAKAGIYALQVGEEYGGAGESDYRY RMVVCEEVSRVTALSFGLTISLQDDLVLHYLLDLTNDEQKQRWLPGFAAGELIGALAMTEPGAGSDLRGM RTTAHRDGDQWILNGQKTFISSGIMADVVVVAARTDPNGGSGAFSLFVVERDTPGFERGRKLDKIGLPAQ DTAELYFRDAQVPGANLLGTVGEGLRYLMSHLPRERLGVTAKSLATTRAIFDTTVEYCQQRMAFGGPLTD KQHIRFELAEMATEIDVAEAYVDKSVLAYNAGELTAVDAAKGKWYLSELQKRVIDRCLQLHGGYGYMTEY PVARAYLDTRIQTIYGGTTEIMKEIIGRDIAKS
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. avium 104 | MAV_5070 | - | - | 100% (383) | acyl-CoA dehydrogenase |
| M. avium 104 | MAV_1883 | - | e-117 | 54.74% (380) | putative acyl-CoA dehydrogenase |
| M. avium 104 | MAV_2600 | - | e-117 | 55.00% (380) | acyl-CoA dehydrogenase |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb2743c | fadE20 | 1e-111 | 52.23% (381) | acyl-CoA dehydrogenase FADE20 |
| M. gilvum PYR-GCK | Mflv_2118 | - | 1e-124 | 55.53% (380) | acyl-CoA dehydrogenase domain-containing protein |
| M. tuberculosis H37Rv | Rv2724c | fadE20 | 1e-112 | 52.76% (381) | acyl-CoA dehydrogenase FADE20 |
| M. leprae Br4923 | MLBr_00737 | fadE25 | 6e-53 | 34.03% (382) | putative acyl-CoA dehydrogenase |
| M. abscessus ATCC 19977 | MAB_3040c | - | 1e-114 | 52.24% (379) | acyl-CoA dehydrogenase |
| M. marinum M | MMAR_1989 | fadE20 | 1e-113 | 53.02% (381) | acyl-CoA dehydrogenase FadE20 |
| M. smegmatis MC2 155 | MSMEG_5197 | - | 1e-124 | 55.26% (380) | long-chain specific acyl-CoA dehydrogenase |
| M. thermoresistible (build 8) | TH_2845 | - | 0.0 | 85.04% (381) | PUTATIVE acyl-CoA dehydrogenase |
| M. ulcerans Agy99 | MUL_3367 | fadE20 | 1e-110 | 52.49% (381) | acyl-CoA dehydrogenase FadE20 |
| M. vanbaalenii PYR-1 | Mvan_4587 | - | 1e-124 | 56.05% (380) | acyl-CoA dehydrogenase domain-containing protein |
CLUSTAL 2.0.9 multiple sequence alignment
MAV_5070|M.avium_104 ---------MRRSLYGEDHEAYRETVREFLAREVVPFQHDWDRDRWIDRA
TH_2845|M.thermoresistible__bu ---------MRRSLYTADHDAYRETVREFLAREVVPFQEEWDRNRWIDRD
MMAR_1989|M.marinum_M ---MGSAIKYQRTLFEPEHDLFRESYRGFLERHVAPYHDEWEKAKIVDRG
MUL_3367|M.ulcerans_Agy99 ---MGSAIKYQRTLFEPEHDLFRESYRGFLERHVALYHDEWEKAKIVDRG
Mb2743c|M.bovis_AF2122/97 ---MGSATKYQRTLFEPEHELFRESYRAFLDRHVAAYHDEWEKTKIVDRG
Rv2724c|M.tuberculosis_H37Rv ---MGSATKYQRTLFEPEHELFRESYRAFLDRHVAPYHDEWEKTKIVDRG
MAB_3040c|M.abscessus_ATCC_199 ---MAGAVKFKRTIFEPEHELFRESFKTFLDRHAEPYKEEWEKNKIVDRA
Mflv_2118|M.gilvum_PYR-GCK ---------MKRTIYDAEHEAFRDTVKEYIERELVPNSEKWETERIVDRS
Mvan_4587|M.vanbaalenii_PYR-1 ---------MKRTIYDAEHEAFRETVKEYIERELVPNSEKWETERIVDRS
MSMEG_5197|M.smegmatis_MC2_155 ---------MKRLIYNEEHEAFRQTVKEYIERELVPHSEKWEAERIVDRS
MLBr_00737|M.leprae_Br4923 MVGWSGNPLFDLFKLPEEHNELRATIRALAEKEIAPHAADVDQRARFPEE
:*: * : : :. . : . .
MAV_5070|M.avium_104 VFPRAAKAGIYALQVGEEYGGAGESDYRYRMVVCEEVSRVTALSFGLTIS
TH_2845|M.thermoresistible__bu VFARAAKAGIYALQIDEKYGGAGEPDYRYRMVVCEEIARITALSFGLTVS
MMAR_1989|M.marinum_M VWLEAGKQGFLGMAVPEEYGGGGNPDFRYNTIITEETS--AGRYSGIGFG
MUL_3367|M.ulcerans_Agy99 VWLEAGKQGFLGMAVPEEYGGGGNPDFRYNTIITEETS--AGRYSGIGFG
Mb2743c|M.bovis_AF2122/97 VWLEAGKQGFLGMAVPEEYGGGGNADFRYNTVITEETC--AGRYSGIGFG
Rv2724c|M.tuberculosis_H37Rv VWLEAGKQGFLGMAVPEEYGGGGNADFRYNTVITEETC--AGRYSGIGFG
MAB_3040c|M.abscessus_ATCC_199 LWVEAGKQGFLGTDMPEEFGGGGLIDFRYNTIITEEVT--KGRHTGVGFS
Mflv_2118|M.gilvum_PYR-GCK AYTAAGKYGLIGFNMPEEFGGGGTDDFRFNAIIDEEIA--KAGVHGPALS
Mvan_4587|M.vanbaalenii_PYR-1 AYTAAGKYGLIGFNMPEEYGGGGSEDFRFNAIIDEEMA--KSGVHGPALS
MSMEG_5197|M.smegmatis_MC2_155 AYTAAGKYGLIGFNMPEEFGGGGSDDFRFNAIIDEEIA--KSGVHGPALS
MLBr_00737|M.leprae_Br4923 ALAALNASGFNAIHVPEEYGGQGADSVAACIVIEEVAR---VDASASLIP
*: . : *::** * . :: * . .
MAV_5070|M.avium_104 LQDDLVLHYLLDLTNDEQKQRWLPGFAAGELIGALAMTEPGAGSDLRGMR
TH_2845|M.thermoresistible__bu LQDDLVLHYLLDLTTEEQKQRWLPGFASGELIGALAMTEPDAGSDLRGIR
MMAR_1989|M.marinum_M LHNDIVAPYLLALATEEQKQRWLPKFCTGEFITAIAMTEPGTGSDLQGIK
MUL_3367|M.ulcerans_Agy99 LHNEIVAPYLLALATEEQKQRRLPKFCTGEFITAIAMTEPGTGSDLQGIK
Mb2743c|M.bovis_AF2122/97 LHNDIVAPYLLALATEEQKRRWFPNFCTGELTTAIAMTEPGTGSDLQGIT
Rv2724c|M.tuberculosis_H37Rv LHNDIVAPYLLALATEEQKRRWFPNFCTGELITAIAMTEPGTGSDLQGIT
MAB_3040c|M.abscessus_ATCC_199 LHNDVAGPYFRDLANDEQKARWFPGFCSGELISAIAMTEPGTGSDLQGIK
Mflv_2118|M.gilvum_PYR-GCK LHNDVVGPYFKDLTNDEQKKRWLPGVTSGETIIAVAMTEPGAGSDLAGIR
Mvan_4587|M.vanbaalenii_PYR-1 LHNDVVGPYFKDLTNDEQKKRWLPGIASGETIIAVAMTEPGAGSDLAGIR
MSMEG_5197|M.smegmatis_MC2_155 LHNDVVGPYFKELANDEQRRRWLPGITSGELIIAIAMTEPGAGSDLAGIR
MLBr_00737|M.leprae_Br4923 AVNKLGTMGLILRGSEELKKQVLPSLAAEGAMASYALSEREAGSDAASMR
:.: : .:* : : :* . : : *::* :*** .:
MAV_5070|M.avium_104 TTAHRDGDQWILNGQKTFISSGIMADVVVVAARTDPNGGSGAFSLFVVER
TH_2845|M.thermoresistible__bu TTAHRDGDRWILNGQKTFISSGIMADVVVVAARTGER-----HSLFVVER
MMAR_1989|M.marinum_M TRAVKQGDHYLLNGSKTFITNGINADLVIVVAQTDPEKGAQGFSLLVVER
MUL_3367|M.ulcerans_Agy99 TRAVKQGDHYLLNGSKTFITNGINADLVIVVAQTDPEKGAQGFSLLVVER
Mb2743c|M.bovis_AF2122/97 TRAVKHGDHYVLNGSKTFITNGINSDLVIVVAQTDPEKGAQGFSLLVVER
Rv2724c|M.tuberculosis_H37Rv TRAVKHGDHYVLNGSKTFITNGINSDLVIVVAQTDPEKGAQGFSLLVVER
MAB_3040c|M.abscessus_ATCC_199 TRAVKDGDHYILNGAKTFITNGINADLVIVVAQTDPEKGALGFSLIVVER
Mflv_2118|M.gilvum_PYR-GCK TSAVRDGDDWIINGSKTFISSGINCDLCVVVARTDPEAGHKGFSLFVVER
Mvan_4587|M.vanbaalenii_PYR-1 TSAVRDGDDWIINGSKTFISSGINCDLCVVVARTDPEAGHKGFSLFVVER
MSMEG_5197|M.smegmatis_MC2_155 TSAVRDGDDWIINGSKTFISSGINCDLCVVVARTDPEAGHKGFSLFVVER
MLBr_00737|M.leprae_Br4923 TRAKADGDDWILNGFKCWITNGGKSTWYTVMAVTDPDKGANGISAFIVHK
* * .** :::** * :*:.* . * * *. * ::*.:
MAV_5070|M.avium_104 DTPGFERGRKLDKIGLPAQDTAELYFRDAQVPGANLLGTVGEGLRYLMSH
TH_2845|M.thermoresistible__bu DTPGFERGRKLDKIGLPAQDTAELFFRDAVVPAENLLGEEGRGLAYLMSH
MMAR_1989|M.marinum_M GMEGFERGRHLDKIGLDAQDTAELSFSDVQVPVENLLGQEGMGFIYLMQN
MUL_3367|M.ulcerans_Agy99 GMEGFERGRHLDKIGLDAQDTAELSFSDVQVPVENLLGQEGMGFIYLMQN
Mb2743c|M.bovis_AF2122/97 GMAGFERGRQLDKIGLDAQDTAELSFTDVAVPAENLLGQEGMGFIYLMQN
Rv2724c|M.tuberculosis_H37Rv GMAGFERGRQLDKIGLDAQDTAELSFTDVAVPAENLLGQEGMGFIYLMQN
MAB_3040c|M.abscessus_ATCC_199 GMEGFERGRKLDKVGLDAQDTAELSFTDVRVPAANLLGEEGQGFIYLMKN
Mflv_2118|M.gilvum_PYR-GCK DMEGFTRGRKLDKMGLHSQDTSELHFENVRVPNANLLGKEGRGFYHLMTN
Mvan_4587|M.vanbaalenii_PYR-1 GMEGFTRGRKLDKMGLHSQDTSELHFENVRVPNANLLGKEGRGFYHLMTN
MSMEG_5197|M.smegmatis_MC2_155 GMEGFTRGRKLDKMGLHSQDTSELHFENVRVPHANLLGKEGRGFYHLMTN
MLBr_00737|M.leprae_Br4923 DDEGFSIGPKEKKLGIKGSPTTELYFDKCRIPGDRIIGEPGTGFKTALAT
. ** * : .*:*: .. *:** * . :* .::* * *: :
MAV_5070|M.avium_104 LPRERLGVTAKSLATTRAIFDTTVEYCQQRMAFGGPLTDKQHIRFELAEM
TH_2845|M.thermoresistible__bu LPRERLGVTAKAMATTRAIFDMTVEYCRQRKAFGAPLIDKQHVRFELADM
MMAR_1989|M.marinum_M LPQERISIAIMAAAGMESVLDQTLQYTKERKAFGRSIGNFQNSRFVLAEL
MUL_3367|M.ulcerans_Agy99 LPQERISIAIMAAAGMESVLDQTLQYTKERKAFGRSIGNFQNSRFVLAEL
Mb2743c|M.bovis_AF2122/97 LPQERISIAIMAAAGMESVLEQTLQYAKERKAFGRSIGSFQNSRFLLAEL
Rv2724c|M.tuberculosis_H37Rv LPQERISIAIMAAAGMESVLEQTLQYAKERKAFGRSIGSFQNSRFLLAEL
MAB_3040c|M.abscessus_ATCC_199 LPQERMSIAVMAAAAMESVLEETIAYTTERKAFGKPIKSFQNSRFLLAEL
Mflv_2118|M.gilvum_PYR-GCK LPSERLSIAISAIAGARAVFDETLQYSKDRKAFGQSIGSFQHNRFLLAEM
Mvan_4587|M.vanbaalenii_PYR-1 LPSERLSIAISAIAGARAVFQETLQYAKDRKAFGQPIGSFQHNRFLLAEM
MSMEG_5197|M.smegmatis_MC2_155 LPSERLSIAISAIAGARAVFDETLQYCKDRKAFGQPIGSFQHNRFLLAEM
MLBr_00737|M.leprae_Br4923 LDHTRPTIGAQAVGIAQGALDAAIVYTKDRKQFGESISTFQSIQFMLADM
* * : : . .. :: :: * :* ** .: * :* **::
MAV_5070|M.avium_104 ATEIDVAEAYVDKSVLAYNAGE-LTAVDAAKGKWYLSELQKRVIDRCLQL
TH_2845|M.thermoresistible__bu ATEIDVAQAYTDQSVLAYNAGE-LTPVDAAKGKWFVSELQKRVIDRCLQL
MMAR_1989|M.marinum_M ATEATMVRIMVDEFIELHLDGK-LTAEQAAMAKWYSTEKQVSLNDRCLQL
MUL_3367|M.ulcerans_Agy99 ATEATMVRIMVDESIELHLDGK-LTAEQAAMAKWYSTEKQVSLNDRCLQL
Mb2743c|M.bovis_AF2122/97 ATEATVVRIMVDEFIKLHLAGK-LTAEQAAMAKWYATEKQVYLNDRCLQL
Rv2724c|M.tuberculosis_H37Rv ATEATVVRIMVDEFIKLHLAGK-LTAEQAAMAKWYATEKQVYLNDRCLQL
MAB_3040c|M.abscessus_ATCC_199 ATDATVIRVMVDEFISLLNKEE-LSVEQAAMAKWYSTEKQVHLIDRCLQL
Mflv_2118|M.gilvum_PYR-GCK ETELEVTETYIDRCLQGVVDGE-LTAVEAAKAKWWATEVAKKVVDQCVQL
Mvan_4587|M.vanbaalenii_PYR-1 ETELEVTENYIDRCLQGVVDGE-LTAVEAAKAKWWATETAKKVVDQCVQL
MSMEG_5197|M.smegmatis_MC2_155 ETELEVTENYIDRCLQGVVDGE-LTAVEAAKAKWWATETAKKIVDNCVQL
MLBr_00737|M.leprae_Br4923 AMKVEAARLIVYAAAARAERGEPDLGFISAASKCFASDIAMEVTTDAVQL
. . : :* .* : :: : .:**
MAV_5070|M.avium_104 HGGYGYMTEYPVARAYLDTRIQTIYGGTTEIMKEIIGRDIAKS-
TH_2845|M.thermoresistible__bu HGGYGYMTEYPVARAYLDTRVQTIYGGTTEIMKEIIGRELAAGR
MMAR_1989|M.marinum_M HGGYGYMREYPVARAYLDSRVQTIYGGTTEIMKEIIGRSLGI--
MUL_3367|M.ulcerans_Agy99 HGGYGYMREYPVARAYLDSRVQTIYGGTTEIMKEIIGRSLGI--
Mb2743c|M.bovis_AF2122/97 HGGYGYMREYPVARAYLDSRVQTIYGGTTEIMKEIIGRGLGV--
Rv2724c|M.tuberculosis_H37Rv HGGYGYMREYPVARAYLDSRVQTIYGGTTEIMKEIIGRGLGV--
MAB_3040c|M.abscessus_ATCC_199 HGGYGFMREYPVARAYMDSRIQTIYGGTTEIMKEIIGRSL----
Mflv_2118|M.gilvum_PYR-GCK HGGYGYMLEYRVARAYVDGRIQTIFGGTTEIMKEIIGRELGV--
Mvan_4587|M.vanbaalenii_PYR-1 HGGYGYMLEYRVARAYVDGRIQTIFGGTTEIMKEIIGRELGV--
MSMEG_5197|M.smegmatis_MC2_155 HGGYGYMMEYRVARAYVDGRIQTIFGGTTEIMKEIIGRDLGV--
MLBr_00737|M.leprae_Br4923 FGGAGYTSDFPVERFMRDAKITQIYEGTNQIQRVVMSRALLR--
.** *: :: * * * :: *: **.:* : ::.* :