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GRFHRHDDGTVHTHEHEHHQHGDHTGYQTGPARIEVLEEIFAENDVRADLNRRAFETNGIRALNLMSSPG SGKTTVLQATLDQLASEFAIGVIEGDIATDLDAAKLSGRGAQVSLLNTSNGFGGECHLDAPMVNRALPGL DLPNLDLVIVENVGNLVCPAEFDVGEHAKAMVYSVTEGEDKPLKYPVMFRCVDVVLLNKIDLVPYLDADV DTYVAHIREVNAHATILPVSARTGAGMTAWFDWLRRFAQGLPPE*
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. marinum M | MMAR_1871 | hypB | - | 100% (255) | nickel cation-binding GTPase, HypB |
| M. marinum M | MMAR_2726 | ureG | 1e-06 | 24.49% (245) | urease accessory protein UreG |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | - | - | - | - | - |
| M. gilvum PYR-GCK | Mflv_3978 | - | 3e-54 | 46.47% (241) | hydrogenase accessory protein HypB |
| M. tuberculosis H37Rv | - | - | - | - | - |
| M. leprae Br4923 | - | - | - | - | - |
| M. abscessus ATCC 19977 | MAB_2427 | - | 5e-06 | 28.73% (181) | urease accessory protein (UreG) |
| M. avium 104 | MAV_2680 | hypB | 2e-54 | 80.99% (121) | hydrogenase accessory protein HypB |
| M. smegmatis MC2 155 | MSMEG_2271 | hypB | 1e-115 | 77.17% (254) | hydrogenase accessory protein HypB |
| M. thermoresistible (build 8) | TH_2818 | - | 1e-120 | 81.32% (257) | PUTATIVE nickel cation-binding GTPase, HypB |
| M. ulcerans Agy99 | MUL_3027 | ureG | 4e-06 | 24.08% (245) | urease accessory protein UreG |
| M. vanbaalenii PYR-1 | Mvan_2357 | - | 1e-112 | 75.89% (253) | hydrogenase accessory protein HypB |
CLUSTAL 2.0.9 multiple sequence alignment
MMAR_1871|M.marinum_M -MGRFHRHDDGTVHTHEH-----EH-HQHG---DHTGYQT--GPARIEVL
TH_2818|M.thermoresistible__bu -VGRFHRHDDGTVHSHEHGDHAHEHPHDHG---DHSGYQT--GGQRIEVL
MAV_2680|M.avium_104 --------------------------------------------------
MSMEG_2271|M.smegmatis_MC2_155 -MGRFHRHDDGTVHTHDHDHDGHVHDHAHG---DHSGYQT--GTERIEVL
Mvan_2357|M.vanbaalenii_PYR-1 -MGRFHRHDDGTAHTHDHDG---SPSHDHG---DHSGYHT--AAERVDVL
Mflv_3978|M.gilvum_PYR-GCK MCATCGCGEDGTTITVPVQGHDHHHNHPHDQPDDHHQHHHPHPTETVTLE
MAB_2427|M.abscessus_ATCC_1997 -----------------------------------------------MPP
MUL_3027|M.ulcerans_Agy99 -----------------------------------------------MAK
MMAR_1871|M.marinum_M EEIFAENDVRADLNRRAFETNGIRALNLMSSPGSGKTTVLQATLDQLASE
TH_2818|M.thermoresistible__bu ESIFAENDSRAAINRKIFEENGIRALNLMSSPGSGKTTVLAATLDELANQ
MAV_2680|M.avium_104 --------------------------------------------------
MSMEG_2271|M.smegmatis_MC2_155 ESIFAENDIRADINRGLFAEHGVRALNLMSSPGSGKTTLLARTLDDLGAD
Mvan_2357|M.vanbaalenii_PYR-1 EAIFSENDLRAAANRNAFEENGIRALNLMSSPGSGKTSLLAVTLDELVGE
Mflv_3978|M.gilvum_PYR-GCK QKVLAKNDGIAARNRRWLTERDIVAFNMTSSPGSGKTTLLERTIRDLHPT
MAB_2427|M.abscessus_ATCC_1997 HLIDGQPHQHIDRPRRVRQPGEPLRIGIGGPVGSGKTALVAALCRTLRDE
MUL_3027|M.ulcerans_Agy99 HSHD-HTHDHHDRPRRVRKPGEPLRIGVGGPVGSGKTALVAAICRQLRDE
MMAR_1871|M.marinum_M FAIGVIEGDIATDLDAAKLSG----RGAQVSLLNTSNGFGGECHLDAPMV
TH_2818|M.thermoresistible__bu IAIGIIEGDIATDLDAAKLGG----RGAQISLLNTNNGFGGECHLDAPMV
MAV_2680|M.avium_104 ------------------------------------------------MV
MSMEG_2271|M.smegmatis_MC2_155 VSVGIVEGDIETDLDAAKLGG----RGAQISLLNTANGFGGECHLDAPMV
Mvan_2357|M.vanbaalenii_PYR-1 IAIGVIEGDIATDLDAARLEG----RGAQISLLNTDNGFGGECHLDAPMV
Mflv_3978|M.gilvum_PYR-GCK RSVAVIEGDQETLLDAERIQA----TGARVVQVNTGAG----CHLDAEMI
MAB_2427|M.abscessus_ATCC_1997 ISVAVLTNDIYTTEDADFLRRHAVLPDERITAVQTGGCPHTAIRDDITAN
MUL_3027|M.ulcerans_Agy99 LSLAVLTNDIYTTEDADFLRKHAVLPDSRIIAVQTGGCPHTAIRDDITAN
MMAR_1871|M.marinum_M NRALPGLDLP--NLDLVIVENVGNLVCPAEFDVGEHAKAMVYSVTEGEDK
TH_2818|M.thermoresistible__bu NRALQDLDLD--HLELVVIENVGNLVCPAEFDVGEHAKAMVYSVAEGEDK
MAV_2680|M.avium_104 NRALQGLDLT--TLDLVIIENVGNLVCPAEFDVGEHAKAMVYSVTKGDDK
MSMEG_2271|M.smegmatis_MC2_155 NRALQGLDLT--RLDLVIIENVGNLVCPAEFDVGEHAKVMVYSVTEGEDK
Mvan_2357|M.vanbaalenii_PYR-1 HRALAGLNLA--GLDLVVIENVGNLVCPAEFDVGEHAKVMVYSLTEGEDK
Mflv_3978|M.gilvum_PYR-GCK RRALDTLAPR--RARVLFIENVGNLVCPALFDLGETSKVVVISVTEGADK
MAB_2427|M.abscessus_ATCC_1997 LDAIEDLIATNEPLDLILVESGGDNLTATFSSGLIDVQIFVIDVAGGDKV
MUL_3027|M.ulcerans_Agy99 LDAIDDLIAAHDALDLILVESGGDNLTATFSSGLVDVQIFVIDVAGGDKV
*: * ::.:*. *: : .: . : .* .:: * .
MMAR_1871|M.marinum_M PLKYPVMFRCVDVVLLNKIDLVPYLDADVDTYVAHIREVNAHATILPVSA
TH_2818|M.thermoresistible__bu PLKYPVMFRAVDVVLLNKIDLVPYLDVDVDRYIAHIREVNPTARILPVSA
MAV_2680|M.avium_104 PMKYPVMFRAVDVVLLNKIDLVPYLDVDVDSYIGHVREVNPTATILPVSA
MSMEG_2271|M.smegmatis_MC2_155 PLKYPVMFRAVDVVLLNKIDLVAHLDADVRTYTSRVREVNPTTEILPVSA
Mvan_2357|M.vanbaalenii_PYR-1 PLKYPVMFRAVDVVLLNKIDLAPYLDADVATYTERIRQVNPTATVLPVSA
Mflv_3978|M.gilvum_PYR-GCK PLKYPHMFAAADLVLINKSDLLPYVDFDIDACASAARSVNPGVGILTLSA
MAB_2427|M.abscessus_ATCC_1997 PRKGGPGVTFSDLLVINKTDLAPMVGADLTVMARDAAAVREGRPTAMISL
MUL_3027|M.ulcerans_Agy99 PRKGGPGVTFSDLLVVNKTDLAPLVGADLKVMARDAEAVRDGRPTVLQSL
* * . *::::** ** . :. *: *. *
MMAR_1871|M.marinum_M RTGAGMTAWFDWLRR---------FAQGLPPE-----------
TH_2818|M.thermoresistible__bu RTGEGMDAWFDWLRQ---------FLRG---------------
MAV_2680|M.avium_104 RTGVGMPDWLAWLRR---------FMEGTPTA-----------
MSMEG_2271|M.smegmatis_MC2_155 RTGEGMEAWYDWLRR---------FLTAGR-------------
Mvan_2357|M.vanbaalenii_PYR-1 KTGEGMSEWYRWLRA---------FAKD---------------
Mflv_3978|M.gilvum_PYR-GCK KTGDGVEEWYDWISQRSIYDARVPIAGGRPAPEVRPHQEIRRR
MAB_2427|M.abscessus_ATCC_1997 TEDPAASEVLAWVRA--------HLTEAHQTDHAH--------
MUL_3027|M.ulcerans_Agy99 TEDPAATKVLDWVRS--------QLAAAG--------------
. . *: :