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MTRTDQDSWDLASSVGATATMVAAARALASTGERPIINDPFAAPLVRAVGLDFFRRLVDGEVAPADPQRG ERDLQLETDSIAVRTRFFDDFFTGAARDGIRQSVILAAGLDARAYRLDWPAGAVVYEVDQPKVVEFKTNT MAALDARPAAQLRTVSIDLREDWPEALRANGFDVTQATSWSAEGLLMYLPPEAQDRLFDNITALSAPGSR LATEYHPDATGTTMAQRAQEFNDRWARVGCDIDLSGLFFDGERSNVVEYLTGRGWRVSARPRRDLFDDYG LAYPEDDETAQFPNIVAVSAELG
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. avium 104 | MAV_4435 | - | - | 100% (303) | methyltransferase, putative, family protein |
| M. avium 104 | MAV_4442 | - | 4e-96 | 59.14% (301) | methyltransferase, putative, family protein |
| M. avium 104 | MAV_0778 | - | 9e-91 | 57.10% (303) | methyltransferase, putative, family protein |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb0853 | - | 4e-86 | 54.28% (304) | hypothetical protein Mb0853 |
| M. gilvum PYR-GCK | Mflv_5025 | - | 6e-89 | 57.57% (304) | putative methyltransferase |
| M. tuberculosis H37Rv | Rv0830 | - | 5e-86 | 54.28% (304) | hypothetical protein Rv0830 |
| M. leprae Br4923 | MLBr_02640 | - | 9e-57 | 45.74% (282) | hypothetical protein MLBr_02640 |
| M. abscessus ATCC 19977 | MAB_3787 | - | 1e-80 | 52.77% (307) | hypothetical protein MAB_3787 |
| M. marinum M | MMAR_1068 | - | 1e-124 | 73.27% (303) | O-methyltransferase |
| M. smegmatis MC2 155 | MSMEG_1481 | - | 1e-99 | 60.86% (304) | methyltransferase |
| M. thermoresistible (build 8) | TH_2706 | - | 5e-98 | 60.13% (301) | PUTATIVE putative methyltransferase |
| M. ulcerans Agy99 | MUL_0817 | - | 2e-89 | 56.21% (290) | O-methyltransferase |
| M. vanbaalenii PYR-1 | Mvan_1344 | - | 7e-88 | 56.86% (306) | putative methyltransferase |
CLUSTAL 2.0.9 multiple sequence alignment
MAV_4435|M.avium_104 MTR-TDQDSWDLASSVGATATMVAAARALASTGERPIINDPFAAPLVRAV
MMAR_1068|M.marinum_M MTR-TDQDSWDLASSVGATATMVAAARALASAEANPIIDDPFAAPLVRAV
MSMEG_1481|M.smegmatis_MC2_155 MAR-TDTDSWDLASSVGATATMVAAARAIASTEPNALIDDPYAADLVRKV
TH_2706|M.thermoresistible__bu MAR-SESDTWDLTSGVGVTATMVAAARALASREPEPLIDDPFAAPLVRAV
MUL_0817|M.ulcerans_Agy99 MNRRTDADSWDPASSVGATATMVAASRARASRGPDALLDDRLAGPLVRAV
Mflv_5025|M.gilvum_PYR-GCK MAR-TPDDSWDLASSVGATATMVAAGRAVASADPDPLINDPYAEPLVRAV
Mvan_1344|M.vanbaalenii_PYR-1 MAR-TADDSWDPASSVGATATMVAAGRAAASADPDPLINDPYAEPLVRAV
MAB_3787|M.abscessus_ATCC_1997 MAR-TDDDSWDLASSVGATATMVAAQRALASHVPNPLINDPYAEPLVRAV
Mb0853|M.bovis_AF2122/97 MVR-ADRDRWDLATSVGATATMVAAQRALAADPRYALIDDPYAAPLVRAV
Rv0830|M.tuberculosis_H37Rv MVR-ADRDRWDLATSVGATATMVAAQRALAADPRYALIDDPYAAPLVRAV
MLBr_02640|M.leprae_Br4923 -MR-THDDTWDIKTSVGTTAVMVAAARAAETDRPDALIRDPYAKLLVTNT
* : * ** :.**.**.**** ** : .:: * * ** .
MAV_4435|M.avium_104 GL-DFFRRLVDGEVAPA--DPQRGERDLQ-LETDSIAVRTRFFDDFFTGA
MMAR_1068|M.marinum_M GL-DFFTRLAEGEID----HDEQAQRDRQ-LVADSIAVRTRFFDDFFLDA
MSMEG_1481|M.smegmatis_MC2_155 GL-EFFTKLVDGDIALD--GD---DAAAAGLMVSMMAVRTRFFDDFFCDA
TH_2706|M.thermoresistible__bu GV-EFFTRLVDGDLELP--ADTAEERAAAQVLTEVMAVRTRFFDDFFTDA
MUL_0817|M.ulcerans_Agy99 GL-QPLVRMIDGDTAVD--DPPSSPRSLN----EQIAVRTRYFDDFFTAA
Mflv_5025|M.gilvum_PYR-GCK GL-DFFTRMLDGELDLSVFPDSSPE--RAQAMIDGMAVRTRFFDDCCLAA
Mvan_1344|M.vanbaalenii_PYR-1 GL-SFFTKMLDGELDLSQFADGSPE--RVQAMIDGMAVRTRFFDDCCGTS
MAB_3787|M.abscessus_ATCC_1997 GI-EYFTKLASGAFDPEQMAGLVQLGITADGMANGMASRTWYYDTAFESS
Mb0853|M.bovis_AF2122/97 GM-DVYTRLVDWQIPVEGDSEFDPQR-----MATGMACRTRFFDQFFLDA
Rv0830|M.tuberculosis_H37Rv GM-DVYTRLVDWQIPVEGDSEFDPQR-----MATGMACRTRFFDQFFLDA
MLBr_02640|M.leprae_Br4923 GAGALWEAMLDPSMVAKVEAIDAEAAAMVEHMRSYQAVRTNFFDTYFNNA
* : . * ** ::* :
MAV_4435|M.avium_104 ARDGIRQSVILAAGLDARAYRLDWPAGAVVYEVDQPKVVEFKTNTMAALD
MMAR_1068|M.marinum_M ARRGVRQSVILAAGLDARAYRLPWPSGSVVYEVDQPDVIDFKDTTMSALG
MSMEG_1481|M.smegmatis_MC2_155 AGAGIRQSVILAAGLDSRAYRLGWPAGTVVYEIDQPRVIEAKTAAMAEIG
TH_2706|M.thermoresistible__bu TRVGARQAVILASGLDARAYRLTWPDGTVVYEIDQPEVIAFKTRTLAELG
MUL_0817|M.ulcerans_Agy99 GAGGIRQAVILASGLDTRAYRLNWPSGMTVYEIDQPQVIEFKTRTLAEFG
Mflv_5025|M.gilvum_PYR-GCK ASAGVRQVVILAAGLDARTYRLPWPDGTVVYELDQPDVIAFKTQTLRNLG
Mvan_1344|M.vanbaalenii_PYR-1 TTAGITQVVILASGLDARAYRLGWPAGTVVYELDQPAVIEFKTRTLAGLG
MAB_3787|M.abscessus_ATCC_1997 TAAGVRQAVILASGLDTRAYRLTWPAGTTVYELDQPEVITFKTDTLAELG
Mb0853|M.bovis_AF2122/97 THSGIGQFVILASGLDARAYRLAWPVGSIVYEVDMPEVIEFKTATLSDLG
Rv0830|M.tuberculosis_H37Rv THSGIGQFVILASGLDARAYRLAWPVGSIVYEVDMPEVIEFKTATLSDLG
MLBr_02640|M.leprae_Br4923 VIDGIRQFVILASGLDSRAYRLDWPTGTTVYEIDQPKVLAYKSTTLAEHG
* * ****:***:*:*** ** * ***:* * *: * :: .
MAV_4435|M.avium_104 ARPAAQLRTVSIDLREDWPEALRANGFDVTQATSWSAEGLLMYLPPEAQD
MMAR_1068|M.marinum_M AVPTATRRTVRVDLRDDWPAALRHNGFDTTQPTAWSAEGLLMYLPPDAQD
MSMEG_1481|M.smegmatis_MC2_155 ASPTAERRTVAVDLRDDWPAALRAAGFDAATPTAWIAEGLLVYLPPEAQD
TH_2706|M.thermoresistible__bu APPTAPHRPVAVDLRDDWPAALTAAGFDPTVATAWSAEGLLRYLPPDAQD
MUL_0817|M.ulcerans_Agy99 ALPCPDHRPIGIDLREDWPSALRQRGFDAGQPTAWIAEGLLVYLPPEAQD
Mflv_5025|M.gilvum_PYR-GCK AEPAATQRPVPVDLREDWPAALRAAGFDATRPTAWLAEGLLIYLPPEAQD
Mvan_1344|M.vanbaalenii_PYR-1 AHPTATHRPVPIDLREDWPAALHAAGFDASRPTAWLAEGLLIYLPPEAQD
MAB_3787|M.abscessus_ATCC_1997 ASPSAERRTVAIDLREDWPAALQAAGFDPEQPTVWSAEGLLIYLPPEAQD
Mb0853|M.bovis_AF2122/97 AEPATERRTVAVDLRDDWATALQTAGFDPKVPAAWSAEGLLVYLPVEAQD
Rv0830|M.tuberculosis_H37Rv AEPATERRTVAVDLRDDWATALQTAGFDPKVPAAWSAEGLLVYLPVEAQD
MLBr_02640|M.leprae_Br4923 VTPTADRREVPIDLRQDWPPALRSAGFDPSARTAWLAEGLLMYLPATAQD
. * . * : :***:**. ** *** : * ***** *** ***
MAV_4435|M.avium_104 RLFDNITALSAPGSRLATEYHPDATGTTMAQRAQEFNDRWARVGCD--ID
MMAR_1068|M.marinum_M RLFDAISGLSAPGSRLATEYHPDP-GSTMAERAQQFNQRWVRLGCD--ID
MSMEG_1481|M.smegmatis_MC2_155 RLFDNITALSARGSRLATEYHPDI-TSTLRGRGQAMSERWRDHGFD--VD
TH_2706|M.thermoresistible__bu RLFDHITDLSAPGSRLATEDHPGP-GAGLGEKADELGRRWREHGFE--VQ
MUL_0817|M.ulcerans_Agy99 RLFDNIAELSTPRSQVATEHFPDP-NGFSGPRAQRLSERWHRMGMD--LD
Mflv_5025|M.gilvum_PYR-GCK ALFDTVTALSAPGSTLATEYVPGIVDFDG-AKARALSEPLREHGLD--ID
Mvan_1344|M.vanbaalenii_PYR-1 QLFDRITALSAPGSTIATEYAPGIIDFDD-EKARAMSAPMREMGLD--ID
MAB_3787|M.abscessus_ATCC_1997 RLFASITELSAPGSRLVCEQVPGLETADF-SKARELTRQFAGETLD--LD
Mb0853|M.bovis_AF2122/97 ALFDNITALSAPGSRLAFEFVPDT-AIFADERWRNYHNRMSELGFD--ID
Rv0830|M.tuberculosis_H37Rv ALFDNITALSAPGSRLAFEFVPDT-AIFADERWRNYHNRMSELGFD--ID
MLBr_02640|M.leprae_Br4923 GLFTEIGGLSAVGSRIAVETSPLHGDEWREQMQLRFRRVSDALGFEQAVD
** : **: * :. * * : ::
MAV_4435|M.avium_104 LSGLFFDGE-RSNVVEYLTGRGWRVSARPRRDLFDDYGLAYPEDDET---
MMAR_1068|M.marinum_M LSGLFYEGE-RSNVVDYLTEHGWHVAARPRQDLFTDYGRVFP-DADT---
MSMEG_1481|M.smegmatis_MC2_155 LSDLWYGGD-RNAADEYLAGHGWQVSTRPRPEVFAAYGRTFPDLTLTGDD
TH_2706|M.thermoresistible__bu LSELFHPGE-RTPVVDYLRGRGWDARARPRAEVFAGYGREFPDSAAL---
MUL_0817|M.ulcerans_Agy99 MAELIYHGD-RNTVIDYLADHGWRVRARTFEEMHAHNGFEPPDDEMM---
Mflv_5025|M.gilvum_PYR-GCK MPSLVYTGA-RTPVMDHLRGAGWQVSGTARAELFARFGRPLPQDADGT--
Mvan_1344|M.vanbaalenii_PYR-1 MPSLVYAGT-RSHVMDYLAGQGWEVTGVPRRELFTRYGRPLPPEAGDT--
MAB_3787|M.abscessus_ATCC_1997 LESLVYTQE-RQMAADWLAEHGWTVITEENDELYARLN-LDPPNPLLR--
Mb0853|M.bovis_AF2122/97 LNELVYHGQ-RGHVLDYLTRDGWQTSALTVTQLYEANGFAYPDDELAT--
Rv0830|M.tuberculosis_H37Rv LNELVYHGQ-RGHVLDYLTRDGWQTSALTVTQLYEANGFAYPDDELAT--
MLBr_02640|M.leprae_Br4923 VQELIYHDENRAVVADWLNRHGWRATAQSAPDEMRRVGRWGDGVPMAD--
: * . * . : * ** . : .
MAV_4435|M.avium_104 -AQFPNIVAVSAELG-------
MMAR_1068|M.marinum_M -SQLRSIVAVTATFGEAG----
MSMEG_1481|M.smegmatis_MC2_155 NAAMRQSVAITATRS-------
TH_2706|M.thermoresistible__bu -AAMRDSSAVTAVRPVVRAGMR
MUL_0817|M.ulcerans_Agy99 -ALFGGMSYVTGIRK-------
Mflv_5025|M.gilvum_PYR-GCK -DPLGEIVYVSATLAADA----
Mvan_1344|M.vanbaalenii_PYR-1 -DPLGEIVYVSAHRPQ------
MAB_3787|M.abscessus_ATCC_1997 -SIFPNIVYVDATLG-------
Mb0853|M.bovis_AF2122/97 --AFADLTYSSATLMR------
Rv0830|M.tuberculosis_H37Rv --AFADLTYSSATLMR------
MLBr_02640|M.leprae_Br4923 -DKDAFAEFVTAHRL-------
.