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VYIDYEVSDRIATITLNRPEAANAQNPELLDELDAAWTRAAEDNDVSVIVLRANGKHFSAGHDLRGGGPV PDKITLEFIIQHEAKRYLEYTLRWRNVPKPSIAAVQGRCISGGLLLCWPCDLIVAADDAQFSDPVVLMGI GGVEYHGHTWELGPRKAKEILFTGRAMTADEVAATGMVNKVVPRAELDAETRALAEQIAKMPPFALRQAK RAVNQTLDVQGFYAAIQSVFDVHQTGHGNALSVGGWPVLVNLEEMKANIK
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. gilvum PYR-GCK | Mflv_2433 | - | - | 100% (260) | enoyl-CoA hydratase |
| M. gilvum PYR-GCK | Mflv_1568 | - | 6e-54 | 46.90% (258) | enoyl-CoA hydratase |
| M. gilvum PYR-GCK | Mflv_2036 | - | 2e-27 | 34.58% (214) | enoyl-CoA hydratase |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb1970c | echA13 | 4e-53 | 46.21% (264) | enoyl-CoA hydratase |
| M. tuberculosis H37Rv | Rv1935c | echA13 | 4e-53 | 46.21% (264) | enoyl-CoA hydratase |
| M. leprae Br4923 | MLBr_02402 | - | 1e-26 | 35.21% (213) | enoyl-CoA hydratase |
| M. abscessus ATCC 19977 | MAB_2058 | - | 2e-26 | 37.39% (230) | enoyl-CoA dehydratase/isomerase |
| M. marinum M | MMAR_2863 | echA13 | 7e-54 | 45.83% (264) | enoyl-CoA hydratase EchA13 |
| M. avium 104 | MAV_0670 | - | 1e-53 | 46.33% (259) | enoyl-CoA hydratase |
| M. smegmatis MC2 155 | MSMEG_4846 | - | 1e-135 | 88.46% (260) | enoyl-CoA hydratase |
| M. thermoresistible (build 8) | TH_2728 | - | 1e-140 | 91.15% (260) | PUTATIVE Enoyl-CoA hydratase/isomerase |
| M. ulcerans Agy99 | MUL_0210 | echA8 | 3e-28 | 35.02% (217) | enoyl-CoA hydratase |
| M. vanbaalenii PYR-1 | Mvan_4219 | - | 1e-146 | 96.54% (260) | enoyl-CoA hydratase |
CLUSTAL 2.0.9 multiple sequence alignment
Mb1970c|M.bovis_AF2122/97 MFVGRVGPVDRRSDGERSRRPREFEYIRYETIDDGRIAAITLDRPKQRNA
Rv1935c|M.tuberculosis_H37Rv MFVGRVGPVDRRSDGERSRRPREFEYIRYETIDDGRIAAITLDRPKQRNA
MMAR_2863|M.marinum_M MNVAGVSPVDRRSNGERAAP--DFTYVRYETIDDGRIATITLNRPKQRNA
MAV_0670|M.avium_104 MTLSEQAGAQP---GARPAE----ELVTYETLDEGRIARIWLNRPDAHNA
Mflv_2433|M.gilvum_PYR-GCK ------------------------MYIDYEVSD--RIATITLNRPEAANA
Mvan_4219|M.vanbaalenii_PYR-1 ------------------------MYIDYDVTD--RIATITLNRPEAANA
TH_2728|M.thermoresistible__bu ------------------------MYIDYDVSD--RIATITLNRPEAANA
MSMEG_4846|M.smegmatis_MC2_155 ------------------------MYIDYGVAD--SIATITLNRPEAANA
MLBr_02402|M.leprae_Br4923 ---------------------MKYDTILVDGYQ--RVGIITLNRPQALNA
MUL_0210|M.ulcerans_Agy99 ---------------------MSYETILVERDQ--RVGIITLNRPQALNA
MAB_2058|M.abscessus_ATCC_1997 ---------------------MAEQPIRYEVVD--SVAWLTINRPEARNA
: : :. : ::**. **
Mb1970c|M.bovis_AF2122/97 QTRGMLVELGAAFELAEADDTVRVVILRAA-GPAFSAGHDLGSADDIRER
Rv1935c|M.tuberculosis_H37Rv QTRGMLVELGAAFELAEADDTVRVVILRAA-GPAFSAGHDLGSADDIRER
MMAR_2863|M.marinum_M QTRGMLVELGAAFELAEADDTVRVVILRGE-GPAFSAGHDLGSADDVRER
MAV_0670|M.avium_104 QSRGLLVQLDEAFVRAEADDAVRVVILAAR-GKNFSAGHDLGSELALAER
Mflv_2433|M.gilvum_PYR-GCK QNPELLDELDAAWTRAAEDNDVSVIVLRAN-GKHFSAGHDLRGGGPVPDK
Mvan_4219|M.vanbaalenii_PYR-1 QNPELLDELDAAWTRAAEDNEVSVIVLRAN-GKHFSAGHDLRGGGPVPDK
TH_2728|M.thermoresistible__bu QNPELLDELDAAWTRAAEDNDVSVIVLRAN-GKHFSAGHDLRGGGPVPDK
MSMEG_4846|M.smegmatis_MC2_155 QNPELLDELDAAWTRAAEDNEVKVIILRAN-GKHFSAGHDLRGGGEVPEK
MLBr_02402|M.leprae_Br4923 LNSQMMNEITNAAKELDIDPDVGAILITGS-PKVFAAGADIKEMASLTFT
MUL_0210|M.ulcerans_Agy99 LNSQVMNEVTSAAAELDNDPGIGAIIITGS-AKAFAAGADIKEMADLTFS
MAB_2058|M.abscessus_ATCC_1997 LNNAVRTGLIDAVLRFNDDDAAKVLVLTGVGDKAFCAGGDLKEMAQNALK
. : : * * .::: . *.** *:
Mb1970c|M.bovis_AF2122/97 SPGPDQHPSYRCNGATFGGVESRN-RQEWHYYFENTKRWRNLRKITIAQV
Rv1935c|M.tuberculosis_H37Rv SPGPDQHPSYRCNGATFGGVESRN-RQEWHYYFENTKRWRNLRKITIAQV
MMAR_2863|M.marinum_M APGPDQHPTYQCNGGTYGGVESRN-RQEWHYYFENTKRWRNLRKITVAQV
MAV_0670|M.avium_104 QPGPGQHPTFRFNGATRDPIAEKTYLQEWHYFFQNTCRWRDLRKITIAQV
Mflv_2433|M.gilvum_PYR-GCK IT------------------LEFIIQHEAKRYLEYTLRWRNVPKPSIAAV
Mvan_4219|M.vanbaalenii_PYR-1 IT------------------LEFIIAHEAKRYLEYTLRWRNVPKPSIAAV
TH_2728|M.thermoresistible__bu LT------------------LEFIYAHESRRYLEYSLRWRNVPKPSIAAV
MSMEG_4846|M.smegmatis_MC2_155 IS------------------LEFIIQHEARRYLDYTLRWRNVPKPSIAAV
MLBr_02402|M.leprae_Br4923 DAFD-------------------------ADFFSAWGKLAAVRTPMIAAV
MUL_0210|M.ulcerans_Agy99 EAFD-------------------------ADFFAAWGKLAAVRTPTIAAV
MAB_2058|M.abscessus_ATCC_1997 VPP--------------------------KDFAPQFGRNIDVAKPTIAAV
. : : : . :* *
Mb1970c|M.bovis_AF2122/97 HGAVLSAGLMLAWCCDLIVASEDTVFADVVGTRLGMCGVEYFG-HPWEFG
Rv1935c|M.tuberculosis_H37Rv HGAVLSAGLMLAWCCDLIVASEDTVFADVVGTRLGMCGVEYFG-HPWEFG
MMAR_2863|M.marinum_M HGTVLSAGLMLAWCCDLIVAADDTVFADVVGTRLGMCGVEYFG-HPWEFG
MAV_0670|M.avium_104 QGNAISAGLMLIWACDLIVAADNAKFSDVVGVRMGMPGVEYYA-HPWEFG
Mflv_2433|M.gilvum_PYR-GCK QGRCISGGLLLCWPCDLIVAADDAQFSDPV-VLMGIGGVEYHG-HTWELG
Mvan_4219|M.vanbaalenii_PYR-1 QGRCISGGLLLCWPCDLIVAADDAQFSDPV-VLMGIGGVEYHG-HTWELG
TH_2728|M.thermoresistible__bu QGRCISGGLLLCWPCDLIIAAEDALFSDPV-VLMGIGGVEYHG-HTWELG
MSMEG_4846|M.smegmatis_MC2_155 QGRCISGGLLLCWPCDLILASDDALFSDPV-ALMGIGGVEYHG-HTWELG
MLBr_02402|M.leprae_Br4923 AGYALGGGCELAMMCDLLIAADTAKFGQPEIKLGVLPGMGGSQRLTRAIG
MUL_0210|M.ulcerans_Agy99 AGYALGGGCEVAMMCDLIIAADTAKFGQPEIKLGVLPGMGGSQRLTRAIG
MAB_2058|M.abscessus_ATCC_1997 NGVAFAGGFLLAQQCDLVVAAEHATFAVSEVKVG--RGSPWATPLSWLVP
* :..* : ***::*:: : *. * . .
Mb1970c|M.bovis_AF2122/97 PRKTKELLLTGDCIGADEAHALGMVSKVFPADELATSTIEFARRIAKVPT
Rv1935c|M.tuberculosis_H37Rv PRKTKELLLTGDCIGADEAHALGMVSKVFPADELATSTIEFARRIAKVPT
MMAR_2863|M.marinum_M PRKAKELLLTGDSIGADEAHALGMVSKVFPGEDLADSAIEFARRIAKLPT
MAV_0670|M.avium_104 PRKAKELLLTGDALDADEAYRLGMVSKVFPADELADKTLEFARRIAERPT
Mflv_2433|M.gilvum_PYR-GCK PRKAKEILFTGRAMTADEVAATGMVNKVVPRAELDAETRALAEQIAKMPP
Mvan_4219|M.vanbaalenii_PYR-1 PRKAKEILFTGRAMTAEEVAATGMVNRVVPRDQLDAETRTLAEQIAKMPP
TH_2728|M.thermoresistible__bu PRKAKEILFTGRAMTAEEVAQTGMVNRVVPRDRLDAETRALAGEIAKMPP
MSMEG_4846|M.smegmatis_MC2_155 PRKAKEILFTGRALTAEEAERTGMVNRVVARDELDAQTRELAEQIATMPP
MLBr_02402|M.leprae_Br4923 KAKAMDLILTGRTIDAAEAERSGLVSRVVLADDLLPEAKAVATTISQMSR
MUL_0210|M.ulcerans_Agy99 KAKAMDLILTGRTIDAAEAERSGLVSRVVPADDLLTEAKAVATTISQMSR
MAB_2058|M.abscessus_ATCC_1997 PRVAMQILLTGDPITAARAHQVGLVNEVVPADQLRERTQQLALSIAANAP
: ::::** : * .. *:*..*. * : .* *: .
Mb1970c|M.bovis_AF2122/97 MAALLIKESVNQTVDAMGFSAALDGCFKIHQLNHAHWGEVTGGKLSYGTV
Rv1935c|M.tuberculosis_H37Rv MAALLIKESVNQTVDAMGFSAALDGCFKIHQLNHAHWGEVTGGKLSYGTV
MMAR_2863|M.marinum_M MAALLIKESVNQTVDAMGFTTALDGCFKIHQLNHAHWAEVTGGKLCYGTV
MAV_0670|M.avium_104 MAALLIKDSVNAASDAMGFTEALRHAFHIHELGHAHWAAHNENRYPVG-L
Mflv_2433|M.gilvum_PYR-GCK FALRQAKRAVNQTLDVQGFYAAIQSVFDVHQTGHGNALSVGG-----WPV
Mvan_4219|M.vanbaalenii_PYR-1 FALRQAKRAVNQTLDVQGFYAAIQSVFDVHQTGHGNALSVGG-----WPV
TH_2728|M.thermoresistible__bu FALRQAKRAVNQTLDVQGFYAAIQSVFDIHQTGHGNAMSVSG-----WPV
MSMEG_4846|M.smegmatis_MC2_155 FALRQAKRAVNQTLDVQGFYAAIQSVFDIHQTGHGNALSVSG-----WPV
MLBr_02402|M.leprae_Br4923 SATRMAKEAVNRSFEST-LAEGLLHERRLFHSTFVTDDQSEG--------
MUL_0210|M.ulcerans_Agy99 SAARMAKEAVNRTFEAT-LAEGLLYERRLIHSAFATADQSEG--------
MAB_2058|M.abscessus_ATCC_1997 LSVLASKRTVYLSAQHH-LAAAYDLADEIWEPVYLSDDAQEG--------
: * :* : : : . : . .
Mb1970c|M.bovis_AF2122/97 EYGLEDWRAAPQIRPAIKQRP
Rv1935c|M.tuberculosis_H37Rv EYGLEDWRAAPQIRPAIKQRP
MMAR_2863|M.marinum_M EYGLDDWRAAPEILPATKRRP
MAV_0670|M.avium_104 PPDVEDWRNAKPTRLARRDTP
Mflv_2433|M.gilvum_PYR-GCK LVNLEEMKANIK---------
Mvan_4219|M.vanbaalenii_PYR-1 LVNLEEMKANIK---------
TH_2728|M.thermoresistible__bu LVDIEEMKANIK---------
MSMEG_4846|M.smegmatis_MC2_155 LVDIEEMKANIK---------
MLBr_02402|M.leprae_Br4923 MAAFIEKRAPQFTHR------
MUL_0210|M.ulcerans_Agy99 MAAFIEKRPPNFTHR------
MAB_2058|M.abscessus_ATCC_1997 PAAFREKRAPQWKGH------
. : :