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MSDIDFRVAIIGAGPGGIAAAYYLRRQGINDFVILERADDFGGTWRDNTYPGLAVDIPVVFYQLSFARTG RWNKLFADGADIQRYHLSVVAQLGLREHFQGGSEVIAERWDDDGDYWELTITGKPVVRARYVISAVGGYI DTKPGPDIPGINDFRGKVMRPNEWDHSYDYTGKRVAVIGTGSSGIQIAPAVARTAASVTTFQRTPAWIIP KPNPALSPRAQRILSAPLMLTLINASIAVSMDIVEFVLFHLLPLLPESVLRVLIPRYDNMARRWYRRLLR STVQDPELRKALMPSYGILARRTILSSDFLQAVDAGEVQLVIEPIARVTEDGIDTADGAHHAVDLLVLAT GYEIYTDPEHYKPGAVRGRNGFDLGTYYCDNDMRTYGGSALPGLPNRWMLVGPEGNQGQGWHAMVEANAR HAARIIGASSRCHREVAEVSRRAFDRWVRKMAHQSKAIRLYATDCQPPLSTYFVNSKGETRYYRPQTVSE MNWFSKHSPISDYSLRPVSMETKVRYDQSA
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. abscessus ATCC 19977 | MAB_0099 | - | - | 100% (520) | monooxygenase |
| M. abscessus ATCC 19977 | MAB_0142c | - | e-120 | 41.28% (499) | putative monooxygenase |
| M. abscessus ATCC 19977 | MAB_4017c | - | e-107 | 40.47% (509) | monooxygenase |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb1428c | - | 2e-77 | 33.07% (505) | monoxygenase |
| M. gilvum PYR-GCK | Mflv_4607 | - | 1e-75 | 33.66% (505) | cyclohexanone monooxygenase |
| M. tuberculosis H37Rv | Rv1393c | - | 3e-77 | 33.07% (505) | monoxygenase |
| M. leprae Br4923 | MLBr_00065 | - | 1e-30 | 27.94% (408) | putative monooxygenase |
| M. marinum M | MMAR_2207 | - | 2e-74 | 31.87% (502) | monoxygenase |
| M. avium 104 | MAV_3378 | - | 2e-79 | 34.00% (503) | lipolytic enzyme |
| M. smegmatis MC2 155 | MSMEG_0816 | - | 2e-76 | 34.27% (496) | flavin-binding monooxygenase |
| M. thermoresistible (build 8) | TH_2450 | - | 1e-137 | 47.86% (514) | PUTATIVE putative FAD dependent oxidoreductase |
| M. ulcerans Agy99 | MUL_1793 | - | 9e-72 | 31.99% (497) | monoxygenase |
| M. vanbaalenii PYR-1 | Mvan_2671 | - | 4e-80 | 35.04% (508) | cyclohexanone monooxygenase |
CLUSTAL 2.0.9 multiple sequence alignment
MAB_0099|M.abscessus_ATCC_1997 ----------------MSDI--DFRVAIIGAGPGGIAAAYYLRRQGIN-D
TH_2450|M.thermoresistible__bu -------------MTVTGDVRPEYDVAIIGAGPGGIAAAHKLRRRGIT-D
Mb1428c|M.bovis_AF2122/97 -------------------MMPDYHALIVGAGFSGIGAAIKLDRAGFS-D
Rv1393c|M.tuberculosis_H37Rv -------------------MMPDYHALIVGAGFSGIGAAIKLDRAGFS-D
MMAR_2207|M.marinum_M -----------------MSIEPDYQIVIVGAGFSGIGAAISLDKAGFG-D
MUL_1793|M.ulcerans_Agy99 --------------------------MIVGAGFSGIGAAISLDKAGFG-D
MAV_3378|M.avium_104 ---------------MSSPAVPDHHTLIIGAGFSGIGAAIKLDKAGLP-D
Mvan_2671|M.vanbaalenii_PYR-1 --------------------MHDVETVIVGAGFSGIGAAIGLDRVGMS-D
Mflv_4607|M.gilvum_PYR-GCK MSVHVAGDENAPTSGAPTYEVPTHEILVIGAGFSGIGVGIKLLKEGFS-D
MSMEG_0816|M.smegmatis_MC2_155 ------------------MRPVVHDAVIVGAGFAGLGAAIQLKKMSFD-D
MLBr_00065|M.leprae_Br4923 --------------MVVMAETEYLDVVIVGAGISGVSAAWHLQDRCPNKS
::*** .*:... * .
MAB_0099|M.abscessus_ATCC_1997 FVILERADDFGGTWRDNTYPGLAVDIPVVFYQLSFARTGRWNKLFADGAD
TH_2450|M.thermoresistible__bu IAILERGDDFGGTWRDNHYPGLAVDIPILWYQFSFNRNPRWSRVFAPGPE
Mb1428c|M.bovis_AF2122/97 YLVVEAGDGVGGTWHWNTYPGIAVDIPSFSYQFSFEQSRHWSRTYAPGHE
Rv1393c|M.tuberculosis_H37Rv YLVVEAGDGVGGTWHWNTYPGIAVDIPSFSYQFSFEQSRHWSRTYAPGHE
MMAR_2207|M.marinum_M YLVIEAGDGVGGTWFWNTYPGIAVDIPSFSYQFSFEQSPDWSRSYAPGRE
MUL_1793|M.ulcerans_Agy99 YLVIEAGDAVGGTWFWNTYPGIAVDIPSFSYQFSFEQSPDWSRSYAPGRE
MAV_3378|M.avium_104 YRVIEAGDGVGGTWHWNTYPGIAVDIPSFSYQFSFEQSRHWSRTYAPGRE
Mvan_2671|M.vanbaalenii_PYR-1 YVVVEAGDEPGGTWYWNTYPGIAVDIPSFSYQFSFEQSSAWSRTYAHGHE
Mflv_4607|M.gilvum_PYR-GCK FLIVDEAQGVGGTWYWNTYPGIAVDIPSYSYQFSFEKRPSWSRTYAPGIE
MSMEG_0816|M.smegmatis_MC2_155 FVILEREDDLGGTWYVNHYPGLAVDVPTTTYSYFFEPNPSWSRLFSTGRE
MLBr_00065|M.leprae_Br4923 YVILEKRAGMGGTWDLFRYPGIRSDSDMYTLGFRFRP-WTKCQAIADGKP
::: **** ***: * * : : *
MAB_0099|M.abscessus_ATCC_1997 IQRYHLSVVAQLGLREHFQGGSEVIAERWDDDGDYWELTITGKP---VVR
TH_2450|M.thermoresistible__bu IHRYLTDTARSLGLYPLLRPHHDVVGQRWNAENAMWQLTVRDRP---PVT
Mb1428c|M.bovis_AF2122/97 LKAYAEHCVDKYGIRSRIRLNTKVLAAEFDDEHSLWRVQTDPGG---EIT
Rv1393c|M.tuberculosis_H37Rv LKAYAEHCVDKYGIRSRIRLNTKVLAAEFDDEHSLWRVQTDPGG---EIT
MMAR_2207|M.marinum_M LRAYAEHCADKYGIRPRIRFNTKVLGAEFDDERSLWRLQTDPGG---ELT
MUL_1793|M.ulcerans_Agy99 LRAYAEHCADKYGIRPRIRFNTKVLGAELDDERSLWRLQTDPGG---DLI
MAV_3378|M.avium_104 LKAYAEHCADKYGIRSRIRFNTKVLAAEFDDEQRLWRVQTDPGG---EVT
Mvan_2671|M.vanbaalenii_PYR-1 LKTYAEHCVDKYGLRPRIRFATTVRSADFDEAQGIWRLALDTADGPATLS
Mflv_4607|M.gilvum_PYR-GCK LKNYAKHCVKKYGLASRIRFGVTVVRAEFDEESTLWRLFTSTDE---ELT
MSMEG_0816|M.smegmatis_MC2_155 IKRYADDVADKYDVRRHIRFGTTVTGARWDEDDNVWQVSLTDGE---QLQ
MLBr_00065|M.leprae_Br4923 ILEYIKSTAVMHGIDKYIRLNHKVTGADWSSIENRWTVQVENNGTPRMIS
: * . .: :: * . * : :
MAB_0099|M.abscessus_ATCC_1997 ARYVISAVGG-YIDTKPGPDIPGINDFRGKVMRPNEWDHSYDYTGKRVAV
TH_2450|M.thermoresistible__bu ARFVISSVGG-YVNAR-ATDLEGLSDFTGKVLRPNCWDDGYDTRDKRVAV
Mb1428c|M.bovis_AF2122/97 ARFLISACG--ILTVPKLPDIDGVDSFEGVTMHTARWDHTQDLTGKRVGI
Rv1393c|M.tuberculosis_H37Rv ARFLISACG--ILTVPKLPDIDGVDSFEGVTMHTARWDHTQDLTGKRVGI
MMAR_2207|M.marinum_M TRFIINASG--VLTVPKLPDIAGVDSFAGVTMHTARWDHSQELTGKRVGI
MUL_1793|M.ulcerans_Agy99 TRFIINASG--VLTVPKLPDIAGVDSFAGVTMHTARWDHSQELTGKRVGI
MAV_3378|M.avium_104 ARFLISACG--VLTVPNLPDIDGVDSFAGITMHTARWDHGQDLRGKRVAV
Mvan_2671|M.vanbaalenii_PYR-1 ARFLVNAGG--VLTVPKLPDIAGVDSFAGVTMHTARWDHTQDLRGKRVAI
Mflv_4607|M.gilvum_PYR-GCK ARFVINASG--VLTRPKSPDIPGVGDFGGVTMHTSRWDHQQTLTGKRVAV
MSMEG_0816|M.smegmatis_MC2_155 ARFLITATG--FLSQPHTPDIPGITEFDGKVIHTTDWDDGCSLYGRRAAV
MLBr_00065|M.leprae_Br4923 CSFLFLCSGYYNYEQGYAPTFLGSEDFTGPIIHPQHWPEDLDYAAKNIVV
::. . * . : * .* * ::. * . :. :
MAB_0099|M.abscessus_ATCC_1997 IGTGSSGIQIAPAVAR-TAASVTTFQRTPAWIIPKPNPALSPRAQRILSA
TH_2450|M.thermoresistible__bu IGTGSSGAQIVSALSG-RVARLDVYQRTPNWILPRPDFALPRALQRVLEL
Mb1428c|M.bovis_AF2122/97 IGTGASAVQVIPEMAP-IVSHLTVFQRTPIWCFPKFDVPLPTAVRWAMRI
Rv1393c|M.tuberculosis_H37Rv IGTGASAVQVIPEMAP-IVSHLTVFQRTPIWCFPKFDVPLPTAVRWAMRI
MMAR_2207|M.marinum_M IGTGASAVQVIPEIAP-IVKHLTVFQRTPIWCFPKFDFPLPAALRWAMRI
MUL_1793|M.ulcerans_Agy99 IGTGASAVQVIPEIAP-IVKHLTVFQRTPIWCFPKFDFPLPAALRWAMRI
MAV_3378|M.avium_104 IGTGASAVQVIPEIAP-IVSSLTVFQRTPIWCFPKLDVPLPAPARWAMRF
Mvan_2671|M.vanbaalenii_PYR-1 IGTGASAVQVIPEIAP-IVERLTVFQRTPIWCFPKFDVPLSKTAQTMMRL
Mflv_4607|M.gilvum_PYR-GCK IGTGASAVQLIPSIAK-DVDTLTVFQRTPIWCLPKFDFAVPRPLSALLRL
MSMEG_0816|M.smegmatis_MC2_155 VGTGATAVQLIPELAE-RVAELTVYQRTPIWVVPKVDVRFPPAVRALFAR
MLBr_00065|M.leprae_Br4923 IGSGATAVTLVPALANSGAKHVTMLQRSPTYIVSQPAKDKIAARLNRWLP
:*:*::. : . :: . : **:* : ..:
MAB_0099|M.abscessus_ATCC_1997 P-LMLTLINASIAVSMDIVEFVLFHLLPLLPESVLRVLIPRYDNMARRWY
TH_2450|M.thermoresistible__bu PGVAAVLHNIGRAVFDLFFVVPIVHLMAHVPDRVLVRLLRGYDSLARFAF
Mb1428c|M.bovis_AF2122/97 P-GGKAVHRLLSQAFVEATFPIAAHYFAVFP----------LAKHMESAG
Rv1393c|M.tuberculosis_H37Rv P-GGKAVHRLLSQAFVEATFPIAAHYFAVFP----------LAKHMESAG
MMAR_2207|M.marinum_M P-GGKALQRLLSQAYVEATFPISAHYFTVFP----------LARWSAVLG
MUL_1793|M.ulcerans_Agy99 P-GGKALQRLLSQAYVEATFPISAHYFTVFP----------LARWSAVLG
MAV_3378|M.avium_104 P-GGKALQRLLSQAYVELTFPISAHYFTVIP----------LAKRMAALG
Mvan_2671|M.vanbaalenii_PYR-1 P-FGKSLQRLISQAFVELTFPLAAQYFTVNP----------MAKRMGAVG
Mflv_4607|M.gilvum_PYR-GCK APGAQIAARGASQAFVELTFPVAAHFHTAIP----------LASAIERAA
MSMEG_0816|M.smegmatis_MC2_155 VPLTQRVVRAITDAIYAFMVDTAVLKHRYFRR---------LNIAAADLG
MLBr_00065|M.leprae_Br4923 DKYAYTAVRWKNILRQSALYGACQKWPQRMR-----------NILLGHVA
.
MAB_0099|M.abscessus_ATCC_1997 RRLLRSTVQDPELRKALMPSYGILARRTILSSDFLQAVDAGEVQLVIEPI
TH_2450|M.thermoresistible__bu RVLLRAVVHDPQTRRRLMPAHGILAKRPIISGSYLPAFNDPRTHLITTPI
Mb1428c|M.bovis_AF2122/97 RRYLRQQVHDPVVREQLTPRYAVGCKRPGFHNTYLSTFNRDNVRLVTEPI
Rv1393c|M.tuberculosis_H37Rv RRYLRQQVHDPVVREQLTPRYAVGCKRPGFHNTYLSTFNRDNVRLVTEPI
MMAR_2207|M.marinum_M RRYLRQRVNDPVVRDQLTPRYAVGCKRPGFHNGYLSTFNRDNVQLVTEPI
MUL_1793|M.ulcerans_Agy99 RRYLRQRVDDPVVRDQLTPRYAVDCKRPGFHNGYLSTFNRDNVQLVTEPI
MAV_3378|M.avium_104 RAYLRRQVRDPAVREQLTPRYAVGCKRPGFHNGYLATFNRDNVRLVTEPI
Mvan_2671|M.vanbaalenii_PYR-1 RAYLRKQVDDPVLRDKLTPRYAVGCKRPGFHNTYLSTFNRDNVDLVTEPI
Mflv_4607|M.gilvum_PYR-GCK ISYMRRQVTDPVVREKLTPRYALGCKRPSFHNEYLKTFNRENVLLETNPI
MSMEG_0816|M.smegmatis_MC2_155 RLHLAASIRDPDLRSKLTPDYDFGCKRPTFSNSYYRTFTKPHVHLQADGI
MLBr_00065|M.leprae_Br4923 RRLPKGYDVQKHFGPHYNPWEQRLCLVP--DGDLFRAIRKGTVDMVTDAI
: * . . . :. . : *
MAB_0099|M.abscessus_ATCC_1997 ARVTEDGIDTADGAHHAVDLLVLATGYEIYTDP---EHYKPGAVRGRNGF
TH_2450|M.thermoresistible__bu ERITAAGVRTTDGVERPVDLIVTATGYELWTDP---ETYFPGTILGDAGF
Mb1428c|M.bovis_AF2122/97 DKITPTAVATTDGASHEIDVLVLATGFKVLDT----DSIPTYAVTGTGGA
Rv1393c|M.tuberculosis_H37Rv DKITPTAVATTDGASHEIDVLVLATGFKVLDT----DSIPTYAVTGTGGA
MMAR_2207|M.marinum_M EKITPTAVATDDGTDHEIDVLILATGFKVLDT----DDVLTYPVIGRAGR
MUL_1793|M.ulcerans_Agy99 EKITPTSVATDDGTDHEIDVLILATGFKVLDT----DDVLTYPVIGRAGR
MAV_3378|M.avium_104 DKITPDAVATTDGETHEIDVLILATGFKVMDP----DSVPTFAVTGSGGR
Mvan_2671|M.vanbaalenii_PYR-1 DKITGSGVSTTDGSLHEVDVLILATGFKVFAAHDGDDSVATFPVTGPGGR
Mflv_4607|M.gilvum_PYR-GCK TRVDETAVITADGVRHEIDVLVLATGFKVMES----DSMPTYSLRGVAGR
MSMEG_0816|M.smegmatis_MC2_155 DHVEPDGIVNADGSKTVIDTLVLATGFDLWEA-----NFPAIEVIGRQGR
MLBr_00065|M.leprae_Br4923 DRFTSTGIRLKSGNELRADIIVTATGLNLQLFG------------GAVAT
:. .: .* * :: *** .: * .
MAB_0099|M.abscessus_ATCC_1997 DLGTYYCDNDMRTYGGSALPGLPNRWMLVGPEGNQGQGWHAMVEANARHA
TH_2450|M.thermoresistible__bu DLALDYRENGLRSYGGTAHPRLPNRWEIVGPLAFVGVGWTDFVETMAEHA
Mb1428c|M.bovis_AF2122/97 SLSRFWDEHRLQAYEGVSVPGYPNFFTVFGPYGYVGSSYFALIETQAHHI
Rv1393c|M.tuberculosis_H37Rv SLSRFWDEHRLQAYEGVSVPGYPNFFTVFGPYGYVGSSYFALIETQAHHI
MMAR_2207|M.marinum_M SLSQFWEEHRAQAYQGVSVPGYPNFFAVFGPYGYVGSSYFALIETQTHHI
MUL_1793|M.ulcerans_Agy99 SLSQFWEEHRAQAYQGVSVPGYRNFFAVFGPYGYVGSSYFALIETQTHHI
MAV_3378|M.avium_104 SLSRFWDEHRLQAYEGVTVPGFPNLFTVFGPYGYVGSSYFALIEAQTHHI
Mvan_2671|M.vanbaalenii_PYR-1 SLARFWDDNRLQAYEGVSVPGFPNFFTVFGPYGYVGSSYFALIEAQTRHI
Mflv_4607|M.gilvum_PYR-GCK DQAQWWDENRLQAYEGVSVPGFPNHFSVFGPYGYNGSSYFALIEAQAGHI
MSMEG_0816|M.smegmatis_MC2_155 DLGKWWRETRFQAYQGVSMPYFPNYLSLAGPYAFLGLNFFNTMEYQMRLM
MLBr_00065|M.leprae_Br4923 VDGQPVDLAQTMSYKGMMLSGLPNMIYTVG---YTNASWTLKADLVSEFF
. :* * . * * . .: :
MAB_0099|M.abscessus_ATCC_1997 ARIIGASSRCHREVAEVSRRAFDRWVRKMAHQSKAIRLYATDCQPPLSTY
TH_2450|M.thermoresistible__bu VRIIDAARRRGADVVTVTDEAFGRWDARMRKAGKAARLYYTRCNPGVNTY
Mb1428c|M.bovis_AF2122/97 IRCLKRARRTGATRIEVTEEANARYFAEVMRRRHRQVFWQDSCRLAN-SY
Rv1393c|M.tuberculosis_H37Rv IRCLKRARRTGATRIEVTEEANARYFAEVMRRRHRQVFWQDSCRLAN-SY
MMAR_2207|M.marinum_M LRCLKRARRDGATRVEVTEEANARYFAEMMRRRYRQVFWQDSCRRAN-SY
MUL_1793|M.ulcerans_Agy99 LRCLKRARRDGATRVEVTEEANARYFAEMMRRRYRQVFWQDSCRRAN-SY
MAV_3378|M.avium_104 VRCLKRAQRLGATRVEVSEEANDRYFAEMMRRRHRQIFWQDSCRLAN-SY
Mvan_2671|M.vanbaalenii_PYR-1 VRCLDAARRRRATRVEVRREANDRYFAEMMRKRHRQIFWQDSCQLSN-SY
Mflv_4607|M.gilvum_PYR-GCK LRCLRHARTADSNYVEVREEANQRFFAEMLARRHTQVFWQDSCAGAN-SY
MSMEG_0816|M.smegmatis_MC2_155 ERLLGEVARRDARTFEVTEEANRRYLDRMTDALGDSLFTLGNCASAR-SY
MLBr_00065|M.leprae_Br4923 CRLLNYMNANDFDTVAVEYPGSDVEERPFMDFTPGYVLRSLDALPKQ---
* : * . . : .
MAB_0099|M.abscessus_ATCC_1997 FVNSKGETRYYRPQTVSEMNWFSKHSPISDYSL--RPVSMETKVRYDQSA
TH_2450|M.thermoresistible__bu YVNSQRDTVYHRPQTITESLVFAHRPPLTDYRFERRPAAARSAVRALRHA
Mb1428c|M.bovis_AF2122/97 YFDKNGDVP-LRPTTTVEAYWRSRRFDLGDYRISS---------------
Rv1393c|M.tuberculosis_H37Rv YFDKNGDVP-LRPTTTVEAYWRSRRFDLGDYRISS---------------
MMAR_2207|M.marinum_M YFDKNGDVP-LRPTTTVEAYWRGRHFDLDNYRFGR---------------
MUL_1793|M.ulcerans_Agy99 YFDKNGDVP-LRPTTTVEAYWRGRHFDLDDYRFGR---------------
MAV_3378|M.avium_104 YFDKNGDVP-LRPGTTPEVYWRSRRFDLDDYRFTG---------------
Mvan_2671|M.vanbaalenii_PYR-1 YFDQHGDVP-LRPASTPEAYWRSRRFPIDDYEFSC---------------
Mflv_4607|M.gilvum_PYR-GCK YFDKHGDVP-LRPTTTVESIWRSRRFDLADYRFERRPAKKADTAPQKVDT
MSMEG_0816|M.smegmatis_MC2_155 YFNPSGEATLLRPMTTRRAVAEASRFPLSDYTFA----------------
MLBr_00065|M.leprae_Br4923 ----GSRTPWRLNQNYLRDIRLIRRGKVADEGLLFAKKTTPVTV------
. . . : : : :
MAB_0099|M.abscessus_ATCC_1997 ------
TH_2450|M.thermoresistible__bu EGNEAV
Mb1428c|M.bovis_AF2122/97 ------
Rv1393c|M.tuberculosis_H37Rv ------
MMAR_2207|M.marinum_M ------
MUL_1793|M.ulcerans_Agy99 ------
MAV_3378|M.avium_104 ------
Mvan_2671|M.vanbaalenii_PYR-1 ------
Mflv_4607|M.gilvum_PYR-GCK AG----
MSMEG_0816|M.smegmatis_MC2_155 ------
MLBr_00065|M.leprae_Br4923 ------