For questions or suggestions e-mail us at: ioerger@cs.tamu.edu
QRTIYTEDHEAFRESVKAFVQRHVDPRAETFIEQRYIDRELWEEAGKQGYLGLDVPEEFGGSSAGDYRYN AVLQEELARSSAALASSMSIHFDIVAPYLVELTTDEQKQRWLPKFCSGEMITAIGMTEPSGGSDLAALKT TAVKDGDDWVINGSKTFITNGARADLVVVAARTAPELKAKGITLFAVEEGMPGFERGRKLDKVGQPEADT AELFFTDVRVPAENVIGEVNQGFISMMQRLPQERMGCAVANIAHAVAVLEETVEYAKERKAFGQQIGSLQ YNKFLIAELVTKLEAAQVYVDQAVLAHSKGELTAIDAAKAKWWSSQVQNEVIDACVQLHGGYGYMKEYRV ARAWMDARVTKIWAGSNEIMKELIGRDLGF*
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. abscessus ATCC 19977 | MAB_0065c | - | - | 100% (381) | acyl-CoA dehydrogenase FadE |
| M. abscessus ATCC 19977 | MAB_3040c | - | e-119 | 55.29% (378) | acyl-CoA dehydrogenase |
| M. abscessus ATCC 19977 | MAB_2081 | - | 2e-96 | 47.14% (367) | acyl CoA dehydrogenase |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb2743c | fadE20 | 1e-119 | 54.35% (379) | acyl-CoA dehydrogenase FADE20 |
| M. gilvum PYR-GCK | Mflv_2118 | - | 1e-123 | 53.68% (380) | acyl-CoA dehydrogenase domain-containing protein |
| M. tuberculosis H37Rv | Rv2724c | fadE20 | 1e-120 | 54.88% (379) | acyl-CoA dehydrogenase FADE20 |
| M. leprae Br4923 | MLBr_00737 | fadE25 | 6e-53 | 31.82% (374) | putative acyl-CoA dehydrogenase |
| M. marinum M | MMAR_1989 | fadE20 | 1e-119 | 53.83% (379) | acyl-CoA dehydrogenase FadE20 |
| M. avium 104 | MAV_3616 | - | 1e-123 | 56.46% (379) | long-chain specific acyl-CoA dehydrogenase |
| M. smegmatis MC2 155 | MSMEG_5197 | - | 1e-123 | 53.68% (380) | long-chain specific acyl-CoA dehydrogenase |
| M. thermoresistible (build 8) | TH_3604 | - | 1e-131 | 59.10% (379) | PUTATIVE putative acyl-CoA dehydrogenase domain protein |
| M. ulcerans Agy99 | MUL_3367 | fadE20 | 1e-116 | 53.03% (379) | acyl-CoA dehydrogenase FadE20 |
| M. vanbaalenii PYR-1 | Mvan_4587 | - | 1e-124 | 54.21% (380) | acyl-CoA dehydrogenase domain-containing protein |
CLUSTAL 2.0.9 multiple sequence alignment
MAB_0065c|M.abscessus_ATCC_199 ---------MQRTIYTEDHEAFRESVKAFVQRHVDPRAETFIEQRYIDRE
TH_3604|M.thermoresistible__bu --------VMQRTLYDSDHEDFRAVVRNFVQTHIEPNDEKFAAEGRLSRE
MMAR_1989|M.marinum_M ---MGSAIKYQRTLFEPEHDLFRESYRGFLERHVAPYHDEWEKAKIVDRG
MUL_3367|M.ulcerans_Agy99 ---MGSAIKYQRTLFEPEHDLFRESYRGFLERHVALYHDEWEKAKIVDRG
MAV_3616|M.avium_104 ---MSSAIKYQRTLFESEHELFRESYRAFLDRHVAPYHDEWEKAKIVDRG
Mb2743c|M.bovis_AF2122/97 ---MGSATKYQRTLFEPEHELFRESYRAFLDRHVAAYHDEWEKTKIVDRG
Rv2724c|M.tuberculosis_H37Rv ---MGSATKYQRTLFEPEHELFRESYRAFLDRHVAPYHDEWEKTKIVDRG
Mflv_2118|M.gilvum_PYR-GCK ---------MKRTIYDAEHEAFRDTVKEYIERELVPNSEKWETERIVDRS
Mvan_4587|M.vanbaalenii_PYR-1 ---------MKRTIYDAEHEAFRETVKEYIERELVPNSEKWETERIVDRS
MSMEG_5197|M.smegmatis_MC2_155 ---------MKRLIYNEEHEAFRQTVKEYIERELVPHSEKWEAERIVDRS
MLBr_00737|M.leprae_Br4923 MVGWSGNPLFDLFKLPEEHNELRATIRALAEKEIAPHAADVDQRARFPEE
. :*: :* : : .: . .
MAB_0065c|M.abscessus_ATCC_199 LWEEAGKQGYLGLDVPEEFGGSSAGDYRYNAVLQEELARSSAALASSMSI
TH_3604|M.thermoresistible__bu LWRAAGDTGMLGLCVPEQYGGAGVNDYRFNAVMDEELTRAGMAYACGLGV
MMAR_1989|M.marinum_M VWLEAGKQGFLGMAVPEEYGGGGNPDFRYNTIITEETSAG-RYSGIGFGL
MUL_3367|M.ulcerans_Agy99 VWLEAGKQGFLGMAVPEEYGGGGNPDFRYNTIITEETSAG-RYSGIGFGL
MAV_3616|M.avium_104 VWLEAGKQGFLGMAVPEEYGGGGNPDFRYNTIITEETTRG-RYSGIGFGL
Mb2743c|M.bovis_AF2122/97 VWLEAGKQGFLGMAVPEEYGGGGNADFRYNTVITEETCAG-RYSGIGFGL
Rv2724c|M.tuberculosis_H37Rv VWLEAGKQGFLGMAVPEEYGGGGNADFRYNTVITEETCAG-RYSGIGFGL
Mflv_2118|M.gilvum_PYR-GCK AYTAAGKYGLIGFNMPEEFGGGGTDDFRFNAIIDEEIAKA-GVHGPALSL
Mvan_4587|M.vanbaalenii_PYR-1 AYTAAGKYGLIGFNMPEEYGGGGSEDFRFNAIIDEEMAKS-GVHGPALSL
MSMEG_5197|M.smegmatis_MC2_155 AYTAAGKYGLIGFNMPEEFGGGGSDDFRFNAIIDEEIAKS-GVHGPALSL
MLBr_00737|M.leprae_Br4923 ALAALNASGFNAIHVPEEYGGQGADSVAACIVIEEVARVD--ASASLIPA
. * .: :**::** . . :: * . :
MAB_0065c|M.abscessus_ATCC_199 HFDIVAPYLVELTTDEQKQRWLPKFCSGEMITAIGMTEPSGGSDLAALKT
TH_3604|M.thermoresistible__bu HTHVVSQYLVHMTTEEQRARWLPDFVSGELITAVAMSEPSGGSDLAALRT
MMAR_1989|M.marinum_M HNDIVAPYLLALATEEQKQRWLPKFCTGEFITAIAMTEPGTGSDLQGIKT
MUL_3367|M.ulcerans_Agy99 HNEIVAPYLLALATEEQKQRRLPKFCTGEFITAIAMTEPGTGSDLQGIKT
MAV_3616|M.avium_104 HNDIVAPYLLALATEEQKQRWLPKFCTGELITAIAMTEPGTGSDLQGIKT
Mb2743c|M.bovis_AF2122/97 HNDIVAPYLLALATEEQKRRWFPNFCTGELTTAIAMTEPGTGSDLQGITT
Rv2724c|M.tuberculosis_H37Rv HNDIVAPYLLALATEEQKRRWFPNFCTGELITAIAMTEPGTGSDLQGITT
Mflv_2118|M.gilvum_PYR-GCK HNDVVGPYFKDLTNDEQKKRWLPGVTSGETIIAVAMTEPGAGSDLAGIRT
Mvan_4587|M.vanbaalenii_PYR-1 HNDVVGPYFKDLTNDEQKKRWLPGIASGETIIAVAMTEPGAGSDLAGIRT
MSMEG_5197|M.smegmatis_MC2_155 HNDVVGPYFKELANDEQRRRWLPGITSGELIIAIAMTEPGAGSDLAGIRT
MLBr_00737|M.leprae_Br4923 VNKLGTMGLILRGSEELKKQVLPSLAAEGAMASYALSEREAGSDAASMRT
.: : .:* : : :* . : : .::* *** .: *
MAB_0065c|M.abscessus_ATCC_199 TAVKDGDDWVINGSKTFITNGARADLVVVAARTAPELKAKGITLFAVEEG
TH_3604|M.thermoresistible__bu RARRDGDQWVINGSKIFITNGATADLIVVAVRTGEETGSRGISLIAVEGD
MMAR_1989|M.marinum_M RAVKQGDHYLLNGSKTFITNGINADLVIVVAQTDPEKGAQGFSLLVVERG
MUL_3367|M.ulcerans_Agy99 RAVKQGDHYLLNGSKTFITNGINADLVIVVAQTDPEKGAQGFSLLVVERG
MAV_3616|M.avium_104 RAVKQGDHYVLNGSKTFITNGINSDLVIVVAQTDPDKGAQGFSLLVVERG
Mb2743c|M.bovis_AF2122/97 RAVKHGDHYVLNGSKTFITNGINSDLVIVVAQTDPEKGAQGFSLLVVERG
Rv2724c|M.tuberculosis_H37Rv RAVKHGDHYVLNGSKTFITNGINSDLVIVVAQTDPEKGAQGFSLLVVERG
Mflv_2118|M.gilvum_PYR-GCK SAVRDGDDWIINGSKTFISSGINCDLCVVVARTDPEAGHKGFSLFVVERD
Mvan_4587|M.vanbaalenii_PYR-1 SAVRDGDDWIINGSKTFISSGINCDLCVVVARTDPEAGHKGFSLFVVERG
MSMEG_5197|M.smegmatis_MC2_155 SAVRDGDDWIINGSKTFISSGINCDLCVVVARTDPEAGHKGFSLFVVERG
MLBr_00737|M.leprae_Br4923 RAKADGDDWILNGFKCWITNGGKSTWYTVMAVTDPDKGANGISAFIVHKD
* .**.:::** * :*:.* . * . * : .*:: : *. .
MAB_0065c|M.abscessus_ATCC_199 MPGFERGRKLDKVGQPEADTAELFFTDVRVPAENVIGEVNQGFISMMQRL
TH_3604|M.thermoresistible__bu APGLDRGRTLRKIGQHQGDTAELFFDDCRVPVANLIGEEGAGFRAMMEHL
MMAR_1989|M.marinum_M MEGFERGRHLDKIGLDAQDTAELSFSDVQVPVENLLGQEGMGFIYLMQNL
MUL_3367|M.ulcerans_Agy99 MEGFERGRHLDKIGLDAQDTAELSFSDVQVPVENLLGQEGMGFIYLMQNL
MAV_3616|M.avium_104 MEGFERGRHLDKIGLDAQDTAELSFTDVHVPAENLLGQEGMGFIYLMQNL
Mb2743c|M.bovis_AF2122/97 MAGFERGRQLDKIGLDAQDTAELSFTDVAVPAENLLGQEGMGFIYLMQNL
Rv2724c|M.tuberculosis_H37Rv MAGFERGRQLDKIGLDAQDTAELSFTDVAVPAENLLGQEGMGFIYLMQNL
Mflv_2118|M.gilvum_PYR-GCK MEGFTRGRKLDKMGLHSQDTSELHFENVRVPNANLLGKEGRGFYHLMTNL
Mvan_4587|M.vanbaalenii_PYR-1 MEGFTRGRKLDKMGLHSQDTSELHFENVRVPNANLLGKEGRGFYHLMTNL
MSMEG_5197|M.smegmatis_MC2_155 MEGFTRGRKLDKMGLHSQDTSELHFENVRVPHANLLGKEGRGFYHLMTNL
MLBr_00737|M.leprae_Br4923 DEGFSIGPKEKKLGIKGSPTTELYFDKCRIPGDRIIGEPGTGFKTALATL
*: * *:* *:** * . :* .::*: . ** : *
MAB_0065c|M.abscessus_ATCC_199 PQERMGCAVANIAHAVAVLEETVEYAKERKAFGQQIGSLQYNKFLIAELV
TH_3604|M.thermoresistible__bu AQERLASAVCNVAHARHVLELTCRYVTERYAFGASLGALQHIRFQMADMV
MMAR_1989|M.marinum_M PQERISIAIMAAAGMESVLDQTLQYTKERKAFGRSIGNFQNSRFVLAELA
MUL_3367|M.ulcerans_Agy99 PQERISIAIMAAAGMESVLDQTLQYTKERKAFGRSIGNFQNSRFVLAELA
MAV_3616|M.avium_104 PQERISIAVMAAAAMEQVLEQTLEYTKERKAFGKSIGSFQNSRFVLAELA
Mb2743c|M.bovis_AF2122/97 PQERISIAIMAAAGMESVLEQTLQYAKERKAFGRSIGSFQNSRFLLAELA
Rv2724c|M.tuberculosis_H37Rv PQERISIAIMAAAGMESVLEQTLQYAKERKAFGRSIGSFQNSRFLLAELA
Mflv_2118|M.gilvum_PYR-GCK PSERLSIAISAIAGARAVFDETLQYSKDRKAFGQSIGSFQHNRFLLAEME
Mvan_4587|M.vanbaalenii_PYR-1 PSERLSIAISAIAGARAVFQETLQYAKDRKAFGQPIGSFQHNRFLLAEME
MSMEG_5197|M.smegmatis_MC2_155 PSERLSIAISAIAGARAVFDETLQYCKDRKAFGQPIGSFQHNRFLLAEME
MLBr_00737|M.leprae_Br4923 DHTRPTIGAQAVGIAQGALDAAIVYTKDRKQFGESISTFQSIQFMLADMA
* . . .:: : * .:* ** :. :* :* :*::
MAB_0065c|M.abscessus_ATCC_199 TKLEAAQVYVDQAVLAHSKGE-LTAIDAAKAKWWSSQVQNEVIDACVQLH
TH_3604|M.thermoresistible__bu TELDIIQTYVDACVAAHVRGD-LTAIDAAKAKLKSSDIQSQIVDTCVQLH
MMAR_1989|M.marinum_M TEATMVRIMVDEFIELHLDGK-LTAEQAAMAKWYSTEKQVSLNDRCLQLH
MUL_3367|M.ulcerans_Agy99 TEATMVRIMVDESIELHLDGK-LTAEQAAMAKWYSTEKQVSLNDRCLQLH
MAV_3616|M.avium_104 TEATVVRMMVDEFVRLHLDHK-LTAEQAAMAKWYSTEKQVHLIDRCLQLH
Mb2743c|M.bovis_AF2122/97 TEATVVRIMVDEFIKLHLAGK-LTAEQAAMAKWYATEKQVYLNDRCLQLH
Rv2724c|M.tuberculosis_H37Rv TEATVVRIMVDEFIKLHLAGK-LTAEQAAMAKWYATEKQVYLNDRCLQLH
Mflv_2118|M.gilvum_PYR-GCK TELEVTETYIDRCLQGVVDGE-LTAVEAAKAKWWATEVAKKVVDQCVQLH
Mvan_4587|M.vanbaalenii_PYR-1 TELEVTENYIDRCLQGVVDGE-LTAVEAAKAKWWATETAKKVVDQCVQLH
MSMEG_5197|M.smegmatis_MC2_155 TELEVTENYIDRCLQGVVDGE-LTAVEAAKAKWWATETAKKIVDNCVQLH
MLBr_00737|M.leprae_Br4923 MKVEAARLIVYAAAARAERGEPDLGFISAASKCFASDIAMEVTTDAVQLF
: . : . . :* :* ::: : .:**.
MAB_0065c|M.abscessus_ATCC_199 GGYGYMKEYRVARAWMDARVTKIWAGSNEIMKELIGRDLGF------
TH_3604|M.thermoresistible__bu GGYGYMEEYEVARAWRDARVTRIWAGTNEIMREVIGRSLNLREPSKH
MMAR_1989|M.marinum_M GGYGYMREYPVARAYLDSRVQTIYGGTTEIMKEIIGRSLGI------
MUL_3367|M.ulcerans_Agy99 GGYGYMREYPVARAYLDSRVQTIYGGTTEIMKEIIGRSLGI------
MAV_3616|M.avium_104 GGYGYMREYPVARAYLDARVQTIYGGTTEIMKEIIGRSLGV------
Mb2743c|M.bovis_AF2122/97 GGYGYMREYPVARAYLDSRVQTIYGGTTEIMKEIIGRGLGV------
Rv2724c|M.tuberculosis_H37Rv GGYGYMREYPVARAYLDSRVQTIYGGTTEIMKEIIGRGLGV------
Mflv_2118|M.gilvum_PYR-GCK GGYGYMLEYRVARAYVDGRIQTIFGGTTEIMKEIIGRELGV------
Mvan_4587|M.vanbaalenii_PYR-1 GGYGYMLEYRVARAYVDGRIQTIFGGTTEIMKEIIGRELGV------
MSMEG_5197|M.smegmatis_MC2_155 GGYGYMMEYRVARAYVDGRIQTIFGGTTEIMKEIIGRDLGV------
MLBr_00737|M.leprae_Br4923 GGAGYTSDFPVERFMRDAKITQIYEGTNQIQRVVMSRALLR------
** ** :: * * *.:: *: *:.:* : ::.* *