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MKITGTAIKLGAFSLVLLMFTAIIIVVFGQMRFDRTTGYSAIFSSASGLRPGQFVRASGVEVGKVKGVEL IEGGSKVRVDFNVDRSLELFDESTASIRYLNLIGDRYLELARGESNTRMAAGGTIPIERTQPALDLDALI GGFRPVFQSLEPEKVNTIAQSIITVFQGQGGTINDILDQTASLTSALADRDQAIGEVITNLNTVLDTTVR HQQEFDDTVKNFEVLITGLKNRADPIATSVADISDAAGTIGDLLADNRPLLKDTVSKLEILNQPLVDQRD QLNDLLVKLPDALAIIGRSGGVYGDFFNFYACDVTLKLNGLQPGGPVRTVKVWSQPSGRCTPQ
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. vanbaalenii PYR-1 | Mvan_0135 | - | - | 100% (343) | virulence factor Mce family protein |
| M. vanbaalenii PYR-1 | Mvan_4398 | - | 2e-83 | 48.25% (342) | virulence factor Mce family protein |
| M. vanbaalenii PYR-1 | Mvan_4603 | - | 7e-76 | 46.22% (344) | virulence factor Mce family protein |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb0605 | mce2B | 1e-136 | 69.97% (343) | MCE-family protein MCE2B |
| M. gilvum PYR-GCK | Mflv_0710 | - | 0.0 | 92.13% (343) | virulence factor Mce family protein |
| M. tuberculosis H37Rv | Rv0170 | mce1B | 1e-130 | 64.74% (346) | MCE-family protein MCE1B |
| M. leprae Br4923 | MLBr_02590 | mce1B | 1e-130 | 65.61% (346) | putative secreted protein |
| M. abscessus ATCC 19977 | MAB_4152c | - | 1e-64 | 41.46% (316) | MCE-family protein |
| M. marinum M | MMAR_0413 | mce1B | 1e-133 | 67.05% (346) | MCE-family protein Mce1B |
| M. avium 104 | MAV_5014 | - | 1e-134 | 67.34% (346) | virulence factor Mce family protein |
| M. smegmatis MC2 155 | MSMEG_0135 | - | 1e-148 | 73.47% (343) | virulence factor Mce family protein |
| M. thermoresistible (build 8) | TH_3551 | - | 1e-155 | 77.84% (343) | PUTATIVE virulence factor Mce family protein |
| M. ulcerans Agy99 | MUL_1063 | mce1B | 1e-133 | 67.05% (346) | MCE-family protein Mce1B |
CLUSTAL 2.0.9 multiple sequence alignment
MLBr_02590|M.leprae_Br4923 MKLTGTVVRLSIFSLVLLLFTVMIIVVFGQMRFGRTNGYTAEFTNISGLR
MAV_5014|M.avium_104 MKITGTLVRLSIFSVVLLIFTVMIIVVFGQMRFDRTNGYSAEFSNISGLR
MMAR_0413|M.marinum_M MKITGTAIRLGIFSLVLMLFSVMIIIVFGQIRFDRTYAYSAEFSNASGLR
MUL_1063|M.ulcerans_Agy99 MKITGTAIRLGIFSLVLMLFSVMIIIVFGQIRFDRTYAYSAEFSNASGLR
Rv0170|M.tuberculosis_H37Rv MKITGTVVKLGIVSVVLLFFTVMIIVIFGQMRFDRTNGYTAEFSNVSGLR
Mvan_0135|M.vanbaalenii_PYR-1 MKITGTAIKLGAFSLVLLMFTAIIIVVFGQMRFDRTTGYSAIFSSASGLR
Mflv_0710|M.gilvum_PYR-GCK MKITGTAIKLGAFALVLLMFTAIIIVVFGQMRFDRTTGYSAIFSNASGLR
MSMEG_0135|M.smegmatis_MC2_155 MSIKGTLFKLGIFSLVLLTFTALIFVVFGQIRFNRTTEYSAIFKNVSGLR
TH_3551|M.thermoresistible__bu MKITGTAIKLGAFSVVLLVFTALIVVVFGQVRFDRTTGYTAVFSSASGLR
Mb0605|M.bovis_AF2122/97 MKTTGTTIKLGIVWLVLSVFTVMIIVVFGQVRFHHTTGYSAVFTHVSGLR
MAB_4152c|M.abscessus_ATCC_199 MKR-ATQIKVIVFTVVMLLVAAGLIITFGEFRFGSGKRYHAMFSTASDLR
*. .* .:: . :*: .:. :.: **:.** * * *. *.**
MLBr_02590|M.leprae_Br4923 TGQFVRASGVEVGKVNSVALINGGTRVRVKFNVDRSVPLYQSTTAQIRYL
MAV_5014|M.avium_104 AGQFVRASGVEVGKVSSVQLVDGGKRARVEFNVDRSVPLYQSTTAQIRYL
MMAR_0413|M.marinum_M PGQFVRASGVEIGKVKSVSLIDGGKRVRVNFDVDRSVPLYQSTSAQIRYL
MUL_1063|M.ulcerans_Agy99 PGQFVRASGVEIGKVKSVSLIDGGKRVRVNFDVDRSVPLYQSTSAQIRYL
Rv0170|M.tuberculosis_H37Rv QGQFVRASGVEIGKVKALHLVDGGRRVRVEFNIDRSVPLYQSTTAQIRYS
Mvan_0135|M.vanbaalenii_PYR-1 PGQFVRASGVEVGKVKGVELIEGGSKVRVDFNVDRSLELFDESTASIRYL
Mflv_0710|M.gilvum_PYR-GCK SGQFVRASGVEVGKVKGVELIDNGSKVRVDFDVDRSLELFDETTASVRYL
MSMEG_0135|M.smegmatis_MC2_155 DGQFVRAAGVEVGKVKSVDLINGGEQAEVKFTVERSLPLFQETTAAIRYQ
TH_3551|M.thermoresistible__bu AGQFVRAAGVEVGKVSKVELIDGGQRVRVDFNVDRSLPLFQDTTATIRYL
Mb0605|M.bovis_AF2122/97 AGQFVRAAGVEVGKVAKVTLIDGDKQVLVDFTVDRSLSLDQATTASIRYL
MAB_4152c|M.abscessus_ATCC_199 SGQKVRIAGVPVGRVKNVSLNRDNS-VEVTFDVDSKYQLYSSSRAIIRYE
** ** :** :*:* : * .. . * * :: . * . : * :**
MLBr_02590|M.leprae_Br4923 DLIGNRYLELKHGEGQGSEKIMPAGGLIPLSRTSPALDLDALIGGFKPLF
MAV_5014|M.avium_104 DLIGNRYLELKRGQGEGADKVLPPGGFIPLSRTQPALDLDALIGGFKPLF
MMAR_0413|M.marinum_M DLIGNRYLELKRGEGDGSDRIMPPGGFIPLSRTSPALDLDALIGGFKPVF
MUL_1063|M.ulcerans_Agy99 DLIGNRYLELKRGEGDGSDRIMPPGGFIPLSRTSPALDLDALIGGFKPVF
Rv0170|M.tuberculosis_H37Rv DLIGNRYVELKRGEGKGANDLLPPGGLIPLSRTSPALDLDALIGGFKPVF
Mvan_0135|M.vanbaalenii_PYR-1 NLIGDRYLELARGE---SNTRMAAGGTIPIERTQPALDLDALIGGFRPVF
Mflv_0710|M.gilvum_PYR-GCK NLIGDRYLELARGD---SNTRLAAGGTIPVERTQPALDLDALIGGFRPVF
MSMEG_0135|M.smegmatis_MC2_155 DLIGNRYLELKRGD---SDQILPPGSTIPVERTEPALDLDALVGGFRPLF
TH_3551|M.thermoresistible__bu NLIGDRYLELKRGN---SNERLPAGGEIPLERTQPALDLDALVGGFRPLF
Mb0605|M.bovis_AF2122/97 NLIGDRYLELGRGH---SGQRLAPGATIPLEHTHPALDLDALLGGFRPLF
MAB_4152c|M.abscessus_ATCC_199 NLVGDRYLEITAGPG--ELHKLPDGGTLDKEHTQPALDLDALLGGLRPVL
:*:*:**:*: * :. *. : .:* ********:**::*::
MLBr_02590|M.leprae_Br4923 RALDPDKINTIASAIVAAFQGQGGTINDILDQTAQLTTAIGERDQAIGEV
MAV_5014|M.avium_104 RALDPQKVNTIATALVTVFQGQGGTINDILDQTAQLTSQLGERDQAIGEV
MMAR_0413|M.marinum_M RALDPDKVNTIASALVTVFQGQGGTINDILDQTAQLTSQLAERDQAIGEV
MUL_1063|M.ulcerans_Agy99 RALDPDKVNTIASALVTVFQGQGGTINDILDQTAWLTSQLAERDQAIGEV
Rv0170|M.tuberculosis_H37Rv RALDPAKVNNIANALITVFQGQGGTINDILDQTAQLTSQIAERDQAIGEV
Mvan_0135|M.vanbaalenii_PYR-1 QSLEPEKVNTIAQSIITVFQGQGGTINDILDQTASLTSALADRDQAIGEV
Mflv_0710|M.gilvum_PYR-GCK QSLDPEKVNTIAQSLITVFQGQGGTINDILDQTASLTSALADRDQAIGEV
MSMEG_0135|M.smegmatis_MC2_155 RSLEPEKVNTIATSLITIFQGQGGTINDILDQTAQLTASLADRDQAIGEV
TH_3551|M.thermoresistible__bu RALDAEKVNTIAQSIITVFQGQGGTINDILDQTAQLTATLADRDQAIGEV
Mb0605|M.bovis_AF2122/97 QTLDPDKVNSIASSIITVFQGQGATINDILDQTASLTATLADRDHAIGEV
MAB_4152c|M.abscessus_ATCC_199 KGFDAAKVNEISNAFIQILQGQGGTLSQLLGDTSSFTSGLAERDQLIGDV
: ::. *:* *: ::: :****.*:.::*.:*: :*: :.:**: **:*
MLBr_02590|M.leprae_Br4923 VKNLNVVLDTTVRHRKEFDQTVNNLEILITGLKDHGDQLAGSFAHISNAA
MAV_5014|M.avium_104 IKNLNTVLDTTVRHRQQFDQTINNLEVLITGLKDHGDQLAGGTAHISNAA
MMAR_0413|M.marinum_M IKNLNTVLDATVRHRKDFDQTVNNLEVLITGLNEHRDDLSGGIAHVSNAA
MUL_1063|M.ulcerans_Agy99 IKNLNTVLDATVRHRKDFDQTVNNLEVLITGLNEHRDDLSGGIAHVSNAA
Rv0170|M.tuberculosis_H37Rv VKNLNIVLDTTVKHRKEFDETVNNLENLITGLRNHSDQLAGGLAHISNGA
Mvan_0135|M.vanbaalenii_PYR-1 ITNLNTVLDTTVRHQQEFDDTVKNFEVLITGLKNRADPIATSVADISDAA
Mflv_0710|M.gilvum_PYR-GCK VTNLNTVLDTTVRHQQEFDDTVKNFEVLITGLKNRADPLAESVADISDAA
MSMEG_0135|M.smegmatis_MC2_155 IKNLNTVLDTTVRHQKQFDETLVNFETLITGLKNRADPIATSVADISDAA
TH_3551|M.thermoresistible__bu IRNLNTVLETTVRHQKEFDETIHNFEVLITGLRNRADPIAESTANISNAA
Mb0605|M.bovis_AF2122/97 VNNLNTVLATTVKHQTEFDRTVDKLEVLITGLKNRADPLAAAAAHISSAA
MAB_4152c|M.abscessus_ATCC_199 INHLNEVLATVDSKSTQFSSSVDQLQQLISGLAQQRDVVAGALPPLASTA
: :** ** :. : :*. :: ::: **:** :: * :: . . ::. *
MLBr_02590|M.leprae_Br4923 GTVANLLAEDHALLHKSINYLDGIQQPLIDQRLQLEDYLHKLPTVLNQIG
MAV_5014|M.avium_104 GTVADLLAEDRSLLHKTLNYLDAVQQPLIDQQDQLQDYLKKVPTALNMIG
MMAR_0413|M.marinum_M GTVADLLGEDRALLHKTVNYLDAVQQPLIDQRQELADFLHKVPTALNMIG
MUL_1063|M.ulcerans_Agy99 GTVADLLGEDRALLHKTVNYLDAVQQPLIDQRQELADFLHKVPTALNMIG
Rv0170|M.tuberculosis_H37Rv GTVADLLAENRTLVRKAVSYLDAIQQPVIDQRVELDDLLHKTPTALTALG
Mvan_0135|M.vanbaalenii_PYR-1 GTIGDLLADNRPLLKDTVSKLEILNQPLVDQRDQLNDLLVKLPDALAIIG
Mflv_0710|M.gilvum_PYR-GCK GTIGDLLADNRPLLQSTISKLEILNQPLVDQKDQLNQLLEQIPDALAIIG
MSMEG_0135|M.smegmatis_MC2_155 GSLADLLSDNRPLLKDTIGYLDVIQAPLVEQKQEVSDILVQMPQALKIIG
TH_3551|M.thermoresistible__bu GTLADVLAQNRPLLDNSIDHLEAVQGPLVEQSAELNNILVQLPTALKTIG
Mb0605|M.bovis_AF2122/97 GTLADLLGADRPLLHSSFGHLEGIQQPLIDELAELDHVLGKLPDAYRIIG
MAB_4152c|M.abscessus_ATCC_199 SSLESVLKDTRPYIKGTIEQARQLATRVDERKADVNVVVENLAENYLRLN
.:: .:* :. : :. : : :. :: : : . :.
MLBr_02590|M.leprae_Br4923 RTIGSYGDFVNFYSCDITLKINGLQPGGPVRTVRLFQQPT-GRCTPQ--
MAV_5014|M.avium_104 RAIGSYGDFVNFYACDITLKINGLQAGGPVRTVRLFQQPT-GRCTPQ--
MMAR_0413|M.marinum_M RAIGSYGDFVNFYSCDISLKINGLQPGGPVRTVRLFSQPT-GRCAPQ--
MUL_1063|M.ulcerans_Agy99 RAIGSYGDFVNFYSCDISLKINGLQPGGPVRTVRLFSQPT-GRCAPQ--
Rv0170|M.tuberculosis_H37Rv RANGTYGDFQNFYLCDLQIKWNGFQAGGPVRTVKLFSQPT-GRCTPQ--
Mvan_0135|M.vanbaalenii_PYR-1 RSGGVYGDFFNFYACDVTLKLNGLQPGGPVRTVKVWSQPS-GRCTPQ--
Mflv_0710|M.gilvum_PYR-GCK RSGGIYGDFFNFYACDVTLKLNGLQPGGPVRTVRVWSQPT-GRCTPQ--
MSMEG_0135|M.smegmatis_MC2_155 RAGGIYGDFFNFYACDLTLKLNGLQPGGPVRTVRITTQPS-GRCTPK--
TH_3551|M.thermoresistible__bu RAGGVYGDFFNFYACDISLKLNGLQPGGPVRTVKITTQPS-GRCTPQ--
Mb0605|M.bovis_AF2122/97 RAGGIYGDFFNFYLCDISLKVNGLQPGGPVRTVKLFGQPT-GRCTPQ--
MAB_4152c|M.abscessus_ATCC_199 -ALGAYGSFFNIYYCSIRIKVNGPVGTDWLIPFGGPPDPSKGRCAFKNE
: * **.* *:* *.: :* ** . : .. :*: ***: :