For questions or suggestions e-mail us at: ioerger@cs.tamu.edu

M. thermoresistible (build 8) TH_4123 (-)

annotation: virulence factor Mce family protein
coordinates: 367416 - 368384
length: 323

aa seq not available

Operon Prediction Model: Genebank

Paralogs

species id gene e-value identity (len) annotation
M. thermoresistible (build 8) TH_4123 - - 100% (323) virulence factor Mce family protein
M. thermoresistible (build 8) TH_3213 - e-116 64.35% (317) PUTATIVE virulence factor Mce family protein
M. thermoresistible (build 8) TH_3222 - e-113 63.04% (322) PUTATIVE virulence factor Mce family protein

Closest Orthologs (e-value cutoff: 1e-4)

species id gene e-value identity (len) annotation
M. bovis AF2122 / 97 Mb0605 mce2B 1e-77 49.38% (324) MCE-family protein MCE2B
M. gilvum PYR-GCK Mflv_2102 - 1e-120 65.12% (324) virulence factor Mce family protein
M. tuberculosis H37Rv Rv1967 mce3B 1e-110 62.07% (319) MCE-family protein MCE3B
M. leprae Br4923 MLBr_02590 mce1B 1e-72 45.09% (326) putative secreted protein
M. abscessus ATCC 19977 MAB_4152c - 4e-54 36.68% (319) MCE-family protein
M. marinum M MMAR_4052 mce3B_1 1e-110 59.88% (324) MCE-family protein Mce3B_1
M. avium 104 MAV_2533 - 1e-111 61.80% (322) virulence factor Mce family protein
M. smegmatis MC2 155 MSMEG_0347 - 1e-113 62.11% (322) virulence factor Mce family protein
M. ulcerans Agy99 MUL_3919 mce3B_1 1e-110 59.88% (324) MCE-family protein Mce3B_1
M. vanbaalenii PYR-1 Mvan_0364 - 1e-117 63.98% (322) virulence factor Mce family protein

CLUSTAL 2.0.9 multiple sequence alignment


Mb0605|M.bovis_AF2122/97            --MKTTGTTIKLGIVWLVLSVFTVMIIVVFGQVRFHHT-TGYSAVFTHVS
MLBr_02590|M.leprae_Br4923          --MKLTGTVVRLSIFSLVLLLFTVMIIVVFGQMRFGRT-NGYTAEFTNIS
TH_4123|M.thermoresistible__bu      --------------------MGTFGLLMIFAELRFYGE-EVYRAEFGDVS
MSMEG_0347|M.smegmatis_MC2_155      MNKEVLSTLIRVSAFLTVCAVGVFALFSIFADLRFGER-KQYTAQFSDIS
MMAR_4052|M.marinum_M               MRARLIRDAIRLGTFLLVCFLGVIGLFAVFGQLRFGEKTSTYKAEFSNVT
MUL_3919|M.ulcerans_Agy99           MRARLIRDAIRLGTFLLVCFLGVIGLFAVFGQLRFGEKTSTYKAEFSNVT
Mflv_2102|M.gilvum_PYR-GCK          MSVSIRRDATRLGAFLAVCLLGVFGLFAVFGQMRFGEKTQQYRAEFVNVT
MAV_2533|M.avium_104                MKENLTGTLWRLAIYVVVSVLGMFTLVAVFGQLRFQSE-KTYKAQFANVS
Rv1967|M.tuberculosis_H37Rv         MRENLGGVVVRLGVFLAVCLLTAFLLIAVFGEVRFGDG-KTYYAEFANVS
Mvan_0364|M.vanbaalenii_PYR-1       MRGNFAAAAWRLGIFLAVCALGTFVLLSVFAQFRFGDG-KTYQAEFSNVS
MAB_4152c|M.abscessus_ATCC_199      ---MKRATQIKVIVFTVVMLLVAAGLIITFGEFRFGSG-KRYHAMFSTAS
                                                        :    :.  *.:.**      * * *   :

Mb0605|M.bovis_AF2122/97            GLRAGQFVRAAGVEVGKVAKVTLIDGDKQVLVDFTVDRSLSLDQATTASI
MLBr_02590|M.leprae_Br4923          GLRTGQFVRASGVEVGKVNSVALINGGTRVRVKFNVDRSVPLYQSTTAQI
TH_4123|M.thermoresistible__bu      GLETGDFVRIAGVEVGKVKAIDLDD-NGIVHVEFSANSAAVLTDKTRAAI
MSMEG_0347|M.smegmatis_MC2_155      GLKEGDFVRIAGVEVGQVQKVSMDE-NALVLVEFAMEDSVELTSTSTAVI
MMAR_4052|M.marinum_M               GLEQNDFVRIAGVEVGQVKKVAIQP-DTTALVEFTADSSVVLTQGSRAVI
MUL_3919|M.ulcerans_Agy99           GLEQNDFVRIAGVEVGQVKKVAIQP-DTTALVEFTADSSVVLTQGSRAVI
Mflv_2102|M.gilvum_PYR-GCK          GLETNDFVRIAGVEVGKVENVEIQP-DTTAVVEFTADDSVVLTQGSRAVI
MAV_2533|M.avium_104                GLEGGNFVRIAGVEVGKVKNITVEP-DSTVLVEFTAAEKVVLTEGTRAAI
Rv1967|M.tuberculosis_H37Rv         NLRTGKLVRIAGVEVGKVTRISINP-DATVRVQFTADNSVTLTRGTRAVI
Mvan_0364|M.vanbaalenii_PYR-1       GLKDGDLVRIAGVEVGKVKSITVGS-DAVVTVSFDTDDTVVLTDGTRAAI
MAB_4152c|M.abscessus_ATCC_199      DLRSGQKVRIAGVPVGRVKNVSLNR-DNSVEVTFDVDSKYQLYSSSRAII
                                    .*. .. ** :** **:*  : :   .  . * *       *   : * *

Mb0605|M.bovis_AF2122/97            RYLNLIGDRYLELGRG---HSGQRLAPGATIPLEHTHPALDLDALLGGFR
MLBr_02590|M.leprae_Br4923          RYLDLIGNRYLELKHGEGQGSEKIMPAGGLIPLSRTSPALDLDALIGGFK
TH_4123|M.thermoresistible__bu      RWADMIGGRYLSLEEPE--RGSRPLQPGETIPRDRTAPALDLDALIGGFR
MSMEG_0347|M.smegmatis_MC2_155      RYDNLIGGRYLELKQGE--EPGAVLQAGATIPLARTRPALDLDELIGGFR
MMAR_4052|M.marinum_M               RYDDLIGGRYLALEEGA--GSPKQLKPGDTIPMTHTSPALDLDALIGGFR
MUL_3919|M.ulcerans_Agy99           RYDDLIGGRYLALEEGA--GSPKQLKPGDTIPMTHTSPALDLDALIGGFR
Mflv_2102|M.gilvum_PYR-GCK          RYDDLIGGRYLALEEGA--GGTQKLNPGGTIPLARTSPALDLDALIGGFR
MAV_2533|M.avium_104                RFADLTGGRYVALEEGA--GNIRRLSPGATIPLARTEPALDLDALIGGFR
Rv1967|M.tuberculosis_H37Rv         RYDNLFGDRYLALEEGA--GGLAVLRPGHTIPLARTQPALDLDALIGGFK
Mvan_0364|M.vanbaalenii_PYR-1       RYDNLFGGRYLALEEGV--GGLHEMSPGHTIPLARTEPALDLDSLIGGFR
MAB_4152c|M.abscessus_ATCC_199      RYENLVGDRYLEITAGP--GELHKLPDGGTLDKEHTQPALDLDALLGGLR
                                    *: :: *.**: :           :  *  :   :* ****** *:**::

Mb0605|M.bovis_AF2122/97            PLFQTLDPDKVNSIASSIITVFQGQGATINDILDQTASLTATLADRDHAI
MLBr_02590|M.leprae_Br4923          PLFRALDPDKINTIASAIVAAFQGQGGTINDILDQTAQLTTAIGERDQAI
TH_4123|M.thermoresistible__bu      PLFRALDPDQVNALSHQLIEAFQGQGSTISFLLRNTAEVTRTLADRDQLI
MSMEG_0347|M.smegmatis_MC2_155      PLFKALDPDQVNALSTQLVQVFQGQGATISSFLDQTAAMTSTLADRDQLI
MMAR_4052|M.marinum_M               PLLKALDPEQVNALSGQLIRALQGEGATINSFLAQTAALTTTLADRDQLI
MUL_3919|M.ulcerans_Agy99           PLLKALDPDQVNALSGQLIRALQGEGATINSFLAQTAALTTTLADRDQLI
Mflv_2102|M.gilvum_PYR-GCK          PLFRALDPDQINALSGQLISALQGQGGTINSFLAQTAALTSTLADRDQLI
MAV_2533|M.avium_104                PLFRALDPDQVNKLTGQLIAAFQGQGGTIGSFLTQAAALTNTLADRDHLI
Rv1967|M.tuberculosis_H37Rv         PLFRALNPEQVNALSEQLLHAFAGQGPTIGSLLAQSAAVTNTLADRDRLI
Mvan_0364|M.vanbaalenii_PYR-1       PLFRALDPEQVNELSAQLIGALQGQGPTIGSFLEQAAAVTNTLADRDQLI
MAB_4152c|M.abscessus_ATCC_199      PVLKGFDAAKVNEISNAFIQILQGQGGTLSQLLGDTSSFTSGLAERDQLI
                                    *::: ::. ::* ::  ::  : *:* *:. :* ::: .*  :.:**: *

Mb0605|M.bovis_AF2122/97            GEVVNNLNTVLATTVKHQTEFDRTVDKLEVLITGLKNRADPLAAAAAHIS
MLBr_02590|M.leprae_Br4923          GEVVKNLNVVLDTTVRHRKEFDQTVNNLEILITGLKDHGDQLAGSFAHIS
TH_4123|M.thermoresistible__bu      GEVITNLNTVLGTFAEEHEKFDQSVDSLSQLIEGLHDRRTDISNAVAHID
MSMEG_0347|M.smegmatis_MC2_155      GEVIGNLDVLLGSLGEQSHQFDKAVNSLSELVAGLSARRTDITNAIANSD
MMAR_4052|M.marinum_M               GDVIINLNVVLGSLGDQNKQFAKAVDALAELMEGLQARKEDITKGVAYTN
MUL_3919|M.ulcerans_Agy99           GDVIINLNVVLGSLGDQNKQFAKAVDALAELMEGLQARKEDITKGMAYTN
Mflv_2102|M.gilvum_PYR-GCK          GEVIINLNTVLGSLGDQSDQFAKAVDSLSQLVEGLSDRRQEISDGLAYTN
MAV_2533|M.avium_104                GQVIVNLNTVLGSLGGQSGQFARAVDSLSELVAGLEARKQDISNGMAYAN
Rv1967|M.tuberculosis_H37Rv         GQVITNLNVVLGSLGAHTDRLDQAVTSLSALIHRLAQRKTDISNAVAYTN
Mvan_0364|M.vanbaalenii_PYR-1       GEVVVNLNTVLGSIGQQSDRFDTAVTSLSELVHGLAERRTDISDAVAHTN
MAB_4152c|M.abscessus_ATCC_199      GDVINHLNEVLATVDSKSTQFSSSVDQLQQLISGLAQQRDVVAGALPPLA
                                    *:*: :*: :* :   .  .:  :*  *  *:  *  :   :: . .   

Mb0605|M.bovis_AF2122/97            SAAGTLADLLGADRPLLHSSFGHLEGIQQPLIDELAELDHVLGKLPDAYR
MLBr_02590|M.leprae_Br4923          NAAGTVANLLAEDHALLHKSINYLDGIQQPLIDQRLQLEDYLHKLPTVLN
TH_4123|M.thermoresistible__bu      GAAGTIGELLVQARPPLKKVVHETDRAAGIAVGDHEYLDNFLNTLPDTYR
MSMEG_0347|M.smegmatis_MC2_155      NAATEIADLLAQARPPLQNVVTQADRAAAIAVADHEYLDNILNTLPDKYR
MMAR_4052|M.marinum_M               AAASSIADLLSQARPPLTKTVQETDRASAIVLADHEYFDNLINTLPDAYQ
MUL_3919|M.ulcerans_Agy99           AAASSIADLLSQARPPLAKTVQETDRASAIVLADHEYFDNLINTLPDAYQ
Mflv_2102|M.gilvum_PYR-GCK          AAAGSIADFLTEARPPLKKTIDETDRAAGIVVADHEYFDNLINTLPDAYQ
MAV_2533|M.avium_104                AAAGSITDLLAQARPPVKKVVHEADRTAGTMLADREWLEKYLDHWPDAFK
Rv1967|M.tuberculosis_H37Rv         AAAGSVADLLSQARAPLAKVVRETDRVAGIAAADHDYLDNLLNTLPDKYQ
Mvan_0364|M.vanbaalenii_PYR-1       SATASLADLLAATRPPLQRVVHETDRAAAIAVADHEYLDNLLNTLPDRYQ
MAB_4152c|M.abscessus_ATCC_199      STASSLESVLKDTRPYIKGTIEQARQLATRVDERKADVNVVVENLAENYL
                                     ::  : ..*   :. :   .                .:  :   .    

Mb0605|M.bovis_AF2122/97            IIGRAGGIYGDFFNFYLCDISLKVNGLQPGGPVRTVKLFGQP---TGRCT
MLBr_02590|M.leprae_Br4923          QIGRTIGSYGDFVNFYSCDITLKINGLQPGGPVRTVRLFQQP---TGRCT
TH_4123|M.thermoresistible__bu      IIARQ-GIHGDFFSFYLCDLVLKLNGK--GGNPVYVKLAGQD---SGRCA
MSMEG_0347|M.smegmatis_MC2_155      VLGRQ-AMYGDYFSFYLCDLILKLNGK--GGQPVYVKLAEQV---TGRCA
MMAR_4052|M.marinum_M               ALSRQ-GIYGDFFSFYLCDVVLKLNGR--GGQPVYVKVAGQP---TGRCA
MUL_3919|M.ulcerans_Agy99           ALSRQ-GIYGDFFSFYLCDVVLKLNGR--GGQPVYVKVAGQP---TGRCA
Mflv_2102|M.gilvum_PYR-GCK          VLARQ-GIYGDFFSFYLCDIVLKLNGK--GGQPVYVKVAGQS---SGRCA
MAV_2533|M.avium_104                ILNRQ-GLYGDFFSFYLCDIVLKLNGK--GGQPVYVKVAGQA---SGRCT
Rv1967|M.tuberculosis_H37Rv         ALVRQ-GMYGDFFAFYLCDVVLKVNGK--GGQPVYIKLAGQD---SGRCA
Mvan_0364|M.vanbaalenii_PYR-1       ALGRQ-GMYGDFFSFYLCEIVLKLNGK--GGQPVYVKVAGQD---SGRCT
MAB_4152c|M.abscessus_ATCC_199      RLNAL-GAYGSFFNIYYCSIRIKVNGP--VGTDWLIPFGGPPDPSKGRCA
                                     :    . :*.:. :* *.: :*:**    *    : .       .***:

Mb0605|M.bovis_AF2122/97            PQ--
MLBr_02590|M.leprae_Br4923          PQ--
TH_4123|M.thermoresistible__bu      PQ--
MSMEG_0347|M.smegmatis_MC2_155      PK--
MMAR_4052|M.marinum_M               PR--
MUL_3919|M.ulcerans_Agy99           PR--
Mflv_2102|M.gilvum_PYR-GCK          PR--
MAV_2533|M.avium_104                PR--
Rv1967|M.tuberculosis_H37Rv         PK--
Mvan_0364|M.vanbaalenii_PYR-1       PR--
MAB_4152c|M.abscessus_ATCC_199      FKNE
                                     :

species	id	gene	e-value	identity (len)	annotation
M. thermoresistible (build 8)	TH_4123	-	-	100% (323)	virulence factor Mce family protein
M. thermoresistible (build 8)	TH_3213	-	e-116	64.35% (317)	PUTATIVE virulence factor Mce family protein
M. thermoresistible (build 8)	TH_3222	-	e-113	63.04% (322)	PUTATIVE virulence factor Mce family protein