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M. thermoresistible (build 8) TH_2777 (-)

annotation: acyl-CoA dehydrogenase domain protein
coordinates: 1452982 - 1453995
length: 338

aa seq not available

Operon Prediction Model: Genebank

Paralogs
speciesidgenee-valueidentity (len)annotation
M. thermoresistible (build 8)TH_2777--100% (338)acyl-CoA dehydrogenase domain protein
M. thermoresistible (build 8)TH_0804-2e-4539.32% (323) acyl-CoA dehydrogenase
M. thermoresistible (build 8)TH_4038-4e-4434.69% (343) PUTATIVE putative acyl-CoA dehydrogenase domain protein

Closest Orthologs (e-value cutoff: 1e-4)
speciesidgenee-valueidentity (len)annotation
M. bovis AF2122 / 97Mb3594fadE331e-3836.48% (318) acyl-CoA dehydrogenase FADE33
M. gilvum PYR-GCKMflv_1795-1e-11263.20% (337) acyl-CoA dehydrogenase domain-containing protein
M. tuberculosis H37RvRv3564fadE331e-3836.48% (318) acyl-CoA dehydrogenase FADE33
M. leprae Br4923MLBr_00737fadE252e-1523.73% (375) putative acyl-CoA dehydrogenase
M. abscessus ATCC 19977MAB_3123-3e-4535.64% (362) putative acyl-CoA dehydrogenase
M. marinum MMMAR_2861fadE181e-4036.58% (339) acyl-CoA dehydrogenase FadE18
M. avium 104MAV_2570-2e-4135.50% (338) putative acyl-CoA dehydrogenase
M. smegmatis MC2 155MSMEG_5618-1e-10561.38% (347) acyl-CoA dehydrogenase
M. ulcerans Agy99MUL_2893fadE187e-4136.58% (339) acyl-CoA dehydrogenase FadE18
M. vanbaalenii PYR-1Mvan_4955-1e-10861.61% (336) acyl-CoA dehydrogenase domain-containing protein

CLUSTAL 2.0.9 multiple sequence alignment


Mflv_1795|M.gilvum_PYR-GCK          -----------------------------------MRAEFAEFHDELRSV
Mvan_4955|M.vanbaalenii_PYR-1       -----------------------------------MTHGFSEFHDELRSV
TH_2777|M.thermoresistible__bu      -----------------------------------MTDQFTEFHDELRAV
MSMEG_5618|M.smegmatis_MC2_155      -------------------------------MMTDFTTDFSAIHDELRSV
Mb3594|M.bovis_AF2122/97            ---------------------------------MTPPEERQMLRETVASL
Rv3564|M.tuberculosis_H37Rv         ---------------------------------MTPPEERQMLRETVASL
MMAR_2861|M.marinum_M               -------------------------------MDFRYSTEQDDFRESLRGF
MUL_2893|M.ulcerans_Agy99           -------------------------------MDFRYSTEQDDFRESLRGF
MAV_2570|M.avium_104                -------------------------------MTALSADERQELAQSVRSA
MAB_3123|M.abscessus_ATCC_1997      MSASEDHQTRMSASEDNQTRMSASEDNQAQINEFEFTEEHGDLRSLVRSW
MLBr_00737|M.leprae_Br4923          ---------------------MVGWSGNPLFDLFKLPEEHNELRATIRAL
                                                                              :   : . 

Mflv_1795|M.gilvum_PYR-GCK          ASDLLAKDG---------------------HAPEWRVLADAGWTGLEVPD
Mvan_4955|M.vanbaalenii_PYR-1       AGDLLAKD----------------------RVVDWSVLVDAGWTGLEVPD
TH_2777|M.thermoresistible__bu      AAEVLAKD----------------------RTVDWPVLADAGWVGLEVAD
MSMEG_5618|M.smegmatis_MC2_155      AADLLAKD-----------------------SVDWPLLVQAGWVGLDAPE
Mb3594|M.bovis_AF2122/97            VAKHAGPAAVRAAMASDR---------GYDESLWRLLCEQVGAAALVIPE
Rv3564|M.tuberculosis_H37Rv         VAKHAGPAAVRAAMASDR---------GYDESLWRLLCEQVGAAALVIPE
MMAR_2861|M.marinum_M               LRDQAPPARVRQVAAVG----------GHDKKLWHRLCAELELPALHAPP
MUL_2893|M.ulcerans_Agy99           LRDQAPPARVRQVAAVG----------GHDKKLWHRLCAELELPALHAPP
MAV_2570|M.avium_104                CERLASEDRVRAVAYAEGNRGGGDGHSGFDTVLWDVLCNQVGVAGIALPE
MAB_3123|M.abscessus_ATCC_1997      CERVWTPKHVRQIAEAGS----------VDLDAWRALGSELGVVGLSLPE
MLBr_00737|M.leprae_Br4923          AEKEIAPHAADVDQRAR------------FPEEALAALNASGFNAIHVPE
                                                                                .:  . 

Mflv_1795|M.gilvum_PYR-GCK          TLGGAGASFAESAVILDQIGRAAGVTGYLGGAVLATGVLNLLRPSDSRDH
Mvan_4955|M.vanbaalenii_PYR-1       GLGGSGATFVETAMILDQIGRAASANRYLGSAVLAVGVLNLLEPSEIRDE
TH_2777|M.thermoresistible__bu      EFGGAGASFGEVAVICSEMGRAATASSYLGGAVLGVGALNAVQPDAARDD
MSMEG_5618|M.smegmatis_MC2_155      SLGGAGATFAEVAVICEELGRAAATTGYLGGAVLGVGALLAVAPNTSRDN
Mb3594|M.bovis_AF2122/97            ELGGAGGELADAAIVVQELGRALVPSPLLG-TTLAELALLAAAKPDAQA-
Rv3564|M.tuberculosis_H37Rv         ELGGAGGELADAAIVVQELGRALVPSPLLG-TTLAELALLAAAKPDAQA-
MMAR_2861|M.marinum_M               EYGGAGGTLVETAIAFGELGRALTPVPFAA-TILAIEAILRMGDSEQRKG
MUL_2893|M.ulcerans_Agy99           EYGGAGGTLVETAIAFGELGRALTPVPFAA-TILAIEAILRMGDSEQRKG
MAV_2570|M.avium_104                HLGGAGYGVSALGVVAHELGRALAPVPFVGSTVLATGLLLDLTERDPDAD
MAB_3123|M.abscessus_ATCC_1997      QHGGGGLGVIELSIVAEELGRALACLPWISSAALGATALVSSGDDSALAE
MLBr_00737|M.leprae_Br4923          EYGGQGADSVAACIVIEEVARVDASASLIPAVNKLGTMGLILRGSEELKK
                                      ** *       :   ::.*.         .                  

Mflv_1795|M.gilvum_PYR-GCK          L-LAAVAGGEPRLAVVTG--------------DFSMS-AGKLTGRAEFVP
Mvan_4955|M.vanbaalenii_PYR-1       L-LTAVASGPGRLGVATD--------------GFAVN-GGRLAGRAGFVP
TH_2777|M.thermoresistible__bu      L-LTAVAAGAERTALVLG--------------PFTFT-GGRLTGRAEFVP
MSMEG_5618|M.smegmatis_MC2_155      L-LTEVVEGRTRVSLALPG----DLVPGDPRVPFTVTTDGRVHGRAAFVP
Mb3594|M.bovis_AF2122/97            --LTELAQGSAIGALVLD-----PDY----------------------VV
Rv3564|M.tuberculosis_H37Rv         --LTELAQGSAIGALVLD-----PDY----------------------VV
MMAR_2861|M.marinum_M               L-LSGLLSGDRIGALAAAG----PDLSVTSVRAGRRDGRPVLTGECAPVL
MUL_2893|M.ulcerans_Agy99           L-LSGLLSGDRIGALAAAG----PDLSVTSVRAGRRDGRPVLTGECAPVL
MAV_2570|M.avium_104                KRLTGLIEGRRTAAAALTGDGGLWRRSAVTLRAARAGDDWNIDGTVRHVL
MAB_3123|M.abscessus_ATCC_1997      W-VPALAAGEKTITLAGGR---TRLADAITVSAESDTDGWKLTGDTEHVP
MLBr_00737|M.leprae_Br4923          QVLPSLAAEGAMASYALSEREAGSDAASMRTRAKADGDDWILNGFKCWIT
                                      :. :         .                                : 

Mflv_1795|M.gilvum_PYR-GCK          DAVGADRLLVVTG-------PEVAVVETAAATVT--------AQPVVDET
Mvan_4955|M.vanbaalenii_PYR-1       DAVGADRLLVLVD-------GAVAVVDAAQMSVV--------PQPVVDET
TH_2777|M.thermoresistible__bu      DASGADRLLVLATDSD----GTPVLTATAAATVT--------AQPVLDET
MSMEG_5618|M.smegmatis_MC2_155      DAGDAHRLLLPARDAT----GTTVLVD-AAATVI--------EQPVLDET
Mb3594|M.bovis_AF2122/97            NGDIAD-IVVAATS------GQLTRWTRFSAQP----------VATMDPT
Rv3564|M.tuberculosis_H37Rv         NGDIAD-IVVAATS------GQLTRWTRFSAQP----------VATMDPT
MMAR_2861|M.marinum_M               HGHVAD-LFVVPAESD----GAVILYVVDAAAPGVAV----VGLPSFDIT
MUL_2893|M.ulcerans_Agy99           HGHVAD-LFVVPAESD----GAVILYVVDAAAPGVAV----VGLPSFDIT
MAV_2570|M.avium_104                GGSVADDLVVVAIDED----GEPAVFLLDPTIDSVVA----EAERVLDRT
MAB_3123|M.abscessus_ATCC_1997      DGATADVILVLADTD-----SGPSLFAVDGDAPGVDR----HSLATLDMT
MLBr_00737|M.leprae_Br4923          NGGKSTWYTVMAVTDPDKGANGISAFIVHKDDEGFSIGPKEKKLGIKGSP
                                     .  :    :                                     . .

Mflv_1795|M.gilvum_PYR-GCK          RRLATVAADSATVVDILTFDGNPADAVNALRHRAEIAVACDSLGVAEQML
Mvan_4955|M.vanbaalenii_PYR-1       RQLATVTAEAAEIAELLTLAGDPAS----VRHRAEVAIACDSLGLAEQML
TH_2777|M.thermoresistible__bu      RRLAVVCAEDSGVEAVWRFAGDPRAAARRLADRAAVAVAIDSLGLAEAML
MSMEG_5618|M.smegmatis_MC2_155      RRLAIVEADGAEARDVWPLE-DPHA----LARRAALAVACDSLGIAAAML
Mb3594|M.bovis_AF2122/97            RRLARLQSE--ETEPLCPDPG--------IADTAAILLAAEQIGAAERCL
Rv3564|M.tuberculosis_H37Rv         RRLARLQSE--ETEPLCPDPG--------IADTAAILLAAEQIGAAERCL
MMAR_2861|M.marinum_M               RPVAKLRLVRAPAEALAASSAD--E-VARLLDVARVLLAAEMLGGAEACL
MUL_2893|M.ulcerans_Agy99           RPVAKLRLVRAPAEALAASSAD--E-VARLLDVARVLLAAEMLGGAEACL
MAV_2570|M.avium_104                RPMATITLSSAPALRLSGDAPLGDV-VDRNVDIALAVLSAEQVGACERVL
MAB_3123|M.abscessus_ATCC_1997      RRQANIHFNSAPARLIGAQGRGAEA-VATALDVAATVLAAEQAGIAAHML
MLBr_00737|M.leprae_Br4923          TTELYFDKCRIPGDRIIGEPGTGFKTALATLDHTRPTIGAQAVGIAQGAL
                                         .         :                 :   :. :  * .   *

Mflv_1795|M.gilvum_PYR-GCK          SDTVDYVKVRHQFGRPIGSFQAVKHACADMLVAVEVSRQLVADAVDVLAG
Mvan_4955|M.vanbaalenii_PYR-1       AATVDYVLVRHQFGRPIGSFQAVKHACADMLVAIEVSRRLVSDAVGVLAE
TH_2777|M.thermoresistible__bu      SATVSYAKVRHQFGRPIGSFQAVKHACADMQVQITVARQLVGRAVAALCD
MSMEG_5618|M.smegmatis_MC2_155      DATVSYASMRQQFGRPIGSFQAVKHACADMLVQVTAARQLIAGAIS----
Mb3594|M.bovis_AF2122/97            QLTVEYAKSRVQFGRPIGSFQALKHRMADLYVTIAAARAVV--ADACHAP
Rv3564|M.tuberculosis_H37Rv         QLTVEYAKSRVQFGRPIGSFQALKHRMADLYVTIAAARAVV--ADACHAP
MMAR_2861|M.marinum_M               DLAIEYACSRKQFDRPIGSFQAVKHRCADMMIEIDATRAAVMFAQLCAAG
MUL_2893|M.ulcerans_Agy99           DLAIEYACSRKQFDRPIGSFQAVKHRCADMMIEIDATRAAVMFAQLCAAG
MAV_2570|M.avium_104                EIATDYARTREQFGRQIGSFQAIKHKCADMLVDLEWARSASQAALEALDD
MAB_3123|M.abscessus_ATCC_1997      DVTTEYAKSRIQFGRIIGSFQAVKHRLADMAAATGNVRGAAYHAAWSHDH
MLBr_00737|M.leprae_Br4923          DAAIVYTKDRKQFGESISTFQSIQFMLADMAMKVEAARLIVYAAAARAER
                                      :  *.  * **.. *.:**:::.  **:       *     *      

Mflv_1795|M.gilvum_PYR-GCK          --GGDAAIP---AAMAKSYVCAAAVEVAGKAMQLHGGIGYTWESGIHTYL
Mvan_4955|M.vanbaalenii_PYR-1       --GGDAATQ---AAMAKSHACSAAVDVAGKAMQLHGGIGYTWESGIHVYL
TH_2777|M.thermoresistible__bu      PDSDDTAAA---AAMAKSFVCSAAVEVVGKAMQLHGGIGYTWESGVHVYL
MSMEG_5618|M.smegmatis_MC2_155      ---APDAHT---VAKAKSYATEAAVGVAGKAMQLHGGIGYTWESGVHTYL
Mb3594|M.bovis_AF2122/97            TPTNAATAR-----LAASEALST---AAAEGIQLHGGIAITWEHDMHLYF
Rv3564|M.tuberculosis_H37Rv         TPTNAATAR-----LAASEALST---AAAEGIQLHGGIAITWEHDMHLYF
MMAR_2861|M.marinum_M               GDELHATAP-----LAKAQAADTYVLCAGSAIQVHGGIAFTWEHDLHLYF
MUL_2893|M.ulcerans_Agy99           GDELHATAP-----LAKAQAAGTYVLCAGSAIQVHGGIAFTWEHDLHLYF
MAV_2570|M.avium_104                PDSAAAGEAGWRASMAKAVCSEALRNATKANVQIHGGIGFTWEDSAHLYF
MAB_3123|M.abscessus_ATCC_1997      PSLDDPALAT---SIAQQVASAGAVEVTAKAIQSHGGIGFTWEHPAHLYY
MLBr_00737|M.leprae_Br4923          GEPDLGFIS----AASKCFASDIAMEVTTDAVQLFGGAGYTSDFPVERFM
                                                   :           .   :* .** . * :   . : 

Mflv_1795|M.gilvum_PYR-GCK          KRATLNRSLFGSPAAQRRRLSQRYH-------------------------
Mvan_4955|M.vanbaalenii_PYR-1       KRATLNRALFGSPAAQRKRLSQRYSKGI----------------------
TH_2777|M.thermoresistible__bu      KRATLNRALYGSPAAHRSQLVSRYR-------------------------
MSMEG_5618|M.smegmatis_MC2_155      KRAALNRSLFGSPREHRTMLSARYRSAPG---------------------
Mb3594|M.bovis_AF2122/97            KRAHGSAQLLESPREVLRRLESEVWESP----------------------
Rv3564|M.tuberculosis_H37Rv         KRAHGSAQLLESPREVLRRLESEVWESP----------------------
MMAR_2861|M.marinum_M               RRAKTTEALFGSSAHHRSLLADRVGL------------------------
MUL_2893|M.ulcerans_Agy99           RRAKTTEALFGSSAHHRSLLADRVGL------------------------
MAV_2570|M.avium_104                RRARTDEVLLGAPGQHWDRLSTLDPSTQPPASPEVTKELNDVDALRAEIR
MAB_3123|M.abscessus_ATCC_1997      KRAVSNSALFGGRAVHAERIAKEVIDA-----------------------
MLBr_00737|M.leprae_Br4923          RDAKITQIYEGTNQIQRVVMSRALLR------------------------
                                    : *                :                              

Mflv_1795|M.gilvum_PYR-GCK          --------------------------------------------------
Mvan_4955|M.vanbaalenii_PYR-1       --------------------------------------------------
TH_2777|M.thermoresistible__bu      --------------------------------------------------
MSMEG_5618|M.smegmatis_MC2_155      --------------------------------------------------
Mb3594|M.bovis_AF2122/97            --------------------------------------------------
Rv3564|M.tuberculosis_H37Rv         --------------------------------------------------
MMAR_2861|M.marinum_M               --------------------------------------------------
MUL_2893|M.ulcerans_Agy99           --------------------------------------------------
MAV_2570|M.avium_104                SFLDNAPRPAGLRNYGPTPTADDVEAGRVWHRYLADHGYACLHWPREFGG
MAB_3123|M.abscessus_ATCC_1997      --------------------------------------------------
MLBr_00737|M.leprae_Br4923          --------------------------------------------------
                                                                                      

Mflv_1795|M.gilvum_PYR-GCK          --------------------------------------------------
Mvan_4955|M.vanbaalenii_PYR-1       --------------------------------------------------
TH_2777|M.thermoresistible__bu      --------------------------------------------------
MSMEG_5618|M.smegmatis_MC2_155      --------------------------------------------------
Mb3594|M.bovis_AF2122/97            --------------------------------------------------
Rv3564|M.tuberculosis_H37Rv         --------------------------------------------------
MMAR_2861|M.marinum_M               --------------------------------------------------
MUL_2893|M.ulcerans_Agy99           --------------------------------------------------
MAV_2570|M.avium_104                AAATVTYQAVFAEECARAEVPRQVNITGADLVGPVLIKFGSQEQKDRYLE
MAB_3123|M.abscessus_ATCC_1997      --------------------------------------------------
MLBr_00737|M.leprae_Br4923          --------------------------------------------------
                                                                                      

Mflv_1795|M.gilvum_PYR-GCK          --------------------------------------------------
Mvan_4955|M.vanbaalenii_PYR-1       --------------------------------------------------
TH_2777|M.thermoresistible__bu      --------------------------------------------------
MSMEG_5618|M.smegmatis_MC2_155      --------------------------------------------------
Mb3594|M.bovis_AF2122/97            --------------------------------------------------
Rv3564|M.tuberculosis_H37Rv         --------------------------------------------------
MMAR_2861|M.marinum_M               --------------------------------------------------
MUL_2893|M.ulcerans_Agy99           --------------------------------------------------
MAV_2570|M.avium_104                PIRLGDDVWCQLFSEPGAGSDLAGVRTRAERTTTGWRIDGQKVWSSAAAS
MAB_3123|M.abscessus_ATCC_1997      --------------------------------------------------
MLBr_00737|M.leprae_Br4923          --------------------------------------------------
                                                                                      

Mflv_1795|M.gilvum_PYR-GCK          --------------------------------------------------
Mvan_4955|M.vanbaalenii_PYR-1       --------------------------------------------------
TH_2777|M.thermoresistible__bu      --------------------------------------------------
MSMEG_5618|M.smegmatis_MC2_155      --------------------------------------------------
Mb3594|M.bovis_AF2122/97            --------------------------------------------------
Rv3564|M.tuberculosis_H37Rv         --------------------------------------------------
MMAR_2861|M.marinum_M               --------------------------------------------------
MUL_2893|M.ulcerans_Agy99           --------------------------------------------------
MAV_2570|M.avium_104                ARFGLLLARTGPDKHRDLSMFVVPMDIPGVTVRPLTQMDGESKFNEVFFD
MAB_3123|M.abscessus_ATCC_1997      --------------------------------------------------
MLBr_00737|M.leprae_Br4923          --------------------------------------------------
                                                                                      

Mflv_1795|M.gilvum_PYR-GCK          --------------------------------------------------
Mvan_4955|M.vanbaalenii_PYR-1       --------------------------------------------------
TH_2777|M.thermoresistible__bu      --------------------------------------------------
MSMEG_5618|M.smegmatis_MC2_155      --------------------------------------------------
Mb3594|M.bovis_AF2122/97            --------------------------------------------------
Rv3564|M.tuberculosis_H37Rv         --------------------------------------------------
MMAR_2861|M.marinum_M               --------------------------------------------------
MUL_2893|M.ulcerans_Agy99           --------------------------------------------------
MAV_2570|M.avium_104                GAELDEDALIGEVGQGWTVAMVTLGRERLTLGSQAVSMFRLHERMVDAAR
MAB_3123|M.abscessus_ATCC_1997      --------------------------------------------------
MLBr_00737|M.leprae_Br4923          --------------------------------------------------
                                                                                      

Mflv_1795|M.gilvum_PYR-GCK          --------------------------------------------------
Mvan_4955|M.vanbaalenii_PYR-1       --------------------------------------------------
TH_2777|M.thermoresistible__bu      --------------------------------------------------
MSMEG_5618|M.smegmatis_MC2_155      --------------------------------------------------
Mb3594|M.bovis_AF2122/97            --------------------------------------------------
Rv3564|M.tuberculosis_H37Rv         --------------------------------------------------
MMAR_2861|M.marinum_M               --------------------------------------------------
MUL_2893|M.ulcerans_Agy99           --------------------------------------------------
MAV_2570|M.avium_104                DHDLLDPVLSRSMTRLWARMWLLRFTWQRAIDSGDLTSPAFSVLKLMTSE
MAB_3123|M.abscessus_ATCC_1997      --------------------------------------------------
MLBr_00737|M.leprae_Br4923          --------------------------------------------------
                                                                                      

Mflv_1795|M.gilvum_PYR-GCK          --------------------------------------------------
Mvan_4955|M.vanbaalenii_PYR-1       --------------------------------------------------
TH_2777|M.thermoresistible__bu      --------------------------------------------------
MSMEG_5618|M.smegmatis_MC2_155      --------------------------------------------------
Mb3594|M.bovis_AF2122/97            --------------------------------------------------
Rv3564|M.tuberculosis_H37Rv         --------------------------------------------------
MMAR_2861|M.marinum_M               --------------------------------------------------
MUL_2893|M.ulcerans_Agy99           --------------------------------------------------
MAV_2570|M.avium_104                TDQDLGDMATEVLGTDACTDPEEDGLVHHMLIGRAQTILGGTSEIQRNIL
MAB_3123|M.abscessus_ATCC_1997      --------------------------------------------------
MLBr_00737|M.leprae_Br4923          --------------------------------------------------
                                                                                      

Mflv_1795|M.gilvum_PYR-GCK          ------------
Mvan_4955|M.vanbaalenii_PYR-1       ------------
TH_2777|M.thermoresistible__bu      ------------
MSMEG_5618|M.smegmatis_MC2_155      ------------
Mb3594|M.bovis_AF2122/97            ------------
Rv3564|M.tuberculosis_H37Rv         ------------
MMAR_2861|M.marinum_M               ------------
MUL_2893|M.ulcerans_Agy99           ------------
MAV_2570|M.avium_104                GERVLGLPKEPR
MAB_3123|M.abscessus_ATCC_1997      ------------
MLBr_00737|M.leprae_Br4923          ------------