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PDEIEVRAEGDIRVITLNRPEALNAVNDSLHEGLAHLWTRLSEDYDARAAVITGAGRAFSAGGDFAYLQE LGEDPKLRAKTILHGREIVLGMTRCRVPVVAAVNGPAVGLGCSLVALSDIVYIAPQAYLADPHVQVGLVA ADGGPITWPLHISLLLAKEYALTGARIPAQRAVELGLANHLSDDPVAEAIEAAQKMAKLPRQSLEATKRL LNLHMEQAVLATLDFGNTAEEQSFRTEDFKAIVAGLNARKN*
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. smegmatis MC2 155 | MSMEG_4873 | - | - | 100% (252) | enoyl-CoA hydratase/isomerase |
| M. smegmatis MC2 155 | MSMEG_5620 | - | 1e-60 | 46.72% (244) | enoyl-CoA hydratase |
| M. smegmatis MC2 155 | MSMEG_3390 | - | 1e-25 | 33.80% (216) | enoyl-CoA hydratase |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb2698 | echA15 | 8e-27 | 33.00% (200) | enoyl-CoA hydratase |
| M. gilvum PYR-GCK | Mflv_2395 | - | 4e-96 | 68.00% (250) | enoyl-CoA hydratase/isomerase |
| M. tuberculosis H37Rv | Rv2679 | echA15 | 8e-27 | 33.00% (200) | enoyl-CoA hydratase |
| M. leprae Br4923 | MLBr_01241 | - | 1e-22 | 31.03% (232) | enoyl-CoA hydratase |
| M. abscessus ATCC 19977 | MAB_4588c | - | 1e-24 | 35.05% (214) | enoyl-CoA hydratase/isomerase |
| M. marinum M | MMAR_4790 | - | 1e-110 | 77.38% (252) | enoyl-CoA hydratase |
| M. avium 104 | MAV_0867 | - | 1e-106 | 76.19% (252) | enoyl-CoA hydratase/isomerase family protein |
| M. thermoresistible (build 8) | TH_2529 | - | 1e-126 | 86.90% (252) | PUTATIVE enoyl-CoA hydratase/isomerase |
| M. ulcerans Agy99 | MUL_0359 | - | 1e-111 | 77.78% (252) | enoyl-CoA hydratase |
| M. vanbaalenii PYR-1 | Mvan_4253 | - | 2e-97 | 68.92% (251) | enoyl-CoA hydratase/isomerase |
CLUSTAL 2.0.9 multiple sequence alignment
MSMEG_4873|M.smegmatis_MC2_155 ----------MPDEIEVR----------AEGDIRVITLNRPEALNAVNDS
TH_2529|M.thermoresistible__bu -------MYDMPPEIDVR----------ADGDIRIITLNRPDALNAVNDP
MMAR_4790|M.marinum_M -------MYDMPTEIDVR----------AEGALRIITLNRPDALNAVNDN
MUL_0359|M.ulcerans_Agy99 -------MYDMPTEIDVR----------AEGALRIITLNRPDALNAVNDN
MAV_0867|M.avium_104 -------MYDMPTEIDVR----------ADGALRIITLNRPDSLNSVNDD
Mflv_2395|M.gilvum_PYR-GCK -------MYGMPDEIDVT----------ADGDLRIITLNRPDDLNAVNDN
Mvan_4253|M.vanbaalenii_PYR-1 -------MYGMPEEIDVR----------ADGALRIITLNRPDDLNAVNDN
MAB_4588c|M.abscessus_ATCC_199 ----------MADEVLIE----------QRDRVLLITINRPDARNAVNRA
Mb2698|M.bovis_AF2122/97 MPVTYDDFPSLRCEIHDQ----------PGHEGVLELVLDSPGLNSVGPH
Rv2679|M.tuberculosis_H37Rv MPVTYDDFPSLRCEIHDQ----------PGHEGVLELVLDSPGLNSVGPH
MLBr_01241|M.leprae_Br4923 --MSQTDASCTIAELPYRSVTDLVVLDFPRPEVALITLNRPGRMNSMALD
*: : : . *::
MSMEG_4873|M.smegmatis_MC2_155 LHEGLAHLWTRLSEDYDARAAVITGAGRAFSAGGDFAYLQELGEDP----
TH_2529|M.thermoresistible__bu LHEGLAKLWDRLSEDYDARAAVLTGAGRAFSAGGDYAYLAELGEDP----
MMAR_4790|M.marinum_M LHVGLAGLWRRLSEDRSARAAVLTGAGRAFSAGGDFAYLAELSQDA----
MUL_0359|M.ulcerans_Agy99 LHVGLAGLWRRLSEDRSARAAVLTGAGRAFSAGGDFAYLAELAQDA----
MAV_0867|M.avium_104 LHVGLARLWQRLTDDPTARAAVITGAGRAFSAGGDFGYLKELSADA----
Mflv_2395|M.gilvum_PYR-GCK LHVGLAKIWEELNEDPGARAAVITGAGRAFSAGGDFHYLDELRRDE----
Mvan_4253|M.vanbaalenii_PYR-1 LHVGLAKIWEELNEDAGARAAVITGAGRAFSAGGDFNYLDELRNDE----
MAB_4588c|M.abscessus_ATCC_199 VSQGLAAAADQLDSSADLSVAIITGAGGNFCAG--------MDLKA----
Mb2698|M.bovis_AF2122/97 MHRDLADIWPVIDRDPAVRVVLVRGEGKAFSSGGSFDLIAETIGDY----
Rv2679|M.tuberculosis_H37Rv MHRDLADIWPVIDRDPAVRVVLVRGEGKAFSSGGSFDLIAETIGDY----
MLBr_01241|M.leprae_Br4923 LMKSLKQVLKRITYDHSVRVVVLTGAGRGFCSGADQKFTAPVPQVEGLTQ
: .* : . ..:: * * *.:*
MSMEG_4873|M.smegmatis_MC2_155 -KLRAKTILHGREIVLGMTRCRVPVVAAVNGPAVGLGCSLVALSDIVYIA
TH_2529|M.thermoresistible__bu -RLRAKTLQHGREIVLGMTRCRVPVVAAVNGPAVGLGCSLVALSDIVYIA
MMAR_4790|M.marinum_M -DLRAKTIAHGRDIVLGMARCRVPVVAAVNGPAVGLGCSLVALSDIVYIA
MUL_0359|M.ulcerans_Agy99 -DLRAKTIAHGRDIVLGMARCRVPVVAAVNGPAVGLGCSLVALSDIVYIA
MAV_0867|M.avium_104 -DLRAKTIRDGREIVLGMARCRIPVVAAVNGPAVGLGCSLVALSDIVYIA
Mflv_2395|M.gilvum_PYR-GCK -ALRQKTIKHGRDLVIGMVRCRIPVIAAVNGPAVGLGCSLAALSDVVYIA
Mvan_4253|M.vanbaalenii_PYR-1 -ALRQKTIKHGRDLVIGMVRCRIPVVAAVNGPAVGLGCSLAALSDVVYIA
MAB_4588c|M.abscessus_ATCC_199 -FVSGEAVLSERGLGFTNVPPRKPIIAAVEGFALAGGTELVLSCDLVVAG
Mb2698|M.bovis_AF2122/97 -QGRLRIMREARDLVLNLVNFDKPVVSAIRGPAVGAGLVVALLADISVAG
Rv2679|M.tuberculosis_H37Rv -QGRLRIMREARDLVLNLVNFDKPVVSAIRGPAVGAGLVVALLADISVAG
MLBr_01241|M.leprae_Br4923 PVRALRAMELLEEVILALRRLHQPVIAAINGPAIGGGLCLALAADVRVAS
. : . : : *:::*:.* *:. * :. .*: .
MSMEG_4873|M.smegmatis_MC2_155 PQAYLADPHVQVGLVAADGGP-ITWPLHISLLLAKEYALTGARIPAQRAV
TH_2529|M.thermoresistible__bu PDAYLADPHVQVGLVAADGGP-ITWPLHISLLLAKEYALTGARIPAQRAV
MMAR_4790|M.marinum_M PDAYLADPHVQVGLVAADGGP-LTWPLHISLMLAKEYALTGQRIAAQRAV
MUL_0359|M.ulcerans_Agy99 PDAYLADPHVQVGLVAADGGP-LTWPLHISLMLAKEYALTGQRIAAQRAV
MAV_0867|M.avium_104 ENAYLADPHVQVGLVAADGGP-LTWPLHISLLLAKEYALTGTRISAQRAV
Mflv_2395|M.gilvum_PYR-GCK ENAFFADPHVSIGLVAADGGP-LVWGSQISLLQAKEFALTGVRIKAQKAV
Mvan_4253|M.vanbaalenii_PYR-1 ENAFFADPHVSIGLVAADGGP-LVWGSQISLLQAKEFALTGVRIKAQRAV
MAB_4588c|M.abscessus_ATCC_199 RSAKFGIPEVKRGLVAGAGGL-LRLPNRIPYQVAMELALTGESFTAEDAA
Mb2698|M.bovis_AF2122/97 RAAKIIDGHTKLGVAAGDHAA-ICWPLLVGMAKAKYYLLTCEPLSGEEAE
Rv2679|M.tuberculosis_H37Rv RAAKIIDGHTKLGVAAGDHAA-ICWPLLVGMAKAKYYLLTCEPLSGEEAE
MLBr_01241|M.leprae_Br4923 TRAYFRAAGINNGLSASELGLSYLLPRAVGSSRAFEIMLSGRDVGAEEAE
* : . *: *. . : * *: . .: *
MSMEG_4873|M.smegmatis_MC2_155 ELGLANHLSDD--PVAEAIEAAQKMAKLPRQSLEATKRLLNLHMEQAVLA
TH_2529|M.thermoresistible__bu ELGLANHLSED--PVADAVAAARKMSRMPRQALEATKRLLNIHMERAVMA
MMAR_4790|M.marinum_M ELGLVNHVAAD--PVAEAVACAQRIMKLPQQAVESTKRVLNIHLERAVLA
MUL_0359|M.ulcerans_Agy99 ELGLANHVAAD--PVAEAVACAQRIVKLPQQAVESTKRVLNIHLERAVLA
MAV_0867|M.avium_104 ELGLANHVADD--PVAEAIACAQKILELPQQAVESTKRVLNIHLERAVLA
Mflv_2395|M.gilvum_PYR-GCK ELGLANHVVDD--PVGEAIACAKKIMALPQQAVEATKRLMNIQLEKSVMA
Mvan_4253|M.vanbaalenii_PYR-1 ELGLANHVVDD--PVAEAIACAKKLIELPQQAVEATKRLMNIQLEKSVMA
MAB_4588c|M.abscessus_ATCC_199 KYGFINRLVDDGQALDTALELAAKITANGPLAVAATKRIIIESASWAPEE
Mb2698|M.bovis_AF2122/97 RIGLVSICVDDDDVLPTATRLAERLAAGAQNAIRWTKRSLN-HWYRMFGP
Rv2679|M.tuberculosis_H37Rv RIGLVSICVDDDDVLPTATRLAERLAAGAQNAIRWTKRSLN-HWYRMFGP
MLBr_01241|M.leprae_Br4923 QIGLVSYRVSDDRLLDTCYSIAARMATFSRSGTELTKRALWGGLDAASLD
. *: . * : . * :: . *** :
MSMEG_4873|M.smegmatis_MC2_155 TLDFG--NTAEEQSFRTEDFKAIVAGLNARKN--------------
TH_2529|M.thermoresistible__bu TLDYG--NTAEAQSFETEDFRNIVAGLNARRN--------------
MMAR_4790|M.marinum_M SLDYA--LSAEHQSFTTEDFRSIVTRLTAPKN--------------
MUL_0359|M.ulcerans_Agy99 SLDYA--LSAEHQSFTTEDFRSIVTRLTAPKN--------------
MAV_0867|M.avium_104 SLDYA--LSAESQSFVTEDFRSIVTKL-ADKN--------------
Mflv_2395|M.gilvum_PYR-GCK SLDYA--NLAEYVSFGTADFNRIVDGLIAKN---------------
Mvan_4253|M.vanbaalenii_PYR-1 SLDYA--NLAEYVSFGTADFNKIVDGLIAKK---------------
MAB_4588c|M.abscessus_ATCC_199 AFAKQ--GEILMPIFVSEDAKEGAKAFAEKRAPVWQGK--------
Mb2698|M.bovis_AF2122/97 AFETS--LGLEFIGFGGPDVREGLAAHREKRPARFGADPDPGAGS-
Rv2679|M.tuberculosis_H37Rv AFETS--LGLEFIGFGGPDVREGLAAHREKRPARFGADPDPGAGS-
MLBr_01241|M.leprae_Br4923 KHMQSESLAQLFIALHTSNFEEAAAPCTEKRPTVLVDARGCATSPG
: : . .