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ARTDTDSWDLASSVGATATMVAAARAIASTEPNALIDDPYAADLVRKVGLEFFTKLVDGDIALDGDDAAA AGLMVSMMAVRTRFFDDFFCDAAGAGIRQSVILAAGLDSRAYRLGWPAGTVVYEIDQPRVIEAKTAAMAE IGASPTAERRTVAVDLRDDWPAALRAAGFDAATPTAWIAEGLLVYLPPEAQDRLFDNITALSARGSRLAT EYHPDITSTLRGRGQAMSERWRDHGFDVDLSDLWYGGDRNAADEYLAGHGWQVSTRPRPEVFAAYGRTFP DLTLTGDDNAAMRQSVAITATRS*
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. smegmatis MC2 155 | MSMEG_1481 | - | - | 100% (304) | methyltransferase |
| M. smegmatis MC2 155 | MSMEG_1480 | - | 3e-94 | 60.34% (290) | methyltransferase |
| M. smegmatis MC2 155 | MSMEG_1482 | - | 6e-92 | 59.03% (310) | methyltransferase |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb3432 | - | 1e-87 | 58.80% (284) | hypothetical protein Mb3432 |
| M. gilvum PYR-GCK | Mflv_5025 | - | 1e-93 | 58.03% (305) | putative methyltransferase |
| M. tuberculosis H37Rv | Rv3399 | - | 1e-87 | 58.80% (284) | hypothetical protein Rv3399 |
| M. leprae Br4923 | MLBr_02640 | - | 1e-65 | 47.49% (299) | hypothetical protein MLBr_02640 |
| M. abscessus ATCC 19977 | MAB_3787 | - | 1e-83 | 57.30% (281) | hypothetical protein MAB_3787 |
| M. marinum M | MMAR_1068 | - | 1e-105 | 63.25% (302) | O-methyltransferase |
| M. avium 104 | MAV_4435 | - | 1e-99 | 60.86% (304) | methyltransferase, putative, family protein |
| M. thermoresistible (build 8) | TH_2706 | - | 1e-106 | 63.73% (306) | PUTATIVE putative methyltransferase |
| M. ulcerans Agy99 | MUL_0816 | - | 6e-91 | 58.80% (284) | O-methyltransferase |
| M. vanbaalenii PYR-1 | Mvan_1344 | - | 7e-93 | 61.40% (285) | putative methyltransferase |
CLUSTAL 2.0.9 multiple sequence alignment
MSMEG_1481|M.smegmatis_MC2_155 ------------------------------------------MARTDTDS
TH_2706|M.thermoresistible__bu ------------------------------------------MARSESDT
MMAR_1068|M.marinum_M ------------------------------------------MTRTDQDS
MAV_4435|M.avium_104 ------------------------------------------MTRTDQDS
Mb3432|M.bovis_AF2122/97 MARPMGKLPSNTRKCAQCAMAEALLEIAGQTINQKDLGRSGRMTRTDNDT
Rv3399|M.tuberculosis_H37Rv MARPMGKLPSNTRKCAQCAMAEALLEIAGQTINQKDLGRSGRMTRTDNDT
MAB_3787|M.abscessus_ATCC_1997 ------------------------------------------MARTDDDS
Mflv_5025|M.gilvum_PYR-GCK ------------------------------------------MARTPDDS
Mvan_1344|M.vanbaalenii_PYR-1 ------------------------------------------MARTADDS
MUL_0816|M.ulcerans_Agy99 ------------------------------------------MARTHDDK
MLBr_02640|M.leprae_Br4923 -------------------------------------------MRTHDDT
*: *.
MSMEG_1481|M.smegmatis_MC2_155 WDLASSVGATATMVAAARAIASTEPNALIDDPYAADLVRKVGL-EFFTKL
TH_2706|M.thermoresistible__bu WDLTSGVGVTATMVAAARALASREPEPLIDDPFAAPLVRAVGV-EFFTRL
MMAR_1068|M.marinum_M WDLASSVGATATMVAAARALASAEANPIIDDPFAAPLVRAVGL-DFFTRL
MAV_4435|M.avium_104 WDLASSVGATATMVAAARALASTGERPIINDPFAAPLVRAVGL-DFFRRL
Mb3432|M.bovis_AF2122/97 WDLASSVGATATMIATARALASRAENPLINDPFAEPLVRAVGI-DLFTRL
Rv3399|M.tuberculosis_H37Rv WDLASSVGATATMIATARALASRAENPLINDPFAEPLVRAVGI-DLFTRL
MAB_3787|M.abscessus_ATCC_1997 WDLASSVGATATMVAAQRALASHVPNPLINDPYAEPLVRAVGI-EYFTKL
Mflv_5025|M.gilvum_PYR-GCK WDLASSVGATATMVAAGRAVASADPDPLINDPYAEPLVRAVGL-DFFTRM
Mvan_1344|M.vanbaalenii_PYR-1 WDPASSVGATATMVAAGRAAASADPDPLINDPYAEPLVRAVGL-SFFTKM
MUL_0816|M.ulcerans_Agy99 WDLASSVGATATIVAAGRAMASRDPRGLIDDPFAEPLVRAVGV-DFFIKM
MLBr_02640|M.leprae_Br4923 WDIKTSVGTTAVMVAAARAAETDRPDALIRDPYAKLLVTNTGAGALWEAM
** :.**.**.::*: ** : :* **:* ** .* : :
MSMEG_1481|M.smegmatis_MC2_155 VDGDIALDGD-----DAAAAGLMVSMMAVRTRFFDDFFCDAAGAGIRQSV
TH_2706|M.thermoresistible__bu VDGDLELPADTA--EERAAAQVLTEVMAVRTRFFDDFFTDATRVGARQAV
MMAR_1068|M.marinum_M AEGEID--HDEQ--AQRDR-QLVADSIAVRTRFFDDFFLDAARRGVRQSV
MAV_4435|M.avium_104 VDGEVAPADPQR--GERDL-QLETDSIAVRTRFFDDFFTGAARDGIRQSV
Mb3432|M.bovis_AF2122/97 ASGELRLEDIG---DHATGGRWMIDNIAIRTKFYDDFFGDATTAGIRQVV
Rv3399|M.tuberculosis_H37Rv ASGELRLEDIG---DHATGGRWMIDNIAIRTKFYDDFFGDATTAGIRQVV
MAB_3787|M.abscessus_ATCC_1997 ASGAFDPEQMAGLVQLGITADGMANGMASRTWYYDTAFESSTAAGVRQAV
Mflv_5025|M.gilvum_PYR-GCK LDGELDLSVFPD--SSPERAQAMIDGMAVRTRFFDDCCLAAASAGVRQVV
Mvan_1344|M.vanbaalenii_PYR-1 LDGELDLSQFAD--GSPERVQAMIDGMAVRTRFFDDCCGTSTTAGITQVV
MUL_0816|M.ulcerans_Agy99 MDGEFDLSVLQN--VSSAKAQAMVDGMAVRTKYFDDYFGDAIKSGIRQAV
MLBr_02640|M.leprae_Br4923 LDPSMVAKVEAIDAEAAAMVEHMRSYQAVRTNFFDTYFNNAVIDGIRQFV
. . . * ** ::* : * * *
MSMEG_1481|M.smegmatis_MC2_155 ILAAGLDSRAYRLGWPAGTVVYEIDQPRVIEAKTAAMAEIGASPTAERRT
TH_2706|M.thermoresistible__bu ILASGLDARAYRLTWPDGTVVYEIDQPEVIAFKTRTLAELGAPPTAPHRP
MMAR_1068|M.marinum_M ILAAGLDARAYRLPWPSGSVVYEVDQPDVIDFKDTTMSALGAVPTATRRT
MAV_4435|M.avium_104 ILAAGLDARAYRLDWPAGAVVYEVDQPKVVEFKTNTMAALDARPAAQLRT
Mb3432|M.bovis_AF2122/97 ILAAGLDTRAYRLPWPPGTVVYEIDQPAVIKFKTRALANLNAEPNAERHA
Rv3399|M.tuberculosis_H37Rv ILAAGLDTRAYRLPWPPGTVVYEIDQPAVIKFKTRALANLNAEPNAERHA
MAB_3787|M.abscessus_ATCC_1997 ILASGLDTRAYRLTWPAGTTVYELDQPEVITFKTDTLAELGASPSAERRT
Mflv_5025|M.gilvum_PYR-GCK ILAAGLDARTYRLPWPDGTVVYELDQPDVIAFKTQTLRNLGAEPAATQRP
Mvan_1344|M.vanbaalenii_PYR-1 ILASGLDARAYRLGWPAGTVVYELDQPAVIEFKTRTLAGLGAHPTATHRP
MUL_0816|M.ulcerans_Agy99 ILASGLDARAYRLPWPADTVVYELDQPQVIEFKTNVLADLGAEPRATRRA
MLBr_02640|M.leprae_Br4923 ILASGLDSRAYRLDWPTGTTVYEIDQPKVLAYKSTTLAEHGVTPTADRRE
***:***:*:*** ** .:.***:*** *: * .: .. * * :
MSMEG_1481|M.smegmatis_MC2_155 VAVDLRDDWPAALRAAGFDAATPTAWIAEGLLVYLPPEAQDRLFDNITAL
TH_2706|M.thermoresistible__bu VAVDLRDDWPAALTAAGFDPTVATAWSAEGLLRYLPPDAQDRLFDHITDL
MMAR_1068|M.marinum_M VRVDLRDDWPAALRHNGFDTTQPTAWSAEGLLMYLPPDAQDRLFDAISGL
MAV_4435|M.avium_104 VSIDLREDWPEALRANGFDVTQATSWSAEGLLMYLPPEAQDRLFDNITAL
Mb3432|M.bovis_AF2122/97 VAVDLRNDWPTALKNAGFDPARPTAFSAEGLLSYLPPQGQDRLLDAITAL
Rv3399|M.tuberculosis_H37Rv VAVDLRNDWPTALKNAGFDPARPTAFSAEGLLSYLPPQGQDRLLDAITAL
MAB_3787|M.abscessus_ATCC_1997 VAIDLREDWPAALQAAGFDPEQPTVWSAEGLLIYLPPEAQDRLFASITEL
Mflv_5025|M.gilvum_PYR-GCK VPVDLREDWPAALRAAGFDATRPTAWLAEGLLIYLPPEAQDALFDTVTAL
Mvan_1344|M.vanbaalenii_PYR-1 VPIDLREDWPAALHAAGFDASRPTAWLAEGLLIYLPPEAQDQLFDRITAL
MUL_0816|M.ulcerans_Agy99 IPIDLRGDWPVALRAAGLDTTAPTAWLAEGLLIYLPPEAQDRLFDNITAL
MLBr_02640|M.leprae_Br4923 VPIDLRQDWPPALRSAGFDPSARTAWLAEGLLMYLPATAQDGLFTEIGGL
: :*** *** ** *:* * : ***** ***. .** *: : *
MSMEG_1481|M.smegmatis_MC2_155 SARGSRLATEYHPDI-TSTLRG---RGQAMSERWRDHGFDVDLSDLWYGG
TH_2706|M.thermoresistible__bu SAPGSRLATEDHPGP-GAGLGE---KADELGRRWREHGFEVQLSELFHPG
MMAR_1068|M.marinum_M SAPGSRLATEYHPDP-GSTMAE---RAQQFNQRWVRLGCDIDLSGLFYEG
MAV_4435|M.avium_104 SAPGSRLATEYHPDATGTTMAQ---RAQEFNDRWARVGCDIDLSGLFFDG
Mb3432|M.bovis_AF2122/97 SAPDSRLATQSPLVLDLAEEDEKKMRMKSAAEAWRERGFDLDLTELIYFD
Rv3399|M.tuberculosis_H37Rv SAPDSRLATQSPLVLDLAEEDEKKMRMKSAAEAWRERGFDLDLTELIYFD
MAB_3787|M.abscessus_ATCC_1997 SAPGSRLVCEQVPGLETADFS----KARELTRQFAGETLDLDLESLVYTQ
Mflv_5025|M.gilvum_PYR-GCK SAPGSTLATEYVPGIVDFDGA----KARALSEPLREHGLDIDMPSLVYTG
Mvan_1344|M.vanbaalenii_PYR-1 SAPGSTIATEYAPGIIDFDDE----KARAMSAPMREMGLDIDMPSLVYAG
MUL_0816|M.ulcerans_Agy99 SAPGSTVATEFVPGIVDFDVD----RARQMSGPFRDHGLDIDMSSLVYTG
MLBr_02640|M.leprae_Br4923 SAVGSRIAVETSPLHGDEWREQMQLRFRRVSDALG-FEQAVDVQELIYHD
** .* :. : : ::: * .
MSMEG_1481|M.smegmatis_MC2_155 D-RNAADEYLAGHGWQVSTRPRPEVFAAYGRTFPDLTLTGDDNAAMRQSV
TH_2706|M.thermoresistible__bu E-RTPVVDYLRGRGWDARARPRAEVFAGYGREFPDSAAL----AAMRDSS
MMAR_1068|M.marinum_M E-RSNVVDYLTEHGWHVAARPRQDLFTDYGRVFP-DADT----SQLRSIV
MAV_4435|M.avium_104 E-RSNVVEYLTGRGWRVSARPRRDLFDDYGLAYPEDDET----AQFPNIV
Mb3432|M.bovis_AF2122/97 Q-RNDVADYLAGSGWQVTTSTGKELFAAQGLP-PFEDDHI---TRFADRR
Rv3399|M.tuberculosis_H37Rv Q-RNDVADYLAGSGWQVTTSTGKELFAAQGLP-PFADDHI---TRFADRR
MAB_3787|M.abscessus_ATCC_1997 E-RQMAADWLAEHGWTVITEENDELYARLNLD-PPNPLLR---SIFPNIV
Mflv_5025|M.gilvum_PYR-GCK A-RTPVMDHLRGAGWQVSGTARAELFARFGRPLPQDADGT---DPLGEIV
Mvan_1344|M.vanbaalenii_PYR-1 T-RSHVMDYLAGQGWEVTGVPRRELFTRYGRPLPPEAGDT---DPLGEIV
MUL_0816|M.ulcerans_Agy99 A-RNHVVDYLRAKGWDAEGVTRSKLFERNGMAVPAPSDD----DPLGEII
MLBr_02640|M.leprae_Br4923 ENRAVVADWLNRHGWRATAQSAPDEMRRVGRWGDGVPMAD---DKDAFAE
* . : * ** . . .
MSMEG_1481|M.smegmatis_MC2_155 AITATRS-------
TH_2706|M.thermoresistible__bu AVTAVRPVVRAGMR
MMAR_1068|M.marinum_M AVTATFGEAG----
MAV_4435|M.avium_104 AVSAELG-------
Mb3432|M.bovis_AF2122/97 YISAVLK-------
Rv3399|M.tuberculosis_H37Rv YISAVLK-------
MAB_3787|M.abscessus_ATCC_1997 YVDATLG-------
Mflv_5025|M.gilvum_PYR-GCK YVSATLAADA----
Mvan_1344|M.vanbaalenii_PYR-1 YVSAHRPQ------
MUL_0816|M.ulcerans_Agy99 FISAALTG------
MLBr_02640|M.leprae_Br4923 FVTAHRL-------
: *