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M. thermoresistible (build 8) TH_2818 (hypB)

annotation: nickel cation-binding GTPase, HypB
coordinates: 2036309 - 2037082
length: 258

aa seq not available

Operon Prediction Model: Genebank

Paralogs
speciesidgenee-valueidentity (len)annotation
M. thermoresistible (build 8)TH_2818hypB-100% (258)nickel cation-binding GTPase, HypB
M. thermoresistible (build 8)TH_1171ureG1e-0729.34% (167) Urease accessory protein ureG

Closest Orthologs (e-value cutoff: 1e-4)
speciesidgenee-valueidentity (len)annotation
M. bovis AF2122 / 97-----
M. gilvum PYR-GCKMflv_3978-3e-5845.85% (253) hydrogenase accessory protein HypB
M. tuberculosis H37Rv-----
M. leprae Br4923-----
M. abscessus ATCC 19977MAB_2427-2e-0729.28% (181) urease accessory protein (UreG)
M. marinum MMMAR_1871hypB1e-12081.32% (257) nickel cation-binding GTPase, HypB
M. avium 104MAV_2680hypB1e-5382.35% (119) hydrogenase accessory protein HypB
M. smegmatis MC2 155MSMEG_2271hypB1e-12080.00% (255) hydrogenase accessory protein HypB
M. ulcerans Agy99MUL_3027ureG6e-0723.98% (221) urease accessory protein UreG
M. vanbaalenii PYR-1Mvan_2357-1e-11276.17% (256) hydrogenase accessory protein HypB

CLUSTAL 2.0.9 multiple sequence alignment


TH_2818|M.thermoresistible__bu      -VGRFHRHDDGTVHSHEHGDHAHEHPHDHG---DHSGYQT--GGQRIEVL
MMAR_1871|M.marinum_M               -MGRFHRHDDGTVHTHEH-----EH-HQHG---DHTGYQT--GPARIEVL
MAV_2680|M.avium_104                --------------------------------------------------
MSMEG_2271|M.smegmatis_MC2_155      -MGRFHRHDDGTVHTHDHDHDGHVHDHAHG---DHSGYQT--GTERIEVL
Mvan_2357|M.vanbaalenii_PYR-1       -MGRFHRHDDGTAHTHDHDG---SPSHDHG---DHSGYHT--AAERVDVL
Mflv_3978|M.gilvum_PYR-GCK          MCATCGCGEDGTTITVPVQGHDHHHNHPHDQPDDHHQHHHPHPTETVTLE
MAB_2427|M.abscessus_ATCC_1997      -----------------------------------------------MPP
MUL_3027|M.ulcerans_Agy99           -----------------------------------------------MAK
                                                                                      

TH_2818|M.thermoresistible__bu      ESIFAENDSRAAINRKIFEENGIRALNLMSSPGSGKTTVLAATLDELANQ
MMAR_1871|M.marinum_M               EEIFAENDVRADLNRRAFETNGIRALNLMSSPGSGKTTVLQATLDQLASE
MAV_2680|M.avium_104                --------------------------------------------------
MSMEG_2271|M.smegmatis_MC2_155      ESIFAENDIRADINRGLFAEHGVRALNLMSSPGSGKTTLLARTLDDLGAD
Mvan_2357|M.vanbaalenii_PYR-1       EAIFSENDLRAAANRNAFEENGIRALNLMSSPGSGKTSLLAVTLDELVGE
Mflv_3978|M.gilvum_PYR-GCK          QKVLAKNDGIAARNRRWLTERDIVAFNMTSSPGSGKTTLLERTIRDLHPT
MAB_2427|M.abscessus_ATCC_1997      HLIDGQPHQHIDRPRRVRQPGEPLRIGIGGPVGSGKTALVAALCRTLRDE
MUL_3027|M.ulcerans_Agy99           HSHD-HTHDHHDRPRRVRKPGEPLRIGVGGPVGSGKTALVAAICRQLRDE
                                                                                      

TH_2818|M.thermoresistible__bu      IAIGIIEGDIATDLDAAKLGG----RGAQISLLNTNNGFGGECHLDAPMV
MMAR_1871|M.marinum_M               FAIGVIEGDIATDLDAAKLSG----RGAQVSLLNTSNGFGGECHLDAPMV
MAV_2680|M.avium_104                ------------------------------------------------MV
MSMEG_2271|M.smegmatis_MC2_155      VSVGIVEGDIETDLDAAKLGG----RGAQISLLNTANGFGGECHLDAPMV
Mvan_2357|M.vanbaalenii_PYR-1       IAIGVIEGDIATDLDAARLEG----RGAQISLLNTDNGFGGECHLDAPMV
Mflv_3978|M.gilvum_PYR-GCK          RSVAVIEGDQETLLDAERIQA----TGARVVQVNTGAG----CHLDAEMI
MAB_2427|M.abscessus_ATCC_1997      ISVAVLTNDIYTTEDADFLRRHAVLPDERITAVQTGGCPHTAIRDDITAN
MUL_3027|M.ulcerans_Agy99           LSLAVLTNDIYTTEDADFLRKHAVLPDSRIIAVQTGGCPHTAIRDDITAN
                                                                                      

TH_2818|M.thermoresistible__bu      NRALQDLDLD--HLELVVIENVGNLVCPAEFDVGEHAKAMVYSVAEGEDK
MMAR_1871|M.marinum_M               NRALPGLDLP--NLDLVIVENVGNLVCPAEFDVGEHAKAMVYSVTEGEDK
MAV_2680|M.avium_104                NRALQGLDLT--TLDLVIIENVGNLVCPAEFDVGEHAKAMVYSVTKGDDK
MSMEG_2271|M.smegmatis_MC2_155      NRALQGLDLT--RLDLVIIENVGNLVCPAEFDVGEHAKVMVYSVTEGEDK
Mvan_2357|M.vanbaalenii_PYR-1       HRALAGLNLA--GLDLVVIENVGNLVCPAEFDVGEHAKVMVYSLTEGEDK
Mflv_3978|M.gilvum_PYR-GCK          RRALDTLAPR--RARVLFIENVGNLVCPALFDLGETSKVVVISVTEGADK
MAB_2427|M.abscessus_ATCC_1997      LDAIEDLIATNEPLDLILVESGGDNLTATFSSGLIDVQIFVIDVAGGDKV
MUL_3027|M.ulcerans_Agy99           LDAIDDLIAAHDALDLILVESGGDNLTATFSSGLVDVQIFVIDVAGGDKV
                                      *:  *        ::.:*. *: : .:  .     : .* .:: * . 

TH_2818|M.thermoresistible__bu      PLKYPVMFRAVDVVLLNKIDLVPYLDVDVDRYIAHIREVNPTARILPVSA
MMAR_1871|M.marinum_M               PLKYPVMFRCVDVVLLNKIDLVPYLDADVDTYVAHIREVNAHATILPVSA
MAV_2680|M.avium_104                PMKYPVMFRAVDVVLLNKIDLVPYLDVDVDSYIGHVREVNPTATILPVSA
MSMEG_2271|M.smegmatis_MC2_155      PLKYPVMFRAVDVVLLNKIDLVAHLDADVRTYTSRVREVNPTTEILPVSA
Mvan_2357|M.vanbaalenii_PYR-1       PLKYPVMFRAVDVVLLNKIDLAPYLDADVATYTERIRQVNPTATVLPVSA
Mflv_3978|M.gilvum_PYR-GCK          PLKYPHMFAAADLVLINKSDLLPYVDFDIDACASAARSVNPGVGILTLSA
MAB_2427|M.abscessus_ATCC_1997      PRKGGPGVTFSDLLVINKTDLAPMVGADLTVMARDAAAVREGRPTAMISL
MUL_3027|M.ulcerans_Agy99           PRKGGPGVTFSDLLVVNKTDLAPLVGADLKVMARDAEAVRDGRPTVLQSL
                                    * *    .   *::::** ** . :. *:         *.        * 

TH_2818|M.thermoresistible__bu      RTGEGMDAWFDWLRQ---------FLRG---------------
MMAR_1871|M.marinum_M               RTGAGMTAWFDWLRR---------FAQGLPPE-----------
MAV_2680|M.avium_104                RTGVGMPDWLAWLRR---------FMEGTPTA-----------
MSMEG_2271|M.smegmatis_MC2_155      RTGEGMEAWYDWLRR---------FLTAGR-------------
Mvan_2357|M.vanbaalenii_PYR-1       KTGEGMSEWYRWLRA---------FAKD---------------
Mflv_3978|M.gilvum_PYR-GCK          KTGDGVEEWYDWISQRSIYDARVPIAGGRPAPEVRPHQEIRRR
MAB_2427|M.abscessus_ATCC_1997      TEDPAASEVLAWVRA--------HLTEAHQTDHAH--------
MUL_3027|M.ulcerans_Agy99           TEDPAATKVLDWVRS--------QLAAAG--------------
                                      . .      *:           :