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M. gilvum PYR-GCK Mflv_2118 (-)

annotation: acyl-CoA dehydrogenase domain-containing protein
coordinates: 2196479 - 2197621
length: 380

MKRTIYDAEHEAFRDTVKEYIERELVPNSEKWETERIVDRSAYTAAGKYGLIGFNMPEEFGGGGTDDFRF
NAIIDEEIAKAGVHGPALSLHNDVVGPYFKDLTNDEQKKRWLPGVTSGETIIAVAMTEPGAGSDLAGIRT
SAVRDGDDWIINGSKTFISSGINCDLCVVVARTDPEAGHKGFSLFVVERDMEGFTRGRKLDKMGLHSQDT
SELHFENVRVPNANLLGKEGRGFYHLMTNLPSERLSIAISAIAGARAVFDETLQYSKDRKAFGQSIGSFQ
HNRFLLAEMETELEVTETYIDRCLQGVVDGELTAVEAAKAKWWATEVAKKVVDQCVQLHGGYGYMLEYRV
ARAYVDGRIQTIFGGTTEIMKEIIGRELGV

Operon Prediction Model: Genebank

Paralogs

species id gene e-value identity (len) annotation
M. gilvum PYR-GCK Mflv_2118 - - 100% (380) acyl-CoA dehydrogenase domain-containing protein
M. gilvum PYR-GCK Mflv_4558 - e-112 51.05% (380) acyl-CoA dehydrogenase domain-containing protein
M. gilvum PYR-GCK Mflv_2446 - e-103 46.37% (386) acyl-CoA dehydrogenase domain-containing protein

Closest Orthologs (e-value cutoff: 1e-4)

species id gene e-value identity (len) annotation
M. bovis AF2122 / 97 Mb2743c fadE20 1e-127 56.99% (379) acyl-CoA dehydrogenase FADE20
M. tuberculosis H37Rv Rv2724c fadE20 1e-128 57.52% (379) acyl-CoA dehydrogenase FADE20
M. leprae Br4923 MLBr_00737 fadE25 2e-56 33.33% (372) putative acyl-CoA dehydrogenase
M. abscessus ATCC 19977 MAB_3040c - 1e-133 60.21% (377) acyl-CoA dehydrogenase
M. marinum M MMAR_1989 fadE20 1e-130 57.52% (379) acyl-CoA dehydrogenase FadE20
M. avium 104 MAV_1883 - 0.0 80.26% (380) putative acyl-CoA dehydrogenase
M. smegmatis MC2 155 MSMEG_5197 - 0.0 93.16% (380) long-chain specific acyl-CoA dehydrogenase
M. thermoresistible (build 8) TH_4527 - 0.0 87.11% (380) PUTATIVE acyl-CoA dehydrogenase domain protein
M. ulcerans Agy99 MUL_3367 fadE20 1e-127 56.73% (379) acyl-CoA dehydrogenase FadE20
M. vanbaalenii PYR-1 Mvan_4587 - 0.0 96.32% (380) acyl-CoA dehydrogenase domain-containing protein

CLUSTAL 2.0.9 multiple sequence alignment


Mb2743c|M.bovis_AF2122/97           ---MGSATKYQRTLFEPEHELFRESYRAFLDRHVAAYHDEWEKTKIVDRG
Rv2724c|M.tuberculosis_H37Rv        ---MGSATKYQRTLFEPEHELFRESYRAFLDRHVAPYHDEWEKTKIVDRG
MMAR_1989|M.marinum_M               ---MGSAIKYQRTLFEPEHDLFRESYRGFLERHVAPYHDEWEKAKIVDRG
MUL_3367|M.ulcerans_Agy99           ---MGSAIKYQRTLFEPEHDLFRESYRGFLERHVALYHDEWEKAKIVDRG
MAB_3040c|M.abscessus_ATCC_199      ---MAGAVKFKRTIFEPEHELFRESFKTFLDRHAEPYKEEWEKNKIVDRA
Mflv_2118|M.gilvum_PYR-GCK          ---------MKRTIYDAEHEAFRDTVKEYIERELVPNSEKWETERIVDRS
Mvan_4587|M.vanbaalenii_PYR-1       ---------MKRTIYDAEHEAFRETVKEYIERELVPNSEKWETERIVDRS
MSMEG_5197|M.smegmatis_MC2_155      ---------MKRLIYNEEHEAFRQTVKEYIERELVPHSEKWEAERIVDRS
TH_4527|M.thermoresistible__bu      ---------MKRTVYEPEHEAFRETVREYIERELVPHAEKWETERIVDRS
MAV_1883|M.avium_104                ---------MKRLVLESEHEAFRETVRQFIDQELVPNAEKWETNRLVDRS
MLBr_00737|M.leprae_Br4923          MVGWSGNPLFDLFKLPEEHNELRATIRALAEKEIAPHAADVDQRARFPEE
                                              .      **: :* : :   ::.      . :    . . 

Mb2743c|M.bovis_AF2122/97           VWLEAGKQGFLGMAVPEEYGGGGNADFRYNTVITEETCAGRYSGIGFGLH
Rv2724c|M.tuberculosis_H37Rv        VWLEAGKQGFLGMAVPEEYGGGGNADFRYNTVITEETCAGRYSGIGFGLH
MMAR_1989|M.marinum_M               VWLEAGKQGFLGMAVPEEYGGGGNPDFRYNTIITEETSAGRYSGIGFGLH
MUL_3367|M.ulcerans_Agy99           VWLEAGKQGFLGMAVPEEYGGGGNPDFRYNTIITEETSAGRYSGIGFGLH
MAB_3040c|M.abscessus_ATCC_199      LWVEAGKQGFLGTDMPEEFGGGGLIDFRYNTIITEEVTKGRHTGVGFSLH
Mflv_2118|M.gilvum_PYR-GCK          AYTAAGKYGLIGFNMPEEFGGGGTDDFRFNAIIDEEIAKAGVHGPALSLH
Mvan_4587|M.vanbaalenii_PYR-1       AYTAAGKYGLIGFNMPEEYGGGGSEDFRFNAIIDEEMAKSGVHGPALSLH
MSMEG_5197|M.smegmatis_MC2_155      AYTAAGKYGLIGFNMPEEFGGGGSDDFRFNAIIDEEIAKSGVHGPALSLH
TH_4527|M.thermoresistible__bu      AYVAAGKYGLIGFNMPEKYGGGGTDDFRFNAVIDEEMAKAGVPGPALSLH
MAV_1883|M.avium_104                AWVAAGKYGLIGFNMPEQYGGSGVDDFRFNAVIDEEIARYGGPAPALSLQ
MLBr_00737|M.leprae_Br4923          ALAALNASGFNAIHVPEEYGGQG-ADSVAACIVIEEVARVDASASLIPAV
                                         .  *: .  :**::** *  *     :: **       .  :   

Mb2743c|M.bovis_AF2122/97           NDIVAPYLLALATEEQKRRWFPNFCTGELTTAIAMTEPGTGSDLQGITTR
Rv2724c|M.tuberculosis_H37Rv        NDIVAPYLLALATEEQKRRWFPNFCTGELITAIAMTEPGTGSDLQGITTR
MMAR_1989|M.marinum_M               NDIVAPYLLALATEEQKQRWLPKFCTGEFITAIAMTEPGTGSDLQGIKTR
MUL_3367|M.ulcerans_Agy99           NEIVAPYLLALATEEQKQRRLPKFCTGEFITAIAMTEPGTGSDLQGIKTR
MAB_3040c|M.abscessus_ATCC_199      NDVAGPYFRDLANDEQKARWFPGFCSGELISAIAMTEPGTGSDLQGIKTR
Mflv_2118|M.gilvum_PYR-GCK          NDVVGPYFKDLTNDEQKKRWLPGVTSGETIIAVAMTEPGAGSDLAGIRTS
Mvan_4587|M.vanbaalenii_PYR-1       NDVVGPYFKDLTNDEQKKRWLPGIASGETIIAVAMTEPGAGSDLAGIRTS
MSMEG_5197|M.smegmatis_MC2_155      NDVVGPYFKELANDEQRRRWLPGITSGELIIAIAMTEPGAGSDLAGIRTS
TH_4527|M.thermoresistible__bu      NDVVAPYFNNLCTEEQKERWMPGIASGETIIAIAMTEPGAGSDLAGIRTS
MAV_1883|M.avium_104                NDVVGPYFSSLSNDEQKERWLPGITTGELIVAVAMTEPGAGSDLAGIRTS
MLBr_00737|M.leprae_Br4923          NKLGTMGLILRGSEELKKQVLPSLAAEGAMASYALSEREAGSDAASMRTR
                                    *.:    :    .:* : : :* . :     : *::*  :***  .: * 

Mb2743c|M.bovis_AF2122/97           AVKHGDHYVLNGSKTFITNGINSDLVIVVAQTDPEKGAQGFSLLVVERGM
Rv2724c|M.tuberculosis_H37Rv        AVKHGDHYVLNGSKTFITNGINSDLVIVVAQTDPEKGAQGFSLLVVERGM
MMAR_1989|M.marinum_M               AVKQGDHYLLNGSKTFITNGINADLVIVVAQTDPEKGAQGFSLLVVERGM
MUL_3367|M.ulcerans_Agy99           AVKQGDHYLLNGSKTFITNGINADLVIVVAQTDPEKGAQGFSLLVVERGM
MAB_3040c|M.abscessus_ATCC_199      AVKDGDHYILNGAKTFITNGINADLVIVVAQTDPEKGALGFSLIVVERGM
Mflv_2118|M.gilvum_PYR-GCK          AVRDGDDWIINGSKTFISSGINCDLCVVVARTDPEAGHKGFSLFVVERDM
Mvan_4587|M.vanbaalenii_PYR-1       AVRDGDDWIINGSKTFISSGINCDLCVVVARTDPEAGHKGFSLFVVERGM
MSMEG_5197|M.smegmatis_MC2_155      AVRDGDDWIINGSKTFISSGINCDLCVVVARTDPEAGHKGFSLFVVERGM
TH_4527|M.thermoresistible__bu      AVRDGDDWIINGSKTFISSGINCDLVVVVCRTDPEAGHKGFTLFVVERGM
MAV_1883|M.avium_104                AVRDGDDWIINGAKTFISSGINCDLVVVVCRTDPDAGHKGFTLFVVEAGM
MLBr_00737|M.leprae_Br4923          AKADGDDWILNGFKCWITNGGKSTWYTVMAVTDPDKGANGISAFIVHKDD
                                    *  .**.:::** * :*:.* :.    *:. ***: *  *:: ::*. . 

Mb2743c|M.bovis_AF2122/97           AGFERGRQLDKIGLDAQDTAELSFTDVAVPAENLLGQEGMGFIYLMQNLP
Rv2724c|M.tuberculosis_H37Rv        AGFERGRQLDKIGLDAQDTAELSFTDVAVPAENLLGQEGMGFIYLMQNLP
MMAR_1989|M.marinum_M               EGFERGRHLDKIGLDAQDTAELSFSDVQVPVENLLGQEGMGFIYLMQNLP
MUL_3367|M.ulcerans_Agy99           EGFERGRHLDKIGLDAQDTAELSFSDVQVPVENLLGQEGMGFIYLMQNLP
MAB_3040c|M.abscessus_ATCC_199      EGFERGRKLDKVGLDAQDTAELSFTDVRVPAANLLGEEGQGFIYLMKNLP
Mflv_2118|M.gilvum_PYR-GCK          EGFTRGRKLDKMGLHSQDTSELHFENVRVPNANLLGKEGRGFYHLMTNLP
Mvan_4587|M.vanbaalenii_PYR-1       EGFTRGRKLDKMGLHSQDTSELHFENVRVPNANLLGKEGRGFYHLMTNLP
MSMEG_5197|M.smegmatis_MC2_155      EGFTRGRKLDKMGLHSQDTSELHFENVRVPHANLLGKEGRGFYHLMTNLP
TH_4527|M.thermoresistible__bu      EGFTRGRKLDKMGLHAQDTAELHFENVRVPHANLLGKEGHGFYHLMQNLP
MAV_1883|M.avium_104                DGFTRGRKLDKMGLHYQDTAELNFDNVRVPSANLLGKEGRGFYHLMHNLP
MLBr_00737|M.leprae_Br4923          EGFSIGPKEKKLGIKGSPTTELYFDKCRIPGDRIIGEPGTGFKTALATLD
                                     **  * : .*:*:. . *:** * .  :*  .::*: * **   : .* 

Mb2743c|M.bovis_AF2122/97           QERISIAIMAAAGMESVLEQTLQYAKERKAFGRSIGSFQNSRFLLAELAT
Rv2724c|M.tuberculosis_H37Rv        QERISIAIMAAAGMESVLEQTLQYAKERKAFGRSIGSFQNSRFLLAELAT
MMAR_1989|M.marinum_M               QERISIAIMAAAGMESVLDQTLQYTKERKAFGRSIGNFQNSRFVLAELAT
MUL_3367|M.ulcerans_Agy99           QERISIAIMAAAGMESVLDQTLQYTKERKAFGRSIGNFQNSRFVLAELAT
MAB_3040c|M.abscessus_ATCC_199      QERMSIAVMAAAAMESVLEETIAYTTERKAFGKPIKSFQNSRFLLAELAT
Mflv_2118|M.gilvum_PYR-GCK          SERLSIAISAIAGARAVFDETLQYSKDRKAFGQSIGSFQHNRFLLAEMET
Mvan_4587|M.vanbaalenii_PYR-1       SERLSIAISAIAGARAVFQETLQYAKDRKAFGQPIGSFQHNRFLLAEMET
MSMEG_5197|M.smegmatis_MC2_155      SERLSIAISAIAGARAVFDETLQYCKDRKAFGQPIGSFQHNRFLLAEMET
TH_4527|M.thermoresistible__bu      SERLSIAISAIAGARATWRETLQYAKDRKAFGKPIGSFQHNRFLLAEMDT
MAV_1883|M.avium_104                SERLSIAISAIAGARETWRQTLQYAKDRKAFGQPIGSFQHNRFMLAEMDT
MLBr_00737|M.leprae_Br4923          HTRPTIGAQAVGIAQGALDAAIVYTKDRKQFGESISTFQSIQFMLADMAM
                                      * :*.  * .  . .   :: * .:** **..* .**  :*:**::  

Mb2743c|M.bovis_AF2122/97           EATVVRIMVDEFIKLHLAGK-LTAEQAAMAKWYATEKQVYLNDRCLQLHG
Rv2724c|M.tuberculosis_H37Rv        EATVVRIMVDEFIKLHLAGK-LTAEQAAMAKWYATEKQVYLNDRCLQLHG
MMAR_1989|M.marinum_M               EATMVRIMVDEFIELHLDGK-LTAEQAAMAKWYSTEKQVSLNDRCLQLHG
MUL_3367|M.ulcerans_Agy99           EATMVRIMVDESIELHLDGK-LTAEQAAMAKWYSTEKQVSLNDRCLQLHG
MAB_3040c|M.abscessus_ATCC_199      DATVIRVMVDEFISLLNKEE-LSVEQAAMAKWYSTEKQVHLIDRCLQLHG
Mflv_2118|M.gilvum_PYR-GCK          ELEVTETYIDRCLQGVVDGE-LTAVEAAKAKWWATEVAKKVVDQCVQLHG
Mvan_4587|M.vanbaalenii_PYR-1       ELEVTENYIDRCLQGVVDGE-LTAVEAAKAKWWATETAKKVVDQCVQLHG
MSMEG_5197|M.smegmatis_MC2_155      ELEVTENYIDRCLQGVVDGE-LTAVEAAKAKWWATETAKKIVDNCVQLHG
TH_4527|M.thermoresistible__bu      ELEVSEQYIDRCLQAVVDGE-LTAVEAAKAKWWCTEVAKKVVDQCVQLHG
MAV_1883|M.avium_104                ELEIGEQYIDRCLQAVVDGE-LTAVEAAKAKWWCTETAKKVIDGCVQLHG
MLBr_00737|M.leprae_Br4923          KVEAARLIVYAAAARAERGEPDLGFISAASKCFASDIAMEVTTDAVQLFG
                                    .    .  :          :      :* :* :.::    :   .:**.*

Mb2743c|M.bovis_AF2122/97           GYGYMREYPVARAYLDSRVQTIYGGTTEIMKEIIGRGLGV
Rv2724c|M.tuberculosis_H37Rv        GYGYMREYPVARAYLDSRVQTIYGGTTEIMKEIIGRGLGV
MMAR_1989|M.marinum_M               GYGYMREYPVARAYLDSRVQTIYGGTTEIMKEIIGRSLGI
MUL_3367|M.ulcerans_Agy99           GYGYMREYPVARAYLDSRVQTIYGGTTEIMKEIIGRSLGI
MAB_3040c|M.abscessus_ATCC_199      GYGFMREYPVARAYMDSRIQTIYGGTTEIMKEIIGRSL--
Mflv_2118|M.gilvum_PYR-GCK          GYGYMLEYRVARAYVDGRIQTIFGGTTEIMKEIIGRELGV
Mvan_4587|M.vanbaalenii_PYR-1       GYGYMLEYRVARAYVDGRIQTIFGGTTEIMKEIIGRELGV
MSMEG_5197|M.smegmatis_MC2_155      GYGYMMEYRVARAYVDGRIQTIFGGTTEIMKEIIGRDLGV
TH_4527|M.thermoresistible__bu      GYGYMMEYRVARDFVDGRIQTIFGGTTEIMKEIIGRDLGL
MAV_1883|M.avium_104                GYGYMTEYRVARDYMDNRIMTIFGGTTEIMKDIIGRDLGL
MLBr_00737|M.leprae_Br4923          GAGYTSDFPVERFMRDAKITQIYEGTNQIQRVVMSRALLR
                                    * *:  :: * *   * ::  *: **.:* : ::.* *

species	id	gene	e-value	identity (len)	annotation
M. gilvum PYR-GCK	Mflv_2118	-	-	100% (380)	acyl-CoA dehydrogenase domain-containing protein
M. gilvum PYR-GCK	Mflv_4558	-	e-112	51.05% (380)	acyl-CoA dehydrogenase domain-containing protein
M. gilvum PYR-GCK	Mflv_2446	-	e-103	46.37% (386)	acyl-CoA dehydrogenase domain-containing protein