For questions or suggestions e-mail us at: ioerger@cs.tamu.edu

M. avium 104 MAV_2680 (hypB)

annotation: hydrogenase accessory protein HypB
coordinates: 2715631 - 2716002
length: 123

MVNRALQGLDLTTLDLVIIENVGNLVCPAEFDVGEHAKAMVYSVTKGDDKPMKYPVMFRAVDVVLLNKID
LVPYLDVDVDSYIGHVREVNPTATILPVSARTGVGMPDWLAWLRRFMEGTPTA
Operon Prediction Model: Genebank

Paralogs
speciesidgenee-valueidentity (len)annotation
M. avium 104MAV_2680hypB-100% (123)hydrogenase accessory protein HypB

Closest Orthologs (e-value cutoff: 1e-4)
speciesidgenee-valueidentity (len)annotation
M. bovis AF2122 / 97-----
M. gilvum PYR-GCKMflv_3978-2e-3053.10% (113) hydrogenase accessory protein HypB
M. tuberculosis H37Rv-----
M. leprae Br4923-----
M. abscessus ATCC 19977-----
M. marinum MMMAR_1871hypB7e-5580.99% (121) nickel cation-binding GTPase, HypB
M. smegmatis MC2 155MSMEG_2271hypB2e-5182.05% (117) hydrogenase accessory protein HypB
M. thermoresistible (build 8)TH_2818-3e-5482.35% (119) PUTATIVE nickel cation-binding GTPase, HypB
M. ulcerans Agy99-----
M. vanbaalenii PYR-1Mvan_2357-3e-4975.86% (116) hydrogenase accessory protein HypB

CLUSTAL 2.0.9 multiple sequence alignment


MMAR_1871|M.marinum_M               -MGRFHRHDDGTVHTHEH-----EH-HQHG---DHTGYQT--GPARIEVL
TH_2818|M.thermoresistible__bu      -VGRFHRHDDGTVHSHEHGDHAHEHPHDHG---DHSGYQT--GGQRIEVL
Mvan_2357|M.vanbaalenii_PYR-1       -MGRFHRHDDGTAHTHDHDG---SPSHDHG---DHSGYHT--AAERVDVL
MSMEG_2271|M.smegmatis_MC2_155      -MGRFHRHDDGTVHTHDHDHDGHVHDHAHG---DHSGYQT--GTERIEVL
MAV_2680|M.avium_104                --------------------------------------------------
Mflv_3978|M.gilvum_PYR-GCK          MCATCGCGEDGTTITVPVQGHDHHHNHPHDQPDDHHQHHHPHPTETVTLE
                                                                                      

MMAR_1871|M.marinum_M               EEIFAENDVRADLNRRAFETNGIRALNLMSSPGSGKTTVLQATLDQLASE
TH_2818|M.thermoresistible__bu      ESIFAENDSRAAINRKIFEENGIRALNLMSSPGSGKTTVLAATLDELANQ
Mvan_2357|M.vanbaalenii_PYR-1       EAIFSENDLRAAANRNAFEENGIRALNLMSSPGSGKTSLLAVTLDELVGE
MSMEG_2271|M.smegmatis_MC2_155      ESIFAENDIRADINRGLFAEHGVRALNLMSSPGSGKTTLLARTLDDLGAD
MAV_2680|M.avium_104                --------------------------------------------------
Mflv_3978|M.gilvum_PYR-GCK          QKVLAKNDGIAARNRRWLTERDIVAFNMTSSPGSGKTTLLERTIRDLHPT
                                                                                      

MMAR_1871|M.marinum_M               FAIGVIEGDIATDLDAAKLSGRGAQVSLLNTSNGFGGECHLDAPMVNRAL
TH_2818|M.thermoresistible__bu      IAIGIIEGDIATDLDAAKLGGRGAQISLLNTNNGFGGECHLDAPMVNRAL
Mvan_2357|M.vanbaalenii_PYR-1       IAIGVIEGDIATDLDAARLEGRGAQISLLNTDNGFGGECHLDAPMVHRAL
MSMEG_2271|M.smegmatis_MC2_155      VSVGIVEGDIETDLDAAKLGGRGAQISLLNTANGFGGECHLDAPMVNRAL
MAV_2680|M.avium_104                --------------------------------------------MVNRAL
Mflv_3978|M.gilvum_PYR-GCK          RSVAVIEGDQETLLDAERIQATGARVVQVNTGAG----CHLDAEMIRRAL
                                                                                *:.***

MMAR_1871|M.marinum_M               PGLDLPNLDLVIVENVGNLVCPAEFDVGEHAKAMVYSVTEGEDKPLKYPV
TH_2818|M.thermoresistible__bu      QDLDLDHLELVVIENVGNLVCPAEFDVGEHAKAMVYSVAEGEDKPLKYPV
Mvan_2357|M.vanbaalenii_PYR-1       AGLNLAGLDLVVIENVGNLVCPAEFDVGEHAKVMVYSLTEGEDKPLKYPV
MSMEG_2271|M.smegmatis_MC2_155      QGLDLTRLDLVIIENVGNLVCPAEFDVGEHAKVMVYSVTEGEDKPLKYPV
MAV_2680|M.avium_104                QGLDLTTLDLVIIENVGNLVCPAEFDVGEHAKAMVYSVTKGDDKPMKYPV
Mflv_3978|M.gilvum_PYR-GCK          DTLAPRRARVLFIENVGNLVCPALFDLGETSKVVVISVTEGADKPLKYPH
                                      *      ::.:********** **:** :*.:* *:::* ***:*** 

MMAR_1871|M.marinum_M               MFRCVDVVLLNKIDLVPYLDADVDTYVAHIREVNAHATILPVSARTGAGM
TH_2818|M.thermoresistible__bu      MFRAVDVVLLNKIDLVPYLDVDVDRYIAHIREVNPTARILPVSARTGEGM
Mvan_2357|M.vanbaalenii_PYR-1       MFRAVDVVLLNKIDLAPYLDADVATYTERIRQVNPTATVLPVSAKTGEGM
MSMEG_2271|M.smegmatis_MC2_155      MFRAVDVVLLNKIDLVAHLDADVRTYTSRVREVNPTTEILPVSARTGEGM
MAV_2680|M.avium_104                MFRAVDVVLLNKIDLVPYLDVDVDSYIGHVREVNPTATILPVSARTGVGM
Mflv_3978|M.gilvum_PYR-GCK          MFAAADLVLINKSDLLPYVDFDIDACASAARSVNPGVGILTLSAKTGDGV
                                    ** ..*:**:** ** .::* *:       *.**. . :*.:**:** *:

MMAR_1871|M.marinum_M               TAWFDWLRR---------FAQGLPPE-----------
TH_2818|M.thermoresistible__bu      DAWFDWLRQ---------FLRG---------------
Mvan_2357|M.vanbaalenii_PYR-1       SEWYRWLRA---------FAKD---------------
MSMEG_2271|M.smegmatis_MC2_155      EAWYDWLRR---------FLTAGR-------------
MAV_2680|M.avium_104                PDWLAWLRR---------FMEGTPTA-----------
Mflv_3978|M.gilvum_PYR-GCK          EEWYDWISQRSIYDARVPIAGGRPAPEVRPHQEIRRR
                                      *  *:           :