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GRFHRHDDGTAHTHDHDGSPSHDHGDHSGYHTAAERVDVLEAIFSENDLRAAANRNAFEENGIRALNLMS SPGSGKTSLLAVTLDELVGEIAIGVIEGDIATDLDAARLEGRGAQISLLNTDNGFGGECHLDAPMVHRAL AGLNLAGLDLVVIENVGNLVCPAEFDVGEHAKVMVYSLTEGEDKPLKYPVMFRAVDVVLLNKIDLAPYLD ADVATYTERIRQVNPTATVLPVSAKTGEGMSEWYRWLRAFAKD*
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. vanbaalenii PYR-1 | Mvan_2357 | - | - | 100% (254) | hydrogenase accessory protein HypB |
| M. vanbaalenii PYR-1 | Mvan_2417 | - | 2e-53 | 48.92% (231) | hydrogenase accessory protein HypB |
| M. vanbaalenii PYR-1 | Mvan_3080 | - | 9e-06 | 30.13% (156) | urease accessory protein UreG |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb1883 | ureG | 4e-07 | 27.17% (184) | urease accessory protein ureG |
| M. gilvum PYR-GCK | Mflv_3978 | - | 8e-56 | 47.79% (249) | hydrogenase accessory protein HypB |
| M. tuberculosis H37Rv | Rv1852 | ureG | 4e-07 | 27.17% (184) | urease accessory protein ureG |
| M. leprae Br4923 | - | - | - | - | - |
| M. abscessus ATCC 19977 | MAB_2427 | - | 1e-07 | 29.95% (187) | urease accessory protein (UreG) |
| M. marinum M | MMAR_1871 | hypB | 1e-112 | 75.89% (253) | nickel cation-binding GTPase, HypB |
| M. avium 104 | MAV_2680 | hypB | 9e-49 | 75.86% (116) | hydrogenase accessory protein HypB |
| M. smegmatis MC2 155 | MSMEG_2271 | hypB | 1e-113 | 75.59% (254) | hydrogenase accessory protein HypB |
| M. thermoresistible (build 8) | TH_2818 | - | 1e-113 | 76.17% (256) | PUTATIVE nickel cation-binding GTPase, HypB |
| M. ulcerans Agy99 | MUL_3027 | ureG | 2e-06 | 27.32% (183) | urease accessory protein UreG |
CLUSTAL 2.0.9 multiple sequence alignment
MMAR_1871|M.marinum_M -MGRFHRHDDGTVHTHEH-----EH-HQHG---DHTGYQT--GPARIEVL
TH_2818|M.thermoresistible__bu -VGRFHRHDDGTVHSHEHGDHAHEHPHDHG---DHSGYQT--GGQRIEVL
MAV_2680|M.avium_104 --------------------------------------------------
MSMEG_2271|M.smegmatis_MC2_155 -MGRFHRHDDGTVHTHDHDHDGHVHDHAHG---DHSGYQT--GTERIEVL
Mvan_2357|M.vanbaalenii_PYR-1 -MGRFHRHDDGTAHTHDHDG---SPSHDHG---DHSGYHT--AAERVDVL
Mflv_3978|M.gilvum_PYR-GCK MCATCGCGEDGTTITVPVQGHDHHHNHPHDQPDDHHQHHHPHPTETVTLE
Mb1883|M.bovis_AF2122/97 --MATHSHP-----------------------------------------
Rv1852|M.tuberculosis_H37Rv --MATHSHP-----------------------------------------
MUL_3027|M.ulcerans_Agy99 --MAKHSHD-----------------------------------------
MAB_2427|M.abscessus_ATCC_1997 --MPPHLIDG----------------------------------------
MMAR_1871|M.marinum_M EEIFAENDVRADLNRRAFETNGIRALNLMSSPGSGKTTVLQATLDQLASE
TH_2818|M.thermoresistible__bu ESIFAENDSRAAINRKIFEENGIRALNLMSSPGSGKTTVLAATLDELANQ
MAV_2680|M.avium_104 --------------------------------------------------
MSMEG_2271|M.smegmatis_MC2_155 ESIFAENDIRADINRGLFAEHGVRALNLMSSPGSGKTTLLARTLDDLGAD
Mvan_2357|M.vanbaalenii_PYR-1 EAIFSENDLRAAANRNAFEENGIRALNLMSSPGSGKTSLLAVTLDELVGE
Mflv_3978|M.gilvum_PYR-GCK QKVLAKNDGIAARNRRWLTERDIVAFNMTSSPGSGKTTLLERTIRDLHPT
Mb1883|M.bovis_AF2122/97 -----HSHTVPARPRRVRKPGEPLRIGVGGPVGSGKTALVAALCRQLRGE
Rv1852|M.tuberculosis_H37Rv -----HSHTVPARPRRVRKPGEPLRIGVGGPVGSGKTALVAALCRQLRGE
MUL_3027|M.ulcerans_Agy99 -----HTHDHHDRPRRVRKPGEPLRIGVGGPVGSGKTALVAAICRQLRDE
MAB_2427|M.abscessus_ATCC_1997 -----QPHQHIDRPRRVRQPGEPLRIGIGGPVGSGKTALVAALCRTLRDE
MMAR_1871|M.marinum_M FAIGVIEGDIATDLDAAKLSG----RGAQVSLLNTSNGFGGECHLDAPMV
TH_2818|M.thermoresistible__bu IAIGIIEGDIATDLDAAKLGG----RGAQISLLNTNNGFGGECHLDAPMV
MAV_2680|M.avium_104 ------------------------------------------------MV
MSMEG_2271|M.smegmatis_MC2_155 VSVGIVEGDIETDLDAAKLGG----RGAQISLLNTANGFGGECHLDAPMV
Mvan_2357|M.vanbaalenii_PYR-1 IAIGVIEGDIATDLDAARLEG----RGAQISLLNTDNGFGGECHLDAPMV
Mflv_3978|M.gilvum_PYR-GCK RSVAVIEGDQETLLDAERIQA----TGARVVQVNTGAG----CHLDAEMI
Mb1883|M.bovis_AF2122/97 LSLAVLTNDIYTTEDADFLRTHAVLPDDRIAAVQTGGCPHTAIRDDITAN
Rv1852|M.tuberculosis_H37Rv LSLAVLTNDIYTTEDADFLRTHAVLPDDRIAAVQTGGCPHTAIRDDITAN
MUL_3027|M.ulcerans_Agy99 LSLAVLTNDIYTTEDADFLRKHAVLPDSRIIAVQTGGCPHTAIRDDITAN
MAB_2427|M.abscessus_ATCC_1997 ISVAVLTNDIYTTEDADFLRRHAVLPDERITAVQTGGCPHTAIRDDITAN
MMAR_1871|M.marinum_M NRALPGLDLPN--LDLVIVENVGNLVCPAEFDVGEHAKAMVYSVTEGEDK
TH_2818|M.thermoresistible__bu NRALQDLDLDH--LELVVIENVGNLVCPAEFDVGEHAKAMVYSVAEGEDK
MAV_2680|M.avium_104 NRALQGLDLTT--LDLVIIENVGNLVCPAEFDVGEHAKAMVYSVTKGDDK
MSMEG_2271|M.smegmatis_MC2_155 NRALQGLDLTR--LDLVIIENVGNLVCPAEFDVGEHAKVMVYSVTEGEDK
Mvan_2357|M.vanbaalenii_PYR-1 HRALAGLNLAG--LDLVVIENVGNLVCPAEFDVGEHAKVMVYSLTEGEDK
Mflv_3978|M.gilvum_PYR-GCK RRALDTLAPRR--ARVLFIENVGNLVCPALFDLGETSKVVVISVTEGADK
Mb1883|M.bovis_AF2122/97 LDAIDELMAAHDALDLILVESGGDNLTATFSSGLVDAQIFVIDVAGGDKV
Rv1852|M.tuberculosis_H37Rv LDAIDELMAAHDALDLILVESGGDNLTATFSSGLVDAQIFVIDVAGGDKV
MUL_3027|M.ulcerans_Agy99 LDAIDDLIAAHDALDLILVESGGDNLTATFSSGLVDVQIFVIDVAGGDKV
MAB_2427|M.abscessus_ATCC_1997 LDAIEDLIATNEPLDLILVESGGDNLTATFSSGLIDVQIFVIDVAGGDKV
*: * ::.:*. *: : .: . : .* .:: * .
MMAR_1871|M.marinum_M PLKYPVMFRCVDVVLLNKIDLVPYLDADVDTYVAHIREVNAHATILPVSA
TH_2818|M.thermoresistible__bu PLKYPVMFRAVDVVLLNKIDLVPYLDVDVDRYIAHIREVNPTARILPVSA
MAV_2680|M.avium_104 PMKYPVMFRAVDVVLLNKIDLVPYLDVDVDSYIGHVREVNPTATILPVSA
MSMEG_2271|M.smegmatis_MC2_155 PLKYPVMFRAVDVVLLNKIDLVAHLDADVRTYTSRVREVNPTTEILPVSA
Mvan_2357|M.vanbaalenii_PYR-1 PLKYPVMFRAVDVVLLNKIDLAPYLDADVATYTERIRQVNPTATVLPVSA
Mflv_3978|M.gilvum_PYR-GCK PLKYPHMFAAADLVLINKSDLLPYVDFDIDACASAARSVNPGVGILTLSA
Mb1883|M.bovis_AF2122/97 PRKGGPGVTYSDLLVVNKTDLAALVGADLAVMARDADAVRDGRPTVLQSL
Rv1852|M.tuberculosis_H37Rv PRKGGPGVTYSDLLVVNKTDLAALVGADLAVMARDADAVRDGRPTVLQSL
MUL_3027|M.ulcerans_Agy99 PRKGGPGVTFSDLLVVNKTDLAPLVGADLKVMARDAEAVRDGRPTVLQSL
MAB_2427|M.abscessus_ATCC_1997 PRKGGPGVTFSDLLVINKTDLAPMVGADLTVMARDAAAVREGRPTAMISL
* * . *::::** ** . :. *: *. *
MMAR_1871|M.marinum_M RTGAGMTAWFDWLRR---------FAQGLPPE-----------
TH_2818|M.thermoresistible__bu RTGEGMDAWFDWLRQ---------FLRG---------------
MAV_2680|M.avium_104 RTGVGMPDWLAWLRR---------FMEGTPTA-----------
MSMEG_2271|M.smegmatis_MC2_155 RTGEGMEAWYDWLRR---------FLTAGR-------------
Mvan_2357|M.vanbaalenii_PYR-1 KTGEGMSEWYRWLRA---------FAKD---------------
Mflv_3978|M.gilvum_PYR-GCK KTGDGVEEWYDWISQRSIYDARVPIAGGRPAPEVRPHQEIRRR
Mb1883|M.bovis_AF2122/97 TEDPAASDVVAWVRS--------QLAADGV-------------
Rv1852|M.tuberculosis_H37Rv TEDPAASDVVAWVRS--------QLAADGV-------------
MUL_3027|M.ulcerans_Agy99 TEDPAATKVLDWVRS--------QLAAAG--------------
MAB_2427|M.abscessus_ATCC_1997 TEDPAASEVLAWVRA--------HLTEAHQTDHAH--------
. . *: :