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M. avium 104 MAV_4550 (-)

annotation: virulence factor Mce family protein
coordinates: 4682447 - 4683478
length: 343

RITGTAVKLVVFWSVLAMFTVMIIVVFGQVRFDRTTGYSAVFTDAGGLRAGQFVRASGVEVGKVAAVTLS
GKDSRVLVEFNVDRSLALDQGTTASIRYLNLIGDRYLELKRGTSGRRLPPGGRIPVEHTQPALDLDALIG
GFRPLFQALDPNKVNSIAQSIITVFQGQGATITDILDQTAALTAALADRDKAIGEVINNLNTVLATTVKH
EKEFDRTVDKLELLITGLKNRADPLAAAAAHISDAAATVAGLLGEDRPSLHGTLGHLEGIQQALINDLPT
ADNVLEKLPGAFRVIGRAGGIYGDFYNFYLCDISIKVNGLQPGGPVRTIKLFGQPTGRCTPQ*

Operon Prediction Model: Genebank

Paralogs

species id gene e-value identity (len) annotation
M. avium 104 MAV_4550 - - 100% (343) virulence factor Mce family protein
M. avium 104 MAV_5014 - e-126 65.90% (346) virulence factor Mce family protein
M. avium 104 MAV_2062 - 1e-86 46.65% (343) virulence factor Mce family protein

Closest Orthologs (e-value cutoff: 1e-4)

species id gene e-value identity (len) annotation
M. bovis AF2122 / 97 Mb0605 mce2B 1e-156 79.88% (343) MCE-family protein MCE2B
M. gilvum PYR-GCK Mflv_0710 - 1e-134 68.22% (343) virulence factor Mce family protein
M. tuberculosis H37Rv Rv0170 mce1B 1e-120 63.01% (346) MCE-family protein MCE1B
M. leprae Br4923 MLBr_02590 mce1B 1e-123 63.58% (346) putative secreted protein
M. abscessus ATCC 19977 MAB_4152c - 6e-64 40.71% (339) MCE-family protein
M. marinum M MMAR_0413 mce1B 1e-124 63.87% (346) MCE-family protein Mce1B
M. smegmatis MC2 155 MSMEG_0135 - 1e-122 62.68% (343) virulence factor Mce family protein
M. thermoresistible (build 8) TH_3551 - 1e-135 69.10% (343) PUTATIVE virulence factor Mce family protein
M. ulcerans Agy99 MUL_1063 mce1B 1e-124 63.87% (346) MCE-family protein Mce1B
M. vanbaalenii PYR-1 Mvan_0135 - 1e-132 67.93% (343) virulence factor Mce family protein

CLUSTAL 2.0.9 multiple sequence alignment


MAV_4550|M.avium_104                MRITGTAVKLVVFWSVLAMFTVMIIVVFGQVRFDRTTGYSAVFTDAGGLR
Mb0605|M.bovis_AF2122/97            MKTTGTTIKLGIVWLVLSVFTVMIIVVFGQVRFHHTTGYSAVFTHVSGLR
Mflv_0710|M.gilvum_PYR-GCK          MKITGTAIKLGAFALVLLMFTAIIIVVFGQMRFDRTTGYSAIFSNASGLR
Mvan_0135|M.vanbaalenii_PYR-1       MKITGTAIKLGAFSLVLLMFTAIIIVVFGQMRFDRTTGYSAIFSSASGLR
MSMEG_0135|M.smegmatis_MC2_155      MSIKGTLFKLGIFSLVLLTFTALIFVVFGQIRFNRTTEYSAIFKNVSGLR
TH_3551|M.thermoresistible__bu      MKITGTAIKLGAFSVVLLVFTALIVVVFGQVRFDRTTGYTAVFSSASGLR
MMAR_0413|M.marinum_M               MKITGTAIRLGIFSLVLMLFSVMIIIVFGQIRFDRTYAYSAEFSNASGLR
MUL_1063|M.ulcerans_Agy99           MKITGTAIRLGIFSLVLMLFSVMIIIVFGQIRFDRTYAYSAEFSNASGLR
MLBr_02590|M.leprae_Br4923          MKLTGTVVRLSIFSLVLLLFTVMIIVVFGQMRFGRTNGYTAEFTNISGLR
Rv0170|M.tuberculosis_H37Rv         MKITGTVVKLGIVSVVLLFFTVMIIVIFGQMRFDRTNGYTAEFSNVSGLR
MAB_4152c|M.abscessus_ATCC_199      MKR-ATQIKVIVFTVVMLLVAAGLIITFGEFRFGSGKRYHAMFSTASDLR
                                    *   .* .::  .  *:  .:. :.: **:.**     * * *.  ..**

MAV_4550|M.avium_104                AGQFVRASGVEVGKVAAVTLSGKDSRVLVEFNVDRSLALDQGTTASIRYL
Mb0605|M.bovis_AF2122/97            AGQFVRAAGVEVGKVAKVTLIDGDKQVLVDFTVDRSLSLDQATTASIRYL
Mflv_0710|M.gilvum_PYR-GCK          SGQFVRASGVEVGKVKGVELIDNGSKVRVDFDVDRSLELFDETTASVRYL
Mvan_0135|M.vanbaalenii_PYR-1       PGQFVRASGVEVGKVKGVELIEGGSKVRVDFNVDRSLELFDESTASIRYL
MSMEG_0135|M.smegmatis_MC2_155      DGQFVRAAGVEVGKVKSVDLINGGEQAEVKFTVERSLPLFQETTAAIRYQ
TH_3551|M.thermoresistible__bu      AGQFVRAAGVEVGKVSKVELIDGGQRVRVDFNVDRSLPLFQDTTATIRYL
MMAR_0413|M.marinum_M               PGQFVRASGVEIGKVKSVSLIDGGKRVRVNFDVDRSVPLYQSTSAQIRYL
MUL_1063|M.ulcerans_Agy99           PGQFVRASGVEIGKVKSVSLIDGGKRVRVNFDVDRSVPLYQSTSAQIRYL
MLBr_02590|M.leprae_Br4923          TGQFVRASGVEVGKVNSVALINGGTRVRVKFNVDRSVPLYQSTTAQIRYL
Rv0170|M.tuberculosis_H37Rv         QGQFVRASGVEIGKVKALHLVDGGRRVRVEFNIDRSVPLYQSTTAQIRYS
MAB_4152c|M.abscessus_ATCC_199      SGQKVRIAGVPVGRVKNVSL-NRDNSVEVTFDVDSKYQLYSSSRAIIRYE
                                     ** ** :** :*:*  : *   .  . * * :: .  * . : * :** 

MAV_4550|M.avium_104                NLIGDRYLELKRGT---SGRRLPPGGRIPVEHTQPALDLDALIGGFRPLF
Mb0605|M.bovis_AF2122/97            NLIGDRYLELGRGH---SGQRLAPGATIPLEHTHPALDLDALLGGFRPLF
Mflv_0710|M.gilvum_PYR-GCK          NLIGDRYLELARGD---SNTRLAAGGTIPVERTQPALDLDALIGGFRPVF
Mvan_0135|M.vanbaalenii_PYR-1       NLIGDRYLELARGE---SNTRMAAGGTIPIERTQPALDLDALIGGFRPVF
MSMEG_0135|M.smegmatis_MC2_155      DLIGNRYLELKRGD---SDQILPPGSTIPVERTEPALDLDALVGGFRPLF
TH_3551|M.thermoresistible__bu      NLIGDRYLELKRGN---SNERLPAGGEIPLERTQPALDLDALVGGFRPLF
MMAR_0413|M.marinum_M               DLIGNRYLELKRGEGDGSDRIMPPGGFIPLSRTSPALDLDALIGGFKPVF
MUL_1063|M.ulcerans_Agy99           DLIGNRYLELKRGEGDGSDRIMPPGGFIPLSRTSPALDLDALIGGFKPVF
MLBr_02590|M.leprae_Br4923          DLIGNRYLELKHGEGQGSEKIMPAGGLIPLSRTSPALDLDALIGGFKPLF
Rv0170|M.tuberculosis_H37Rv         DLIGNRYVELKRGEGKGANDLLPPGGLIPLSRTSPALDLDALIGGFKPVF
MAB_4152c|M.abscessus_ATCC_199      NLVGDRYLEITAGPG--ELHKLPDGGTLDKEHTQPALDLDALLGGLRPVL
                                    :*:*:**:*:  *        :. *. :  .:* ********:**::*::

MAV_4550|M.avium_104                QALDPNKVNSIAQSIITVFQGQGATITDILDQTAALTAALADRDKAIGEV
Mb0605|M.bovis_AF2122/97            QTLDPDKVNSIASSIITVFQGQGATINDILDQTASLTATLADRDHAIGEV
Mflv_0710|M.gilvum_PYR-GCK          QSLDPEKVNTIAQSLITVFQGQGGTINDILDQTASLTSALADRDQAIGEV
Mvan_0135|M.vanbaalenii_PYR-1       QSLEPEKVNTIAQSIITVFQGQGGTINDILDQTASLTSALADRDQAIGEV
MSMEG_0135|M.smegmatis_MC2_155      RSLEPEKVNTIATSLITIFQGQGGTINDILDQTAQLTASLADRDQAIGEV
TH_3551|M.thermoresistible__bu      RALDAEKVNTIAQSIITVFQGQGGTINDILDQTAQLTATLADRDQAIGEV
MMAR_0413|M.marinum_M               RALDPDKVNTIASALVTVFQGQGGTINDILDQTAQLTSQLAERDQAIGEV
MUL_1063|M.ulcerans_Agy99           RALDPDKVNTIASALVTVFQGQGGTINDILDQTAWLTSQLAERDQAIGEV
MLBr_02590|M.leprae_Br4923          RALDPDKINTIASAIVAAFQGQGGTINDILDQTAQLTTAIGERDQAIGEV
Rv0170|M.tuberculosis_H37Rv         RALDPAKVNNIANALITVFQGQGGTINDILDQTAQLTSQIAERDQAIGEV
MAB_4152c|M.abscessus_ATCC_199      KGFDAAKVNEISNAFIQILQGQGGTLSQLLGDTSSFTSGLAERDQLIGDV
                                    : ::. *:* *: :::  :****.*:.::*.:*: :*: :.:**: **:*

MAV_4550|M.avium_104                INNLNTVLATTVKHEKEFDRTVDKLELLITGLKNRADPLAAAAAHISDAA
Mb0605|M.bovis_AF2122/97            VNNLNTVLATTVKHQTEFDRTVDKLEVLITGLKNRADPLAAAAAHISSAA
Mflv_0710|M.gilvum_PYR-GCK          VTNLNTVLDTTVRHQQEFDDTVKNFEVLITGLKNRADPLAESVADISDAA
Mvan_0135|M.vanbaalenii_PYR-1       ITNLNTVLDTTVRHQQEFDDTVKNFEVLITGLKNRADPIATSVADISDAA
MSMEG_0135|M.smegmatis_MC2_155      IKNLNTVLDTTVRHQKQFDETLVNFETLITGLKNRADPIATSVADISDAA
TH_3551|M.thermoresistible__bu      IRNLNTVLETTVRHQKEFDETIHNFEVLITGLRNRADPIAESTANISNAA
MMAR_0413|M.marinum_M               IKNLNTVLDATVRHRKDFDQTVNNLEVLITGLNEHRDDLSGGIAHVSNAA
MUL_1063|M.ulcerans_Agy99           IKNLNTVLDATVRHRKDFDQTVNNLEVLITGLNEHRDDLSGGIAHVSNAA
MLBr_02590|M.leprae_Br4923          VKNLNVVLDTTVRHRKEFDQTVNNLEILITGLKDHGDQLAGSFAHISNAA
Rv0170|M.tuberculosis_H37Rv         VKNLNIVLDTTVKHRKEFDETVNNLENLITGLRNHSDQLAGGLAHISNGA
MAB_4152c|M.abscessus_ATCC_199      INHLNEVLATVDSKSTQFSSSVDQLQQLISGLAQQRDVVAGALPPLASTA
                                    : :** ** :.  :  :*. :: ::: **:** :: * :: . . ::. *

MAV_4550|M.avium_104                ATVAGLLGEDRPSLHGTLGHLEGIQQALINDLPTADNVLEKLPGAFRVIG
Mb0605|M.bovis_AF2122/97            GTLADLLGADRPLLHSSFGHLEGIQQPLIDELAELDHVLGKLPDAYRIIG
Mflv_0710|M.gilvum_PYR-GCK          GTIGDLLADNRPLLQSTISKLEILNQPLVDQKDQLNQLLEQIPDALAIIG
Mvan_0135|M.vanbaalenii_PYR-1       GTIGDLLADNRPLLKDTVSKLEILNQPLVDQRDQLNDLLVKLPDALAIIG
MSMEG_0135|M.smegmatis_MC2_155      GSLADLLSDNRPLLKDTIGYLDVIQAPLVEQKQEVSDILVQMPQALKIIG
TH_3551|M.thermoresistible__bu      GTLADVLAQNRPLLDNSIDHLEAVQGPLVEQSAELNNILVQLPTALKTIG
MMAR_0413|M.marinum_M               GTVADLLGEDRALLHKTVNYLDAVQQPLIDQRQELADFLHKVPTALNMIG
MUL_1063|M.ulcerans_Agy99           GTVADLLGEDRALLHKTVNYLDAVQQPLIDQRQELADFLHKVPTALNMIG
MLBr_02590|M.leprae_Br4923          GTVANLLAEDHALLHKSINYLDGIQQPLIDQRLQLEDYLHKLPTVLNQIG
Rv0170|M.tuberculosis_H37Rv         GTVADLLAENRTLVRKAVSYLDAIQQPVIDQRVELDDLLHKTPTALTALG
MAB_4152c|M.abscessus_ATCC_199      SSLESVLKDTRPYIKGTIEQARQLATRVDERKADVNVVVENLAENYLRLN
                                    .:: .:*   :. :  :.     :   : :        : : .     :.

MAV_4550|M.avium_104                RAGGIYGDFYNFYLCDISIKVNGLQPGGPVRTIKLFGQPT-GRCTPQ--
Mb0605|M.bovis_AF2122/97            RAGGIYGDFFNFYLCDISLKVNGLQPGGPVRTVKLFGQPT-GRCTPQ--
Mflv_0710|M.gilvum_PYR-GCK          RSGGIYGDFFNFYACDVTLKLNGLQPGGPVRTVRVWSQPT-GRCTPQ--
Mvan_0135|M.vanbaalenii_PYR-1       RSGGVYGDFFNFYACDVTLKLNGLQPGGPVRTVKVWSQPS-GRCTPQ--
MSMEG_0135|M.smegmatis_MC2_155      RAGGIYGDFFNFYACDLTLKLNGLQPGGPVRTVRITTQPS-GRCTPK--
TH_3551|M.thermoresistible__bu      RAGGVYGDFFNFYACDISLKLNGLQPGGPVRTVKITTQPS-GRCTPQ--
MMAR_0413|M.marinum_M               RAIGSYGDFVNFYSCDISLKINGLQPGGPVRTVRLFSQPT-GRCAPQ--
MUL_1063|M.ulcerans_Agy99           RAIGSYGDFVNFYSCDISLKINGLQPGGPVRTVRLFSQPT-GRCAPQ--
MLBr_02590|M.leprae_Br4923          RTIGSYGDFVNFYSCDITLKINGLQPGGPVRTVRLFQQPT-GRCTPQ--
Rv0170|M.tuberculosis_H37Rv         RANGTYGDFQNFYLCDLQIKWNGFQAGGPVRTVKLFSQPT-GRCTPQ--
MAB_4152c|M.abscessus_ATCC_199      -ALGAYGSFFNIYYCSIRIKVNGPVGTDWLIPFGGPPDPSKGRCAFKNE
                                     : * **.* *:* *.: :* **    . : ..    :*: ***: :

species	id	gene	e-value	identity (len)	annotation
M. avium 104	MAV_4550	-	-	100% (343)	virulence factor Mce family protein
M. avium 104	MAV_5014	-	e-126	65.90% (346)	virulence factor Mce family protein
M. avium 104	MAV_2062	-	1e-86	46.65% (343)	virulence factor Mce family protein