For questions or suggestions e-mail us at: ioerger@cs.tamu.edu
aa seq not available
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. thermoresistible (build 8) | TH_2527 | - | - | 100% (490) | virulence factor mce family protein |
| M. thermoresistible (build 8) | TH_4161 | - | e-175 | 61.48% (501) | PUTATIVE virulence factor mce family protein |
| M. thermoresistible (build 8) | TH_2459 | - | e-162 | 56.11% (483) | PUTATIVE mce-family protein mce1f |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb0610 | mce2F | 2e-85 | 35.91% (504) | MCE-family protein MCE2F |
| M. gilvum PYR-GCK | Mflv_4533 | - | 1e-168 | 58.33% (504) | virulence factor Mce family protein |
| M. tuberculosis H37Rv | Rv1971 | mce3F | 7e-88 | 43.10% (420) | MCE-family protein MCE3F |
| M. leprae Br4923 | MLBr_02594 | mce1F | 3e-80 | 35.86% (502) | putative secreted protein |
| M. abscessus ATCC 19977 | MAB_4148c | - | 2e-84 | 35.55% (467) | MCE-family protein |
| M. marinum M | MMAR_4705 | - | 1e-160 | 53.48% (531) | MCE-family protein |
| M. avium 104 | MAV_0953 | - | 1e-162 | 59.57% (470) | mce-family protein mce1f |
| M. smegmatis MC2 155 | MSMEG_2860 | - | 1e-173 | 60.20% (495) | virulence factor mce family protein |
| M. ulcerans Agy99 | MUL_3923 | mce3F_1 | 3e-95 | 40.29% (479) | MCE-family protein Mce3F_1 |
| M. vanbaalenii PYR-1 | Mvan_4145 | - | 1e-161 | 52.78% (540) | virulence factor Mce family protein |
CLUSTAL 2.0.9 multiple sequence alignment
MMAR_4705|M.marinum_M --MLTRFVRIQLAIFAIVGMVGVAVMAVWYIQAPTLLG-IGKMTVTLELP
MAV_0953|M.avium_104 --MLTRFVRIQLAIFLIAGTIGVISMVLFYIQAPTLLG-IGRMTVTLELP
Mflv_4533|M.gilvum_PYR-GCK --MLTRFVRTQLIIFSIAAVVGLGSMVFVYLQAPVMLG-IGRMTVTLKLP
MSMEG_2860|M.smegmatis_MC2_155 --MITRFIRTQLIIFTITSVVASAMMVFSYLQAPVLFG-IGRITVTLELP
TH_2527|M.thermoresistible__bu --MLTRFVRTQLVIFVISSIIGMAVMGLVYMQIPTLLG-IGRITVQVELP
Mvan_4145|M.vanbaalenii_PYR-1 --MLTRFVRNQLIIFTIASIVGVAVMLFAYMQVPTLLG-VGRLVVTLELP
MAB_4148c|M.abscessus_ATCC_199 ---MERLIKIQLAIFAAVTVISVALMAIFYLRVPTALG-IGKHDVKAQFV
Rv1971|M.tuberculosis_H37Rv MLHLPRRVIVQLAVFTVIAVGVLAITFLHFVRLPAMLFGVGRYTVTMELV
MUL_3923|M.ulcerans_Agy99 -MRLTRQIFIQMAIFAIVATTALLIMVFGYMRVPAMVG-IGQYRVTVELP
Mb0610|M.bovis_AF2122/97 --MLTRAIKTQLVLLTVLAVIAVVVLGWYFLRIPSLVG-IGRYTLYAELP
MLBr_02594|M.leprae_Br4923 --MLTPLIRRQLVLFAILTVISLTVLGVYYLQIPSLVG-IGRYSLKAELS
: : *: :: ::: * . :*: : ::
MMAR_4705|M.marinum_M ATGGLYRFSNVTYRGVQIGKVTALGLTSSGAKATLALDASPKIPADLKAE
MAV_0953|M.avium_104 ATGGLYRFSNVTYRGVQLGKVTAVGLTPSGVKATLSLSTSPKVPADLTAE
Mflv_4533|M.gilvum_PYR-GCK NTGGLYEFSNVTYRGIEVGKVTGIEPTGDGVTVTMSLKSSPKIPTDLKAH
MSMEG_2860|M.smegmatis_MC2_155 STGGLYRFSNVTYRGIEVGKVTDVRPTRSGALATLSLQTSPRIPADLQAD
TH_2527|M.thermoresistible__bu DTGGLYRFGNVTMRGVKVGKVTGVGLRPTSAVATLSLESSARIPADLTAE
Mvan_4145|M.vanbaalenii_PYR-1 ESGGLYRFSNVTYRGVQVGKVTGVSLTENGAEATLSLETSPKIPADLQAE
MAB_4148c|M.abscessus_ATCC_199 ASGGLYQNANVTFRGVQIGRVTDVELTPEGVTATMRLNDNVKVPGNVVAA
Rv1971|M.tuberculosis_H37Rv EAGGLYRTGNVTYRGFEVGRVAAVRLTDTGVQAVLALKSGIDIPSDLKAE
MUL_3923|M.ulcerans_Agy99 EAGGLYPRSNVTYRGVEVGTVKSVHLTNTGVAAVLSLNSDVKIPADVEAE
Mb0610|M.bovis_AF2122/97 RSGGLYRTANVTYRGITIGKVTGVEPTERGARATMSIDNGYQIPTDASAN
MLBr_02594|M.leprae_Br4923 ATGGLYPTANVTYRGIAIGKVTDVEPTATGAEATMSIDSRYKIPIDSAAN
:**** .*** **. :* * : .. ..: :. :* : *
MMAR_4705|M.marinum_M VRSISAVGEYYVDLRPR-TDSPPYLHDGSVIARDRAVIGQPIGPVLDQTS
MAV_0953|M.avium_104 VLSVSAVGEQYVDLRPR-TNSPPYLHDGSVIAMRDTKIPQPVGPMLDQVN
Mflv_4533|M.gilvum_PYR-GCK VRSVSAVGEQYVDLEPR-SDAGPYLQDGSVITGDRSSIPQAVGPMLDQMS
MSMEG_2860|M.smegmatis_MC2_155 VRSVSAVGEQYVDLRPR-TDDAPYLQDGSVITAANTSVPQKVGPMLDQMS
TH_2527|M.thermoresistible__bu VRSISAVGEQYIDLLPR-RDGPPYLRDGSVIPAADVRLPQQVGPMLDQVS
Mvan_4145|M.vanbaalenii_PYR-1 VLSVSAVGEQYVDLRPN-TDEGPYLEDGARIPVANTTVPQQVGPMLDQLS
MAB_4148c|M.abscessus_ATCC_199 VKSVSAIGEQYVDLIPPPTGAAGTLRSGDVIGADRTSIPTDVSTLLRQAD
Rv1971|M.tuberculosis_H37Rv VHSHTAIGETYVELLPR-NAASPPLKNGDVIALADTSVPPDINDLLSAAN
MUL_3923|M.ulcerans_Agy99 VHSVSSVGEQYVQLLPR-SGQGPSLKDGDVIPSSRTRVPTDINTILDETN
Mb0610|M.bovis_AF2122/97 VHSVSAVGEQFVDLVST-RTSGPYLRHGQTIT--TTTVPSQIGPALDAAN
MLBr_02594|M.leprae_Br4923 VHSVSAVGEQYLDLVSS-GNPGKYLAPGQTIT--KSKIPIEIGPALDSVN
* * :::** :::* . * * * : :. * .
MMAR_4705|M.marinum_M ALINSIPKGKLSTLLDESFNAFNGAGYDFGSLFDSSAQLSGDLNGIADRT
MAV_0953|M.avium_104 ALVQSIPKTKLGQLLDESFQGFNGSGYDLGSLIDSSQTLSRDANGVVDRT
Mflv_4533|M.gilvum_PYR-GCK ALVDSIPTGTLSGLLDESYAALNGSGYELGSLFDSSARLAADADSTGDRM
MSMEG_2860|M.smegmatis_MC2_155 ALVDSIPSGQLGGLLDESFRALNGSGHELGALFDSSARLASDLDATADTT
TH_2527|M.thermoresistible__bu ALLDTIPRDQLQRLIDESYTGLSGAGYELGSLFDSSARVSADIGAVSERL
Mvan_4145|M.vanbaalenii_PYR-1 ALVGSLPKDRIPDLLDETFKAFNGAGPDFGSMLDSAATLTNDVNGVSDQM
MAB_4148c|M.abscessus_ATCC_199 GLVNTVADTRLREVLAEAFKAFNGSGQELSRLIDSSRLLIQEANTNYDST
Rv1971|M.tuberculosis_H37Rv TALEAIPHENLQTVIDESYTAVAGLGLELSRLIKGSAELAIDARANLDPL
MUL_3923|M.ulcerans_Agy99 RGLQAIPRENLKTVVDEAAVAVGGLGPELRRLITGSSKLAIDARANLDEL
Mb0610|M.bovis_AF2122/97 RGLAVLPKDRVASVLHEASEAVGGLGSSLNRLIEATQAIAHDVRGSLEDI
MLBr_02594|M.leprae_Br4923 RGLAALPKEKIGSLLDETAQAVGGLGPALQRLVSSTQAIVDAFKTNITDV
: :. : :: *: .. * * : :. .: :
MMAR_4705|M.marinum_M RTLTEDSGPFLDAQAQTTDSIRLWARSLAGVSGQLATNDPQIRTLLERGP
MAV_0953|M.avium_104 RALTEDTGPLLDTQAQTTDSIRTWARSFAGISDVMVNNDSHFRTILEKGP
Mflv_4533|M.gilvum_PYR-GCK RNLITDSEPLLDGQAQKADAITTWARSLAGITRQIADDDQAVRTILQTGP
MSMEG_2860|M.smegmatis_MC2_155 RTLIDDSRPLLDGQAASVDAIRTWARSLAGITRQVADDDAQIRTIVQTGS
TH_2527|M.thermoresistible__bu RDLVDGAAPLTDSQVQTTEALRTLARSSAGITGQVRRNDPDVRRLLADGP
Mvan_4145|M.vanbaalenii_PYR-1 RSLIDDSGPLIDSQAETADAIRTWAQSLNGISAQVVQNDPQVRALLQQGP
MAB_4148c|M.abscessus_ATCC_199 TKLIDQVGPLLDAQIRSGDNIRGSVSSLAALTEHFAKADPQLRQFLKVAP
Rv1971|M.tuberculosis_H37Rv VALIDRAGPVLDSQTHTSDAIAAWAAQLAAVTGQLQTHDSAVGDLIDRGG
MUL_3923|M.ulcerans_Agy99 TLLIDQSKPVLDTQTDTAGAIRSWASNLASITDQLQRQDSSLAGLLDQGP
Mb0610|M.bovis_AF2122/97 DDIIERSAPIIDSQVNSGNEIARWAANLNTLAAQTAQTDPAVRSILANAA
MLBr_02594|M.leprae_Br4923 NDIIQNSGPILDSQVKSDNAIERWVHNLNVLAAQSARQDQHLKSILSQAA
: *. * * . : . . :: * . :: .
MMAR_4705|M.marinum_M GAFNEASRLLDQIKPTLPVLLANLTTVGQIAVTYHASVEQILVLLPPFTA
MAV_0953|M.avium_104 ETANEASRLLDQIKPTLPVLLANLTTIGQIGITYHPSLEQLLVLLPSAVA
Mflv_4533|M.gilvum_PYR-GCK GAADEASRLLTDVKPTLPVLLANLTTVGQVGVAYHPSLEQLLVLLPPYLA
MSMEG_2860|M.smegmatis_MC2_155 GAADEASRLLDQVKPTLPVLLANLVTVGQIGVTYNPSIEQLLVLLPPYLA
TH_2527|M.thermoresistible__bu GLTTEVSALLAQVKPTLPVLLANLVSVGQVGVTYRNNIRQLMVMLPLTAS
Mvan_4145|M.vanbaalenii_PYR-1 AFAQEVSALLNQVKPTLPILLANLSTVGQTLLTYNPAIEQLLVLFPGIIA
MAB_4148c|M.abscessus_ATCC_199 GASEQASQLFAGIRPSFPVLAASLANLGRVGVIYNKSIEQSLVILPALFS
Rv1971|M.tuberculosis_H37Rv PALGETRQLLERLQPTVPILLANLVSVGQVALTYHNDIEQLLVVFPMAIA
MUL_3923|M.ulcerans_Agy99 GAADEVRALFNRLRPTLPIVLANLVSVGEVAVAYHPSLEQLLVLFPQGTA
Mb0610|M.bovis_AF2122/97 PTADQVNATFSDVRESLPQTLANLEVVIDMLKRYHNGVEQALVFLPQSGA
MLBr_02594|M.leprae_Br4923 PTADEVNTVFSDVRDSLPQTLANFEILIDMLKRYHHGVEQMLVFLPQGAS
:. : :: :.* *.: : *. :.* :*.:* :
MMAR_4705|M.marinum_M AIQSF-LGTKSPVG---LATGAFNLIISDPPACTVGFLPPSQWRNPADTT
MAV_0953|M.avium_104 IEQAA-AAPNHPEG---TAQGDFALTIDDPPICTVGFMPPNTWRSPDDLS
Mflv_4533|M.gilvum_PYR-GCK ATQSYGSSLNNPTG---MALSEFSLTLGDPPACSVGFLPPSSWRSPADLT
MSMEG_2860|M.smegmatis_MC2_155 ATQSYGSSLNNPTG---MALSEFSLTLGDPPACTVGFLPPSEWRSPADLT
TH_2527|M.thermoresistible__bu GIQSYAAPNNNPTG---IPLSEFAIGIADPPVCTVGFLPPSEWRSPDDTS
Mvan_4145|M.vanbaalenii_PYR-1 AQQSFGLPQNSPTG---LPMGDFALTISDPNPCTVGFLPSTQWRSPEDET
MAB_4148c|M.abscessus_ATCC_199 ALLTVAGGAPMDEG---AKL-DFRLNLGDPPPCLTGFVPPPLMRTPADET
Rv1971|M.tuberculosis_H37Rv AEQAGILANLNTKQAYRGQYLSFNLNLNLPPPCTTGFLPAQQRRIPTFED
MUL_3923|M.ulcerans_Agy99 VTQAVGVAKRNTIQDYKGDYLVFNLNLNLPPPCTTGFLPAQQQRVPTFED
Mb0610|M.bovis_AF2122/97 IAQSVTTEFPGQAG-----LGVGGLALNQPPPCLTGFLPASEWRSPADTS
MLBr_02594|M.leprae_Br4923 IAQTASATFPNMAA-----LDLA-LSINQPPPCLTGFIPAAEWRSPADTS
: : : * * .**:*. * *
MMAR_4705|M.marinum_M IVDTPDG-LYCKLPQDS-PIGVRGARNYPCMGQPGKRAPTVEICESDQPF
MAV_0953|M.avium_104 DIDTPDG-LYCKLPQDS-PLSVRGARNYPCMGHPGKRAPTVEICNSDQPF
Mflv_4533|M.gilvum_PYR-GCK DVDTPDG-LYCKLPQDS-PIGVRGTRNFPCMEQPGKRAPTVEICQSDRPF
MSMEG_2860|M.smegmatis_MC2_155 DVDTPDG-LYCKLPQDS-PIGVRGARNFPCMGQPGKRAPTVEICESDRPF
TH_2527|M.thermoresistible__bu EIDTPEG-LYCKLPQDS-PISVRGVRNSPCVEHPGKRAPTVEICNSDRPF
Mvan_4145|M.vanbaalenii_PYR-1 TIDTPDG-LYCKLPQDS-PMNVRGARNYPCIEHPGKRAPTVELCNDPRGF
MAB_4148c|M.abscessus_ATCC_199 LRELPRD-MYCKTAQND-PSAVRGARNYPCQEFPGKRAPTIQLCRDPRGY
Rv1971|M.tuberculosis_H37Rv YPDRPAGDLYCRVPQDS-PFNVRGARNIPCETVPGKRAPTVKLCESDAPY
MUL_3923|M.ulcerans_Agy99 YPNRAPGDLYCRVPQDA-PFNVRGARNLPCVTVPGKRAPTAKLCESNEVY
Mb0610|M.bovis_AF2122/97 TAPLPKG-TYCRIPMDA-SNVVRGARNNPCVDVPGKRAATPRECRSNEAY
MLBr_02594|M.leprae_Br4923 LQPLPVG-TYCKIPMDTPANSVRGSRNIPCVDVPGKRAASPRECRDSKPY
. . **: . : . *** ** ** *****.: . *.. :
MMAR_4705|M.marinum_M EPLAMRQHIFGTYPLDPNLI---------AQG--IPPDDRANWNRERIFG
MAV_0953|M.avium_104 MPLAMKQHVLGPYPLDPNLL---------AQG--VPPDDRVTVN-DRIFG
Mflv_4533|M.gilvum_PYR-GCK EPLAMRQHVTGPYPIDPALI---------AQG--VPPDDRVTLD-EQIYG
MSMEG_2860|M.smegmatis_MC2_155 EPLAMRQHVTGPYPIDPNLI---------AQG--VPPDDRVTLD-EHIYG
TH_2527|M.thermoresistible__bu VPLAMRQHALGPYPFDPNLI---------AQG--IPVDSRVTDE-DHLYG
Mvan_4145|M.vanbaalenii_PYR-1 VPTAIRNHITGPYPFDPNLV---------SQG--VPIDSTVEGP-DRIYL
MAB_4148c|M.abscessus_ATCC_199 VPIGSNPWRGPPAPYDTPVE---------DPRNILPPNKFPNIP--PGAE
Rv1971|M.tuberculosis_H37Rv LPLNDGYNWKG----DPNAT---------VPG------------------
MUL_3923|M.ulcerans_Agy99 VPLNDGYNWKG----DPNST---------LSGQPIPQL------------
Mb0610|M.bovis_AF2122/97 VPGGTNPWYGDPNQMLSCPAPAARCDQPVKPGQVIPAPSVNNGINPLPAD
MLBr_02594|M.leprae_Br4923 VPLGTNPWFGDPNQLLTCPAPGARCDQPVKPGLVIPAPTVDNGLNPAPAD
* .
MMAR_4705|M.marinum_M PVEGTPLPPGVGP------PEETVMPPGPLG---PPSPMG----------
MAV_0953|M.avium_104 PVEGTPLPPGAVPRGAPAGPRGENPPPGSVGAAVPPVPSSGPPALAPMSR
Mflv_4533|M.gilvum_PYR-GCK PLEGTPMPA-----------------------------------------
MSMEG_2860|M.smegmatis_MC2_155 PVEGTPVDG-----------------------------------------
TH_2527|M.thermoresistible__bu PIGGTPMPAG----------------------------------------
Mvan_4145|M.vanbaalenii_PYR-1 PPEGTPLPPGAVRAG-TPPVSEPGTPPFPVGAPAPMVPGAP---------
MAB_4148c|M.abscessus_ATCC_199 PDPGTPTLPPPSP-------------------------------------
Rv1971|M.tuberculosis_H37Rv --------------------------------------------------
MUL_3923|M.ulcerans_Agy99 --------------------------------------------------
Mb0610|M.bovis_AF2122/97 QLPGTPPPVNDPLQR-----------------------------------
MLBr_02594|M.leprae_Br4923 RLPGTPPPVSDPLSQ-----------------------------------
MMAR_4705|M.marinum_M ---EVSPIAPIDVPS-------TPPPAPSG-------APSAAPSGLGR-A
MAV_0953|M.avium_104 MSADLPPIAPLDVPTPTELPPPPPPPAPAAPDQVDGAAPQAAPSAFAG-K
Mflv_4533|M.gilvum_PYR-GCK ------------------------------------PAPGAAPASVPGPV
MSMEG_2860|M.smegmatis_MC2_155 ------------------------------------DALPVAPSAHT---
TH_2527|M.thermoresistible__bu ----------------------------------------TPPPELP---
Mvan_4145|M.vanbaalenii_PYR-1 ----PPAQPPILPPAPLLPGQGPLLPGQAVPVAPASGAVPVAPSAFGS--
MAB_4148c|M.abscessus_ATCC_199 ------------------------------------PAPEVPPAGGDVMP
Rv1971|M.tuberculosis_H37Rv --------------------------------------------------
MUL_3923|M.ulcerans_Agy99 --------------------------------------PPEPPLEQSAPP
Mb0610|M.bovis_AF2122/97 -----------------------------------PGSGTVQCNGQQPNP
MLBr_02594|M.leprae_Br4923 -----------------------------------PRSGSVQCNGQQPNT
MMAR_4705|M.marinum_M AARPGPSVAFAQYDPHTGSYVAPDGQVYRQTDLIIPD-TPKAPRTWKDML
MAV_0953|M.avium_104 ASKPAPSVVVAKYDPRTGRYVGPDGKLYQQSDLVT----PKAPKTWKDML
Mflv_4533|M.gilvum_PYR-GCK PAAGGPPVAVATYNPETGQVATPDGEVFTQSNLAAPNPAAGEGKSWQDML
MSMEG_2860|M.smegmatis_MC2_155 -AGDGPSVAIATYDPETGRYATPDGQVHHQADLATPG-----AQNWEDLL
TH_2527|M.thermoresistible__bu ---PPPSVAVAPYNPQTGQYTAPDGSVGYQHDLVRP------ATSPDDLF
Mvan_4145|M.vanbaalenii_PYR-1 NDSGVPTVGTAQYNPQTGEYIAPDGSMNRVTNVASG----ANPKSWKDLL
MAB_4148c|M.abscessus_ATCC_199 VSAQSGPMAARAYDPKNGVFLDANNQPSVYAPALDRG---TEAETWADLM
Rv1971|M.tuberculosis_H37Rv --------------------LGS----------GQDIP-----QTWQTML
MUL_3923|M.ulcerans_Agy99 GPAPPAPIAAAEYDPATGTYMGPDGHLYTQANLGQTVPE---EQTWQTML
Mb0610|M.bovis_AF2122/97 CVYTPSTFPTTIYDVQSGKVVAPDGVVYSVEASTHAG-----ADGWKVML
MLBr_02594|M.leprae_Br4923 CVYTPSGPPSAVYSPQSGELVGPDGVAYAVENSTKTG-----DDGWKEML
. ::
MMAR_4705|M.marinum_M PT----
MAV_0953|M.avium_104 PT----
Mflv_4533|M.gilvum_PYR-GCK PR----
MSMEG_2860|M.smegmatis_MC2_155 PR----
TH_2527|M.thermoresistible__bu PR----
Mvan_4145|M.vanbaalenii_PYR-1 PM----
MAB_4148c|M.abscessus_ATCC_199 LGPKPV
Rv1971|M.tuberculosis_H37Rv LPPGS-
MUL_3923|M.ulcerans_Agy99 LPPKK-
Mb0610|M.bovis_AF2122/97 APTG--
MLBr_02594|M.leprae_Br4923 APAG--