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aa seq not available
Operon Prediction Model: Genebank
Paralogs
species | id | gene | e-value | identity (len) | annotation |
M. thermoresistible (build 8) | TH_2459 | - | - | 100% (586) | mce-family protein mce1f |
M. thermoresistible (build 8) | TH_2527 | - | e-162 | 56.11% (483) | PUTATIVE virulence factor mce family protein |
M. thermoresistible (build 8) | TH_4161 | - | e-161 | 57.55% (497) | PUTATIVE virulence factor mce family protein |
Closest Orthologs (e-value cutoff: 1e-4)
species | id | gene | e-value | identity (len) | annotation |
M. bovis AF2122 / 97 | Mb3524c | mce4F | 5e-98 | 39.04% (561) | MCE-family protein MCE4F |
M. gilvum PYR-GCK | Mflv_2513 | - | 0.0 | 57.39% (589) | virulence factor Mce family protein |
M. tuberculosis H37Rv | Rv3494c | mce4F | 2e-98 | 39.04% (561) | MCE-family protein MCE4F |
M. leprae Br4923 | MLBr_02594 | mce1F | 8e-77 | 34.31% (510) | putative secreted protein |
M. abscessus ATCC 19977 | MAB_4148c | - | 1e-100 | 41.89% (456) | MCE-family protein |
M. marinum M | MMAR_4705 | - | 0.0 | 55.31% (593) | MCE-family protein |
M. avium 104 | MAV_0953 | - | 0.0 | 55.35% (589) | mce-family protein mce1f |
M. smegmatis MC2 155 | MSMEG_4785 | - | 0.0 | 70.43% (585) | mce-family protein mce1f |
M. ulcerans Agy99 | MUL_4057 | mce4F | 2e-96 | 38.38% (581) | MCE-family protein Mce4F |
M. vanbaalenii PYR-1 | Mvan_4145 | - | 0.0 | 57.22% (589) | virulence factor Mce family protein |
CLUSTAL 2.0.9 multiple sequence alignment Mb3524c|M.bovis_AF2122/97 MIDRLAKIQLSIFAVITVITLSVMAIFYLRLPATFGIGTYGVSADFVAGG Rv3494c|M.tuberculosis_H37Rv MIDRLAKIQLSIFAVITVITLSVMAIFYLRLPATFGIGTYGVSADFVAGG MUL_4057|M.ulcerans_Agy99 MIDKLTKIQLSIFAIITVLTLTVMGIFYLRLPATFGIGTYEVSADFVAGG MAB_4148c|M.abscessus_ATCC_199 -MERLIKIQLAIFAAVTVISVALMAIFYLRVPTALGIGKHDVKAQFVASG TH_2459|M.thermoresistible__bu MLTRFIRTQLILFTIAAIVGVSVMVFAYMQVPMLLGIGRMTVKIELPEAG MSMEG_4785|M.smegmatis_MC2_155 MLTRFIRTQLIIFTIASIVGVAVMLFAYMQVPTLLGLGRITVTLQLPATG Mflv_2513|M.gilvum_PYR-GCK MLTRFVRNQLIIFTIASIVGVAVMIFSYMQVPTLLGIGRLAVTLELPASG Mvan_4145|M.vanbaalenii_PYR-1 MLTRFVRNQLIIFTIASIVGVAVMLFAYMQVPTLLGVGRLVVTLELPESG MMAR_4705|M.marinum_M MLTRFVRIQLAIFAIVGMVGVAVMAVWYIQAPTLLGIGKMTVTLELPATG MAV_0953|M.avium_104 MLTRFVRIQLAIFLIAGTIGVISMVLFYIQAPTLLGIGRMTVTLELPATG MLBr_02594|M.leprae_Br4923 MLTPLIRRQLVLFAILTVISLTVLGVYYLQIPSLVGIGRYSLKAELSATG : : : ** :* : : : . *:: * .*:* :. :: * Mb3524c|M.bovis_AF2122/97 GLYKNANVTYRGVAVGRVESVGLNPNGVTAHMRLNSGTAIPSNVTATVRS Rv3494c|M.tuberculosis_H37Rv GLYKNANVTYRGVAVGRVESVGLNPNGVTAHMRLNSGTAIPSNVTATVRS MUL_4057|M.ulcerans_Agy99 GLYKNANVTYRGVAVGRVESVGLNPNGVTAQMRLNSGTAIPSNVTATVKS MAB_4148c|M.abscessus_ATCC_199 GLYQNANVTFRGVQIGRVTDVELTPEGVTATMRLNDNVKVPGNVVAAVKS TH_2459|M.thermoresistible__bu GLYRFSNVTYRGTQVGKVQSVTLTDDGVEATMSLVGSAKIPADLRAEVRS MSMEG_4785|M.smegmatis_MC2_155 GLYQFSNVTYRGSQIGKVTAVELTETGAEATLSLDRSPKVPADLQAQVRS Mflv_2513|M.gilvum_PYR-GCK GLYRFSNVTYRGVQVGKVTEVNLTENGAEAILSLDTSPEIPADLRAEVRS Mvan_4145|M.vanbaalenii_PYR-1 GLYRFSNVTYRGVQVGKVTGVSLTENGAEATLSLETSPKIPADLQAEVLS MMAR_4705|M.marinum_M GLYRFSNVTYRGVQIGKVTALGLTSSGAKATLALDASPKIPADLKAEVRS MAV_0953|M.avium_104 GLYRFSNVTYRGVQLGKVTAVGLTPSGVKATLSLSTSPKVPADLTAEVLS MLBr_02594|M.leprae_Br4923 GLYPTANVTYRGIAIGKVTDVEPTATGAEATMSIDSRYKIPIDSAANVHS *** :***:** :*:* : . *. * : : :* : * * * Mb3524c|M.bovis_AF2122/97 VSAIGEQYIDLVPPENPSSTKLRNGFRIQRQNTRIGQDVADLLRQAETLL Rv3494c|M.tuberculosis_H37Rv VSAIGEQYIDLVPPENPSSTKLRNGFRIQRQNTRIGQDVADLLRQAETLL MUL_4057|M.ulcerans_Agy99 MSAIGEQYIDLVPPDDPSAGRLHDGSRIERNNTRIGQDVADLLHQAETLV MAB_4148c|M.abscessus_ATCC_199 VSAIGEQYVDLIPPPTGAAGTLRSGDVIGADRTSIPTDVSTLLRQADGLV TH_2459|M.thermoresistible__bu MSAVGEQYIELLPRTD-SPPYLENGSVIPRSDTSVPQAVGPMLEQLSTLV MSMEG_4785|M.smegmatis_MC2_155 MSAVGEQYVELLPRKD-SGPYLENGSVIPASETTIPQAVGPMLDQLSALV Mflv_2513|M.gilvum_PYR-GCK VSAVGEQYVELLPQTD-DGPFLEDGSRIPVSNTTIPQQVGPMLDQMSALV Mvan_4145|M.vanbaalenii_PYR-1 VSAVGEQYVDLRPNTD-EGPYLEDGARIPVANTTVPQQVGPMLDQLSALV MMAR_4705|M.marinum_M ISAVGEYYVDLRPRTD-SPPYLHDGSVIARDRAVIGQPIGPVLDQTSALI MAV_0953|M.avium_104 VSAVGEQYVDLRPRTN-SPPYLHDGSVIAMRDTKIPQPVGPMLDQVNALV MLBr_02594|M.leprae_Br4923 VSAVGEQYLDLVSSGN-PGKYLAPGQTITKS--KIPIEIGPALDSVNRGL :**:** *::* . * * * : :. * . . : Mb3524c|M.bovis_AF2122/97 GSLGDTRLRELLHEAFIATNGAGPELARLIESARLLVDEANANYPQVSQL Rv3494c|M.tuberculosis_H37Rv GSLGDTRLRELLHEAFIATNGAGPELARLIESARLLVDEANANYPQVSQL MUL_4057|M.ulcerans_Agy99 NSLGDTRLREVLHEAFVATNGSGPELARLVESARLLVDEANADYPQVSQL MAB_4148c|M.abscessus_ATCC_199 NTVADTRLREVLAEAFKAFNGSGQELSRLIDSSRLLIQEANTNYDSTTKL TH_2459|M.thermoresistible__bu NTIPKDSLSRLLDESFEAFNDTGYEFGSLLDSSATVTRDANAVADQTRLL MSMEG_4785|M.smegmatis_MC2_155 DTIPKDKLSQLLDESYDAFNGTGFDFGSLLDSASTITTDASAVSDQTRAL Mflv_2513|M.gilvum_PYR-GCK GSLPKDRIPDLLDETFKAFNGAGPEFGSLLDSATTLAADMNGISEQTRAL Mvan_4145|M.vanbaalenii_PYR-1 GSLPKDRIPDLLDETFKAFNGAGPDFGSMLDSAATLTNDVNGVSDQMRSL MMAR_4705|M.marinum_M NSIPKGKLSTLLDESFNAFNGAGYDFGSLFDSSAQLSGDLNGIADRTRTL MAV_0953|M.avium_104 QSIPKTKLGQLLDESFQGFNGSGYDLGSLIDSSQTLSRDANGVVDRTRAL MLBr_02594|M.leprae_Br4923 AALPKEKIGSLLDETAQAVGGLGPALQRLVSSTQAIVDAFKTNITDVNDI :: . : :* *: . .. * : :..*: : . : Mb3524c|M.bovis_AF2122/97 IDQAGPFLQAQIRAGGDIKSLADGLARFTWQLRAADPRLRDTLAGAPDAI Rv3494c|M.tuberculosis_H37Rv IDQAGPFLQAQIRAGGDIKSLADGLARFTWQLRAADPRLRDTLADAPDAI MUL_4057|M.ulcerans_Agy99 IDQAGPFLQAQVRAGGDIKSLADGLARFTAELRQADPGLRNTLATAPDAI MAB_4148c|M.abscessus_ATCC_199 IDQVGPLLDAQIRSGDNIRGSVSSLAALTEHFAKADPQLRQFLKVAPGAS TH_2459|M.thermoresistible__bu AEDAEPFLDAQAQTTDSIRVWAASLAGITDQLDKNDPQIRTVLREGPGFA MSMEG_4785|M.smegmatis_MC2_155 IDDSGPFLDAQAQTADSIRTWARSLAGITGTVSDDDAQIRTVLREGPGFA Mflv_2513|M.gilvum_PYR-GCK IDDSGPLLESQAETTDAIRTWARSLNGISAQVVQNDPQVRALLQQGPGFA Mvan_4145|M.vanbaalenii_PYR-1 IDDSGPLIDSQAETADAIRTWAQSLNGISAQVVQNDPQVRALLQQGPAFA MMAR_4705|M.marinum_M TEDSGPFLDAQAQTTDSIRLWARSLAGVSGQLATNDPQIRTLLERGPGAF MAV_0953|M.avium_104 TEDTGPLLDTQAQTTDSIRTWARSFAGISDVMVNNDSHFRTILEKGPETA MLBr_02594|M.leprae_Br4923 IQNSGPILDSQVKSDNAIERWVHNLNVLAAQSARQDQHLKSILSQAAPTA :: *::::* .: . *. . .: .: * .: * .. Mb3524c|M.bovis_AF2122/97 DEANTAFSGIRPSFPALAASLANLGRVGVIYHKSIEQLLVVFPALFAAII Rv3494c|M.tuberculosis_H37Rv DEANTAFSGIRPSFPALAASLANLGRVGVIYHKSIEQLLVVFPALFAAII MUL_4057|M.ulcerans_Agy99 DEANTAFSGIRPSFPALAANLANLGRVGVIYNKSIEQLLVVFPALFAAIT MAB_4148c|M.abscessus_ATCC_199 EQASQLFAGIRPSFPVLAASLANLGRVGVIYNKSIEQSLVILPALFSALL TH_2459|M.thermoresistible__bu QETAQLLEQARPTLPVLLANMTTFGKIGVSYNPSIEQLLVLVPPFVAQIQ MSMEG_4785|M.smegmatis_MC2_155 QETSRLLDGIKPTLPVLLANLTTIGQIAVTYNPSIEQLLVLLPPYVAQIQ Mflv_2513|M.gilvum_PYR-GCK QEVSSLLNQVKPTLPILLANMSTVGQTLLTYNPALEQLLVLFPGIIAAQQ Mvan_4145|M.vanbaalenii_PYR-1 QEVSALLNQVKPTLPILLANLSTVGQTLLTYNPAIEQLLVLFPGIIAAQQ MMAR_4705|M.marinum_M NEASRLLDQIKPTLPVLLANLTTVGQIAVTYHASVEQILVLLPPFTAAIQ MAV_0953|M.avium_104 NEASRLLDQIKPTLPVLLANLTTIGQIGITYHPSLEQLLVLLPSAVAIEQ MLBr_02594|M.leprae_Br4923 DEVNTVFSDVRDSLPQTLANFEILIDMLKRYHHGVEQMLVFLPQGASIAQ ::. : : ::* *.: . *: .:** **..* : Mb3524c|M.bovis_AF2122/97 TSAGGVPQDEG-AKLDFKIDLHDPPPCMTGFLPPPLVRSPADESVREIPR Rv3494c|M.tuberculosis_H37Rv TSAGGVPQDEG-AKLDFKIDLHDPPPCMTGFLPPPLVRSPADESVREIPR MUL_4057|M.ulcerans_Agy99 TAAGGVPQDEG-AKLDFKVDLNDPPPCNVGFLPPPLIRSPADETLRELPP MAB_4148c|M.abscessus_ATCC_199 TVAGGAPMDEG-AKLDFRLNLGDPPPCLTGFVPPPLMRTPADETLRELPR TH_2459|M.thermoresistible__bu TY-APTTSPNGLPNGEFSLGLGDPAACTVGFLPPSAWRSPADTTVVDTPE MSMEG_4785|M.smegmatis_MC2_155 TY-TPTNSPAGLPNGEFSLGLGDPSSCTVGFLPPSAWRSPADESDMDTPD Mflv_2513|M.gilvum_PYR-GCK SFGLPQNSPTGLPTGDFALTISDPNPCTVGFLPSSQWRAPEDETTIDTPD Mvan_4145|M.vanbaalenii_PYR-1 SFGLPQNSPTGLPMGDFALTISDPNPCTVGFLPSTQWRSPEDETTIDTPD MMAR_4705|M.marinum_M SF-LGTKSPVGLATGAFNLIISDPPACTVGFLPPSQWRNPADTTIVDTPD MAV_0953|M.avium_104 AA-AAPNHPEGTAQGDFALTIDDPPICTVGFMPPNTWRSPDDLSDIDTPD MLBr_02594|M.leprae_Br4923 TASATFP---NMAALDLALSINQPPPCLTGFIPAAEWRSPADTSLQPLPV : . . : : : :* * .**:*. * * * : * Mb3524c|M.bovis_AF2122/97 DMYCKTAQNDPS-TVRGARNYPCQEFPGKRAPTVQLCRDPRGYVPVGTNP Rv3494c|M.tuberculosis_H37Rv DMYCKTAQNDPS-TVRGARNYPCQEFPGKRAPTVQLCRDPRGYVPVGTNP MUL_4057|M.ulcerans_Agy99 DMYCKVAQNDAT-TVRGARNYPCQEFPGKRAPTIQLCRDPKGYFPVGRNP MAB_4148c|M.abscessus_ATCC_199 DMYCKTAQNDPS-AVRGARNYPCQEFPGKRAPTIQLCRDPRGYVPIGSNP TH_2459|M.thermoresistible__bu GLYCKLPQDSPV-AVRGARNYPCMEHPGKRAPTVELCNDPEGYKPVATRQ MSMEG_4785|M.smegmatis_MC2_155 NLYCKLPQDSPV-AVRGARNYPCMAHPGKRAPTVELCNDPNGYQPLAQRQ Mflv_2513|M.gilvum_PYR-GCK GLYCKLPQDSPM-NVRGARNYPCLEHPGKRAPTVELCNDPRGFVPMAIRQ Mvan_4145|M.vanbaalenii_PYR-1 GLYCKLPQDSPM-NVRGARNYPCIEHPGKRAPTVELCNDPRGFVPTAIRN MMAR_4705|M.marinum_M GLYCKLPQDSPI-GVRGARNYPCMGQPGKRAPTVEICESDQPFEPLAMRQ MAV_0953|M.avium_104 GLYCKLPQDSPL-SVRGARNYPCMGHPGKRAPTVEICNSDQPFMPLAMKQ MLBr_02594|M.leprae_Br4923 GTYCKIPMDTPANSVRGSRNIPCVDVPGKRAASPRECRDSKPYVPLGTNP . *** . : . ***:** ** *****.: . *.. . : * . . Mb3524c|M.bovis_AF2122/97 WRGPPIPYGTEVTDG------------RNILPPNKFPYIPPGADPDPGVP Rv3494c|M.tuberculosis_H37Rv WRGPPIPYGTEVTDG------------RNILPPNKFPYIPPGADPDPGVP MUL_4057|M.ulcerans_Agy99 WRGPPVPYDTPVTDG------------LNVLPPNKFPYIPPDSDPDPGTP MAB_4148c|M.abscessus_ATCC_199 WRGPPAPYDTPVEDP------------RNILPPNKFPNIPPGAEPDPGTP TH_2459|M.thermoresistible__bu HALGPYPFDPNLVSQGVPIDARARLD-DNTFGPVEGTPLPPGVTAPPPRI MSMEG_4785|M.smegmatis_MC2_155 HTLGPYPFDPNLIAQGVAPDSRVRPD-DKIFGPLQGSPLPPGVTAPPQGP Mflv_2513|M.gilvum_PYR-GCK HITGPYPFDPNLVAQGIPIDDRVSGD-ERIHAPVQGTPLPPGAQRAGTPP Mvan_4145|M.vanbaalenii_PYR-1 HITGPYPFDPNLVSQGVPIDSTVEGP-DRIYLPPEGTPLPPGAVRAGTPP MMAR_4705|M.marinum_M HIFGTYPLDPNLIAQGIPPDDRANWNRERIFGPVEGTPLPPGVGP----- MAV_0953|M.avium_104 HVLGPYPLDPNLLAQGVPPDDRVTVN-DRIFGPVEGTPLPPGAVPRGAPA MLBr_02594|M.leprae_Br4923 WFGDPNQLLTCPAPG------------ARCDQPVKPGLVIPAPTVDNGLN . . . * : : * Mb3524c|M.bovis_AF2122/97 IVGPPPPGQVAGPGPAPHQPAQPAPPPNDNGPPPPFTSWMPPGYPPEPPQ Rv3494c|M.tuberculosis_H37Rv IVGPPPPGQVAGPGPAPHQPAQPAPPPNDNGPPPPFTSWMPPGYPPEPPQ MUL_4057|M.ulcerans_Agy99 IVGPPPPGVIPGPPPAPNQPAQPAPPPNDNGPPPPFTSWMPPDYPPQAPQ MAB_4148c|M.abscessus_ATCC_199 TLPPPSP------------PAPEVPPAGGDVMP----------------- TH_2459|M.thermoresistible__bu PQAPSPPPNFAGTGPGALLPG-QPLYTEPPVSPPGPAQVTEPDIVPAPPA MSMEG_4785|M.smegmatis_MC2_155 PPAPQPPPNFAGTNPGPMLPG-QPIYVDPPVPGQPPAPIRNPEIVPLPPA Mflv_2513|M.gilvum_PYR-GCK VSEPGTPP-FPVGPPGPPAPGVAPAPSQPLFVPPAPPAVLPPGQGPLLPN Mvan_4145|M.vanbaalenii_PYR-1 VSEPGTPP-FPVGAPAPMVPG-APPPAQPPILPPAP---LLPGQGPLLPG MMAR_4705|M.marinum_M -PEETVMPPGPLG---PPSPMG-------------EVSPIAPIDVPS--- MAV_0953|M.avium_104 GPRGENPPPGSVGAAVPPVPSSGPPALAPMSRMSADLPPIAPLDVPTP-T MLBr_02594|M.leprae_Br4923 PAPADRLPGTPPPVSDPLSQPRSGSVQCNGQQP----------------- Mb3524c|M.bovis_AF2122/97 VPYPATIPPPPPPE--------------------GTGPPPGPAPGPQPQA Rv3494c|M.tuberculosis_H37Rv VPYPATIPPPPPPE--------------------GTGPPPGPAPGPQPQA MUL_4057|M.ulcerans_Agy99 IPYPKTLPPPPPPV--------------------GVGP----EPGPQPQA MAB_4148c|M.abscessus_ATCC_199 ---------------------------------------------VSAQS TH_2459|M.thermoresistible__bu QLPSATEVPVPPGVNPDDLHLPPGAVPVPGPGSGTVISPSSSSSARDG-G MSMEG_4785|M.smegmatis_MC2_155 QLPQATEVPVPHG-----LTAPP---PATDPG-APVAAPSAFDGGKSS-G Mflv_2513|M.gilvum_PYR-GCK QA-----VPAPPG-------------------GAVPAAPSAFGGNASG-G Mvan_4145|M.vanbaalenii_PYR-1 QA-----VPVAPAS------------------GAVPVAPSAFGSNDSG-V MMAR_4705|M.marinum_M -----TPPPAPSG--------------------APSAAPSGLGRAAARPG MAV_0953|M.avium_104 ELPPPPPPPAPAAP-------------DQVDGAAPQAAPSAFAGKASKPA MLBr_02594|M.leprae_Br4923 -------------------------------------------NTCVYTP Mb3524c|M.bovis_AF2122/97 SGPAYTIYDQLSGAFADPAGGTGIFAPGMTG--ASSAENWVDLMRDPRQL Rv3494c|M.tuberculosis_H37Rv SGPAYTIYDQLSGAFADPAGGTGIFAPGMTG--ASSAENWVDLMRDPRQL MUL_4057|M.ulcerans_Agy99 SGPAYTTYDPLTGVFKDPAGGAGIFVGGISG--ASSAENWVDLMLAPRTM MAB_4148c|M.abscessus_ATCC_199 GPMAARAYDPKNGVFLDANNQPSVYAPALDR--GTEAETWADLMLGPKPV TH_2459|M.thermoresistible__bu PTVAFARYNPRTGEYMASDGRLYRQSDLSS-----TPKSWQELMPT---- MSMEG_4785|M.smegmatis_MC2_155 PAVTVAKYNPRNGEYMGADGKLYRQANLVG-----NAKSWQDLMPS---- Mflv_2513|M.gilvum_PYR-GCK PSVATAAYDPNTGQYLSPDGAMHQISNVTPG---GTPKSWKDLLPM---- Mvan_4145|M.vanbaalenii_PYR-1 PTVGTAQYNPQTGEYIAPDGSMNRVTNVASG---ANPKSWKDLLPM---- MMAR_4705|M.marinum_M PSVAFAQYDPHTGSYVAPDGQVYRQTDLIIPDTPKAPRTWKDMLPT---- MAV_0953|M.avium_104 PSVVVAKYDPRTGRYVGPDGKLYQQSDLVT---PKAPKTWKDMLPT---- MLBr_02594|M.leprae_Br4923 SGPPSAVYSPQSGELVGPDGVAYAVENSTKT----GDDGWKEMLAPAG-- *. .* . . * :::