For questions or suggestions e-mail us at: ioerger@cs.tamu.edu

M. thermoresistible (build 8) TH_3045 (-)

annotation: Enoyl-CoA hydratase/isomerase
coordinates: 1451046 - 1451822
length: 259

aa seq not available

Operon Prediction Model: Genebank

Paralogs

species id gene e-value identity (len) annotation
M. thermoresistible (build 8) TH_3045 - - 100% (259) Enoyl-CoA hydratase/isomerase
M. thermoresistible (build 8) TH_3165 - 1e-68 50.41% (242) PUTATIVE putative enoyl-CoA hydratase
M. thermoresistible (build 8) TH_3065 - 6e-62 44.80% (250) PUTATIVE enoyl-CoA hydratase

Closest Orthologs (e-value cutoff: 1e-4)

species id gene e-value identity (len) annotation
M. bovis AF2122 / 97 Mb2698 echA15 3e-37 36.19% (257) enoyl-CoA hydratase
M. gilvum PYR-GCK Mflv_2395 - 1e-59 46.91% (243) enoyl-CoA hydratase/isomerase
M. tuberculosis H37Rv Rv2679 echA15 3e-37 36.19% (257) enoyl-CoA hydratase
M. leprae Br4923 MLBr_02402 - 4e-26 32.17% (230) enoyl-CoA hydratase
M. abscessus ATCC 19977 MAB_0836c - 1e-22 29.37% (252) putative enoyl-CoA hydratase/isomerase
M. marinum M MMAR_4790 - 1e-58 47.35% (245) enoyl-CoA hydratase
M. avium 104 MAV_0867 - 1e-63 48.82% (254) enoyl-CoA hydratase/isomerase family protein
M. smegmatis MC2 155 MSMEG_5620 - 1e-108 74.61% (256) enoyl-CoA hydratase
M. ulcerans Agy99 MUL_0359 - 1e-59 47.76% (245) enoyl-CoA hydratase
M. vanbaalenii PYR-1 Mvan_4253 - 5e-60 46.50% (243) enoyl-CoA hydratase/isomerase

CLUSTAL 2.0.9 multiple sequence alignment


TH_3045|M.thermoresistible__bu      --VKYDLPDVMTVRADGP-----IRTVTLDRAADLNSVDADLHWALANVW
MSMEG_5620|M.smegmatis_MC2_155      --MNYDVPDELSVSTDGP-----VRIVTINRETDLNSVNEKLHWALANVW
MMAR_4790|M.marinum_M               ---MYDMPTEIDVRAEGA-----LRIITLNRPDALNAVNDNLHVGLAGLW
MUL_0359|M.ulcerans_Agy99           ---MYDMPTEIDVRAEGA-----LRIITLNRPDALNAVNDNLHVGLAGLW
MAV_0867|M.avium_104                ---MYDMPTEIDVRADGA-----LRIITLNRPDSLNSVNDDLHVGLARLW
Mflv_2395|M.gilvum_PYR-GCK          ---MYGMPDEIDVTADGD-----LRIITLNRPDDLNAVNDNLHVGLAKIW
Mvan_4253|M.vanbaalenii_PYR-1       ---MYGMPEEIDVRADGA-----LRIITLNRPDDLNAVNDNLHVGLAKIW
MLBr_02402|M.leprae_Br4923          -----MKYDTILVDGYQR-----VGIITLNRPQALNALNSQMMNEITNAA
MAB_0836c|M.abscessus_ATCC_199      ----MSAARELLVERDGP-----VVILTMNRPHRRNALSTNMVSQFAAAW
Mb2698|M.bovis_AF2122/97            MPVTYDDFPSLRCEIHDQPGHEGVLELVLDSP-GLNSVGPHMHRDLADIW
Rv2679|M.tuberculosis_H37Rv         MPVTYDDFPSLRCEIHDQPGHEGVLELVLDSP-GLNSVGPHMHRDLADIW
                                              :            :  :.::     *::. .:   ::   

TH_3045|M.thermoresistible__bu      RQLAADTDARVVILTGAGRAFSAGGDLDWITSFLTDQVARDESIREGAQI
MSMEG_5620|M.smegmatis_MC2_155      RQLAADKDAKVVVLTGAGRAFSAGGDLGWITTFLDDPVARDESIREGAQI
MMAR_4790|M.marinum_M               RRLSEDRSARAAVLTGAGRAFSAGGDFAYLAELSQDADLRAKTIAHGRDI
MUL_0359|M.ulcerans_Agy99           RRLSEDRSARAAVLTGAGRAFSAGGDFAYLAELAQDADLRAKTIAHGRDI
MAV_0867|M.avium_104                QRLTDDPTARAAVITGAGRAFSAGGDFGYLKELSADADLRAKTIRDGREI
Mflv_2395|M.gilvum_PYR-GCK          EELNEDPGARAAVITGAGRAFSAGGDFHYLDELRRDEALRQKTIKHGRDL
Mvan_4253|M.vanbaalenii_PYR-1       EELNEDAGARAAVITGAGRAFSAGGDFNYLDELRNDEALRQKTIKHGRDL
MLBr_02402|M.leprae_Br4923          KELDIDPDVGAILITGSPKVFAAGADIKE--MASLTFTDAFDADFFSAWG
MAB_0836c|M.abscessus_ATCC_199      DEIDHDDGIRAAILTGAGSAYCVGGDLSDGWMVRDGSAPPLDPATIGKGL
Mb2698|M.bovis_AF2122/97            PVIDRDPAVRVVLVRGEGKAFSSGGSFDLIAETIGDYQGRLRIMREARDL
Rv2679|M.tuberculosis_H37Rv         PVIDRDPAVRVVLVRGEGKAFSSGGSFDLIAETIGDYQGRLRIMREARDL
                                      :  *    . :: *   .:. *..:                   .   

TH_3045|M.thermoresistible__bu      IEEMLRFPLPVIAAVNGPAVGLGCSVAVLCDIVLIAENAYLADPHVAVGL
MSMEG_5620|M.smegmatis_MC2_155      IEEMLRFPLPVIAAVNGPAVGLGCSVALLCDILLISEDAYLADPHVSVGL
MMAR_4790|M.marinum_M               VLGMARCRVPVVAAVNGPAVGLGCSLVALSDIVYIAPDAYLADPHVQVGL
MUL_0359|M.ulcerans_Agy99           VLGMARCRVPVVAAVNGPAVGLGCSLVALSDIVYIAPDAYLADPHVQVGL
MAV_0867|M.avium_104                VLGMARCRIPVVAAVNGPAVGLGCSLVALSDIVYIAENAYLADPHVQVGL
Mflv_2395|M.gilvum_PYR-GCK          VIGMVRCRIPVIAAVNGPAVGLGCSLAALSDVVYIAENAFFADPHVSIGL
Mvan_4253|M.vanbaalenii_PYR-1       VIGMVRCRIPVVAAVNGPAVGLGCSLAALSDVVYIAENAFFADPHVSIGL
MLBr_02402|M.leprae_Br4923          KLAAVRT--PMIAAVAGYALGGGCELAMMCDLLIAADTAKFGQPEIKLGV
MAB_0836c|M.abscessus_ATCC_199      LLSHTLTK-PLIAAVNGACLGGGCEMLQQTDIRVSDEHATFGLPEVQRGL
Mb2698|M.bovis_AF2122/97            VLNLVNFDKPVVSAIRGPAVGAGLVVALLADISVAGRAAKIIDGHTKLGV
Rv2679|M.tuberculosis_H37Rv         VLNLVNFDKPVVSAIRGPAVGAGLVVALLADISVAGRAAKIIDGHTKLGV
                                             *:::*: * .:* *  :    *:      * :   .   *:

TH_3045|M.thermoresistible__bu      VAGDGGAAMWPLLTLVLRSREYLFTGDRIPAATAVELGLASRTVPADDLL
MSMEG_5620|M.smegmatis_MC2_155      VAGDGGAALWPLLTPIMRSREFLYTGDRIDAGKAVELGLASRSVAPGQLR
MMAR_4790|M.marinum_M               VAADGGPLTWPLHISLMLAKEYALTGQRIAAQRAVELGLVN--HVAADPV
MUL_0359|M.ulcerans_Agy99           VAADGGPLTWPLHISLMLAKEYALTGQRIAAQRAVELGLAN--HVAADPV
MAV_0867|M.avium_104                VAADGGPLTWPLHISLLLAKEYALTGTRISAQRAVELGLAN--HVADDPV
Mflv_2395|M.gilvum_PYR-GCK          VAADGGPLVWGSQISLLQAKEFALTGVRIKAQKAVELGLAN--HVVDDPV
Mvan_4253|M.vanbaalenii_PYR-1       VAADGGPLVWGSQISLLQAKEFALTGVRIKAQRAVELGLAN--HVVDDPV
MLBr_02402|M.leprae_Br4923          LPGMGGSQRLTRAIGKAKAMDLILTGRTIDAAEAERSGLVSRVVLADDLL
MAB_0836c|M.abscessus_ATCC_199      VPGAGSMVRLKRQIPYTKAMEMILTGEPLTAFEAYHFGLVGHVVPAGTAL
Mb2698|M.bovis_AF2122/97            AAGDHAAICWPLLVGMAKAKYYLLTCEPLSGEEAERIGLVSICVDDDDVL
Rv2679|M.tuberculosis_H37Rv         AAGDHAAICWPLLVGMAKAKYYLLTCEPLSGEEAERIGLVSICVDDDDVL
                                     ..  .            :     *   : .  * . **..         

TH_3045|M.thermoresistible__bu      PEAIRLAERLAAQPAEALRGTKRIVNMYLSQALAGPLQAGFAAEVATMRT
MSMEG_5620|M.smegmatis_MC2_155      SEAMTLAHRLAKQPVEALQGTKRVVNMYLSQVLSGPLQAGFAAEQVSMRS
MMAR_4790|M.marinum_M               AEAVACAQRIMKLPQQAVESTKRVLNIHLERAVLASLDYALSAEHQSFTT
MUL_0359|M.ulcerans_Agy99           AEAVACAQRIVKLPQQAVESTKRVLNIHLERAVLASLDYALSAEHQSFTT
MAV_0867|M.avium_104                AEAIACAQKILELPQQAVESTKRVLNIHLERAVLASLDYALSAESQSFVT
Mflv_2395|M.gilvum_PYR-GCK          GEAIACAKKIMALPQQAVEATKRLMNIQLEKSVMASLDYANLAEYVSFGT
Mvan_4253|M.vanbaalenii_PYR-1       AEAIACAKKLIELPQQAVEATKRLMNIQLEKSVMASLDYANLAEYVSFGT
MLBr_02402|M.leprae_Br4923          PEAKAVATTISQMSRSATRMAKEAVNRSFESTLAEGLLHERRLFHSTFVT
MAB_0836c|M.abscessus_ATCC_199      DKARSLADRIVRNGPLAVRNAKEAIVRSGWLAEEDARAIEARLTRPVITS
Mb2698|M.bovis_AF2122/97            PTATRLAERLAAGAQNAIRWTKRSLN-HWYRMFGPAFETSLGLEFIGFGG
Rv2679|M.tuberculosis_H37Rv         PTATRLAERLAAGAQNAIRWTKRSLN-HWYRMFGPAFETSLGLEFIGFGG
                                      *   *  :      * . :*. :                      :  

TH_3045|M.thermoresistible__bu      AEHRDRLLALRERTR-------------
MSMEG_5620|M.smegmatis_MC2_155      DDHRARLLAFKKKAHK------------
MMAR_4790|M.marinum_M               EDFRSIVTRLTAPKN-------------
MUL_0359|M.ulcerans_Agy99           EDFRSIVTRLTAPKN-------------
MAV_0867|M.avium_104                EDFRSIVTKL-ADKN-------------
Mflv_2395|M.gilvum_PYR-GCK          ADFNRIVDGLIAKN--------------
Mvan_4253|M.vanbaalenii_PYR-1       ADFNKIVDGLIAKK--------------
MLBr_02402|M.leprae_Br4923          DDQSEGMAAFIEKRAPQFTHR-------
MAB_0836c|M.abscessus_ATCC_199      ADAREGLAAFKEKREARFTGR-------
Mb2698|M.bovis_AF2122/97            PDVREGLAAHREKRPARFGADPDPGAGS
Rv2679|M.tuberculosis_H37Rv         PDVREGLAAHREKRPARFGADPDPGAGS
                                     :    :

species	id	gene	e-value	identity (len)	annotation
M. thermoresistible (build 8)	TH_3045	-	-	100% (259)	Enoyl-CoA hydratase/isomerase
M. thermoresistible (build 8)	TH_3165	-	1e-68	50.41% (242)	PUTATIVE putative enoyl-CoA hydratase
M. thermoresistible (build 8)	TH_3065	-	6e-62	44.80% (250)	PUTATIVE enoyl-CoA hydratase