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M. thermoresistible (build 8) TH_2529 (-)

annotation: enoyl-CoA hydratase/isomerase
coordinates: 278319 - 279086
length: 256

aa seq not available

Operon Prediction Model: Genebank

Paralogs
speciesidgenee-valueidentity (len)annotation
M. thermoresistible (build 8)TH_2529--100% (256)enoyl-CoA hydratase/isomerase
M. thermoresistible (build 8)TH_4638-4e-6248.77% (244) PUTATIVE putative enoyl-CoA hydratase/isomerase family protein
M. thermoresistible (build 8)TH_3045-2e-6147.24% (254) PUTATIVE Enoyl-CoA hydratase/isomerase

Closest Orthologs (e-value cutoff: 1e-4)
speciesidgenee-valueidentity (len)annotation
M. bovis AF2122 / 97Mb2698echA151e-2630.67% (238) enoyl-CoA hydratase
M. gilvum PYR-GCKMflv_2395-2e-9968.77% (253) enoyl-CoA hydratase/isomerase
M. tuberculosis H37RvRv0222echA14e-2839.15% (212) enoyl-CoA hydratase
M. leprae Br4923MLBr_01241-2e-2331.10% (209) enoyl-CoA hydratase
M. abscessus ATCC 19977MAB_4588c-2e-2336.57% (216) enoyl-CoA hydratase/isomerase
M. marinum MMMAR_4790-1e-11479.22% (255) enoyl-CoA hydratase
M. avium 104MAV_0867-1e-10976.80% (250) enoyl-CoA hydratase/isomerase family protein
M. smegmatis MC2 155MSMEG_4873-1e-12686.90% (252) enoyl-CoA hydratase/isomerase
M. ulcerans Agy99MUL_0359-1e-11479.61% (255) enoyl-CoA hydratase
M. vanbaalenii PYR-1Mvan_4253-1e-10069.69% (254) enoyl-CoA hydratase/isomerase

CLUSTAL 2.0.9 multiple sequence alignment


TH_2529|M.thermoresistible__bu      -------MYDMPPEIDVR----------ADGDIRIITLNRPDALNAVNDP
MSMEG_4873|M.smegmatis_MC2_155      ----------MPDEIEVR----------AEGDIRVITLNRPEALNAVNDS
MMAR_4790|M.marinum_M               -------MYDMPTEIDVR----------AEGALRIITLNRPDALNAVNDN
MUL_0359|M.ulcerans_Agy99           -------MYDMPTEIDVR----------AEGALRIITLNRPDALNAVNDN
MAV_0867|M.avium_104                -------MYDMPTEIDVR----------ADGALRIITLNRPDSLNSVNDD
Mflv_2395|M.gilvum_PYR-GCK          -------MYGMPDEIDVT----------ADGDLRIITLNRPDDLNAVNDN
Mvan_4253|M.vanbaalenii_PYR-1       -------MYGMPEEIDVR----------ADGALRIITLNRPDDLNAVNDN
Rv0222|M.tuberculosis_H37Rv         -MSSESDAANTEPEVLVE----------QRDRILIITINRPKAKNAVNAA
MAB_4588c|M.abscessus_ATCC_199      ----------MADEVLIE----------QRDRVLLITINRPDARNAVNRA
Mb2698|M.bovis_AF2122/97            MPVTYDDFPSLRCEIHDQ----------PGHEGVLELVLDSPGLNSVGPH
MLBr_01241|M.leprae_Br4923          --MSQTDASCTIAELPYRSVTDLVVLDFPRPEVALITLNRPGRMNSMALD
                                                 *:                   :  :  .   *::   

TH_2529|M.thermoresistible__bu      LHEGLAKLWDRLSEDYDARAAVLTGAGRAFSAGGDYAYLAELGEDP----
MSMEG_4873|M.smegmatis_MC2_155      LHEGLAHLWTRLSEDYDARAAVITGAGRAFSAGGDFAYLQELGEDP----
MMAR_4790|M.marinum_M               LHVGLAGLWRRLSEDRSARAAVLTGAGRAFSAGGDFAYLAELSQDA----
MUL_0359|M.ulcerans_Agy99           LHVGLAGLWRRLSEDRSARAAVLTGAGRAFSAGGDFAYLAELAQDA----
MAV_0867|M.avium_104                LHVGLARLWQRLTDDPTARAAVITGAGRAFSAGGDFGYLKELSADA----
Mflv_2395|M.gilvum_PYR-GCK          LHVGLAKIWEELNEDPGARAAVITGAGRAFSAGGDFHYLDELRRDE----
Mvan_4253|M.vanbaalenii_PYR-1       LHVGLAKIWEELNEDAGARAAVITGAGRAFSAGGDFNYLDELRNDE----
Rv0222|M.tuberculosis_H37Rv         VSRGLADAMDQLDGDAGLSVAILTGGGGSFCAGMDLKAFARG--------
MAB_4588c|M.abscessus_ATCC_199      VSQGLAAAADQLDSSADLSVAIITGAGGNFCAGMDLKAFVSG--------
Mb2698|M.bovis_AF2122/97            MHRDLADIWPVIDRDPAVRVVLVRGEGKAFSSGGSFDLIAETIGDY----
MLBr_01241|M.leprae_Br4923          LMKSLKQVLKRITYDHSVRVVVLTGAGRGFCSGADQKFTAPVPQVEGLTQ
                                    :  .*      :  .    ..:: * *  *.:* .               

TH_2529|M.thermoresistible__bu      -RLRAKTLQHGREIVLGMTRCRVPVVAAVNGPAVGLGCSLVALSDIVYIA
MSMEG_4873|M.smegmatis_MC2_155      -KLRAKTILHGREIVLGMTRCRVPVVAAVNGPAVGLGCSLVALSDIVYIA
MMAR_4790|M.marinum_M               -DLRAKTIAHGRDIVLGMARCRVPVVAAVNGPAVGLGCSLVALSDIVYIA
MUL_0359|M.ulcerans_Agy99           -DLRAKTIAHGRDIVLGMARCRVPVVAAVNGPAVGLGCSLVALSDIVYIA
MAV_0867|M.avium_104                -DLRAKTIRDGREIVLGMARCRIPVVAAVNGPAVGLGCSLVALSDIVYIA
Mflv_2395|M.gilvum_PYR-GCK          -ALRQKTIKHGRDLVIGMVRCRIPVIAAVNGPAVGLGCSLAALSDVVYIA
Mvan_4253|M.vanbaalenii_PYR-1       -ALRQKTIKHGRDLVIGMVRCRIPVVAAVNGPAVGLGCSLAALSDVVYIA
Rv0222|M.tuberculosis_H37Rv         ----ENVVVEGRGLGFTERPPTKPLIAAVEGYALAGGTELALAADLIVAA
MAB_4588c|M.abscessus_ATCC_199      ----EAVLSE-RGLGFTNVPPRKPIIAAVEGFALAGGTELVLSCDLVVAG
Mb2698|M.bovis_AF2122/97            -QGRLRIMREARDLVLNLVNFDKPVVSAIRGPAVGAGLVVALLADISVAG
MLBr_01241|M.leprae_Br4923          PVRALRAMELLEEVILALRRLHQPVIAAINGPAIGGGLCLALAADVRVAS
                                           :   . : :       *:::*:.* *:. *  :.  .*:   .

TH_2529|M.thermoresistible__bu      PDAYLADPHVQVGLVAADGGP-ITWPLHISLLLAKEYALTGARIPAQRAV
MSMEG_4873|M.smegmatis_MC2_155      PQAYLADPHVQVGLVAADGGP-ITWPLHISLLLAKEYALTGARIPAQRAV
MMAR_4790|M.marinum_M               PDAYLADPHVQVGLVAADGGP-LTWPLHISLMLAKEYALTGQRIAAQRAV
MUL_0359|M.ulcerans_Agy99           PDAYLADPHVQVGLVAADGGP-LTWPLHISLMLAKEYALTGQRIAAQRAV
MAV_0867|M.avium_104                ENAYLADPHVQVGLVAADGGP-LTWPLHISLLLAKEYALTGTRISAQRAV
Mflv_2395|M.gilvum_PYR-GCK          ENAFFADPHVSIGLVAADGGP-LVWGSQISLLQAKEFALTGVRIKAQKAV
Mvan_4253|M.vanbaalenii_PYR-1       ENAFFADPHVSIGLVAADGGP-LVWGSQISLLQAKEFALTGVRIKAQRAV
Rv0222|M.tuberculosis_H37Rv         RDSAFGIPEVKRGLVAGGGGL-LRLPERIPYAIAMELALTGDNLPAERAH
MAB_4588c|M.abscessus_ATCC_199      RSAKFGIPEVKRGLVAGAGGL-LRLPNRIPYQVAMELALTGESFTAEDAA
Mb2698|M.bovis_AF2122/97            RAAKIIDGHTKLGVAAGDHAA-ICWPLLVGMAKAKYYLLTCEPLSGEEAE
MLBr_01241|M.leprae_Br4923          TRAYFRAAGINNGLSASELGLSYLLPRAVGSSRAFEIMLSGRDVGAEEAE
                                      : :     . *: *.  .        :    *    *:   . .: * 

TH_2529|M.thermoresistible__bu      ELGLANHLSED--PVADAVAAARKMSRMPRQALEATKRLLNIHMERAVMA
MSMEG_4873|M.smegmatis_MC2_155      ELGLANHLSDD--PVAEAIEAAQKMAKLPRQSLEATKRLLNLHMEQAVLA
MMAR_4790|M.marinum_M               ELGLVNHVAAD--PVAEAVACAQRIMKLPQQAVESTKRVLNIHLERAVLA
MUL_0359|M.ulcerans_Agy99           ELGLANHVAAD--PVAEAVACAQRIVKLPQQAVESTKRVLNIHLERAVLA
MAV_0867|M.avium_104                ELGLANHVADD--PVAEAIACAQKILELPQQAVESTKRVLNIHLERAVLA
Mflv_2395|M.gilvum_PYR-GCK          ELGLANHVVDD--PVGEAIACAKKIMALPQQAVEATKRLMNIQLEKSVMA
Mvan_4253|M.vanbaalenii_PYR-1       ELGLANHVVDD--PVAEAIACAKKLIELPQQAVEATKRLMNIQLEKSVMA
Rv0222|M.tuberculosis_H37Rv         ELGLVNVLAEPGTALDAAIALAEKITANGPLAVVATKRIITESRGWSPDT
MAB_4588c|M.abscessus_ATCC_199      KYGFINRLVDDGQALDTALELAAKITANGPLAVAATKRIIIESASWAPEE
Mb2698|M.bovis_AF2122/97            RIGLVSICVDDDDVLPTATRLAERLAAGAQNAIRWTKRSLN-HWYRMFGP
MLBr_01241|M.leprae_Br4923          QIGLVSYRVSDDRLLDTCYSIAARMATFSRSGTELTKRALWGGLDAASLD
                                    . *: .        :  .   * ::      .   *** :          

TH_2529|M.thermoresistible__bu      TLDYG--NTAEAQSFETEDFRNIVAGLNARRN--------------
MSMEG_4873|M.smegmatis_MC2_155      TLDFG--NTAEEQSFRTEDFKAIVAGLNARKN--------------
MMAR_4790|M.marinum_M               SLDYA--LSAEHQSFTTEDFRSIVTRLTAPKN--------------
MUL_0359|M.ulcerans_Agy99           SLDYA--LSAEHQSFTTEDFRSIVTRLTAPKN--------------
MAV_0867|M.avium_104                SLDYA--LSAESQSFVTEDFRSIVTKL-ADKN--------------
Mflv_2395|M.gilvum_PYR-GCK          SLDYA--NLAEYVSFGTADFNRIVDGLIAKN---------------
Mvan_4253|M.vanbaalenii_PYR-1       SLDYA--NLAEYVSFGTADFNKIVDGLIAKK---------------
Rv0222|M.tuberculosis_H37Rv         MFAEQ--MKILVPVFTSNDAKEGAIAFAERRRPRWTGT--------
MAB_4588c|M.abscessus_ATCC_199      AFAKQ--GEILMPIFVSEDAKEGAKAFAEKRAPVWQGK--------
Mb2698|M.bovis_AF2122/97            AFETS--LGLEFIGFGGPDVREGLAAHREKRPARFGADPDPGAGS-
MLBr_01241|M.leprae_Br4923          KHMQSESLAQLFIALHTSNFEEAAAPCTEKRPTVLVDARGCATSPG
                                                  :   : .         .