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aa seq not available
Operon Prediction Model: Genebank
Paralogs
species | id | gene | e-value | identity (len) | annotation |
M. thermoresistible (build 8) | TH_2450 | - | - | 100% (534) | putative FAD dependent oxidoreductase |
M. thermoresistible (build 8) | TH_4080 | - | 3e-64 | 35.73% (445) | PUTATIVE conserved hypothetical protein |
M. thermoresistible (build 8) | TH_3452 | - | 3e-58 | 31.01% (503) | PUTATIVE lipolytic enzyme |
Closest Orthologs (e-value cutoff: 1e-4)
species | id | gene | e-value | identity (len) | annotation |
M. bovis AF2122 / 97 | Mb1428c | - | 7e-83 | 35.13% (501) | monoxygenase |
M. gilvum PYR-GCK | Mflv_3377 | - | 1e-85 | 36.00% (500) | FAD dependent oxidoreductase |
M. tuberculosis H37Rv | Rv1393c | - | 7e-83 | 35.13% (501) | monoxygenase |
M. leprae Br4923 | MLBr_00065 | - | 4e-27 | 27.39% (449) | putative monooxygenase |
M. abscessus ATCC 19977 | MAB_0099 | - | 1e-137 | 47.86% (514) | monooxygenase |
M. marinum M | MMAR_2207 | - | 2e-82 | 34.90% (510) | monoxygenase |
M. avium 104 | MAV_3378 | - | 1e-81 | 35.26% (502) | lipolytic enzyme |
M. smegmatis MC2 155 | MSMEG_0816 | - | 1e-82 | 34.46% (502) | flavin-binding monooxygenase |
M. ulcerans Agy99 | MUL_1793 | - | 3e-78 | 34.86% (502) | monoxygenase |
M. vanbaalenii PYR-1 | Mvan_0721 | - | 1e-82 | 33.99% (506) | FAD-dependent pyridine nucleotide-disulphide oxidoreductase |
CLUSTAL 2.0.9 multiple sequence alignment TH_2450|M.thermoresistible__bu MTVTGDVRPEYDVAIIGAGPGGIAAAHKLR-RRGITDIAILERGDDFGGT MAB_0099|M.abscessus_ATCC_1997 ---MSDI--DFRVAIIGAGPGGIAAAYYLR-RQGINDFVILERADDFGGT Mb1428c|M.bovis_AF2122/97 ------MMPDYHALIVGAGFSGIGAAIKLD-RAGFSDYLVVEAGDGVGGT Rv1393c|M.tuberculosis_H37Rv ------MMPDYHALIVGAGFSGIGAAIKLD-RAGFSDYLVVEAGDGVGGT MAV_3378|M.avium_104 --MSSPAVPDHHTLIIGAGFSGIGAAIKLD-KAGLPDYRVIEAGDGVGGT MMAR_2207|M.marinum_M ----MSIEPDYQIVIVGAGFSGIGAAISLD-KAGFGDYLVIEAGDGVGGT MUL_1793|M.ulcerans_Agy99 -------------MIVGAGFSGIGAAISLD-KAGFGDYLVIEAGDAVGGT MSMEG_0816|M.smegmatis_MC2_155 -----MRPVVHDAVIVGAGFAGLGAAIQLK-KMSFDDFVILEREDDLGGT Mvan_0721|M.vanbaalenii_PYR-1 -----MISEHFDAVIVGAGFAGIGAAIQFK-RMGIENFVILEREDDLGGT Mflv_3377|M.gilvum_PYR-GCK -----MSTEQLDAVIVGAGFGGMGAAIQLD-RLGYQKIAILDREDDLGGT MLBr_00065|M.leprae_Br4923 -MVVMAETEYLDVVIVGAGISGVSAAWHLQDRCPNKSYVILEKRAGMGGT *:*** .*:.** : : . ::: .*** TH_2450|M.thermoresistible__bu WRDNHYPGLAVDIPILWYQFSFNRNPRWSRVFAPGPEIHRYLTDTARSLG MAB_0099|M.abscessus_ATCC_1997 WRDNTYPGLAVDIPVVFYQLSFARTGRWNKLFADGADIQRYHLSVVAQLG Mb1428c|M.bovis_AF2122/97 WHWNTYPGIAVDIPSFSYQFSFEQSRHWSRTYAPGHELKAYAEHCVDKYG Rv1393c|M.tuberculosis_H37Rv WHWNTYPGIAVDIPSFSYQFSFEQSRHWSRTYAPGHELKAYAEHCVDKYG MAV_3378|M.avium_104 WHWNTYPGIAVDIPSFSYQFSFEQSRHWSRTYAPGRELKAYAEHCADKYG MMAR_2207|M.marinum_M WFWNTYPGIAVDIPSFSYQFSFEQSPDWSRSYAPGRELRAYAEHCADKYG MUL_1793|M.ulcerans_Agy99 WFWNTYPGIAVDIPSFSYQFSFEQSPDWSRSYAPGRELRAYAEHCADKYG MSMEG_0816|M.smegmatis_MC2_155 WYVNHYPGLAVDVPTTTYSYFFEPNPSWSRLFSTGREIKRYADDVADKYD Mvan_0721|M.vanbaalenii_PYR-1 WYVNHYPGLAVDVPTTTYSYFFEPNPNWSRLFSTGAEIKQYADDVADKYD Mflv_3377|M.gilvum_PYR-GCK WHVNRYPGLTVDVPSTTYSYWFEPNPYWSRLYAPGTELKSYAVHVADKYD MLBr_00065|M.leprae_Br4923 WDLFRYPGIRSDSDMYTLGFRFRP-WTKCQAIADGKPILEYIKSTAVMHG * ***: * * : : * : * . . TH_2450|M.thermoresistible__bu LYPLLRPHHDVVGQRWNAENAMWQLTVRDRPP---VTARFVISSVGG-YV MAB_0099|M.abscessus_ATCC_1997 LREHFQGGSEVIAERWDDDGDYWELTITGKPV---VRARYVISAVGG-YI Mb1428c|M.bovis_AF2122/97 IRSRIRLNTKVLAAEFDDEHSLWRVQTDPGGE---ITARFLISACG--IL Rv1393c|M.tuberculosis_H37Rv IRSRIRLNTKVLAAEFDDEHSLWRVQTDPGGE---ITARFLISACG--IL MAV_3378|M.avium_104 IRSRIRFNTKVLAAEFDDEQRLWRVQTDPGGE---VTARFLISACG--VL MMAR_2207|M.marinum_M IRPRIRFNTKVLGAEFDDERSLWRLQTDPGGE---LTTRFIINASG--VL MUL_1793|M.ulcerans_Agy99 IRPRIRFNTKVLGAELDDERSLWRLQTDPGGD---LITRFIINASG--VL MSMEG_0816|M.smegmatis_MC2_155 VRRHIRFGTTVTGARWDEDDNVWQVSLTDGEQ---LQARFLITATG--FL Mvan_0721|M.vanbaalenii_PYR-1 VRRHIRFGVTVGGARWDDDAQLWRVNLADGET---VDARYLVTATG--FL Mflv_3377|M.gilvum_PYR-GCK LRRYMRFNTTVEGARWDEESRRWSVSLVGGHT---LTAQFLILATG--YL MLBr_00065|M.leprae_Br4923 IDKYIRLNHKVTGADWSSIENRWTVQVENNGTPRMISCSFLFLCSGYYNY : :: * . . * : : ::. . * TH_2450|M.thermoresistible__bu NAR-ATDLEGLSDFTGKVLRPNCWDDGYDTRDKRVAVIGTGSSGAQIVSA MAB_0099|M.abscessus_ATCC_1997 DTKPGPDIPGINDFRGKVMRPNEWDHSYDYTGKRVAVIGTGSSGIQIAPA Mb1428c|M.bovis_AF2122/97 TVPKLPDIDGVDSFEGVTMHTARWDHTQDLTGKRVGIIGTGASAVQVIPE Rv1393c|M.tuberculosis_H37Rv TVPKLPDIDGVDSFEGVTMHTARWDHTQDLTGKRVGIIGTGASAVQVIPE MAV_3378|M.avium_104 TVPNLPDIDGVDSFAGITMHTARWDHGQDLRGKRVAVIGTGASAVQVIPE MMAR_2207|M.marinum_M TVPKLPDIAGVDSFAGVTMHTARWDHSQELTGKRVGIIGTGASAVQVIPE MUL_1793|M.ulcerans_Agy99 TVPKLPDIAGVDSFAGVTMHTARWDHSQELTGKRVGIIGTGASAVQVIPE MSMEG_0816|M.smegmatis_MC2_155 SQPHTPDIPGITEFDGKVIHTTDWDDGCSLYGRRAAVVGTGATAVQLIPE Mvan_0721|M.vanbaalenii_PYR-1 SQPHMPDIPGIAEFDGRVIHTTAWDDSYDPTGEKIGIIGTGATAVQLIPE Mflv_3377|M.gilvum_PYR-GCK CQPRKPDIPGIEDFAGTVLHAQEWDDDYSLKGRRAAIIGTGSTGVQLIPK MLBr_00065|M.leprae_Br4923 EQGYAPTFLGSEDFTGPIIHPQHWPEDLDYAAKNIVVIGSGATAVTLVPA . : * .* * ::. * . . .. ::*:*::. : . TH_2450|M.thermoresistible__bu LSGR-VARLDVYQRTPNWILPRPDFALPRALQRVLELPGVAAVLHNIGRA MAB_0099|M.abscessus_ATCC_1997 VART-AASVTTFQRTPAWIIPKPNPALSPRAQRILSAP-LMLTLINASIA Mb1428c|M.bovis_AF2122/97 MAPI-VSHLTVFQRTPIWCFPKFDVPLPTAVR-WAMRIPGGKAVHRLLSQ Rv1393c|M.tuberculosis_H37Rv MAPI-VSHLTVFQRTPIWCFPKFDVPLPTAVR-WAMRIPGGKAVHRLLSQ MAV_3378|M.avium_104 IAPI-VSSLTVFQRTPIWCFPKLDVPLPAPAR-WAMRFPGGKALQRLLSQ MMAR_2207|M.marinum_M IAPI-VKHLTVFQRTPIWCFPKFDFPLPAALR-WAMRIPGGKALQRLLSQ MUL_1793|M.ulcerans_Agy99 IAPI-VKHLTVFQRTPIWCFPKFDFPLPAALR-WAMRIPGGKALQRLLSQ MSMEG_0816|M.smegmatis_MC2_155 LAER-VAELTVYQRTPIWVVPKVDVRFPPAVRALFARVPLTQRVVRAITD Mvan_0721|M.vanbaalenii_PYR-1 LAEK-AADLTVYQRTPIWVVPKIDFRFSERAKQLFARIPLTQRLIRVITD Mflv_3377|M.gilvum_PYR-GCK LADD-VAELTVYQRTPIWVMPKLDFPFGRAAQRLFAKVPATQQFLRMSSD MLBr_00065|M.leprae_Br4923 LANSGAKHVTMLQRSPTYIVSQPAKDKIAARLNRWLPDKYAYTAVRWKNI :: . : **:* : ..: . TH_2450|M.thermoresistible__bu VFDLFFVVPIVHLMAHVPDRVLVRLLRGYDSLARFAFRVLLRAVVHDPQT MAB_0099|M.abscessus_ATCC_1997 VSMDIVEFVLFHLLPLLPESVLRVLIPRYDNMARRWYRRLLRSTVQDPEL Mb1428c|M.bovis_AF2122/97 AFVEATFPIAAHYFAVFP----------LAKHMESAGRRYLRQQVHDPVV Rv1393c|M.tuberculosis_H37Rv AFVEATFPIAAHYFAVFP----------LAKHMESAGRRYLRQQVHDPVV MAV_3378|M.avium_104 AYVELTFPISAHYFTVIP----------LAKRMAALGRAYLRRQVRDPAV MMAR_2207|M.marinum_M AYVEATFPISAHYFTVFP----------LARWSAVLGRRYLRQRVNDPVV MUL_1793|M.ulcerans_Agy99 AYVEATFPISAHYFTVFP----------LARWSAVLGRRYLRQRVDDPVV MSMEG_0816|M.smegmatis_MC2_155 AIYAFMVDTAVLKHRYFR---------RLNIAAADLGRLHLAASIRDPDL Mvan_0721|M.vanbaalenii_PYR-1 TIYELMVWVAVLHNRQTRG--------RFNIAAGDLAKMHRFATIRDKEL Mflv_3377|M.gilvum_PYR-GCK AFMDVMVTIAMWKFRQFR---------PVNTAAARIGALHRFLAIRDKGL MLBr_00065|M.leprae_Br4923 LRQSALYGACQKWPQRMR-----------NILLGHVARRLPKGYDVQKHF : TH_2450|M.thermoresistible__bu RRRLMPAHGILAKRPIISGSYLPAFNDPRTHLITTPIERITAAGVRTTDG MAB_0099|M.abscessus_ATCC_1997 RKALMPSYGILARRTILSSDFLQAVDAGEVQLVIEPIARVTEDGIDTADG Mb1428c|M.bovis_AF2122/97 REQLTPRYAVGCKRPGFHNTYLSTFNRDNVRLVTEPIDKITPTAVATTDG Rv1393c|M.tuberculosis_H37Rv REQLTPRYAVGCKRPGFHNTYLSTFNRDNVRLVTEPIDKITPTAVATTDG MAV_3378|M.avium_104 REQLTPRYAVGCKRPGFHNGYLATFNRDNVRLVTEPIDKITPDAVATTDG MMAR_2207|M.marinum_M RDQLTPRYAVGCKRPGFHNGYLSTFNRDNVQLVTEPIEKITPTAVATDDG MUL_1793|M.ulcerans_Agy99 RDQLTPRYAVDCKRPGFHNGYLSTFNRDNVQLVTEPIEKITPTSVATDDG MSMEG_0816|M.smegmatis_MC2_155 RSKLTPDYDFGCKRPTFSNSYYRTFTKPHVHLQADGIDHVEPDGIVNADG Mvan_0721|M.vanbaalenii_PYR-1 RAKLTPDYDFGCKRPTFSNSYYRTFTKPHVHLQDSGIARIESDGIVGNDG Mflv_3377|M.gilvum_PYR-GCK RRKLTPDYDFGCKRPTLSNTYYRTFNKKHVHLETSGIERIEADGIVTRDG MLBr_00065|M.leprae_Br4923 GPHYNPWEQRLCLVP--DGDLFRAIRKGTVDMVTDAIDRFTSTGIRLKSG * . . . :. . : * :. .: .* TH_2450|M.thermoresistible__bu VERPVDLIVTATGYELWTDPETYFPGTILGDAGFDLALDYRENGLRSYGG MAB_0099|M.abscessus_ATCC_1997 AHHAVDLLVLATGYEIYTDPEHYKPGAVRGRNGFDLGTYYCDNDMRTYGG Mb1428c|M.bovis_AF2122/97 ASHEIDVLVLATGFKVL-DTDSIPTYAVTGTGGASLSRFWDEHRLQAYEG Rv1393c|M.tuberculosis_H37Rv ASHEIDVLVLATGFKVL-DTDSIPTYAVTGTGGASLSRFWDEHRLQAYEG MAV_3378|M.avium_104 ETHEIDVLILATGFKVM-DPDSVPTFAVTGSGGRSLSRFWDEHRLQAYEG MMAR_2207|M.marinum_M TDHEIDVLILATGFKVL-DTDDVLTYPVIGRAGRSLSQFWEEHRAQAYQG MUL_1793|M.ulcerans_Agy99 TDHEIDVLILATGFKVL-DTDDVLTYPVIGRAGRSLSQFWEEHRAQAYQG MSMEG_0816|M.smegmatis_MC2_155 SKTVIDTLVLATGFDLW-EAN-FPAIEVIGRQGRDLGKWWRETRFQAYQG Mvan_0721|M.vanbaalenii_PYR-1 TKTPIDTLVLATGFDLW-EAN-FPAIEVIGRDGRNLGKWWRETRFQAYQG Mflv_3377|M.gilvum_PYR-GCK TKKVIDTLVLATGFDVW-ESN-LPAIPVIGREGRDLGKWWRENKFQAYEG MLBr_00065|M.leprae_Br4923 NELRADIIVTATGLNLQ-----LFGGAVATVDGQPVDLAQT----MSYKG * :: *** .: : * : :* * TH_2450|M.thermoresistible__bu TAHPRLPNRWEIVGPLAFVGVGWTDFVETMAEHAVRIIDAARRRGADVVT MAB_0099|M.abscessus_ATCC_1997 SALPGLPNRWMLVGPEGNQGQGWHAMVEANARHAARIIGASSRCHREVAE Mb1428c|M.bovis_AF2122/97 VSVPGYPNFFTVFGPYGYVGSSYFALIETQAHHIIRCLKRARRTGATRIE Rv1393c|M.tuberculosis_H37Rv VSVPGYPNFFTVFGPYGYVGSSYFALIETQAHHIIRCLKRARRTGATRIE MAV_3378|M.avium_104 VTVPGFPNLFTVFGPYGYVGSSYFALIEAQTHHIVRCLKRAQRLGATRVE MMAR_2207|M.marinum_M VSVPGYPNFFAVFGPYGYVGSSYFALIETQTHHILRCLKRARRDGATRVE MUL_1793|M.ulcerans_Agy99 VSVPGYRNFFAVFGPYGYVGSSYFALIETQTHHILRCLKRARRDGATRVE MSMEG_0816|M.smegmatis_MC2_155 VSMPYFPNYLSLAGPYAFLGLNFFNTMEYQMRLMERLLGEVARRDARTFE Mvan_0721|M.vanbaalenii_PYR-1 VSMPHFPNFLSLASPFAFLGLNFFNTVEYQMRHMDRLFGELRRRGATTFE Mflv_3377|M.gilvum_PYR-GCK LTVPLFPNLLTQASPYAWVGMSWFDTVEYQMRHMKRLFGELQRRGADTFE MLBr_00065|M.leprae_Br4923 MMLSGLPNMIYTVG---YTNASWTLKADLVSEFFCRLLNYMNANDFDTVA . * . . .: : . * : TH_2450|M.thermoresistible__bu VTDEAFGRWDARMRKAGKAARLYYTRCNPGVNTYYVNSQRDTVYHRPQTI MAB_0099|M.abscessus_ATCC_1997 VSRRAFDRWVRKMAHQSKAIRLYATDCQPPLSTYFVNSKGETRYYRPQTV Mb1428c|M.bovis_AF2122/97 VTEEANARYFAEVMRRRHRQVFWQDSCRL-ANSYYFDKNGD-VPLRPTTT Rv1393c|M.tuberculosis_H37Rv VTEEANARYFAEVMRRRHRQVFWQDSCRL-ANSYYFDKNGD-VPLRPTTT MAV_3378|M.avium_104 VSEEANDRYFAEMMRRRHRQIFWQDSCRL-ANSYYFDKNGD-VPLRPGTT MMAR_2207|M.marinum_M VTEEANARYFAEMMRRRYRQVFWQDSCRR-ANSYYFDKNGD-VPLRPTTT MUL_1793|M.ulcerans_Agy99 VTEEANARYFAEMMRRRYRQVFWQDSCRR-ANSYYFDKNGD-VPLRPTTT MSMEG_0816|M.smegmatis_MC2_155 VTEEANRRYLDRMTDALGDSLFTLGNCAS-ARSYYFNPSGEATLLRPMTT Mvan_0721|M.vanbaalenii_PYR-1 ITEEANARYLARMTALLGDSLFTNGSCAT-ARSYYFNPSGEPTLLRPTST Mflv_3377|M.gilvum_PYR-GCK VTEEANAEFLDRMETLLEDSVFRLGNCAN-SRSYWFNSSGEAPLFRPQSI MLBr_00065|M.leprae_Br4923 VEYPGSDVEERPFMDFTPGYVLRSLDALPKQGSRTPWRLNQNYLRDIRLI : . . : . : : TH_2450|M.thermoresistible__bu TESLVFAHRPPLTDYRFERRPAAARSAVRALRHAEGNEAV MAB_0099|M.abscessus_ATCC_1997 SEMNWFSKHSPISDYSL--RPVSMETKVRYDQSA------ Mb1428c|M.bovis_AF2122/97 VEAYWRSRRFDLGDYRISS--------------------- Rv1393c|M.tuberculosis_H37Rv VEAYWRSRRFDLGDYRISS--------------------- MAV_3378|M.avium_104 PEVYWRSRRFDLDDYRFTG--------------------- MMAR_2207|M.marinum_M VEAYWRGRHFDLDNYRFGR--------------------- MUL_1793|M.ulcerans_Agy99 VEAYWRGRHFDLDDYRFGR--------------------- MSMEG_0816|M.smegmatis_MC2_155 RRAVAEASRFPLSDYTFA---------------------- Mvan_0721|M.vanbaalenii_PYR-1 RAAIREATDFPIDDYRIV---------------------- Mflv_3377|M.gilvum_PYR-GCK RQAVKEQETFPLSDYAIA---------------------- MLBr_00065|M.leprae_Br4923 RRGKVADEGLLFAKKTTPVTV------------------- : .